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Volumn 267, Issue , 2014, Pages 55-65

Dipeptidyl peptidase-4 inhibition by Pterocarpus marsupium and Eugenia jambolana ameliorates streptozotocin induced Alzheimer's disease

Author keywords

Amyloid load; Eugenia jambolana; Glucagon like peptide 1; Neuro inflammation; Pterocarpus marsupium; Tau phosphorylation

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; DIPEPTIDYL PEPTIDASE IV; GLUCAGON LIKE PEPTIDE 1; KINO EXTRACT; PLANT EXTRACT; STREPTOZOCIN; SYZYGIUM CUMINI EXTRACT; TAU PROTEIN; UNCLASSIFIED DRUG; VILDAGLIPTIN; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); DIPEPTIDYL PEPTIDASE IV INHIBITOR; MAPT PROTEIN, RAT; NEUROPROTECTIVE AGENT; PEPTIDE FRAGMENT; PLANT MEDICINAL PRODUCT;

EID: 84897429031     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2014.03.026     Document Type: Article
Times cited : (42)

References (46)
  • 2
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
    • Hardy J., Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002, 297:353-356.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 3
    • 0345872128 scopus 로고    scopus 로고
    • Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial
    • Tariot P.N., Farlow M.R., Grossberg G.T., Graham S.M., McDonald S., Gergel I. Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial. J Am Med Assoc 2004, 291:317-324.
    • (2004) J Am Med Assoc , vol.291 , pp. 317-324
    • Tariot, P.N.1    Farlow, M.R.2    Grossberg, G.T.3    Graham, S.M.4    McDonald, S.5    Gergel, I.6
  • 5
    • 0035142278 scopus 로고    scopus 로고
    • Cholinesterase inhibitors for Alzheimer's disease
    • Grutzendler J., Morris J.C. Cholinesterase inhibitors for Alzheimer's disease. Drugs 2001, 61:41-52.
    • (2001) Drugs , vol.61 , pp. 41-52
    • Grutzendler, J.1    Morris, J.C.2
  • 6
    • 84891766932 scopus 로고    scopus 로고
    • A molecular connection of Pterocarpus marsupium, Eugenia jambolana and Gymnema sylvestre with dipeptidyl peptidase-4 in the treatment of diabetes
    • Kosaraju J., Dubala A., Chinni S., Khatwal R.B., Satish Kumar M.N., Basavan D. A molecular connection of Pterocarpus marsupium, Eugenia jambolana and Gymnema sylvestre with dipeptidyl peptidase-4 in the treatment of diabetes. Pharm Biol 2014, 52:268-271.
    • (2014) Pharm Biol , vol.52 , pp. 268-271
    • Kosaraju, J.1    Dubala, A.2    Chinni, S.3    Khatwal, R.B.4    Satish Kumar, M.N.5    Basavan, D.6
  • 7
    • 84884829726 scopus 로고    scopus 로고
    • Saxagliptin: a dipeptidyl peptidase-4 inhibitor ameliorates streptozotocin induced Alzheimer's disease
    • Kosaraju J., Gali C.C., Khatwal R.B., Dubala A., Chinni S., Holsinger R.M., et al. Saxagliptin: a dipeptidyl peptidase-4 inhibitor ameliorates streptozotocin induced Alzheimer's disease. Neuropharmacology 2013, 72:291-300.
    • (2013) Neuropharmacology , vol.72 , pp. 291-300
    • Kosaraju, J.1    Gali, C.C.2    Khatwal, R.B.3    Dubala, A.4    Chinni, S.5    Holsinger, R.M.6
  • 8
    • 84888008405 scopus 로고    scopus 로고
    • Vildagliptin: an anti-diabetes agent ameliorates cognitive deficits and pathology observed in streptozotocin-induced Alzheimer's disease
    • Kosaraju J., Murthy V., Khatwal R.B., Dubala A., Chinni S., Muthureddy Nataraj S.K., et al. Vildagliptin: an anti-diabetes agent ameliorates cognitive deficits and pathology observed in streptozotocin-induced Alzheimer's disease. J Pharm Pharmacol 2013, 10.1111/jphp.12148.
    • (2013) J Pharm Pharmacol
    • Kosaraju, J.1    Murthy, V.2    Khatwal, R.B.3    Dubala, A.4    Chinni, S.5    Muthureddy Nataraj, S.K.6
  • 9
    • 34247324303 scopus 로고    scopus 로고
    • Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein
    • Grunblatt E., Salkovic-Petrisic M., Osmanovic J., Riederer P., Hoyer S. Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein. J Neurochem 2007, 101:757-770.
    • (2007) J Neurochem , vol.101 , pp. 757-770
    • Grunblatt, E.1    Salkovic-Petrisic, M.2    Osmanovic, J.3    Riederer, P.4    Hoyer, S.5
  • 11
    • 15244350991 scopus 로고    scopus 로고
    • Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease
    • de la Monte S.M., Wands J.R. Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease. J Alzheimers Dis 2005, 7:45-61.
    • (2005) J Alzheimers Dis , vol.7 , pp. 45-61
    • de la Monte, S.M.1    Wands, J.R.2
  • 12
    • 84897383230 scopus 로고    scopus 로고
    • AAD-2004 attenuates progressive neuronal loss in the brain of Tg-betaCTF99/B6 mouse model of Alzheimer disease
    • Baek I.S., Kim T.K., Seo J.S., Lee K.W., Lee Y.A., Cho J., et al. AAD-2004 attenuates progressive neuronal loss in the brain of Tg-betaCTF99/B6 mouse model of Alzheimer disease. Exp Neurobiol 2013, 22:31-37.
    • (2013) Exp Neurobiol , vol.22 , pp. 31-37
    • Baek, I.S.1    Kim, T.K.2    Seo, J.S.3    Lee, K.W.4    Lee, Y.A.5    Cho, J.6
  • 13
    • 33845334511 scopus 로고    scopus 로고
    • High-performance liquid chromatographic analysis of pterostilbene in biological fluids using fluorescence detection
    • Remsberg C.M., Yáñez J.A., Roupe K.A., Davies N.M. High-performance liquid chromatographic analysis of pterostilbene in biological fluids using fluorescence detection. J Pharm Biomed Anal 2007, 43:250-254.
    • (2007) J Pharm Biomed Anal , vol.43 , pp. 250-254
    • Remsberg, C.M.1    Yáñez, J.A.2    Roupe, K.A.3    Davies, N.M.4
  • 14
    • 16644392852 scopus 로고    scopus 로고
    • Protective effect of Eugenia jambolana seed kernel on tissue antioxidants in streptozotocin-induced diabetic rats
    • Ravi K., Ramachandran B., Subramanian S. Protective effect of Eugenia jambolana seed kernel on tissue antioxidants in streptozotocin-induced diabetic rats. Biol Pharm Bull 2004, 27:1212-1217.
    • (2004) Biol Pharm Bull , vol.27 , pp. 1212-1217
    • Ravi, K.1    Ramachandran, B.2    Subramanian, S.3
  • 16
    • 34248579096 scopus 로고    scopus 로고
    • Estimation of total phenolic content and other oxidation substrates in plant tissues using Folin-Ciocalteu reagent
    • Ainsworth E.A., Gillespie K.M. Estimation of total phenolic content and other oxidation substrates in plant tissues using Folin-Ciocalteu reagent. Nat Protoc 2007, 2:875-877.
    • (2007) Nat Protoc , vol.2 , pp. 875-877
    • Ainsworth, E.A.1    Gillespie, K.M.2
  • 17
    • 84863393470 scopus 로고    scopus 로고
    • Withania somnifera reverses Alzheimer's disease pathology by enhancing low-density lipoprotein receptor-related protein in liver
    • Sehgal N., Gupta A., Valli R.K., Joshi S.D., Mills J.T., Hamel E., et al. Withania somnifera reverses Alzheimer's disease pathology by enhancing low-density lipoprotein receptor-related protein in liver. Proc Natl Acad Sci USA 2012, 109:3510-3515.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 3510-3515
    • Sehgal, N.1    Gupta, A.2    Valli, R.K.3    Joshi, S.D.4    Mills, J.T.5    Hamel, E.6
  • 18
    • 0029039965 scopus 로고
    • Holeboard maze-learning deficits and brain monoaminergic neurotransmitter concentrations in rats after intracerebroventricular injection of 3-Bromopyruvate
    • Froelich L., Ding A., Hoyers S. Holeboard maze-learning deficits and brain monoaminergic neurotransmitter concentrations in rats after intracerebroventricular injection of 3-Bromopyruvate. Pharmacol Biochem Behav 1995, 51:917-922.
    • (1995) Pharmacol Biochem Behav , vol.51 , pp. 917-922
    • Froelich, L.1    Ding, A.2    Hoyers, S.3
  • 19
    • 84870839756 scopus 로고    scopus 로고
    • Comparison of neuroprotective effects of five major lipophilic diterpenoids from Danshen extract against experimentally induced transient cerebral ischemic damage
    • Park O.K., Choi J.H., Park J.H., Kim I.H., Yan B.C., Ahn J.H., et al. Comparison of neuroprotective effects of five major lipophilic diterpenoids from Danshen extract against experimentally induced transient cerebral ischemic damage. Fitoterapia 2012, 83:1666-1674.
    • (2012) Fitoterapia , vol.83 , pp. 1666-1674
    • Park, O.K.1    Choi, J.H.2    Park, J.H.3    Kim, I.H.4    Yan, B.C.5    Ahn, J.H.6
  • 20
    • 33845468278 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV (DPP IV) inhibitors: a newly emerging drug class for the treatment of type 2 diabetes
    • Green B.D., Peter R.F., Clifford J.B. Dipeptidyl peptidase IV (DPP IV) inhibitors: a newly emerging drug class for the treatment of type 2 diabetes. Diab Vasc Dis Res 2006, 3:159-165.
    • (2006) Diab Vasc Dis Res , vol.3 , pp. 159-165
    • Green, B.D.1    Peter, R.F.2    Clifford, J.B.3
  • 21
    • 0036198285 scopus 로고    scopus 로고
    • Interactions of glucagon-like peptide-1 (GLP-1) with the blood-brain barrier
    • Kastin A.J., Akerstrom V., Pan W. Interactions of glucagon-like peptide-1 (GLP-1) with the blood-brain barrier. J Mol Neurosci 2002, 18:7-14.
    • (2002) J Mol Neurosci , vol.18 , pp. 7-14
    • Kastin, A.J.1    Akerstrom, V.2    Pan, W.3
  • 22
    • 69549128161 scopus 로고    scopus 로고
    • Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system
    • Hamilton A., Holscher C. Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system. Neuroreport 2009, 20:1161-1166.
    • (2009) Neuroreport , vol.20 , pp. 1161-1166
    • Hamilton, A.1    Holscher, C.2
  • 23
    • 77953880083 scopus 로고    scopus 로고
    • Incretin analogues that have been developed to treat type 2 diabetes hold promise as a novel treatment strategy for Alzheimer's disease
    • Holscher C. Incretin analogues that have been developed to treat type 2 diabetes hold promise as a novel treatment strategy for Alzheimer's disease. Recent Pat CNS Drug Discov 2010, 5:109-117.
    • (2010) Recent Pat CNS Drug Discov , vol.5 , pp. 109-117
    • Holscher, C.1
  • 24
    • 84867577041 scopus 로고    scopus 로고
    • Amelioration of neurodegenerative changes in cellular and rat models of diabetes-related Alzheimer's disease by exendin-4
    • Chen S., Liu A.R., An F.M., Yao W.B., Gao X.D. Amelioration of neurodegenerative changes in cellular and rat models of diabetes-related Alzheimer's disease by exendin-4. Age (Dordr) 2012, 34:1211-1224.
    • (2012) Age (Dordr) , vol.34 , pp. 1211-1224
    • Chen, S.1    Liu, A.R.2    An, F.M.3    Yao, W.B.4    Gao, X.D.5
  • 25
    • 84855548096 scopus 로고    scopus 로고
    • 8) glucagon-like peptide-1 prevents tau hyperphosphorylation, impairment of spatial learning and ultra-structural cellular damage induced by streptozotocin in rat brains
    • 8) glucagon-like peptide-1 prevents tau hyperphosphorylation, impairment of spatial learning and ultra-structural cellular damage induced by streptozotocin in rat brains. Eur J Pharmacol 2012, 674:280-286.
    • (2012) Eur J Pharmacol , vol.674 , pp. 280-286
    • Li, L.1    Zhang, Z.F.2    Holscher, C.3    Gao, C.4    Jiang, Y.H.5    Liu, Y.Z.6
  • 26
    • 82755176046 scopus 로고    scopus 로고
    • Val(8) GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice
    • Gengler S., McClean P.L., McCurtin R., Gault V.A., Holscher C. Val(8) GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice. Neurobiol Aging 2010, 33:265-276.
    • (2010) Neurobiol Aging , vol.33 , pp. 265-276
    • Gengler, S.1    McClean, P.L.2    McCurtin, R.3    Gault, V.A.4    Holscher, C.5
  • 27
    • 33751168074 scopus 로고    scopus 로고
    • 7-But-2-ynyl-9-(6-methoxy-pyridin-3-yl)-6-piperazin-1-yl-7,9- dihydro-purin-8-one is a novel competitive and selective inhibitor of dipeptidyl peptidase IV with an antihyperglycemic activity
    • Yamazaki K., Yasuda N., Inoue T., Nagakura T., Kira K., Shinoda M., et al. 7-But-2-ynyl-9-(6-methoxy-pyridin-3-yl)-6-piperazin-1-yl-7,9- dihydro-purin-8-one is a novel competitive and selective inhibitor of dipeptidyl peptidase IV with an antihyperglycemic activity. J Pharmacol Exp Ther 2006, 319:1253-1257.
    • (2006) J Pharmacol Exp Ther , vol.319 , pp. 1253-1257
    • Yamazaki, K.1    Yasuda, N.2    Inoue, T.3    Nagakura, T.4    Kira, K.5    Shinoda, M.6
  • 28
    • 0036966876 scopus 로고    scopus 로고
    • The glucagon-like peptides: a new genre in therapeutic targets for intervention in Alzheimer's disease
    • Perry T., Greig N.H. The glucagon-like peptides: a new genre in therapeutic targets for intervention in Alzheimer's disease. J Alzheimers Dis 2002, 4:487-496.
    • (2002) J Alzheimers Dis , vol.4 , pp. 487-496
    • Perry, T.1    Greig, N.H.2
  • 29
    • 0141461415 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor is involved in learning and neuroprotection
    • During M.J., Cao L., Zuzga D.S., Francis J.S., Fitzsimons H.L., Jiao X., et al. Glucagon-like peptide-1 receptor is involved in learning and neuroprotection. Nat Med 2003, 9:1173-1179.
    • (2003) Nat Med , vol.9 , pp. 1173-1179
    • During, M.J.1    Cao, L.2    Zuzga, D.S.3    Francis, J.S.4    Fitzsimons, H.L.5    Jiao, X.6
  • 30
    • 74949100388 scopus 로고    scopus 로고
    • Modeling sporadic Alzheimer's disease: the insulin resistant brain state generates multiple long-term morphobiological abnormalities including hyperphosphorylated tau protein and amyloid-beta
    • Salkovic-Petrisic M., Osmanovic J., Grunblatt E., Riederer P., Hoyer S. Modeling sporadic Alzheimer's disease: the insulin resistant brain state generates multiple long-term morphobiological abnormalities including hyperphosphorylated tau protein and amyloid-beta. J Alzheimers Dis 2009, 18:729-750.
    • (2009) J Alzheimers Dis , vol.18 , pp. 729-750
    • Salkovic-Petrisic, M.1    Osmanovic, J.2    Grunblatt, E.3    Riederer, P.4    Hoyer, S.5
  • 31
    • 0027258525 scopus 로고
    • The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease
    • Jarrett J.T., Berger E.P., Lansbury P.T. The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry 1993, 32:4693-4697.
    • (1993) Biochemistry , vol.32 , pp. 4693-4697
    • Jarrett, J.T.1    Berger, E.P.2    Lansbury, P.T.3
  • 32
    • 0034647786 scopus 로고    scopus 로고
    • Oligomerization and toxicity of beta-amyloid-42 implicated in Alzheimer's disease
    • El-Agnaf O.M., Mahil D.S., Patel B.P., Austen B.M. Oligomerization and toxicity of beta-amyloid-42 implicated in Alzheimer's disease. Biochem Biophys Res Commun 2000, 273:1003-1007.
    • (2000) Biochem Biophys Res Commun , vol.273 , pp. 1003-1007
    • El-Agnaf, O.M.1    Mahil, D.S.2    Patel, B.P.3    Austen, B.M.4
  • 35
    • 4043167747 scopus 로고    scopus 로고
    • Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
    • Oddo S., Billings L., Kesslak J.P., Cribbs D.H., Laferla F.M. Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome. Neuron 2004, 43:321-332.
    • (2004) Neuron , vol.43 , pp. 321-332
    • Oddo, S.1    Billings, L.2    Kesslak, J.P.3    Cribbs, D.H.4    Laferla, F.M.5
  • 36
    • 0035910306 scopus 로고    scopus 로고
    • Intrecerbroventricular injection of streptozotocin in rats produces both oxidative stress in the brain and cognitive impairment
    • Sharma M., Gupta Y.K. Intrecerbroventricular injection of streptozotocin in rats produces both oxidative stress in the brain and cognitive impairment. Life Sci 2001, 68:1021-1029.
    • (2001) Life Sci , vol.68 , pp. 1021-1029
    • Sharma, M.1    Gupta, Y.K.2
  • 37
    • 40049096164 scopus 로고    scopus 로고
    • Modulation of celecoxib- and streptozotocin-induced experimental dementia of Alzheimer's disease by Pitavastatin and Donepezil
    • Sharma B., Singh N., Singh M. Modulation of celecoxib- and streptozotocin-induced experimental dementia of Alzheimer's disease by Pitavastatin and Donepezil. J Psychopharmacol 2008, 22:162-171.
    • (2008) J Psychopharmacol , vol.22 , pp. 162-171
    • Sharma, B.1    Singh, N.2    Singh, M.3
  • 38
    • 67649295306 scopus 로고    scopus 로고
    • Chronic treatment with Tocotrienol, an isoform of vitamin E, prevents intracerebroventricular streptozotocin-induced cognitive impairment and oxidative-nitrosative stress in rats
    • Tiwari V., Kuhad A., Bishnoi M., Chopra K. Chronic treatment with Tocotrienol, an isoform of vitamin E, prevents intracerebroventricular streptozotocin-induced cognitive impairment and oxidative-nitrosative stress in rats. Pharmacol Biochem Behav 2009, 93:183-189.
    • (2009) Pharmacol Biochem Behav , vol.93 , pp. 183-189
    • Tiwari, V.1    Kuhad, A.2    Bishnoi, M.3    Chopra, K.4
  • 39
    • 79953252716 scopus 로고    scopus 로고
    • Improvement of brain energy metabolism and cholinergic functions contributes to the beneficial effects of silibinin against streptozotocin induced memory impairment
    • Tota S., Kamat P.K., Shukla R., Nath C. Improvement of brain energy metabolism and cholinergic functions contributes to the beneficial effects of silibinin against streptozotocin induced memory impairment. Behav Brain Res 2011, 221:207-215.
    • (2011) Behav Brain Res , vol.221 , pp. 207-215
    • Tota, S.1    Kamat, P.K.2    Shukla, R.3    Nath, C.4
  • 40
    • 0032854997 scopus 로고    scopus 로고
    • Hippocampal involvement in spatial and working memory: a structural MRI analysis of patients with unilateral mesial temporal lobe sclerosis
    • Abrahams S., Morris R.G., Polkey C.E., Jarosz J.M., Cox T.C., Graves M., et al. Hippocampal involvement in spatial and working memory: a structural MRI analysis of patients with unilateral mesial temporal lobe sclerosis. Brain Cogn 1999, 41:39-65.
    • (1999) Brain Cogn , vol.41 , pp. 39-65
    • Abrahams, S.1    Morris, R.G.2    Polkey, C.E.3    Jarosz, J.M.4    Cox, T.C.5    Graves, M.6
  • 41
    • 70349750314 scopus 로고    scopus 로고
    • Consumption of grape seed extract prevents amyloid-β deposition and attenuates inflammation in brain of an Alzheimer's disease mouse
    • Wang Y.J., Thomas P., Zhong J.H., Bi F.F., Kosaraju S., Pollard A., et al. Consumption of grape seed extract prevents amyloid-β deposition and attenuates inflammation in brain of an Alzheimer's disease mouse. Neurotox Res 2009, 15:3-14.
    • (2009) Neurotox Res , vol.15 , pp. 3-14
    • Wang, Y.J.1    Thomas, P.2    Zhong, J.H.3    Bi, F.F.4    Kosaraju, S.5    Pollard, A.6
  • 42
    • 75749128269 scopus 로고    scopus 로고
    • Effect of chronic treatment of carvedilol on oxidative stress in an intracerebroventricular streptozotocin induced model of dementia in rats
    • Prakash A.K., Kumar A. Effect of chronic treatment of carvedilol on oxidative stress in an intracerebroventricular streptozotocin induced model of dementia in rats. J Pharm Pharmacol 2009, 61:1665-1672.
    • (2009) J Pharm Pharmacol , vol.61 , pp. 1665-1672
    • Prakash, A.K.1    Kumar, A.2
  • 43
    • 0030669036 scopus 로고    scopus 로고
    • The pathogenesis of senile plaques
    • Dickson D.W. The pathogenesis of senile plaques. J Neuropathol Exp Neurol 1997, 56:321-339.
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 321-339
    • Dickson, D.W.1
  • 44
    • 0035831189 scopus 로고    scopus 로고
    • Beta-amyloid-induced glial expression of both pro- and anti- inflammatory cytokines in cerebral cortex of aged and transgenic transgenicTg2576 mice with Alzheimer plaque pathology
    • Apelt J., Schliebs R. Beta-amyloid-induced glial expression of both pro- and anti- inflammatory cytokines in cerebral cortex of aged and transgenic transgenicTg2576 mice with Alzheimer plaque pathology. Brain Res 2001, 894:21-30.
    • (2001) Brain Res , vol.894 , pp. 21-30
    • Apelt, J.1    Schliebs, R.2
  • 45
    • 33748471099 scopus 로고    scopus 로고
    • Inflammation in Alzheimer disease: driving force, bystander or beneficial response
    • Wyss-Coray T. Inflammation in Alzheimer disease: driving force, bystander or beneficial response. Nat Med 2006, 12:1005-1015.
    • (2006) Nat Med , vol.12 , pp. 1005-1015
    • Wyss-Coray, T.1
  • 46
    • 84858707110 scopus 로고    scopus 로고
    • The glucagon-like peptide 1 analog liraglutide reduces TNF-α-induced oxidative stress and inflammation in endothelial cells
    • Shiraki A., Oyama J., Komoda H., Asaka M., Komatsu A., Sakuma M., et al. The glucagon-like peptide 1 analog liraglutide reduces TNF-α-induced oxidative stress and inflammation in endothelial cells. Atherosclerosis 2012, 221:375-382.
    • (2012) Atherosclerosis , vol.221 , pp. 375-382
    • Shiraki, A.1    Oyama, J.2    Komoda, H.3    Asaka, M.4    Komatsu, A.5    Sakuma, M.6


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