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Volumn 7, Issue 12, 2012, Pages

Functional Differences between Mitochondrial Haplogroup T and Haplogroup H in HEK293 Cybrid Cells

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE;

EID: 84871554974     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052367     Document Type: Article
Times cited : (45)

References (60)
  • 1
    • 1642285792 scopus 로고    scopus 로고
    • The incomplete natural history of mitochondria
    • Ballard JW, Whitlock MC, (2004) The incomplete natural history of mitochondria. Mol Ecol 13: 729-744.
    • (2004) Mol Ecol , vol.13 , pp. 729-744
    • Ballard, J.W.1    Whitlock, M.C.2
  • 2
    • 0033525773 scopus 로고    scopus 로고
    • Mitochondrial diseases in man and mouse
    • Wallace DC, (1999) Mitochondrial diseases in man and mouse. Science 283: 1482-1488.
    • (1999) Science , vol.283 , pp. 1482-1488
    • Wallace, D.C.1
  • 3
    • 17744393686 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in human disease
    • Taylor RW, Turnbull DM, (2005) Mitochondrial DNA mutations in human disease. Nat Rev Genet 6: 389-402.
    • (2005) Nat Rev Genet , vol.6 , pp. 389-402
    • Taylor, R.W.1    Turnbull, D.M.2
  • 4
    • 23844558266 scopus 로고    scopus 로고
    • A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine
    • Wallace DC, (2005) A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet 39: 359-407.
    • (2005) Annu Rev Genet , vol.39 , pp. 359-407
    • Wallace, D.C.1
  • 6
    • 33947373403 scopus 로고    scopus 로고
    • Mitochondrial DNA G10398A polymorphism imparts maternal Haplogroup N a risk for breast and esophageal cancer
    • Darvishi K, Sharma S, Bhat AK, Rai E, Bamezai RN, (2007) Mitochondrial DNA G10398A polymorphism imparts maternal Haplogroup N a risk for breast and esophageal cancer. Cancer Lett 249: 249-255.
    • (2007) Cancer Lett , vol.249 , pp. 249-255
    • Darvishi, K.1    Sharma, S.2    Bhat, A.K.3    Rai, E.4    Bamezai, R.N.5
  • 9
    • 33748509495 scopus 로고    scopus 로고
    • Mitochondrial DNA haplogroups in Spanish patients with hypertrophic cardiomyopathy
    • Castro MG, Huerta C, Reguero JR, Soto MI, Domenech E, et al. (2006) Mitochondrial DNA haplogroups in Spanish patients with hypertrophic cardiomyopathy. Int J Cardiol 112: 202-206.
    • (2006) Int J Cardiol , vol.112 , pp. 202-206
    • Castro, M.G.1    Huerta, C.2    Reguero, J.R.3    Soto, M.I.4    Domenech, E.5
  • 10
    • 29144452191 scopus 로고    scopus 로고
    • Mitochondrial haplogroups and peripheral neuropathy during antiretroviral therapy: an adult AIDS clinical trials group study
    • Hulgan T, Haas DW, Haines JL, Ritchie MD, Robbins GK, et al. (2005) Mitochondrial haplogroups and peripheral neuropathy during antiretroviral therapy: an adult AIDS clinical trials group study. Aids 19: 1341-1349.
    • (2005) Aids , vol.19 , pp. 1341-1349
    • Hulgan, T.1    Haas, D.W.2    Haines, J.L.3    Ritchie, M.D.4    Robbins, G.K.5
  • 11
    • 84856899157 scopus 로고    scopus 로고
    • Mitochondrial haplogroups and control region polymorphisms in age-related macular degeneration: a case-control study
    • Mueller EE, Schaier E, Brunner SM, Eder W, Mayr JA, et al. (2012) Mitochondrial haplogroups and control region polymorphisms in age-related macular degeneration: a case-control study. PLoS ONE 7: e30874.
    • (2012) PLoS ONE , vol.7
    • Mueller, E.E.1    Schaier, E.2    Brunner, S.M.3    Eder, W.4    Mayr, J.A.5
  • 12
    • 65749119166 scopus 로고    scopus 로고
    • Mitochondrial DNA haplogroup T is associated with coronary artery disease and diabetic retinopathy: a case control study
    • Kofler B, Mueller EE, Eder W, Stanger O, Maier R, et al. (2009) Mitochondrial DNA haplogroup T is associated with coronary artery disease and diabetic retinopathy: a case control study. BMC Med Genet 10: 35.
    • (2009) BMC Med Genet , vol.10 , pp. 35
    • Kofler, B.1    Mueller, E.E.2    Eder, W.3    Stanger, O.4    Maier, R.5
  • 13
    • 47749106479 scopus 로고    scopus 로고
    • Mitochondrial DNA polymorphism A4917G is independently associated with age-related macular degeneration
    • Canter JA, Olson LM, Spencer K, Schnetz-Boutaud N, Anderson B, et al. (2008) Mitochondrial DNA polymorphism A4917G is independently associated with age-related macular degeneration. PLoS One 3: e2091.
    • (2008) PLoS One , vol.3
    • Canter, J.A.1    Olson, L.M.2    Spencer, K.3    Schnetz-Boutaud, N.4    Anderson, B.5
  • 14
    • 65749108269 scopus 로고    scopus 로고
    • Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration
    • SanGiovanni JP, Arking DE, Iyengar SK, Elashoff M, Clemons TE, et al. (2009) Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration. PLoS One 4: e5508.
    • (2009) PLoS One , vol.4
    • SanGiovanni, J.P.1    Arking, D.E.2    Iyengar, S.K.3    Elashoff, M.4    Clemons, T.E.5
  • 15
    • 33744456730 scopus 로고    scopus 로고
    • The European-specific mitochondrial cluster J/T could confer an increased risk of insulin-resistance and type 2 diabetes: an analysis of the m.4216T>C and m.4917A>G variants
    • Crispim D, Canani LH, Gross JL, Tschiedel B, Souto KE, et al. (2006) The European-specific mitochondrial cluster J/T could confer an increased risk of insulin-resistance and type 2 diabetes: an analysis of the m.4216T>C and m.4917A>G variants. Ann Hum Genet 70: 488-495.
    • (2006) Ann Hum Genet , vol.70 , pp. 488-495
    • Crispim, D.1    Canani, L.H.2    Gross, J.L.3    Tschiedel, B.4    Souto, K.E.5
  • 16
    • 34548154271 scopus 로고    scopus 로고
    • Mitochondrial haplogroup T is negatively associated with the status of elite endurance athlete
    • Castro MG, Terrados N, Reguero JR, Alvarez V, Coto E, (2007) Mitochondrial haplogroup T is negatively associated with the status of elite endurance athlete. Mitochondrion 7: 354-357.
    • (2007) Mitochondrion , vol.7 , pp. 354-357
    • Castro, M.G.1    Terrados, N.2    Reguero, J.R.3    Alvarez, V.4    Coto, E.5
  • 17
    • 29144463778 scopus 로고    scopus 로고
    • Mitochondrial DNA and survival after sepsis: a prospective study
    • Baudouin SV, Saunders D, Tiangyou W, Elson JL, Poynter J, et al. (2005) Mitochondrial DNA and survival after sepsis: a prospective study. Lancet 366: 2118-2121.
    • (2005) Lancet , vol.366 , pp. 2118-2121
    • Baudouin, S.V.1    Saunders, D.2    Tiangyou, W.3    Elson, J.L.4    Poynter, J.5
  • 19
    • 0033516529 scopus 로고    scopus 로고
    • Phylogenetic analysis of the mitochondrial genome indicates significant differences between patients with Alzheimer disease and controls in a French-Canadian founder population
    • Chagnon P, Gee M, Filion M, Robitaille Y, Belouchi M, et al. (1999) Phylogenetic analysis of the mitochondrial genome indicates significant differences between patients with Alzheimer disease and controls in a French-Canadian founder population. Am J Med Genet 85: 20-30.
    • (1999) Am J Med Genet , vol.85 , pp. 20-30
    • Chagnon, P.1    Gee, M.2    Filion, M.3    Robitaille, Y.4    Belouchi, M.5
  • 22
    • 77957822416 scopus 로고    scopus 로고
    • Evidence for sub-haplogroup h5 of mitochondrial DNA as a risk factor for late onset Alzheimer's disease
    • Santoro A, Balbi V, Balducci E, Pirazzini C, Rosini F, et al. (2010) Evidence for sub-haplogroup h5 of mitochondrial DNA as a risk factor for late onset Alzheimer's disease. PLoS ONE 5: e12037.
    • (2010) PLoS ONE , vol.5
    • Santoro, A.1    Balbi, V.2    Balducci, E.3    Pirazzini, C.4    Rosini, F.5
  • 23
    • 34147150569 scopus 로고    scopus 로고
    • Transmitochondrial technology in animal cells
    • Bacman SR, Moraes CT, (2007) Transmitochondrial technology in animal cells. Methods Cell Biol 80: 503-524.
    • (2007) Methods Cell Biol , vol.80 , pp. 503-524
    • Bacman, S.R.1    Moraes, C.T.2
  • 24
    • 0029118005 scopus 로고
    • MtDNA mutations associated with Leber's hereditary optic neuropathy: studies on cytoplasmic hybrid (cybrid) cells
    • Vergani L, Martinuzzi A, Carelli V, Cortelli P, Montagna P, et al. (1995) MtDNA mutations associated with Leber's hereditary optic neuropathy: studies on cytoplasmic hybrid (cybrid) cells. Biochem Biophys Res Commun 210: 880-888.
    • (1995) Biochem Biophys Res Commun , vol.210 , pp. 880-888
    • Vergani, L.1    Martinuzzi, A.2    Carelli, V.3    Cortelli, P.4    Montagna, P.5
  • 25
    • 28444445608 scopus 로고    scopus 로고
    • Enhanced ROS production and antioxidant defenses in cybrids harbouring mutations in mtDNA
    • Vives-Bauza C, Gonzalo R, Manfredi G, Garcia-Arumi E, Andreu AL, (2006) Enhanced ROS production and antioxidant defenses in cybrids harbouring mutations in mtDNA. Neurosci Lett 391: 136-141.
    • (2006) Neurosci Lett , vol.391 , pp. 136-141
    • Vives-Bauza, C.1    Gonzalo, R.2    Manfredi, G.3    Garcia-Arumi, E.4    Andreu, A.L.5
  • 26
    • 33748087125 scopus 로고    scopus 로고
    • Identification of mitochondrial DNA polymorphisms that alter mitochondrial matrix pH and intracellular calcium dynamics
    • Kazuno AA, Munakata K, Nagai T, Shimozono S, Tanaka M, et al. (2006) Identification of mitochondrial DNA polymorphisms that alter mitochondrial matrix pH and intracellular calcium dynamics. PLoS Genet 2: e128.
    • (2006) PLoS Genet , vol.2
    • Kazuno, A.A.1    Munakata, K.2    Nagai, T.3    Shimozono, S.4    Tanaka, M.5
  • 27
    • 77955364142 scopus 로고    scopus 로고
    • Unmasking the causes of multifactorial disorders: OXPHOS differences between mitochondrial haplogroups
    • Gomez-Duran A, Pacheu-Grau D, Lopez-Gallardo E, Diez-Sanchez C, Montoya J, et al. (2010) Unmasking the causes of multifactorial disorders: OXPHOS differences between mitochondrial haplogroups. Hum Mol Genet 19: 3343-3353.
    • (2010) Hum Mol Genet , vol.19 , pp. 3343-3353
    • Gomez-Duran, A.1    Pacheu-Grau, D.2    Lopez-Gallardo, E.3    Diez-Sanchez, C.4    Montoya, J.5
  • 28
    • 33746158952 scopus 로고    scopus 로고
    • Gene expression of cytokines and cytokine receptors is modulated by the common variability of the mitochondrial DNA in cybrid cell lines
    • Bellizzi D, Cavalcante P, Taverna D, Rose G, Passarino G, et al. (2006) Gene expression of cytokines and cytokine receptors is modulated by the common variability of the mitochondrial DNA in cybrid cell lines. Genes Cells 11: 883-891.
    • (2006) Genes Cells , vol.11 , pp. 883-891
    • Bellizzi, D.1    Cavalcante, P.2    Taverna, D.3    Rose, G.4    Passarino, G.5
  • 29
    • 66149142821 scopus 로고    scopus 로고
    • Mitochondrial DNA variability modulates mRNA and intra-mitochondrial protein levels of HSP60 and HSP75: experimental evidence from cybrid lines
    • Bellizzi D, Taverna D, D'Aquila P, De Blasi S, De Benedictis G, (2009) Mitochondrial DNA variability modulates mRNA and intra-mitochondrial protein levels of HSP60 and HSP75: experimental evidence from cybrid lines. Cell Stress Chaperones 14: 265-271.
    • (2009) Cell Stress Chaperones , vol.14 , pp. 265-271
    • Bellizzi, D.1    Taverna, D.2    D'Aquila, P.3    De Blasi, S.4    De Benedictis, G.5
  • 30
    • 57049107271 scopus 로고    scopus 로고
    • Mitochondrial DNA background modulates the assembly kinetics of OXPHOS complexes in a cellular model of mitochondrial disease
    • Pello R, Martin MA, Carelli V, Nijtmans LG, Achilli A, et al. (2008) Mitochondrial DNA background modulates the assembly kinetics of OXPHOS complexes in a cellular model of mitochondrial disease. Hum Mol Genet 17: 4001-4011.
    • (2008) Hum Mol Genet , vol.17 , pp. 4001-4011
    • Pello, R.1    Martin, M.A.2    Carelli, V.3    Nijtmans, L.G.4    Achilli, A.5
  • 31
    • 84855988961 scopus 로고    scopus 로고
    • Reduction of nuclear encoded enzymes of mitochondrial energy metabolism in cells devoid of mitochondrial DNA
    • Mueller EE, Mayr JA, Zimmermann FA, Feichtinger RG, Stanger O, et al. (2012) Reduction of nuclear encoded enzymes of mitochondrial energy metabolism in cells devoid of mitochondrial DNA. Biochem Biophys Res Commun 417: 1052-1057.
    • (2012) Biochem Biophys Res Commun , vol.417 , pp. 1052-1057
    • Mueller, E.E.1    Mayr, J.A.2    Zimmermann, F.A.3    Feichtinger, R.G.4    Stanger, O.5
  • 32
    • 64049089255 scopus 로고    scopus 로고
    • Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation
    • Accessed 2012 November 19
    • van Oven M, Kayser M (2009) Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Hum Mutat 30: E386-E394. http://www.phylotree.org. Accessed 2012 November 19.
    • (2009) Hum Mutat , vol.30
    • van Oven, M.1    Kayser, M.2
  • 33
    • 33644875533 scopus 로고    scopus 로고
    • mtDB: Human Mitochondrial Genome Database, a resource for population genetics and medical sciences
    • Accessed 2012 November 19
    • Ingman M, Gyllensten U (2006) mtDB: Human Mitochondrial Genome Database, a resource for population genetics and medical sciences. Nucleic Acids Res 34: D749-751. Accessed 2012 November 19.
    • (2006) Nucleic Acids Res , vol.34 , pp. 749-751
    • Ingman, M.1    Gyllensten, U.2
  • 34
    • 0020670470 scopus 로고
    • Human mitochondrial DNA variation and evolution: analysis of nucleotide sequences from seven individuals
    • Aquadro CF, Greenberg BD, (1983) Human mitochondrial DNA variation and evolution: analysis of nucleotide sequences from seven individuals. Genetics 103: 287-312.
    • (1983) Genetics , vol.103 , pp. 287-312
    • Aquadro, C.F.1    Greenberg, B.D.2
  • 35
    • 0020527670 scopus 로고
    • Intraspecific nucleotide sequence variability surrounding the origin of replication in human mitochondrial DNA
    • Greenberg BD, Newbold JE, Sugino A, (1983) Intraspecific nucleotide sequence variability surrounding the origin of replication in human mitochondrial DNA. Gene 21: 33-49.
    • (1983) Gene , vol.21 , pp. 33-49
    • Greenberg, B.D.1    Newbold, J.E.2    Sugino, A.3
  • 36
    • 0025308462 scopus 로고
    • Intraspecific nucleotide sequence differences in the major noncoding region of human mitochondrial DNA
    • Horai S, Hayasaka K, (1990) Intraspecific nucleotide sequence differences in the major noncoding region of human mitochondrial DNA. Am J Hum Genet 46: 828-842.
    • (1990) Am J Hum Genet , vol.46 , pp. 828-842
    • Horai, S.1    Hayasaka, K.2
  • 37
    • 0026071738 scopus 로고
    • Population variation of human mtDNA control region sequences detected by enzymatic amplification and sequence-specific oligonucleotide probes
    • Stoneking M, Hedgecock D, Higuchi RG, Vigilant L, Erlich HA, (1991) Population variation of human mtDNA control region sequences detected by enzymatic amplification and sequence-specific oligonucleotide probes. Am J Hum Genet 48: 370-382.
    • (1991) Am J Hum Genet , vol.48 , pp. 370-382
    • Stoneking, M.1    Hedgecock, D.2    Higuchi, R.G.3    Vigilant, L.4    Erlich, H.A.5
  • 38
    • 0030813676 scopus 로고    scopus 로고
    • Population genetics and disease susceptibility: characterization of central European haplogroups by mtDNA gene mutations, correlation with D loop variants and association with disease
    • Hofmann S, Jaksch M, Bezold R, Mertens S, Aholt S, et al. (1997) Population genetics and disease susceptibility: characterization of central European haplogroups by mtDNA gene mutations, correlation with D loop variants and association with disease. Hum Mol Genet 6: 1835-1846.
    • (1997) Hum Mol Genet , vol.6 , pp. 1835-1846
    • Hofmann, S.1    Jaksch, M.2    Bezold, R.3    Mertens, S.4    Aholt, S.5
  • 39
    • 0029807998 scopus 로고    scopus 로고
    • High mitochondrial sequence diversity in linguistic isolates of the Alps
    • Stenico M, Nigro L, Bertorelle G, Calafell F, Capitanio M, et al. (1996) High mitochondrial sequence diversity in linguistic isolates of the Alps. Am J Hum Genet 59: 1363-1375.
    • (1996) Am J Hum Genet , vol.59 , pp. 1363-1375
    • Stenico, M.1    Nigro, L.2    Bertorelle, G.3    Calafell, F.4    Capitanio, M.5
  • 40
    • 0033581946 scopus 로고    scopus 로고
    • Deep common ancestry of indian and western-Eurasian mitochondrial DNA lineages
    • Kivisild T, Bamshad MJ, Kaldma K, Metspalu M, Metspalu E, et al. (1999) Deep common ancestry of indian and western-Eurasian mitochondrial DNA lineages. Curr Biol 9: 1331-1334.
    • (1999) Curr Biol , vol.9 , pp. 1331-1334
    • Kivisild, T.1    Bamshad, M.J.2    Kaldma, K.3    Metspalu, M.4    Metspalu, E.5
  • 42
    • 0033495657 scopus 로고    scopus 로고
    • Molecular instability of the mitochondrial haplogroup T sequences at nucleotide positions 16292 and 16296
    • Malyarchuk BA, Derenko MV, (1999) Molecular instability of the mitochondrial haplogroup T sequences at nucleotide positions 16292 and 16296. Ann Hum Genet 63: 489-497.
    • (1999) Ann Hum Genet , vol.63 , pp. 489-497
    • Malyarchuk, B.A.1    Derenko, M.V.2
  • 44
    • 0031985058 scopus 로고    scopus 로고
    • Exhaustive scanning approach to screen all the mitochondrial tRNA genes for mutations and its application to the investigation of 35 independent patients with mitochondrial disorders
    • Sternberg D, Danan C, Lombes A, Laforet P, Girodon E, et al. (1998) Exhaustive scanning approach to screen all the mitochondrial tRNA genes for mutations and its application to the investigation of 35 independent patients with mitochondrial disorders. Hum Mol Genet 7: 33-42.
    • (1998) Hum Mol Genet , vol.7 , pp. 33-42
    • Sternberg, D.1    Danan, C.2    Lombes, A.3    Laforet, P.4    Girodon, E.5
  • 46
    • 0030344906 scopus 로고    scopus 로고
    • The Crabtree effect: a new look at the old problem
    • Wojtczak L, (1996) The Crabtree effect: a new look at the old problem. Acta Biochim Pol 43: 361-368.
    • (1996) Acta Biochim Pol , vol.43 , pp. 361-368
    • Wojtczak, L.1
  • 47
    • 0037048622 scopus 로고    scopus 로고
    • Respiratory function in cybrid cell lines carrying European mtDNA haplogroups: implications for Leber's hereditary optic neuropathy
    • Carelli V, Vergani L, Bernazzi B, Zampieron C, Bucchi L, et al. (2002) Respiratory function in cybrid cell lines carrying European mtDNA haplogroups: implications for Leber's hereditary optic neuropathy. Biochim Biophys Acta 1588: 7-14.
    • (2002) Biochim Biophys Acta , vol.1588 , pp. 7-14
    • Carelli, V.1    Vergani, L.2    Bernazzi, B.3    Zampieron, C.4    Bucchi, L.5
  • 48
    • 39649122096 scopus 로고    scopus 로고
    • Experimental assessment of bioenergetic differences caused by the common European mitochondrial DNA haplogroups H and T. Gene
    • Amo T, Yadava N, Oh R, Nicholls DG, Brand MD, (2008) Experimental assessment of bioenergetic differences caused by the common European mitochondrial DNA haplogroups H and T. Gene. 411: 69-76.
    • (2008) , vol.411 , pp. 69-76
    • Amo, T.1    Yadava, N.2    Oh, R.3    Nicholls, D.G.4    Brand, M.D.5
  • 49
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O, (1956) On the origin of cancer cells. Science 123: 309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 50
    • 33750428601 scopus 로고    scopus 로고
    • Differences in reactive oxygen species production explain the phenotypes associated with common mouse mitochondrial DNA variants
    • Moreno-Loshuertos R, Acin-Perez R, Fernandez-Silva P, Movilla N, Perez-Martos A, et al. (2006) Differences in reactive oxygen species production explain the phenotypes associated with common mouse mitochondrial DNA variants. Nat Genet 38: 1261-1268.
    • (2006) Nat Genet , vol.38 , pp. 1261-1268
    • Moreno-Loshuertos, R.1    Acin-Perez, R.2    Fernandez-Silva, P.3    Movilla, N.4    Perez-Martos, A.5
  • 51
  • 52
    • 77951256226 scopus 로고    scopus 로고
    • Mitochondrial haplogroup H correlates with ATP levels and age at onset in Huntington disease
    • Arning L, Haghikia A, Taherzadeh-Fard E, Saft C, Andrich J, et al. (2010) Mitochondrial haplogroup H correlates with ATP levels and age at onset in Huntington disease. J Mol Med (Berl) 88: 431-436.
    • (2010) J Mol Med (Berl) , vol.88 , pp. 431-436
    • Arning, L.1    Haghikia, A.2    Taherzadeh-Fard, E.3    Saft, C.4    Andrich, J.5
  • 53
    • 33847176234 scopus 로고    scopus 로고
    • Mitochondrial phosphate-carrier deficiency: a novel disorder of oxidative phosphorylation
    • Mayr JA, Merkel O, Kohlwein SD, Gebhardt BR, Bohles H, et al. (2007) Mitochondrial phosphate-carrier deficiency: a novel disorder of oxidative phosphorylation. Am J Hum Genet 80: 478-484.
    • (2007) Am J Hum Genet , vol.80 , pp. 478-484
    • Mayr, J.A.1    Merkel, O.2    Kohlwein, S.D.3    Gebhardt, B.R.4    Bohles, H.5
  • 54
    • 22544462198 scopus 로고    scopus 로고
    • Rapid screening of the entire mitochondrial DNA for low-level heteroplasmic mutations
    • Meierhofer D, Mayr JA, Ebner S, Sperl W, Kofler B, (2005) Rapid screening of the entire mitochondrial DNA for low-level heteroplasmic mutations. Mitochondrion 5: 282-296.
    • (2005) Mitochondrion , vol.5 , pp. 282-296
    • Meierhofer, D.1    Mayr, J.A.2    Ebner, S.3    Sperl, W.4    Kofler, B.5
  • 55
    • 0030015691 scopus 로고    scopus 로고
    • Lethal infantile mitochondrial disease with isolated complex I deficiency in fibroblasts but with combined complex I and IV deficiencies in muscle
    • Bentlage HA, Wendel U, Schagger H, ter Laak HJ, Janssen AJ, et al. (1996) Lethal infantile mitochondrial disease with isolated complex I deficiency in fibroblasts but with combined complex I and IV deficiencies in muscle. Neurology 47: 243-248.
    • (1996) Neurology , vol.47 , pp. 243-248
    • Bentlage, H.A.1    Wendel, U.2    Schagger, H.3    ter Laak, H.J.4    Janssen, A.J.5
  • 58
    • 67449091665 scopus 로고    scopus 로고
    • Choice of DMEM, formulated with or without pyruvate, plays an important role in assessing the in vitro cytotoxicity of oxidants and prooxidant nutraceuticals
    • Babich H, Liebling EJ, Burger RF, Zuckerbraun HL, Schuck AG, (2009) Choice of DMEM, formulated with or without pyruvate, plays an important role in assessing the in vitro cytotoxicity of oxidants and prooxidant nutraceuticals. In Vitro Cell Dev Biol Anim 45: 226-233.
    • (2009) In Vitro Cell Dev Biol Anim , vol.45 , pp. 226-233
    • Babich, H.1    Liebling, E.J.2    Burger, R.F.3    Zuckerbraun, H.L.4    Schuck, A.G.5
  • 60
    • 0033856957 scopus 로고    scopus 로고
    • Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity
    • O'Brien J, Wilson I, Orton T, Pognan F, (2000) Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity. Eur J Biochem 267: 5421-5426.
    • (2000) Eur J Biochem , vol.267 , pp. 5421-5426
    • O'Brien, J.1    Wilson, I.2    Orton, T.3    Pognan, F.4


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