Reactive oxygen species production and mitochondrial dysfunction in white blood cells are not valid biomarkers of ageing in the very old

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Wiley, Laura ^a   Ashok, Deepthi ^a   Martin Ruiz, Carmen ^a   Talbot, Duncan C S ^b   Collerton, Joanna ^a   Kingston, Andrew ^a   Davies, Karen ^a   Chinnery, Patrick F ^a   Catt, Michael ^a   Jagger, Carol ^a   Kirkwood, Thomas B L ^a   Von Zglinicki, Thomas ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNILEVER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

AGED; AGING; ARTICLE; CELL ASSAY; CELL FUNCTION; CELL POPULATION; CELL VOLUME; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKOCYTE; LONGITUDINAL STUDY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MONOCYTE; OXIDATIVE STRESS; PERIPHERAL BLOOD MONONUCLEAR CELL; RELIABILITY; SENESCENCE; VALIDITY; VERY ELDERLY; CELL AGING; CELL SURVIVAL; METABOLISM; MONONUCLEAR CELL; PATHOLOGY; REPRODUCIBILITY;

AGED, 80 AND OVER; AGING; BIOMARKERS; CELL AGING; CELL SURVIVAL; HUMANS; LEUKOCYTES; LEUKOCYTES, MONONUCLEAR; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; REPRODUCIBILITY OF RESULTS; SUPEROXIDES;

EID: 84897517333     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091005     Document Type: Article

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