'TieredScreen' - Layered virtual screening tool for the identification of novel estrogen receptor alpha modulators

Molecular Informatics

Volumn 29, Issue 5, 2010, Pages 421-430

  Yang, Yidong ^a   Carta, Giorgio ^a   Peters, Martin B ^a   Price, Trevor ^a   O'Boyle, Niamh ^a   Knox, Andrew J S ^a   Fayne, Darren ^a   Williams, D Clive ^a   Meegan, Mary J ^a   Lloyd, David G ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Docking; Drug Design; Estrogen receptor; Molecular modelling; Nuclear hormone receptor; Pharmacophore; Shape matching; Virtual screening

Indexed keywords

DOCKING; DRUG DESIGN; ESTROGEN RECEPTOR; NANOMOLAR; NUCLEAR HORMONE RECEPTOR; PHARMACOPHORES; SCREENING TOOL; SHAPE MATCHING; VIRTUAL SCREENING; WORK-FLOWS;

CHEMICAL REACTIONS;

ESTROGEN RECEPTOR ALPHA;

ANALYTIC METHOD; ARTICLE; AUTOMATION; CELL PROLIFERATION; CELL VIABILITY; CLINICAL PROTOCOL; CONTROLLED STUDY; CRYSTAL STRUCTURE; DATA BASE; HUMAN; HUMAN CELL; HYDROGEN BOND; MOLECULAR DOCKING; MOLECULAR MODEL; PERFORMANCE; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; SCREENING; VIRTUAL REALITY;

EID: 77952723621     PISSN: 18681743     EISSN: 18681751     Source Type: Journal    
DOI: 10.1002/minf.201000034     Document Type: Article

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