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Volumn 17, Issue 5, 2014, Pages 765-777

Signaling mechanisms involved in the acute effects of estradiol on 5-HT clearance

Author keywords

ER agonist; estradiol; serotonin transporter; signaling pathways; SSRI

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FLUVOXAMINE; G PROTEIN COUPLED RECEPTOR 30; METABOTROPIC RECEPTOR 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NICOTINAMIDE ADENINE DINUCLEOTIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SEROTONIN; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR; SOMATOMEDIN C RECEPTOR; 1,3,5 TRIS(4 HYDROXYPHENYL) 4 PROPYLPYRAZOLE; 2,3-BIS(4-HYDROXYPHENYL)-PROPIONITRILE; ESTROGEN; METABOTROPIC GLUTAMATE RECEPTOR TYPE 1; METABOTROPIC RECEPTOR; NITRILE; PYRAZOLE DERIVATIVE; SEROTONIN ANTAGONIST; SLC6A4 PROTEIN, RAT;

EID: 84897444582     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S146114571300165X     Document Type: Article
Times cited : (28)

References (78)
  • 1
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-Activated protein kinase kinase in vitro and in viva
    • Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR (1995) PD 098059 is a specific inhibitor of the activation of mitogen-Activated protein kinase kinase in vitro and in viva. J Biol Chem 270:27489-27494
    • (1995) J Biol Chem , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 2
    • 84860855755 scopus 로고    scopus 로고
    • Neuroprotective role of estrogens: Relationship with insulin/IGF-1 signaling
    • Alonso A, Gonzalez C (2012) Neuroprotective role of estrogens: Relationship with insulin/IGF-1 signaling. Front Biosci (Elite Ed) 1:607-619
    • (2012) Front Biosci (Elite Ed , vol.1 , pp. 607-619
    • Alonso, A.1    Gonzalez, C.2
  • 4
    • 84928272485 scopus 로고    scopus 로고
    • Developments in the field of antidepressants, where do we go now?
    • S0924-977X 13 00144-2. doi: 10.1016/j.euroneuro.2013.04.013 [Epub ahead of print].
    • Artigas F (2013) Developments in the field of antidepressants, where do we go now? Eur Neuropsychopharmacol. S0924-977X(13)00144-2. doi: 10.1016/j.euroneuro.2013.04.013 [Epub ahead of print].
    • (2013) Eur Neuropsychopharmacol
    • Artigas, F.1
  • 6
    • 58149463233 scopus 로고    scopus 로고
    • Impact of ovarian hormones on the modulation of the serotonin transporter by fluvoxamine
    • Benmansour S, Piotrowski JP, Altamirano AV, Frazer A (2009) Impact of ovarian hormones on the modulation of the serotonin transporter by fluvoxamine. Neuropsychopharmacol 34:555-564
    • (2009) Neuropsychopharmacol , vol.34 , pp. 555-564
    • Benmansour, S.1    Piotrowski, J.P.2    Altamirano, A.V.3    Frazer, A.4
  • 8
    • 24044460136 scopus 로고    scopus 로고
    • Biogenic amine neurotransmitter transporters: Just when you thought you knew them
    • Blakely RD, Defelice LJ, Galli A (2005) Biogenic amine neurotransmitter transporters: Just when you thought you knew them. Physiology (Bethesda) 20:225-231
    • (2005) Physiology (Bethesda , vol.20 , pp. 225-231
    • Blakely, R.D.1    Defelice, L.J.2    Galli, A.3
  • 9
    • 19044387715 scopus 로고    scopus 로고
    • Estradiol activates group I and II metabotropic glutamate receptor signaling, leading to opposing influences on cAMP response element-binding protein
    • Boulware MI, Weick JP, Becklund BR, Kuo SP, Groth RD, Mermelstein PG (2005) Estradiol activates group I and II metabotropic glutamate receptor signaling, leading to opposing influences on cAMP response element-binding protein. J Neurosci 25:5066-5078
    • (2005) J Neurosci , vol.25 , pp. 5066-5078
    • Boulware, M.I.1    Weick, J.P.2    Becklund, B.R.3    Kuo, S.P.4    Groth, R.D.5    Mermelstein, P.G.6
  • 10
    • 34548632861 scopus 로고    scopus 로고
    • Caveolin proteins are essential for distinct effects of membrane estrogen receptors in neurons
    • Boulware MI, Kordasiewicz H, Mermelstein PG (2007) Caveolin proteins are essential for distinct effects of membrane estrogen receptors in neurons. J Neurosci 27:9941-9950
    • (2007) J Neurosci , vol.27 , pp. 9941-9950
    • Boulware, M.I.1    Kordasiewicz, H.2    Mermelstein, P.G.3
  • 11
    • 84862305294 scopus 로고    scopus 로고
    • Signaling pathways mediating the neuroprotective effects of sex steroids and SERMs in Parkinson's disease
    • Bourque M, Dluzen DE, Di Paolo T (2012) Signaling pathways mediating the neuroprotective effects of sex steroids and SERMs in Parkinson's disease. Front Neuroendocrinol 33:169-178
    • (2012) Front Neuroendocrinol , vol.33 , pp. 169-178
    • Bourque, M.1    Dluzen, D.E.2    Di Paolo, T.3
  • 12
    • 51249114495 scopus 로고    scopus 로고
    • Estrogen regulation of glucose metabolism and mitochondrial function: Therapeutic implications for prevention of Alzheimer's disease
    • Brinton RD (2008) Estrogen regulation of glucose metabolism and mitochondrial function: Therapeutic implications for prevention of Alzheimer's disease. Adv Drug Deliv Rev 60:1504-1511
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 1504-1511
    • Brinton, R.D.1
  • 15
    • 34548436637 scopus 로고    scopus 로고
    • Membrane estrogen receptor-Alpha interactions with metabotropic glutamate receptor 1a modulate female sexual receptivity in rats
    • Dewing P, Boulware MI, Sinchak K, Christensen A, Mermelstein PG, Micevych P (2007) Membrane estrogen receptor-Alpha interactions with metabotropic glutamate receptor 1a modulate female sexual receptivity in rats. J Neurosci 27:9294-9300
    • (2007) J Neurosci , vol.27 , pp. 9294-9300
    • Dewing, P.1    Boulware, M.I.2    Sinchak, K.3    Christensen, A.4    Mermelstein, P.G.5    Micevych, P.6
  • 16
    • 0742322847 scopus 로고    scopus 로고
    • Morphological effects of estrogen on cholinergic neurons in vitro involves activation of extracellular signal-regulated kinases
    • Dominguez R, Jalali C, De Lacalle S (2004) Morphological effects of estrogen on cholinergic neurons in vitro involves activation of extracellular signal-regulated kinases. J Neurosci 24:982-990
    • (2004) J Neurosci , vol.24 , pp. 982-990
    • Dominguez, R.1    Jalali, C.2    De Lacalle, S.3
  • 17
    • 33947234229 scopus 로고    scopus 로고
    • 17-Beta-estradiol-mediated activation of extracellular-signal regulated kinase, phosphatidylinositol 3-kinase/protein kinase B-Akt and N-methyl-D-Aspartate receptor phosphorylation in cortical synaptoneurosomes
    • Dominguez R, Liu R, Baudry M (2007) 17-Beta-estradiol-mediated activation of extracellular-signal regulated kinase, phosphatidylinositol 3-kinase/protein kinase B-Akt and N-methyl-D-Aspartate receptor phosphorylation in cortical synaptoneurosomes. J Neurochem 101:232-240
    • (2007) J Neurochem , vol.101 , pp. 232-240
    • Dominguez, R.1    Liu, R.2    Baudry, M.3
  • 18
    • 33847308098 scopus 로고    scopus 로고
    • A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment
    • Duman CH, Schlesinger L, Kodama M, Russell DS, Duman RS (2007) A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment. Biol Psychiatry 61:661-670
    • (2007) Biol Psychiatry , vol.61 , pp. 661-670
    • Duman, C.H.1    Schlesinger, L.2    Kodama, M.3    Russell, D.S.4    Duman, R.S.5
  • 19
    • 84872320031 scopus 로고    scopus 로고
    • Depression and treatment response: Dynamic interplay of signaling pathways and altered neural processes
    • Duric V, Duman RS (2013) Depression and treatment response: Dynamic interplay of signaling pathways and altered neural processes. Cell Mol Life Sci 70:39-53
    • (2013) Cell Mol Life Sci , vol.70 , pp. 39-53
    • Duric, V.1    Duman, R.S.2
  • 20
    • 0035020808 scopus 로고    scopus 로고
    • Reduced activation and expression of ERK1/2 MAP kinase in the post-mortem brain of depressed suicide subjects
    • Dwivedi Y, Rizavi HS, Roberts RC, Conley RC, Tamminga CA, Pandey GN (2001) Reduced activation and expression of ERK1/2 MAP kinase in the post-mortem brain of depressed suicide subjects. J Neurochem 77:916-928
    • (2001) J Neurochem , vol.77 , pp. 916-928
    • Dwivedi, Y.1    Rizavi, H.S.2    Roberts, R.C.3    Conley, R.C.4    Tamminga, C.A.5    Pandey, G.N.6
  • 22
    • 0034842003 scopus 로고    scopus 로고
    • Mechanisms of ovarian steroid regulation of norepinephrine receptor-mediated signal transduction in the hypothalamus: Implications for female reproductive physiology
    • Etgen AM, Ansonoff MA, Quesada A (2001) Mechanisms of ovarian steroid regulation of norepinephrine receptor-mediated signal transduction in the hypothalamus: Implications for female reproductive physiology. Horm Behav 40:169-177
    • (2001) Horm Behav , vol.40 , pp. 169-177
    • Etgen, A.M.1    Ansonoff, M.A.2    Quesada, A.3
  • 24
    • 84875154348 scopus 로고    scopus 로고
    • Estradiol-induced object recognition memory consolidation is dependent on activation of mTOR signaling in the dorsal hippocampus
    • Fortress AM, Fan L, Orr PT, Zhao Z, Frick KM (2013) Estradiol-induced object recognition memory consolidation is dependent on activation of mTOR signaling in the dorsal hippocampus. Learn Mem 20:147-155
    • (2013) Learn Mem , vol.20 , pp. 147-155
    • Fortress, A.M.1    Fan, L.2    Orr, P.T.3    Zhao, Z.4    Frick, K.M.5
  • 25
    • 84860441405 scopus 로고    scopus 로고
    • Vagal nerve stimulation rapidly activates brain-derived neurotrophic factor receptor TrkB in rat brain
    • doi:10.1371/journal. pone.0034844
    • Furmaga H, Carreno FR, Frazer A (2012) Vagal nerve stimulation rapidly activates brain-derived neurotrophic factor receptor TrkB in rat brain. PLoS ONE 7:e34844. doi:10.1371/journal. pone.0034844
    • (2012) PLoS ONE , vol.7
    • Furmaga, H.1    Carreno, F.R.2    Frazer, A.3
  • 26
    • 77955496323 scopus 로고    scopus 로고
    • Interactions of estradiol and insulin-like growth factor-I signalling in the nervous system: New advances
    • Garcia-Segura LM, Arévalo MA, Azcoitia I (2010) Interactions of estradiol and insulin-like growth factor-I signalling in the nervous system: New advances. Prog Brain Res 181:251-272
    • (2010) Prog Brain Res , vol.181 , pp. 251-272
    • Garcia-Segura, L.M.1    Arévalo, M.A.2    Azcoitia, I.3
  • 27
    • 77957161470 scopus 로고    scopus 로고
    • Membrane estrogen receptors activate the metabotropic glutamate receptors mGluR5 and mGluR3 to bidirectionally regulate CREB phosphorylation in female rat striatal neurons
    • Grove-Strawser D, Boulware MI, Mermelstein PG (2010) Membrane estrogen receptors activate the metabotropic glutamate receptors mGluR5 and mGluR3 to bidirectionally regulate CREB phosphorylation in female rat striatal neurons. Neuroscience 170:1045-1055
    • (2010) Neuroscience , vol.170 , pp. 1045-1055
    • Grove-Strawser, D.1    Boulware, M.I.2    Mermelstein, P.G.3
  • 29
    • 0035910350 scopus 로고    scopus 로고
    • Estrogen stimulates the mitogen-Activated protein kinase pathway in midbrain astroglia
    • Ivanova T, Karolczak M, Beyer C (2001) Estrogen stimulates the mitogen-Activated protein kinase pathway in midbrain astroglia. Brain Res 889:264-269
    • (2001) Brain Res , vol.889 , pp. 264-269
    • Ivanova, T.1    Karolczak, M.2    Beyer, C.3
  • 30
    • 33847062554 scopus 로고    scopus 로고
    • MAPK signaling is critical to estradiol protection of CA1 neurons in global ischemia
    • Jover-Mengual T, Zukin RS, Etgen AM (2007) MAPK signaling is critical to estradiol protection of CA1 neurons in global ischemia. Endocrinology 148:1131-1143
    • (2007) Endocrinology , vol.148 , pp. 1131-1143
    • Jover-Mengual, T.1    Zukin, R.S.2    Etgen, A.M.3
  • 32
    • 33846095133 scopus 로고    scopus 로고
    • Alteration in kinase activity but not in protein levels of protein kinase B and glycogen synthase kinase-3beta in ventral prefrontal cortex of depressed suicide victims
    • Karege F, Perroud N, Burkhardt S, Schwald M, Ballmann E, La Harpe R, Malafosse A (2007) Alteration in kinase activity but not in protein levels of protein kinase B and glycogen synthase kinase-3beta in ventral prefrontal cortex of depressed suicide victims. Biol Psychiatry 61:240-245
    • (2007) Biol Psychiatry , vol.61 , pp. 240-245
    • Karege, F.1    Perroud, N.2    Burkhardt, S.3    Schwald, M.4    Ballmann, E.5    La Harpe, R.6    Malafosse, A.7
  • 33
    • 0742287855 scopus 로고    scopus 로고
    • Proteomic analysis of protein changes developing in rat hippocampus after chronic antidepressant treatment: Implications for depressive disorders and future therapies
    • Khawaja X, Xu J, Liang JJ, Barrett JE (2004) Proteomic analysis of protein changes developing in rat hippocampus after chronic antidepressant treatment: Implications for depressive disorders and future therapies. J Neurosci Res 75:451-460
    • (2004) J Neurosci Res , vol.75 , pp. 451-460
    • Khawaja, X.1    Xu, J.2    Liang, J.J.3    Barrett, J.E.4
  • 34
    • 77957345404 scopus 로고    scopus 로고
    • Membrane estrogen receptors stimulate intracellular calcium release and progesterone synthesis in hypothalamic astrocytes
    • Kuo J, Hamid N, Bondar G, Prossnitz ER, Micevych P (2010) Membrane estrogen receptors stimulate intracellular calcium release and progesterone synthesis in hypothalamic astrocytes. J Neurosci 30:12950-12957
    • (2010) J Neurosci , vol.30 , pp. 12950-12957
    • Kuo, J.1    Hamid, N.2    Bondar, G.3    Prossnitz, E.R.4    Micevych, P.5
  • 35
    • 0035136594 scopus 로고    scopus 로고
    • Neuroprotection by estrogen via extracellular signal-regulated kinase against quinolinic acid-induced cell death in the rat hippocampus
    • Kuroki Y, Fukushima K, Kanda Y, Mizuno K, Watanabe Y (2001) Neuroprotection by estrogen via extracellular signal-regulated kinase against quinolinic acid-induced cell death in the rat hippocampus. Eur J Neurosci 13:472-476
    • (2001) Eur J Neurosci , vol.13 , pp. 472-476
    • Kuroki, Y.1    Fukushima, K.2    Kanda, Y.3    Mizuno, K.4    Watanabe, Y.5
  • 36
    • 63649135792 scopus 로고    scopus 로고
    • Estradiol rescues neurons from global ischemia-induced cell death: Multiple cellular pathways of neuroprotection
    • Lebesgue D, Chevaleyre V, Zukin RS, Etgen AM (2009) Estradiol rescues neurons from global ischemia-induced cell death: Multiple cellular pathways of neuroprotection. Steroids 74:555-561
    • (2009) Steroids , vol.74 , pp. 555-561
    • Lebesgue, D.1    Chevaleyre, V.2    Zukin, R.S.3    Etgen, A.M.4
  • 37
    • 0033230631 scopus 로고    scopus 로고
    • Cellular functions of the plasma membrane estrogen receptor
    • Levin ER (1999) Cellular functions of the plasma membrane estrogen receptor. Trends Endocrinol Metab 10:374-377
    • (1999) Trends Endocrinol Metab , vol.10 , pp. 374-377
    • Levin, E.R.1
  • 38
    • 34447134271 scopus 로고    scopus 로고
    • Increasing the levels of insulin-like growth factor-I by an IGF binding protein inhibitor produces anxiolytic and antidepressant-like effects
    • Malberg JE, Platt B, Rizzo SJ, Ring RH, Lucki I, Schechter LE, Rosenzweig-Lipson S (2007) Increasing the levels of insulin-like growth factor-I by an IGF binding protein inhibitor produces anxiolytic and antidepressant-like effects. Neuropsychopharmacol 32:2360-2368
    • (2007) Neuropsychopharmacol , vol.32 , pp. 2360-2368
    • Malberg, J.E.1    Platt, B.2    Rizzo, S.J.3    Ring, R.H.4    Lucki, I.5    Schechter, L.E.6    Rosenzweig-Lipson, S.7
  • 39
    • 33645390589 scopus 로고    scopus 로고
    • S-palmitoylation modulates estrogen receptor alpha localization and functions
    • Marino M, Ascenzi P, Acconcia F (2006) S-palmitoylation modulates estrogen receptor alpha localization and functions. Steroids 71:298-303
    • (2006) Steroids , vol.71 , pp. 298-303
    • Marino, M.1    Ascenzi, P.2    Acconcia, F.3
  • 40
    • 80555135802 scopus 로고    scopus 로고
    • Estrogen receptors stimulate brain region specific metabotropic glutamate receptors to rapidly initiate signal transduction pathways
    • Meitzen J, Mermelstein PG (2011) Estrogen receptors stimulate brain region specific metabotropic glutamate receptors to rapidly initiate signal transduction pathways. J Chem Neuroanat 4:236-241
    • (2011) J Chem Neuroanat , vol.4 , pp. 236-241
    • Meitzen, J.1    Mermelstein, P.G.2
  • 41
    • 0037430850 scopus 로고    scopus 로고
    • Estrogen receptor alpha forms estrogen-dependent multimolecular complexes with insulin-like growth factor receptor and phosphatidylinositol 3-kinase in the adult rat brain
    • Mendez P, Azcoitia I, Garcia-Segura LM (2003) Estrogen receptor alpha forms estrogen-dependent multimolecular complexes with insulin-like growth factor receptor and phosphatidylinositol 3-kinase in the adult rat brain. Brain Res Mol Brain Res 112:170-176
    • (2003) Brain Res Mol Brain Res , vol.112 , pp. 170-176
    • Mendez, P.1    Azcoitia, I.2    Garcia-Segura, L.M.3
  • 42
    • 17844399257 scopus 로고    scopus 로고
    • Interdependence of oestrogen and insulin-like growth factor-I in the brain: Potential for analysing neuroprotective mechanisms
    • Mendez P, Azcoitia I, Garcia-Segura LM (2005) Interdependence of oestrogen and insulin-like growth factor-I in the brain: Potential for analysing neuroprotective mechanisms. J Endocrinol 185:11-17
    • (2005) J Endocrinol , vol.185 , pp. 11-17
    • Mendez, P.1    Azcoitia, I.2    Garcia-Segura, L.M.3
  • 44
    • 53749104246 scopus 로고    scopus 로고
    • Membrane estrogen receptors acting through metabotropic glutamate receptors: An emerging mechanism of estrogen action in brain
    • Micevych PE, Mermelstein PG (2008) Membrane estrogen receptors acting through metabotropic glutamate receptors: An emerging mechanism of estrogen action in brain. Mol Neurobiol 38:66-77
    • (2008) Mol Neurobiol , vol.38 , pp. 66-77
    • Micevych, P.E.1    Mermelstein, P.G.2
  • 45
    • 0035206637 scopus 로고    scopus 로고
    • Estradiol (E2 elicits SRC phosphorylation in the mouse neocortex: The initial event in E2 activation of the MAPK cascade?
    • Nethrapalli IS, Singh M, Guan X, Guo Q, Lubahn DB, Korach KS, Toran-Allerand CD (2001) Estradiol (E2) elicits SRC phosphorylation in the mouse neocortex: The initial event in E2 activation of the MAPK cascade? Endocrinology 142:5145-5148
    • (2001) Endocrinology , vol.142 , pp. 5145-5148
    • Nethrapalli, I.S.1    Singh, M.2    Guan, X.3    Guo, Q.4    Lubahn, D.B.5    Korach, K.S.6    Toran-Allerand, C.D.7
  • 47
    • 0026483202 scopus 로고
    • Inhibition of cellular proliferation by peptide analogues of insulin-like growth factor
    • Pietrzkowski Z, Wernicke D, Porcu P, Jameson BA, Baserga R (1992) Inhibition of cellular proliferation by peptide analogues of insulin-like growth factor. Cancer Res 52:6447-6451
    • (1992) Cancer Res , vol.52 , pp. 6447-6451
    • Pietrzkowski, Z.1    Wernicke, D.2    Porcu, P.3    Jameson, B.A.4    Baserga, R.5
  • 48
    • 84856858645 scopus 로고    scopus 로고
    • Glycogen synthase Kinase-3 is an intermediate modulator of serotonin neurotransmission
    • Polter AM, Li X (2011) Glycogen synthase Kinase-3 is an intermediate modulator of serotonin neurotransmission. Front Mol Neurosci 4:31
    • (2011) Front Mol Neurosci , vol.4 , pp. 31
    • Polter, A.M.1    Li, X.2
  • 49
    • 0031014266 scopus 로고    scopus 로고
    • Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression
    • Qian Y, Galli A, Ramamoorthy S, Risso S, DeFelice LJ, Blakely RD (1997) Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression. J Neurosci 17:45-57
    • (1997) J Neurosci , vol.17 , pp. 45-57
    • Qian, Y.1    Galli, A.2    Ramamoorthy, S.3    Risso, S.4    DeFelice, L.J.5    Blakely, R.D.6
  • 50
    • 0037088934 scopus 로고    scopus 로고
    • Functional interactions between estrogen and insulin-like growth factor-I in the regulation of alpha 1B-Adrenoceptors and female reproductive function
    • Quesada A, Etgen AM (2002) Functional interactions between estrogen and insulin-like growth factor-I in the regulation of alpha 1B-Adrenoceptors and female reproductive function. J Neurosci 22:2401-2408
    • (2002) J Neurosci , vol.22 , pp. 2401-2408
    • Quesada, A.1    Etgen, A.M.2
  • 51
    • 0347629016 scopus 로고    scopus 로고
    • Estrogen interacts with the IGF-1 system to protect nigrostriatal dopamine and maintain motoric behavior after 6-hydroxdopamine lesions
    • Quesada A, Micevych PE (2004) Estrogen interacts with the IGF-1 system to protect nigrostriatal dopamine and maintain motoric behavior after 6-hydroxdopamine lesions. J Neurosci Res 75:107-116
    • (2004) J Neurosci Res , vol.75 , pp. 107-116
    • Quesada, A.1    Micevych, P.E.2
  • 52
    • 41549156954 scopus 로고    scopus 로고
    • PI3 kinase/Akt activation mediates estrogen and IGF-1 nigral DA neuronal neuroprotection against a unilateral rat model of Parkinson's disease
    • Quesada A, Lee BY, Micevych PE (2008) PI3 kinase/Akt activation mediates estrogen and IGF-1 nigral DA neuronal neuroprotection against a unilateral rat model of Parkinson's disease. Dev Neurobiol 68:632-644
    • (2008) Dev Neurobiol , vol.68 , pp. 632-644
    • Quesada, A.1    Lee, B.Y.2    Micevych, P.E.3
  • 53
    • 0033618638 scopus 로고    scopus 로고
    • Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants
    • Ramamoorthy S, Blakely RD (1999) Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants. Science 285:763-736
    • (1999) Science , vol.285 , pp. 763-736
    • Ramamoorthy, S.1    Blakely, R.D.2
  • 54
    • 0031708019 scopus 로고    scopus 로고
    • Biosyn thesis N-glycosylation, and surface trafficking of biogenic amine transporter proteins
    • Ramamoorthy S, Melikian HE, Qian Y, Blakely RD (1998) Biosynthesis, N-glycosylation, and surface trafficking of biogenic amine transporter proteins. Methods Enzymol 296:347-370
    • (1998) Methods Enzymol , vol.296 , pp. 347-370
    • Ramamoorthy, S.1    Melikian, H.E.2    Qian, Y.3    Blakely, R.D.4
  • 55
    • 79151476913 scopus 로고    scopus 로고
    • Regulation of monoamine transporters: Role of transporter phosphorylation
    • Ramamoorthy S, Shippenberg TS, Jayanthi LD (2011) Regulation of monoamine transporters: Role of transporter phosphorylation. Pharmacol Ther 129:220-238
    • (2011) Pharmacol Ther , vol.129 , pp. 220-238
    • Ramamoorthy, S.1    Shippenberg, T.S.2    Jayanthi, L.D.3
  • 56
    • 34447121927 scopus 로고    scopus 로고
    • Pharmacologically diverse antidepressants rapidly activate brain-derived neurotrophic factor receptor TrkB and induce Phospholipase-Cgamma signaling pathways in mouse brain
    • Rantamaki T, Hendolin P, Kankaanpaa A, Mijatovic J, Piepponen P, Domenici E, Chao MV, Männistö PT, Castrén E (2007) Pharmacologically diverse antidepressants rapidly activate brain-derived neurotrophic factor receptor TrkB and induce Phospholipase-Cgamma signaling pathways in mouse brain. Neuropsychopharmacol 32:2152-2162
    • (2007) Neuropsychopharmacol , vol.32 , pp. 2152-2162
    • Rantamaki, T.1    Hendolin, P.2    Kankaanpaa, A.3    Mijatovic, J.4    Piepponen, P.5    Domenici, E.6    Chao, M.V.7    Männistö, P.T.8    Castrén, E.9
  • 59
    • 12144279565 scopus 로고    scopus 로고
    • A role for p38 mitogen-Activated protein kinase in the regulation of the serotonin transporter: Evidence for distinct cellular mechanisms involved in transporter surface expression
    • Samuvel DJ, Jayanthi LD, Bhat NR, Ramamoorthy S (2005) A role for p38 mitogen-Activated protein kinase in the regulation of the serotonin transporter: Evidence for distinct cellular mechanisms involved in transporter surface expression. J Neurosci 25:29-41
    • (2005) J Neurosci , vol.25 , pp. 29-41
    • Samuvel, D.J.1    Jayanthi, L.D.2    Bhat, N.R.3    Ramamoorthy, S.4
  • 60
    • 0027939430 scopus 로고
    • Role of phosphatidylinositol-3-kinase in insulin receptor signaling: Studies with inhibitor LY294002
    • Sanchez-Margálet V, Goldfine ID, Vlahos CJ, Sung CK (1994) Role of phosphatidylinositol-3-kinase in insulin receptor signaling: Studies with inhibitor, LY294002. Biochem Biophys Res Commun 204:446-452
    • (1994) Biochem Biophys Res Commun , vol.204 , pp. 446-452
    • Sanchez-Margálet, V.1    Goldfine, I.D.2    Vlahos, C.J.3    Sung, C.K.4
  • 61
    • 0036580702 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-Term potentiation in the hippocampal CA1 region
    • Sanna PP, Cammalleri M, Berton F, Simpson C, Lutjens R, Bloom FE, Francesconi W (2002) Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-Term potentiation in the hippocampal CA1 region. J Neurosci 22:3359-3365
    • (2002) J Neurosci , vol.22 , pp. 3359-3365
    • Sanna, P.P.1    Cammalleri, M.2    Berton, F.3    Simpson, C.4    Lutjens, R.5    Bloom, F.E.6    Francesconi, W.7
  • 62
    • 13144257746 scopus 로고    scopus 로고
    • Similarities between actions of estrogen and BDNF in the hippocampus: Coincidence or clue?
    • Scharfman HE, Maclusky NJ (2005) Similarities between actions of estrogen and BDNF in the hippocampus: Coincidence or clue? Trends Neurosci 2:79-85
    • (2005) Trends Neurosci , vol.2 , pp. 79-85
    • Scharfman, H.E.1    Maclusky, N.J.2
  • 63
    • 33750951890 scopus 로고    scopus 로고
    • Estrogen and brain-derived neurotrophic factor (BDNF) in hippocampus: Complexity of steroid hormone-growth factor interactions in the adult CNS
    • Scharfman HE, MacLusky NJ (2006) Estrogen and brain-derived neurotrophic factor (BDNF) in hippocampus: Complexity of steroid hormone-growth factor interactions in the adult CNS. Front Neuroendocrinol 27:415-435
    • (2006) Front Neuroendocrinol , vol.27 , pp. 415-435
    • Scharfman, H.E.1    MacLusky, N.J.2
  • 64
    • 34548395111 scopus 로고    scopus 로고
    • The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior
    • Schmidt HD, Duman RS (2007) The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior. Behav Pharmacol 18:391-418
    • (2007) Behav Pharmacol , vol.18 , pp. 391-418
    • Schmidt, H.D.1    Duman, R.S.2
  • 65
    • 77952626873 scopus 로고    scopus 로고
    • The neurotoxic effects of estrogen on ischemic stroke in older female rats is associated with age-dependent loss of insulin-like growth factor-1
    • Selvamani A, Sohrabji F (2010) The neurotoxic effects of estrogen on ischemic stroke in older female rats is associated with age-dependent loss of insulin-like growth factor-1. J Neurosci 30:6852-6861
    • (2010) J Neurosci , vol.30 , pp. 6852-6861
    • Selvamani, A.1    Sohrabji, F.2
  • 66
    • 0036135006 scopus 로고    scopus 로고
    • Estradiol-induced phosphorylation of ERK1/2 in explants of the mouse cerebral cortex: The roles of heat shock protein 90 (Hsp90) and MEK2
    • Sétáló G Jr., Singh M, Guan X, Toran-Allerand CD (2002) Estradiol-induced phosphorylation of ERK1/2 in explants of the mouse cerebral cortex: The roles of heat shock protein 90 (Hsp90) and MEK2. J Neurobiol 50:1-12
    • (2002) J Neurobiol , vol.50 , pp. 1-12
    • Sétáló Jr., G.1    Singh, M.2    Guan, X.3    Toran-Allerand, C.D.4
  • 67
    • 0034727094 scopus 로고    scopus 로고
    • Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
    • Simoncini T, Hafezi-Moghadam A, Brazil DP, Ley K, Chin WW, Liao JK (2000) Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature 407:538-541
    • (2000) Nature , vol.407 , pp. 538-541
    • Simoncini, T.1    Hafezi-Moghadam, A.2    Brazil, D.P.3    Ley, K.4    Chin, W.W.5    Liao, J.K.6
  • 68
    • 0342803689 scopus 로고    scopus 로고
    • Estrogen-induced activation of the mitogen-Activated protein kinase cascade in the cerebral cortex of estrogen receptor-Alpha knock-out mice
    • Singh M, Sétáló G Jr., Guan X, Frail DE, Toran-Allerand CD (2000) Estrogen-induced activation of the mitogen-Activated protein kinase cascade in the cerebral cortex of estrogen receptor-Alpha knock-out mice. J Neurosci 20:1694-1700
    • (2000) J Neurosci , vol.20 , pp. 1694-1700
    • Singh, M.1    Sétáló Jr., G.2    Guan, X.3    Frail, D.E.4    Toran-Allerand, C.D.5
  • 69
    • 84856231207 scopus 로고    scopus 로고
    • Estradiol acts via estrogen receptors alpha and beta on pathways important for synaptic plasticity in the mouse hippocampal formation
    • Spencer-Segal JL, Tsuda MC, Mattei L, Waters EM, Romeo RD, Milner TA, McEwen BS, Ogawa S (2012) Estradiol acts via estrogen receptors alpha and beta on pathways important for synaptic plasticity in the mouse hippocampal formation. Neuroscience 202:131-146
    • (2012) Neuroscience , vol.202 , pp. 131-146
    • Spencer-Segal, J.L.1    Tsuda, M.C.2    Mattei, L.3    Waters, E.M.4    Romeo, R.D.5    Milner, T.A.6    McEwen, B.S.7    Ogawa, S.8
  • 70
    • 49749085174 scopus 로고    scopus 로고
    • Going with the flow: Trafficking-dependent and-independent regulation of serotonin transport
    • Steiner JA, Carneiro AM, Blakely RD (2008) Going with the flow: Trafficking-dependent and-independent regulation of serotonin transport. Traffic 9:1393-1402
    • (2008) Traffic , vol.9 , pp. 1393-1402
    • Steiner, J.A.1    Carneiro, A.M.2    Blakely, R.D.3
  • 71
    • 0028334738 scopus 로고
    • A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits
    • Stephens L, Smrcka A, Cooke FT, Jackson TR, Sternweis PC, Hawkins PT (1994) A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits. Cell 77:83-93
    • (1994) Cell , vol.77 , pp. 83-93
    • Stephens, L.1    Smrcka, A.2    Cooke, F.T.3    Jackson, T.R.4    Sternweis, P.C.5    Hawkins, P.T.6
  • 72
    • 53549099115 scopus 로고    scopus 로고
    • Role of the phosphoinositide 3-kinase-Akt-mammalian target of the rapamycin signaling pathway in long-Term potentiation and trace fear conditioning memory in rat medial prefrontal cortex
    • Sui L, Wang J, Li BM (2008) Role of the phosphoinositide 3-kinase-Akt-mammalian target of the rapamycin signaling pathway in long-Term potentiation and trace fear conditioning memory in rat medial prefrontal cortex. Learn Mem 15:762-776
    • (2008) Learn Mem , vol.15 , pp. 762-776
    • Sui, L.1    Wang, J.2    Li, B.M.3
  • 73
    • 35649009890 scopus 로고    scopus 로고
    • Intracellular signaling pathways pave roads to recovery for mood disorders
    • Tanis KQ, Duman RS (2007) Intracellular signaling pathways pave roads to recovery for mood disorders. Ann Med 39:531-544
    • (2007) Ann Med , vol.39 , pp. 531-544
    • Tanis, K.Q.1    Duman, R.S.2
  • 74
    • 0032907868 scopus 로고    scopus 로고
    • Novel mechanisms of estrogen action in the brain: New players in an old story
    • Toran-Allerand CD, Singh M, Sétáló G Jr (1999) Novel mechanisms of estrogen action in the brain: New players in an old story. Front Neuroendocrinol. 20:97-121
    • (1999) Front Neuroendocrinol , vol.20 , pp. 97-121
    • Toran-Allerand, C.D.1    Singh, M.2    Sétáló Jr., G.3
  • 75
    • 0037373414 scopus 로고    scopus 로고
    • Estrogen activation of cyclic adenosine 5'-monophosphate response element-mediated transcription requires the extracellularly regulated kinase/ mitogen-Activated protein kinase pathway
    • Wade CB, Dorsa DM (2003) Estrogen activation of cyclic adenosine 5'-monophosphate response element-mediated transcription requires the extracellularly regulated kinase/ mitogen-Activated protein kinase pathway. Endocrinology 144:832-838
    • (2003) Endocrinology , vol.144 , pp. 832-838
    • Wade, C.B.1    Dorsa, D.M.2
  • 76
    • 0037097439 scopus 로고    scopus 로고
    • Estradiol enhances Akt activation in cortical explant cultures following neuronal injury
    • Wilson ME, Liu Y, Wise PM (2002) Estradiol enhances Akt activation in cortical explant cultures following neuronal injury. Brain Res Mol Brain Res 102:48-54
    • (2002) Brain Res Mol Brain Res , vol.102 , pp. 48-54
    • Wilson, M.E.1    Liu, Y.2    Wise, P.M.3
  • 78
    • 18144373742 scopus 로고    scopus 로고
    • P38 MAPK activation elevates serotonin transport activity via a trafficking-independent, protein phosphatase 2A-dependent process
    • Zhu CB, Carneiro AM, Dostmann WR, Hewlett WA, Blakely RD (2005) p38 MAPK activation elevates serotonin transport activity via a trafficking-independent, protein phosphatase 2A-dependent process. J Biol Chem 280:15649-15658
    • (2005) J Biol Chem , vol.280 , pp. 15649-15658
    • Zhu, C.B.1    Carneiro, A.M.2    Dostmann, W.R.3    Hewlett, W.A.4    Blakely, R.D.5


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