Effects of recombinant dentin sialoprotein in dental pulp cells

Journal of Dental Research

Volumn 91, Issue 4, 2012, Pages 407-412

  Lee, S Y ^a   Kim, S Y ^a   Park, S H ^a   Kim, J J ^a   Jang, J H ^b   Kim, E C ^a  

^a Kyung Hee University   (South Korea)

^b Inha University School of Medicine   (South Korea)

Author keywords

BMP 2; dental pulp; dentin sialoprotein; differentiation; growth; noggin

Indexed keywords

ALKALINE PHOSPHATASE; BMP2 PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; CARRIER PROTEIN; DENTIN SIALOPHOSPHOPROTEIN; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; NOGGIN PROTEIN; ONCOPROTEIN; PHOSPHOPROTEIN; RECOMBINANT PROTEIN; SCLEROPROTEIN; SIALOGLYCOPROTEIN; SMAD1 PROTEIN; SMAD1 PROTEIN, HUMAN; SMAD5 PROTEIN; SMAD5 PROTEIN, HUMAN; SMAD8 PROTEIN; SMAD8 PROTEIN, HUMAN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CELL DIFFERENTIATION; CELL LINE; CELL MOTION; CELL PROLIFERATION; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; ODONTOBLAST; SIGNAL TRANSDUCTION; TIME; TOOTH DEVELOPMENT; TOOTH PULP;

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEINS; CARRIER PROTEINS; CELL DIFFERENTIATION; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; DENTAL PULP; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR MATRIX PROTEINS; HUMANS; I-KAPPA B PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; ODONTOBLASTS; ONCOGENE PROTEIN V-AKT; PHOSPHOPROTEINS; RECOMBINANT PROTEINS; RNA, MESSENGER; SIALOGLYCOPROTEINS; SIGNAL TRANSDUCTION; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TIME FACTORS; TOOTH CALCIFICATION; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA;

EID: 84859051687     PISSN: 00220345     EISSN: 15440591     Source Type: Journal    
DOI: 10.1177/0022034511436113     Document Type: Article

References (25)

1. About I, Bottero MJ, de Denato P, Camps J, Franquin JC, Mitsiadis TA. Human dentin production in vitro. Exp Cell Res. 2000 ; 258: 33-41 (Pubitemid 30461105)
2. Baldwin AS. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol. 1996 ; 14: 649-683
3. Boskey A, Spevak L, Tan M, Doty SB, Butler WT. Dentin sialoprotein (DSP) has limited effects on in vitro apatite formation and growth. Calcif Tissue Int. 2000 ; 67: 472-478 (Pubitemid 32221596)
4. Butler WT, Ritchie H. The nature and functional significance of dentin extracellular matrix proteins. Int J Dev Biol. 1995 ; 39: 169-179
5. Deng M, Shi J, Smith AJ, Jin Y. Effects of transforming growth factor β1 (TGF-1) and dentin non-collagenous proteins (DNCP) on human embryonic ectomesenchymal cells in a three-dimensional culture system. Arch Oral Biol. 2005 ; 50: 937-945 (Pubitemid 41393051)
6. Greenblatt MB, Shim JH, Zou W, Sitara D, Schweitzer M, Hu D, et al. The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice. J Clin Invest. 2010 ; 120: 2457-2473
7. Gronthos S, Mankani M, Brahim J, Robey PG, Shi S. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proc Natl Acad Sci USA. 2000 ; 97: 13625-13630
8. Hwang YC, Hwang IN, Oh WM, Park JC, Lee DS, Son HH. Influence of TGF-β1 on the expression of BSP, DSP, TGF-β1 receptor I and Smad proteins during reparative dentinogenesis. J Mol Histol. 2008 ; 39: 153-160
9. Kim YS, Min KS, Jeong DH, Jang JH, Kim HW, Kim EC. Effects of fibroblast growth factor-2 on the expression and regulation of chemokines in human dental pulp cells. J Endod. 2010 ; 36: 1824-1830
10. Kitagawa M, Ueda H, Iizuka S, Sakamoto K, Oka H, Kudo Y, et al. Immortalization and characterization of human dental pulp cells with odontoblastic differentiation. Arch Oral Biol. 2007 ; 52: 727-731 (Pubitemid 46898964)
11. Liu J, Jin T, Chang S, Ritchie HH, Smith AJ, Clarkson BH. Matrix and TGF-beta-related gene expression during human dental pulp stem cell (DPSC) mineralization. In Vitro Cell Dev Biol Anim. 2007 ; 43: 120-128 (Pubitemid 47091839)
12. MacDougall M, Simmons D, Luan X, Gu TT, DuPont BR. Assignment of dentin sialophosphoprotein (DSPP) to the critical DGI2 locus on human chromosome 4 band q21.3 by in situ hybridization. Cytogenet Cell Genet. 1997 ; 79: 121-122 (Pubitemid 28107831)
13. Magloire H, Joffre A, Bleicher F. An in vitro model of human dental pulp repair. J Dent Res. 1996 ; 75: 1971-1978 (Pubitemid 32770439)
14. Miyazono K, Maeda S, Imamura T. BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk. Cytokine Growth Factor Rev. 2005 ; 16: 251-263 (Pubitemid 40910315)
15. Nie X, Tian W, Zhang Y, Chen X, Dong R, Jiang M, et al. Induction of transforming growth factor-β 1 on dentine pulp cells in different culture patterns. Cell Biol Int. 2006 ; 30: 295-300
16. Rajpar MH, Koch MJ, Davies RM, Mellody KT, Kielty CM, Dixon MJ. Mutation of the signal peptide region of the bicistronic gene DSPP affects translocation to the endoplasmic reticulum and results in defective dentine biomineralization. Hum Mol Genet. 2002 ; 11: 2559-2565 (Pubitemid 35174686)
17. Sreenath T, Thyagarajan T, Hall B, Longenecker G, D'Souza R, Hong S, et al. Dentin sialophosphoprotein knockout mouse teeth display widened predentin zone and develop defective dentin mineralization similar to human dentinogenesis imperfecta type III. J Biol Chem. 2003 ; 278: 24874-24880 (Pubitemid 37548646)
18. Suzuki S, Sreenath T, Haruyama N, Honeycutt C, Terse A, Cho A, et al. Dentin sialoprotein and dentin phosphoprotein have distinct roles in dentin mineralization. Matrix Biol. 2009 ; 28: 221-229
19. Tang CH, Yang RS, Chien MY, Chen CC, Fu WM. Enhancement of bone morphogenetic protein-2 expression and bone formation by coumarin derivatives via p38 and ERK-dependent pathway in osteoblasts. Eur J Pharmacol. 2008 ; 579: 40-49
20. Wan DC, Pomerantz JH, Brunet LJ, Kim JB, Chou YF, Wu BM, et al. Noggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation. J Biol Chem. 2007 ; 282: 26450-26459 (Pubitemid 47443797)
21. Watanabe E, Takano Y. Ca-binding domains in the odontoblast layer of rat molars and incisors under normal and pathological conditions. Arch Histol Cytol. 2002 ; 65: 337-346 (Pubitemid 36019153)
22. Wei X, Ling J, Wu L, Liu L, Xiao Y. Expression of mineralization markers in dental pulp cells. J Endod. 2007 ; 33: 703-708
23. Wu L, Zhu F, Wu Y, Lin Y, Nie X, Jing W, et al. Dentin sialophosphoprotein-promoted mineralization and expression of odontogenic genes in adipose-derived stromal cells. Cells Tissues Organs. 2008 ; 187: 103-112 (Pubitemid 351252945)
24. Xiao GZ, Gopalakrishnan R, Jiang D, Reith E, Benson MD, Franceschi RT. Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells. J Bone Miner Res. 2002 ; 17: 101-110 (Pubitemid 33151001)
25. Zhang X, Zhao J, Li C, Gao S, Qiu C, Liu P, et al. DSPP mutation in dentinogenesis imperfecta Shields type II. Nat Genet. 2001 ; 27: 151-152 (Pubitemid 32157438)