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Volumn 9, Issue 3, 2014, Pages

A systematic in silico mining of the mechanistic implications and therapeutic potentials of estrogen receptor (ER)-a in breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR ALPHA; MICRORNA; ESTROGEN RECEPTOR ALPHA, HUMAN; HERBACEOUS AGENT; PROTEIN BINDING;

EID: 84897524099     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091894     Document Type: Article
Times cited : (6)

References (71)
  • 1
    • 31444449552 scopus 로고    scopus 로고
    • Epigenetic information and estrogen receptor alpha expression in breast cancer
    • DOI 10.1634/theoncologist.11-1-1
    • Giacinti L, Claudio PP, Lopez M, Giordano A (2006) Epigenetic information and estrogen receptor alpha expression in breast cancer. Oncologist 11: 1-8. doi:10.1634/theoncologist.11-1-1. PubMed: 16401708. (Pubitemid 43152681)
    • (2006) Oncologist , vol.11 , Issue.1 , pp. 1-8
    • Giacinti, L.1    Claudio, P.P.2    Lopez, M.3    Giordano, A.4
  • 2
    • 84856242855 scopus 로고    scopus 로고
    • Pomegranate sensitizes Tamoxifen action in ER-a positive breast cancer cells
    • doi:10.1007/s12079-011-0138-y. PubMed: 21706446
    • Banerjee S, Kambhampati S, Haque I, Banerjee SK (2011) Pomegranate sensitizes Tamoxifen action in ER-a positive breast cancer cells. J Cell Commun Signal 5: 317-324. doi:10.1007/s12079-011-0138-y. PubMed: 21706446.
    • (2011) J Cell Commun Signal , vol.5 , pp. 317-324
    • Banerjee, S.1    Kambhampati, S.2    Haque, I.3    Banerjee, S.K.4
  • 3
    • 0036154287 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators (SERMS) and their roles in breast cancer prevention
    • DOI 10.1016/S1471-4914(02)02282-7, PII S1471491401022493
    • Park WC, Jordan VC (2002) Selective estrogen receptor modulators (SERMS) and their roles in breast cancer prevention. Trends Mol Med 8: 82-88. doi:10.1016/S1471-4914(02)02282-7. PubMed: 11815274. (Pubitemid 34094444)
    • (2002) Trends in Molecular Medicine , vol.8 , Issue.2 , pp. 82-88
    • Park, W.-C.1    Jordan, V.C.2
  • 4
    • 84878107936 scopus 로고    scopus 로고
    • Selective oestrogen receptor modulators in prevention of breast cancer: An updated meta-analysis of individual participant data
    • doi:10.1016/S0140-6736(13)60140-3. PubMed: 23639488
    • Cuzick J, Sestak I, Bonanni B, Costantino JP, Cummings S, et al. (2013) Selective oestrogen receptor modulators in prevention of breast cancer: an updated meta-analysis of individual participant data. Lancet 381: 1827-1834. doi:10.1016/S0140-6736(13)60140-3. PubMed: 23639488.
    • (2013) Lancet , vol.381 , pp. 1827-1834
    • Cuzick, J.1    Sestak, I.2    Bonanni, B.3    Costantino, J.P.4    Cummings, S.5
  • 5
    • 79952114471 scopus 로고    scopus 로고
    • Third-generation SERMs may face uphill battle
    • doi:10.1093/jnci/djq477. PubMed: 21060064
    • Schmidt C (2010) Third-generation SERMs may face uphill battle. J Natl Cancer I 102: 1690-1692. doi:10.1093/jnci/djq477. PubMed: 21060064.
    • (2010) J Natl Cancer i , vol.102 , pp. 1690-1692
    • Schmidt, C.1
  • 6
    • 84878115405 scopus 로고    scopus 로고
    • Breast cancer prevention: SERMs come of age
    • doi:10.1016/S0140-6736(13)60443-2. PubMed: 23639489
    • Howell A, Evans DG (2013) Breast cancer prevention: SERMs come of age. Lancet 381: 1795-1797. doi:10.1016/S0140-6736(13)60443-2. PubMed: 23639489.
    • (2013) Lancet , vol.381 , pp. 1795-1797
    • Howell, A.1    Evans, D.G.2
  • 7
    • 84871346487 scopus 로고    scopus 로고
    • Clinical applications for microRNAs in cancer
    • doi:10.1038/clpt.2012.192. PubMed: 23212103
    • Nana-Sinkam S, Croce C (2012) Clinical applications for microRNAs in cancer. Clin Pharmacol Ther. doi:10.1038/clpt.2012.192. PubMed: 23212103.
    • (2012) Clin Pharmacol Ther
    • Nana-Sinkam, S.1    Croce, C.2
  • 8
    • 78650966289 scopus 로고    scopus 로고
    • Intracellular and extracellular microRNAs in breast cancer
    • doi: 10.1373/clinchem.2010.150730. PubMed: 21059829
    • Corcoran C, Friel AM, Duffy MJ, Crown J, O'Driscoll L (2011) Intracellular and extracellular microRNAs in breast cancer. Clin Chem 57: 18-32. doi: 10.1373/clinchem.2010.150730. PubMed: 21059829.
    • (2011) Clin Chem , vol.57 , pp. 18-32
    • Corcoran, C.1    Friel, A.M.2    Duffy, M.J.3    Crown, J.4    O'Driscoll, L.5
  • 9
    • 84879492700 scopus 로고    scopus 로고
    • MicroRNAs and drug resistance of breast cancer: Basic evidence and clinical applications
    • doi:10.1007/s12094-012-0929-5. PubMed: 22914907
    • Tian W, Chen J, He H, Deng Y (2012) MicroRNAs and drug resistance of breast cancer: basic evidence and clinical applications. Clin and Transl Oncol: 15: 335-342. doi:10.1007/s12094-012-0929-5. PubMed: 22914907.
    • (2012) Clin and Transl Oncol , vol.15 , pp. 335-342
    • Tian, W.1    Chen, J.2    He, H.3    Deng, Y.4
  • 10
    • 84874669929 scopus 로고    scopus 로고
    • Derailed estrogen signaling and breast cancer: An authentic couple
    • doi: 10.1210/er.2011-1057. PubMed: 22947396
    • Manavathi B, Dey O, Gajulapalli VNR, Bhatia RS, Bugide S, et al. (2013) Derailed estrogen signaling and breast cancer: an authentic couple. Endocr Rev 34: 1-32. doi: 10.1210/er.2011-1057. PubMed: 22947396.
    • (2013) Endocr Rev , vol.34 , pp. 1-32
    • Manavathi, B.1    Dey, O.2    Gajulapalli, V.N.R.3    Bhatia, R.S.4    Bugide, S.5
  • 11
    • 84860386584 scopus 로고    scopus 로고
    • MiRNAs and estrogen action
    • doi:10.1016/j.tem.2012.03.002. PubMed: 22503553
    • Klinge CM (2012) MiRNAs and estrogen action. Trends in Endocrin Met 23: 223-233. doi:10.1016/j.tem.2012.03.002. PubMed: 22503553.
    • (2012) Trends in Endocrin Met , vol.23 , pp. 223-233
    • Klinge, C.M.1
  • 12
    • 79551679816 scopus 로고    scopus 로고
    • Online resources of cancer data: Barriers, benefits and lessons
    • doi: 10.1093/bib/bbq010. PubMed: 20348133
    • Gadaleta E, Lemoine NR, Chelala C (2011) Online resources of cancer data: barriers, benefits and lessons. Brief Bioinform 12: 52-63. doi: 10.1093/bib/bbq010. PubMed: 20348133.
    • (2011) Brief Bioinform , vol.12 , pp. 52-63
    • Gadaleta, E.1    Lemoine, N.R.2    Chelala, C.3
  • 13
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • doi:10.1016/j.cell.2011.02.013. PubMed: 21376230
    • Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144: 646-674. doi:10.1016/j.cell.2011.02.013. PubMed: 21376230.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 14
    • 38949102687 scopus 로고    scopus 로고
    • Analysis of mechanistic pathway models in drug discovery: P38 pathway
    • DOI 10.1021/bp070084g
    • Hendriks BS, Hua F, Chabot JR (2008) Analysis of mechanistic pathway models in drug discovery: p38 pathway. Biotechnol Prog 24: 96-109. doi:10.1021/bp070084g. PubMed: 17918858. (Pubitemid 351231254)
    • (2008) Biotechnology Progress , vol.24 , Issue.1 , pp. 96-109
    • Hendriks, B.S.1    Hua, F.2    Chabot, J.R.3
  • 15
    • 58149193222 scopus 로고    scopus 로고
    • Human protein reference database-2009 update
    • doi:10.1093/nar/gkn892. PubMed: 18988627
    • Prasad TK, Goel R, Kandasamy K, Keerthikumar S, Kumar S, et al. (2009) Human protein reference database-2009 update. Nucleic Acids Res 37: D767-D772. doi:10.1093/nar/gkn892. PubMed: 18988627.
    • (2009) Nucleic Acids Res , vol.37
    • Prasad, T.K.1    Goel, R.2    Kandasamy, K.3    Keerthikumar, S.4    Kumar, S.5
  • 17
    • 84859204939 scopus 로고    scopus 로고
    • The IntAct molecular interaction database in 2012
    • doi:10.1093/nar/gkr1088. PubMed: 22121220
    • Kerrien S, Aranda B, Breuza L, Bridge A, Broackes-Carter F, et al. (2012) The IntAct molecular interaction database in 2012. Nucleic Acids Res 40: D841-D846. doi:10.1093/nar/gkr1088. PubMed: 22121220.
    • (2012) Nucleic Acids Res , vol.40
    • Kerrien, S.1    Aranda, B.2    Breuza, L.3    Bridge, A.4    Broackes-Carter, F.5
  • 18
    • 33947312507 scopus 로고    scopus 로고
    • HomoMINT: An inferred human network based on orthology mapping of protein interactions discovered in model organisms
    • doi:10.1186/1471-2105-6-S4-S21. PubMed: 16351748
    • Persico M, Ceol A, Gavrila C, Hoffmann R, Florio A, et al. (2005) HomoMINT: an inferred human network based on orthology mapping of protein interactions discovered in model organisms. BMC Bioinformatics 6: S21. doi:10.1186/1471-2105-6-S4-S21. PubMed: 16351748.
    • (2005) BMC Bioinformatics , vol.6
    • Persico, M.1    Ceol, A.2    Gavrila, C.3    Hoffmann, R.4    Florio, A.5
  • 20
    • 79551587720 scopus 로고    scopus 로고
    • Cytoscape 2.8: New features for data integration and network visualization
    • doi:10.1093/bioinformatics/btq675. PubMed: 21149340
    • Smoot ME, Ono K, Ruscheinski J, Wang P-L, Ideker T (2011) Cytoscape 2.8: new features for data integration and network visualization. Bioinformatics 27: 431-432. doi:10.1093/bioinformatics/btq675. PubMed: 21149340.
    • (2011) Bioinformatics , vol.27 , pp. 431-432
    • Smoot, M.E.1    Ono, K.2    Ruscheinski, J.3    Wang, P.-L.4    Ideker, T.5
  • 21
    • 19744382192 scopus 로고    scopus 로고
    • Science searches shift up a gear as Google starts Scholar engine
    • doi:10.1038/432423a. PubMed: 15565113
    • Butler D (2004) Science searches shift up a gear as Google starts Scholar engine. Nature 432: 423-423. doi:10.1038/432423a. PubMed: 15565113.
    • (2004) Nature , vol.432 , pp. 423-423
    • Butler, D.1
  • 22
    • 78651266827 scopus 로고    scopus 로고
    • MiRTarBase: A database curates experimentally validated microRNA-target interactions
    • doi:10.1093/nar/gkq1107. PubMed: 21071411
    • Hsu SD, Lin FM, Wu WY, Liang C, Huang WC, et al. (2011) miRTarBase: a database curates experimentally validated microRNA-target interactions. Nucleic Acids Res 39: D163-D169. doi:10.1093/nar/gkq1107. PubMed: 21071411.
    • (2011) Nucleic Acids Res , vol.39
    • Hsu, S.D.1    Lin, F.M.2    Wu, W.Y.3    Liang, C.4    Huang, W.C.5
  • 23
    • 84862176128 scopus 로고    scopus 로고
    • TarBase 6.0: Capturing the exponential growth of miRNA targets with experimental support
    • doi:10.1093/nar/gkr1161. PubMed: 22135297
    • Vergoulis T, Vlachos IS, Alexiou P, Georgakilas G, Maragkakis M, et al. (2012) TarBase 6.0: capturing the exponential growth of miRNA targets with experimental support. Nucleic Acids Res 40: D222-D229. doi:10.1093/nar/gkr1161. PubMed: 22135297.
    • (2012) Nucleic Acids Res , vol.40
    • Vergoulis, T.1    Vlachos, I.S.2    Alexiou, P.3    Georgakilas, G.4    Maragkakis, M.5
  • 24
    • 78651307694 scopus 로고    scopus 로고
    • StarBase: A database for exploring microRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data
    • doi:10.1093/nar/gkq1056. PubMed: 21037263
    • Yang JH, Li JH, Shao P, Zhou H, Chen YQ, et al. (2011) starBase: a database for exploring microRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data. Nucleic Acids Res 39: D202-D209. doi:10.1093/nar/ gkq1056. PubMed: 21037263.
    • (2011) Nucleic Acids Res , vol.39
    • Yang, J.H.1    Li, J.H.2    Shao, P.3    Zhou, H.4    Chen, Y.Q.5
  • 25
    • 58149186499 scopus 로고    scopus 로고
    • MiRecords: An integrated resource for microRNA-target interactions
    • doi:10.1093/nar/gkn851. PubMed: 18996891
    • Xiao F, Zuo Z, Cai G, Kang S, Gao X, et al. (2009) miRecords: an integrated resource for microRNA-target interactions. Nucleic Acids Res 37: D105-D110. doi:10.1093/nar/gkn851. PubMed: 18996891.
    • (2009) Nucleic Acids Res , vol.37
    • Xiao, F.1    Zuo, Z.2    Cai, G.3    Kang, S.4    Gao, X.5
  • 26
    • 79959805164 scopus 로고    scopus 로고
    • MiRWalk-database: Prediction of possible miRNA binding sites by "walking" the genes of three genomes
    • doi:10.1016/j.jbi.2011.05.002. PubMed: 21605702
    • Dweep H, Sticht C, Pandey P, Gretz N (2011) miRWalk-database: prediction of possible miRNA binding sites by "walking" the genes of three genomes. J Biomed Inform 44: 839-847. doi:10.1016/j.jbi.2011.05.002. PubMed: 21605702.
    • (2011) J Biomed Inform , vol.44 , pp. 839-847
    • Dweep, H.1    Sticht, C.2    Pandey, P.3    Gretz, N.4
  • 27
    • 70449372292 scopus 로고    scopus 로고
    • Accurate microRNA target prediction correlates with protein repression levels
    • doi:10.1186/1471-2105-10-295. PubMed: 19765283
    • Maragkakis M, Alexiou P, Papadopoulos GL, Reczko M, Dalamagas T, et al. (2009) Accurate microRNA target prediction correlates with protein repression levels. BMC Bioinformatics 10: 295. doi:10.1186/1471-2105-10-295. PubMed: 19765283.
    • (2009) BMC Bioinformatics , vol.10 , pp. 295
    • Maragkakis, M.1    Alexiou, P.2    Papadopoulos, G.L.3    Reczko, M.4    Dalamagas, T.5
  • 28
    • 38549124383 scopus 로고    scopus 로고
    • The microRNA.org resource: Targets and expression
    • DOI 10.1093/nar/gkm995
    • Betel D, Wilson M, Gabow A, Marks DS, Sander C (2008) The microRNA. org resource: targets and expression. Nucleic Acids Res 36: D149-D153. doi:10.1093/nar/gkm995. PubMed: 18158296. (Pubitemid 351149712)
    • (2008) Nucleic Acids Research , vol.36 , Issue.SUPPL. 1
    • Betel, D.1    Wilson, M.2    Gabow, A.3    Marks, D.S.4    Sander, C.5
  • 29
    • 0346094457 scopus 로고    scopus 로고
    • Prediction of Mammalian MicroRNA Targets
    • DOI 10.1016/S0092-8674(03)01018-3
    • Lewis BP, Shih IH, Jones Rhoades MW, Bartel DP, Burge CB (2003) Prediction of mammalian microRNA targets. Cell 115: 787-798. doi:10.1016/S0092-8674(03)01018-3. PubMed: 14697198. (Pubitemid 38058492)
    • (2003) Cell , vol.115 , Issue.7 , pp. 787-798
    • Lewis, B.P.1    Shih, I.-H.2    Jones-Rhoades, M.W.3    Bartel, D.P.4    Burge, C.B.5
  • 30
    • 84874084179 scopus 로고    scopus 로고
    • Molecular mechanisms of selective estrogen receptor modulator activity in human breast cancer cells: Identification of novel nuclear cofactors of antiestrogen-ERalpha complexes by interaction proteomics
    • doi:10.1021/pr300753u. PubMed: 23170835
    • Cirillo F, Nassa G, Tarallo R, Stellato C, De Filippo MR, et al. (2013) Molecular mechanisms of selective estrogen receptor modulator activity in human breast cancer cells: identification of novel nuclear cofactors of antiestrogen-ERalpha complexes by interaction proteomics. J Proteome Res 12: 421-431. doi:10.1021/pr300753u. PubMed: 23170835.
    • (2013) J Proteome Res , vol.12 , pp. 421-431
    • Cirillo, F.1    Nassa, G.2    Tarallo, R.3    Stellato, C.4    De Filippo, M.R.5
  • 31
    • 54549097590 scopus 로고    scopus 로고
    • Genes responsive to both oxidant stress and loss of estrogen receptor function identify a poor prognosis group of estrogen receptor positive primary breast cancers
    • doi:10.1186/bcr2120. PubMed: 18631401
    • Yau C, Benz CC (2008) Genes responsive to both oxidant stress and loss of estrogen receptor function identify a poor prognosis group of estrogen receptor positive primary breast cancers. Breast Cancer Res 10: R61. doi:10.1186/bcr2120. PubMed: 18631401.
    • (2008) Breast Cancer Res , vol.10
    • Yau, C.1    Benz, C.C.2
  • 34
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • doi:10.1038/nprot.2008.211. PubMed: 19131956
    • Da Wei Huang BTS, Lempicki RA (2008) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57. doi:10.1038/nprot.2008.211. PubMed: 19131956.
    • (2008) Nat Protoc , vol.4 , pp. 44-57
    • Da Wei Huang, B.T.S.1    Lempicki, R.A.2
  • 35
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
    • doi:10.1093/nar/gkn923. PubMed: 19033363
    • Sherman BT, Lempicki RA (2009) Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 37: 1-13. doi:10.1093/nar/gkn923. PubMed: 19033363.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1-13
    • Sherman, B.T.1    Lempicki, R.A.2
  • 37
    • 79951882529 scopus 로고    scopus 로고
    • Prediction of associations between microRNAs and gene expression in glioma biology
    • doi:10.1371/journal.pone.0014681. PubMed: 21358821
    • Wuchty S, Arjona D, Li A, Kotliarov Y, Walling J, et al. (2011) Prediction of associations between microRNAs and gene expression in glioma biology. PLoS One 6: e14681. doi:10.1371/journal.pone.0014681. PubMed: 21358821.
    • (2011) PLoS One , vol.6
    • Wuchty, S.1    Arjona, D.2    Li, A.3    Kotliarov, Y.4    Walling, J.5
  • 38
    • 49949117302 scopus 로고    scopus 로고
    • Widespread changes in protein synthesis induced by microRNAs
    • doi:10.1038/nature07228. PubMed: 18668040
    • Selbach M, Schwanhausser B, Thierfelder N, Fang Z, Khanin R, et al. (2008) Widespread changes in protein synthesis induced by microRNAs. Nature 455: 58-63. doi:10.1038/nature07228. PubMed: 18668040.
    • (2008) Nature , vol.455 , pp. 58-63
    • Selbach, M.1    Schwanhausser, B.2    Thierfelder, N.3    Fang, Z.4    Khanin, R.5
  • 39
    • 0032446607 scopus 로고    scopus 로고
    • The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
    • DOI 10.1016/S0092-8674(00)81717-1
    • Shiau AK, Barstad D, Loria PM, Cheng L, Kushner PJ, et al. (1998) The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell 95: 927-937. doi:10.1016/S0092-8674(00) 81717-1. PubMed: 9875847. (Pubitemid 29019045)
    • (1998) Cell , vol.95 , Issue.7 , pp. 927-937
    • Shiau, A.K.1    Barstad, D.2    Loria, P.M.3    Cheng, L.4    Kushner, P.J.5    Agard, D.A.6    Greene, G.L.7
  • 40
    • 84864199587 scopus 로고    scopus 로고
    • ZINC: A free tool to discover chemistry for biology
    • doi:10.1021/ci3001277. PubMed: 22587354
    • Irwin JJ, Sterling T, Mysinger MM, Bolstad ES, Coleman RG (2012) ZINC: a free tool to discover chemistry for biology. J Chem Inf Model 52: 1757-1768.doi:10.1021/ci3001277. PubMed: 22587354.
    • (2012) J Chem Inf Model , vol.52 , pp. 1757-1768
    • Irwin, J.J.1    Sterling, T.2    Mysinger, M.M.3    Bolstad, E.S.4    Coleman, R.G.5
  • 41
    • 33750991346 scopus 로고    scopus 로고
    • Benchmarking sets for molecular docking
    • DOI 10.1021/jm0608356
    • Huang N, Shoichet BK, Irwin JJ (2006) Benchmarking sets for molecular docking. J Med Chem 49: 6789-6801. doi:10.1021/jm0608356. PubMed: 17154509. (Pubitemid 44749746)
    • (2006) Journal of Medicinal Chemistry , vol.49 , Issue.23 , pp. 6789-6801
    • Huang, N.1    Shoichet, B.K.2    Irwin, J.J.3
  • 42
    • 66449110287 scopus 로고    scopus 로고
    • DOCK 6: Combining techniques to model RNA-small molecule complexes
    • doi:10.1261/rna.1563609. PubMed: 19369428
    • Lang PT, Brozell SR, Mukherjee S, Pettersen EF, Meng EC, et al. (2009) DOCK 6: Combining techniques to model RNA-small molecule complexes. RNA 15: 1219-1230. doi:10.1261/rna.1563609. PubMed: 19369428.
    • (2009) RNA , vol.15 , pp. 1219-1230
    • Lang, P.T.1    Brozell, S.R.2    Mukherjee, S.3    Pettersen, E.F.4    Meng, E.C.5
  • 43
    • 4444221565 scopus 로고    scopus 로고
    • UCSF Chimera-a visualization system for exploratory research and analysis
    • doi:10.1002/jcc.20084. PubMed: 15264254
    • Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, et al. (2004) UCSF Chimera-a visualization system for exploratory research and analysis. J Comput Chem 25: 1605-1612. doi:10.1002/jcc.20084. PubMed: 15264254.
    • (2004) J Comput Chem , vol.25 , pp. 1605-1612
    • Pettersen, E.F.1    Goddard, T.D.2    Huang, C.C.3    Couch, G.S.4    Greenblatt, D.M.5
  • 44
    • 34547559704 scopus 로고    scopus 로고
    • PDB2PQR: Expanding and upgrading automated preparation of biomolecular structures for molecular simulations
    • doi:10.1093/nar/gkm276. PubMed: 17488841
    • Dolinsky TJ, Czodrowski P, Li H, Nielsen JE, Jensen JH, et al. (2007) PDB2PQR: expanding and upgrading automated preparation of biomolecular structures for molecular simulations. Nucleic Acids Res 35: W522-W525. doi:10.1093/nar/gkm276. PubMed: 17488841.
    • (2007) Nucleic Acids Res , vol.35
    • Dolinsky, T.J.1    Czodrowski, P.2    Li, H.3    Nielsen, J.E.4    Jensen, J.H.5
  • 45
    • 79952709519 scopus 로고    scopus 로고
    • PROC: An open-source package for R and S+ to analyze and compare ROC curves
    • doi:10.1186/1471-2105-12-77. PubMed: 21414208
    • Robin X, Turck N, Hainard A, Tiberti N, Lisacek F, et al. (2011) pROC: an open-source package for R and S+ to analyze and compare ROC curves. BMC Bioinformatics 12: 77. doi:10.1186/1471-2105-12-77. PubMed: 21414208.
    • (2011) BMC Bioinformatics , vol.12 , pp. 77
    • Robin, X.1    Turck, N.2    Hainard, A.3    Tiberti, N.4    Lisacek, F.5
  • 47
    • 0029665114 scopus 로고    scopus 로고
    • Force field development and conformational search strategy in the simulation of biomolecular recognition processes
    • PubMed: 8674683
    • Tenette C, Smith JC, Topham CM (1996) Force field development and conformational search strategy in the simulation of biomolecular recognition processes. Biochem Soc Trans 24: 268-274. PubMed: 8674683.
    • (1996) Biochem Soc Trans , vol.24 , pp. 268-274
    • Tenette, C.1    Smith, J.C.2    Topham, C.M.3
  • 48
    • 0029878720 scopus 로고    scopus 로고
    • VMD: Visual molecular dynamics
    • DOI 10.1016/0263-7855(96)00018-5
    • Humphrey W, Dalke A, Schulten K (1996) VMD: visual molecular dynamics. J Mol Graph Model; 14: 33-38. doi:10.1016/0263-7855(96)00018-5. PubMed: 8744570. (Pubitemid 26152973)
    • (1996) Journal of Molecular Graphics , vol.14 , Issue.1 , pp. 33-38
    • Humphrey, W.1    Dalke, A.2    Schulten, K.3
  • 49
    • 26944498633 scopus 로고    scopus 로고
    • Prediction and validation of microRNAs and their targets
    • DOI 10.1016/j.febslet.2005.09.040, PII S0014579305011543, RNAi: Mechanisms, Biology and Applications
    • Bentwich I (2005) Prediction and validation of microRNAs and their targets. FEBS Lett 579: 5904-5910. doi:10.1016/j.febslet.2005.09.040. PubMed: 16214134. (Pubitemid 41484136)
    • (2005) FEBS Letters , vol.579 , Issue.26 , pp. 5904-5910
    • Bentwich, I.1
  • 50
    • 79952791439 scopus 로고    scopus 로고
    • Practical Aspects of microRNA Target Prediction
    • doi:10.2174/156652411794859250. PubMed: 21342132
    • Witkos TM, Koscianska E, Krzyzosiak WJ (2011) Practical Aspects of microRNA Target Prediction. Curr Mol Med 11: 93-109. doi:10.2174/ 156652411794859250. PubMed: 21342132.
    • (2011) Curr Mol Med , vol.11 , pp. 93-109
    • Witkos, T.M.1    Koscianska, E.2    Krzyzosiak, W.J.3
  • 51
    • 74549134502 scopus 로고    scopus 로고
    • Human cancer protein-protein interaction network: A structural perspective
    • doi:10.1371/journal.pcbi. 1000601. PubMed: 20011507
    • Kar G, Gursoy A, Keskin O (2009) Human cancer protein-protein interaction network: a structural perspective. PLoS Comput Biol 5: e1000601. doi:10.1371/journal.pcbi.1000601. PubMed: 20011507.
    • (2009) PLoS Comput Biol , vol.5
    • Kar, G.1    Gursoy, A.2    Keskin, O.3
  • 52
    • 77950672712 scopus 로고    scopus 로고
    • Network-based identification of novel cancer genes
    • doi:10.1074/mcp.M900227-MCP200. PubMed: 19959820
    • Ostlund G, Lindskog M, Sonnhammer EL (2010) Network-based identification of novel cancer genes. Mol Cell Proteomics 9: 648-655. doi:10.1074/mcp.M900227- MCP200. PubMed: 19959820.
    • (2010) Mol Cell Proteomics , vol.9 , pp. 648-655
    • Ostlund, G.1    Lindskog, M.2    Sonnhammer, E.L.3
  • 53
    • 43749096790 scopus 로고    scopus 로고
    • Predicting cancer involvement of genes from heterogeneous data
    • doi:10.1186/1471-2105-9-172. PubMed: 18371197
    • Aragues R, Sander C, Oliva B (2008) Predicting cancer involvement of genes from heterogeneous data. BMC Bioinformatics 9: 172. doi:10.1186/1471-2105- 9-172. PubMed: 18371197.
    • (2008) BMC Bioinformatics , vol.9 , pp. 172
    • Aragues, R.1    Sander, C.2    Oliva, B.3
  • 54
    • 58149305794 scopus 로고    scopus 로고
    • An empirical framework for binary interactome mapping
    • doi:10.1038/nmeth.1280. PubMed: 19060904
    • Venkatesan K, Rual JF, Vazquez A, Stelzl U, Lemmens I, et al. (2008) An empirical framework for binary interactome mapping. Nat Methods 6: 83-90. doi:10.1038/nmeth.1280. PubMed: 19060904.
    • (2008) Nat Methods , vol.6 , pp. 83-90
    • Venkatesan, K.1    Rual, J.F.2    Vazquez, A.3    Stelzl, U.4    Lemmens, I.5
  • 55
    • 51149092061 scopus 로고    scopus 로고
    • The role of hormonal therapy in the management of hormonal-receptor- positive breast cancer with co-expression of HER2
    • doi:10.1038/ncponc1179. PubMed: 18607391
    • Prat A, Baselga J (2008) The role of hormonal therapy in the management of hormonal-receptor-positive breast cancer with co-expression of HER2. Nat Clin Practi Oncol 5: 531-542. doi:10.1038/ncponc1179. PubMed: 18607391.
    • (2008) Nat Clin Practi Oncol , vol.5 , pp. 531-542
    • Prat, A.1    Baselga, J.2
  • 57
    • 78149501152 scopus 로고    scopus 로고
    • The molecular mechanisms underlying the pharmacological actions of ER modulators: Implications for new drug discovery in breast cancer
    • doi:10.1016/j.coph.2010.09.007. PubMed: 20926342
    • McDonnell DP, Wardell SE (2010) The molecular mechanisms underlying the pharmacological actions of ER modulators: implications for new drug discovery in breast cancer. Curr Opin Pharmacol 10: 620-628. doi:10.1016/j.coph.2010.09.007. PubMed: 20926342.
    • (2010) Curr Opin Pharmacol , vol.10 , pp. 620-628
    • McDonnell, D.P.1    Wardell, S.E.2
  • 58
    • 9644267549 scopus 로고    scopus 로고
    • Binding of MCF-7 cell mitochondrial proteins and recombinant human estrogen receptors α and β to human mitochondrial DNA estrogen response elements
    • DOI 10.1002/jcb.20178
    • Chen JQ, Eshete M, Alworth WL, Yager JD (2004) Binding of MCF-7 cell mitochondrial proteins and recombinant human estrogen receptors a and b to human mitochondrial dna estrogen response elements. J Cell Biochem 93: 358-373. doi:10.1002/jcb.20178. PubMed: 15368362. (Pubitemid 44264212)
    • (2004) Journal of Cellular Biochemistry , vol.93 , Issue.2 , pp. 358-373
    • Chen, J.Q.1    Eshete, M.2    Alworth, W.L.3    Yager, J.D.4
  • 59
    • 0141841796 scopus 로고    scopus 로고
    • Enhanced mitochondrial gene transcript, ATP, Bcl-2 protein levels, and altered glutathione distribution in ethinyl estradiol-treated cultured female rat hepatocytes
    • DOI 10.1093/toxsci/kfg183
    • Chen J, Delannoy M, Odwin S, He P, Trush MA, et al. (2003) Enhanced mitochondrial gene transcript, ATP, bcl-2 protein levels, and altered glutathione distribution in ethinyl estradiol-treated cultured female rat hepatocytes. Toxicol Sci 75: 271-278. doi:10.1093/toxsci/kfg183. PubMed: 12857939. (Pubitemid 37220274)
    • (2003) Toxicological Sciences , vol.75 , Issue.2 , pp. 271-278
    • Chen, J.1    Delannoy, M.2    Odwin, S.3    He, P.4    Trush, M.A.5    Yager, J.D.6
  • 60
    • 0034674065 scopus 로고    scopus 로고
    • Estrogen receptor a rapidly activates the IGF-1 receptor pathway
    • DOI 10.1074/jbc.M910345199
    • Kahlert S, Nuedling S, van Eickels M, Vetter H, Meyer R, et al. (2000) Estrogen receptor alpha rapidly activates the IGF-1 receptor pathway. J Biol Chem 275: 18447-18453. doi:10.1074/jbc.M910345199. PubMed: 10749889. (Pubitemid 30414803)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.24 , pp. 18447-18453
    • Kahlert, S.1    Nuedling, S.2    Van Eickels, M.3    Vetter, H.4    Meyer, R.5    Grohe, C.6
  • 61
    • 0034727094 scopus 로고    scopus 로고
    • Interaction of oestrogen receptor with the regulatory subunit of phosphatidy-linositol-3-OH kinase
    • doi:10.1038/35035131. PubMed: 11029009
    • Simoncini T, Hafezi Moghadam A, Brazil DP, Ley K, Chin WW, et al. (2000) Interaction of oestrogen receptor with the regulatory subunit of phosphatidy-linositol-3-OH kinase. Nature 407: 538-541. doi:10.1038/35035131. PubMed: 11029009.
    • (2000) Nature , vol.407 , pp. 538-541
    • Simoncini, T.1    Hafezi Moghadam, A.2    Brazil, D.P.3    Ley, K.4    Chin, W.W.5
  • 62
    • 79955836460 scopus 로고    scopus 로고
    • A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells
    • doi:10.1016/j.cell.2011.03.042. PubMed: 21549415
    • Hah N, Danko CG, Core L, Waterfall JJ, Siepel A, et al. (2011) A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells. Cell 145: 622-634. doi:10.1016/j.cell.2011.03.042. PubMed: 21549415.
    • (2011) Cell , vol.145 , pp. 622-634
    • Hah, N.1    Danko, C.G.2    Core, L.3    Waterfall, J.J.4    Siepel, A.5
  • 63
    • 84855657375 scopus 로고    scopus 로고
    • Estradiol-activated estrogen receptor a does not regulate mature microRNAs in T47D breast cancer cells
    • doi:10.1016/j.jsbmb.2011.10.008. PubMed: 22079223
    • Katchy A, Edvardsson K, Aydogdu E, Williams C (2012) Estradiol-activated estrogen receptor a does not regulate mature microRNAs in T47D breast cancer cells. J Steroid Biochem128: 145-153. doi:10.1016/j.jsbmb.2011.10.008. PubMed: 22079223.
    • (2012) J Steroid Biochem , vol.128 , pp. 145-153
    • Katchy, A.1    Edvardsson, K.2    Aydogdu, E.3    Williams, C.4
  • 64
    • 84870385656 scopus 로고    scopus 로고
    • Estrogen receptor alpha signaling regulates breast tumor-initiating cells by down-regulating miR-140 which targets the transcription factor SOX2
    • doi:10.1074/jbc.M112.404871. PubMed: 23060440
    • Zhang Y, Eades G, Yao Y, Li Q, Zhou Q (2012) Estrogen receptor alpha signaling regulates breast tumor-initiating cells by down-regulating miR-140 which targets the transcription factor SOX2. J Biol Chem 287: 41514-41522. doi:10.1074/jbc.M112.404871. PubMed: 23060440.
    • (2012) J Biol Chem , vol.287 , pp. 41514-41522
    • Zhang, Y.1    Eades, G.2    Yao, Y.3    Li, Q.4    Zhou, Q.5
  • 65
    • 74249112787 scopus 로고    scopus 로고
    • Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection
    • doi:10.1126/science.1178178. PubMed: 19965718
    • Lanford RE, Hildebrandt-Eriksen ES, Petri A, Persson R, Lindow M, et al. (2010) Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science 327: 198-201. doi:10.1126/science.1178178. PubMed: 19965718.
    • (2010) Science , vol.327 , pp. 198-201
    • Lanford, R.E.1    Hildebrandt-Eriksen, E.S.2    Petri, A.3    Persson, R.4    Lindow, M.5
  • 66
    • 84875150414 scopus 로고    scopus 로고
    • The holistic integration of virtual screening in drug discovery
    • doi:10.1016/j.drudis.2013. 01.007. PubMed: 23340112
    • Tanrikulu Y, Krüger B, Proschak E (2013) The holistic integration of virtual screening in drug discovery. Drug Discov Today. doi:10.1016/j.drudis. 2013. 01.007. PubMed: 23340112.
    • (2013) Drug Discov Today
    • Tanrikulu, Y.1    Krüger, B.2    Proschak, E.3
  • 67
    • 84877583263 scopus 로고    scopus 로고
    • Discovery of natural estrogen receptor modulators with structure-based virtual screening
    • doi:10.1016/j.bmcl.2013.03.105. PubMed: 23608764
    • Cao X, Jiang J, Zhang S, Zhu L, Zou J, et al. (2013) Discovery of natural estrogen receptor modulators with structure-based virtual screening. Bioorg Med Chem Lett. doi:10.1016/j.bmcl.2013.03.105. PubMed: 23608764.
    • (2013) Bioorg Med Chem Lett
    • Cao, X.1    Jiang, J.2    Zhang, S.3    Zhu, L.4    Zou, J.5
  • 68
    • 77952723621 scopus 로고    scopus 로고
    • "TieredScreen"-Layered virtual screening tool for the identification of novel estrogen receptor alpha modulators
    • doi:10.1002/minf.20100034
    • Yang YD, Carta G, Peters MB, Price T, Boyle NO, et al. (2010) "tieredScreen"-Layered virtual screening tool for the identification of novel estrogen receptor alpha modulators. Mol Inform 29: 421-430. doi:10.1002/minf.20100034.
    • (2010) Mol Inform , vol.29 , pp. 421-430
    • Yang, Y.D.1    Carta, G.2    Peters, M.B.3    Price, T.4    Boyle, N.O.5
  • 69
    • 41949132916 scopus 로고    scopus 로고
    • Flexible ligand docking to multiple receptor conformations: A practical alternative
    • doi:10.1016/j.sbi.2008.01.004. PubMed: 18302984
    • Totrov M, Abagyan R (2008) Flexible ligand docking to multiple receptor conformations: a practical alternative. Curr Opin Struc Biol 18: 178-184. doi:10.1016/j.sbi.2008.01.004. PubMed: 18302984.
    • (2008) Curr Opin Struc Biol , vol.18 , pp. 178-184
    • Totrov, M.1    Abagyan, R.2
  • 70
    • 0028693767 scopus 로고
    • Prediction of the binding sites of huperzine A in acetylcholinesterase by docking studies
    • doi:10.1007/BF00124014. PubMed: 7738603
    • Pang Y-P, Kozikowski AP (1994) Prediction of the binding sites of huperzine A in acetylcholinesterase by docking studies. J Comput Aid Mol Des 8: 669-681. doi:10.1007/BF00124014. PubMed: 7738603.
    • (1994) J Comput Aid Mol des , vol.8 , pp. 669-681
    • Pang, Y.-P.1    Kozikowski, A.P.2
  • 71
    • 46849105028 scopus 로고    scopus 로고
    • Ensemble-based virtual screening reveals potential novel antiviral compounds for avian influenza neuraminidase
    • DOI 10.1021/jm8001197
    • Cheng LS, Amaro RE, Xu D, Li WW, Arzberger PW, et al. (2008) Ensemble-based virtual screening reveals potential novel antiviral compounds for avian influenza neuraminidase. J Med Chem 51: 3878-3894. doi: 10.1021/jm8001197. PubMed: 18558668. (Pubitemid 351956517)
    • (2008) Journal of Medicinal Chemistry , vol.51 , Issue.13 , pp. 3878-3894
    • Cheng, L.S.1    Amaro, R.E.2    Xu, D.3    Li, W.W.4    Arzberger, P.W.5    McCammon, J.A.6


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