메뉴 건너뛰기




Volumn 61, Issue 12, 2009, Pages 1665-1672

Effect of chronic treatment of carvedilol on oxidative stress in an intracerebroventricular streptozotocin induced model of dementia in rats

Author keywords

Carvedilol; Dementia; Neuroprotection; Oxidative stress; Streptozotocin

Indexed keywords

ACETYLCHOLINESTERASE; CARVEDILOL; CATALASE; GLUTATHIONE; MALONALDEHYDE; NITRATE; NITRITE; PROTEIN; STREPTOZOCIN; SUPEROXIDE DISMUTASE;

EID: 75749128269     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp/61.12.0012     Document Type: Article
Times cited : (29)

References (49)
  • 1
    • 0025908356 scopus 로고
    • The consortium to establish a registry for Alzheimer's disease. Part II. Standardization of the neuropathologic assessment of Alzheimer's disease
    • Mirra SS et al. The consortium to establish a registry for Alzheimer's disease. Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 1991; 41: 479-486.
    • (1991) Neurology , vol.41 , pp. 479-486
    • Mirra, S.S.1
  • 2
    • 33947606911 scopus 로고    scopus 로고
    • Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease
    • Calabrese V et al. Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease. Antioxid Redox Signal 2006; 8: 1975-1986.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1975-1986
    • Calabrese, V.1
  • 3
    • 0027496238 scopus 로고
    • A radical hypothesis for neurodegeneration
    • Olanow CW. A radical hypothesis for neurodegeneration. Trends Neurosci 1993; 16: 439-444.
    • (1993) Trends Neurosci , vol.16 , pp. 439-444
    • Olanow, C.W.1
  • 4
    • 34249027009 scopus 로고    scopus 로고
    • Connecting TNF-a signaling pathway to iNOS expression in a mouse model of Alzheimer's disease: Relevance for the behavioral and synaptic deficits induced by amyloid-β protein
    • Medeiros R et al. Connecting TNF-a signaling pathway to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by amyloid-β protein. J Neurosci 2007; 27: 5394-5404.
    • (2007) J Neurosci , vol.27 , pp. 5394-5404
    • Medeiros, R.1
  • 5
    • 20944442186 scopus 로고    scopus 로고
    • Alzheimer's associated inflammation, potential drug targets and future therapies
    • Stuchbury G, Münch G. Alzheimer's associated inflammation, potential drug targets and future therapies. J Neural Transm 2005; 112: 429-453.
    • (2005) J Neural Transm , vol.112 , pp. 429-453
    • Stuchbury, G.1    Münch, G.2
  • 6
    • 0345276565 scopus 로고    scopus 로고
    • Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
    • Mandelkow EM et al. Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses. Neurobiol Aging 2003; 24: 1079-1085.
    • (2003) Neurobiol Aging , vol.24 , pp. 1079-1085
    • Mandelkow, E.M.1
  • 7
    • 42649127765 scopus 로고    scopus 로고
    • Improvement of short-term memory performance in aged beagles by a nutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine
    • Araujo JA et al. Improvement of short-term memory performance in aged beagles by a nutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine. Can Vet J 2008; 49: 379-385.
    • (2008) Can Vet J , vol.49 , pp. 379-385
    • Araujo, J.A.1
  • 8
    • 62349089251 scopus 로고    scopus 로고
    • Oxidative damage and cognitive dysfunction: Antioxidant treatments to promote healthy brain aging
    • Head E. Oxidative damage and cognitive dysfunction: antioxidant treatments to promote healthy brain aging. Neurochem Res 2009; 34: 670-678.
    • (2009) Neurochem Res , vol.34 , pp. 670-678
    • Head, E.1
  • 9
    • 0033870574 scopus 로고    scopus 로고
    • The novel β-blocker, carvedilol, provides neuroprotection in transient focal stroke
    • Savitz SI et al. The novel β-blocker, carvedilol, provides neuroprotection in transient focal stroke. J Cereb Blood Flow Metab 2000; 20: 1197-1204.
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 1197-1204
    • Savitz, S.I.1
  • 10
    • 0037176966 scopus 로고    scopus 로고
    • Differential effects of carvedilol, metoprolol and propranolol on left ventricular remodeling after coronary stenosis or after permanent coronary occlusion in rats
    • Yaoita H et al. Differential effects of carvedilol, metoprolol and propranolol on left ventricular remodeling after coronary stenosis or after permanent coronary occlusion in rats. Circulation 2002; 105: 975-980.
    • (2002) Circulation , vol.105 , pp. 975-980
    • Yaoita, H.1
  • 11
    • 0033681003 scopus 로고    scopus 로고
    • Effects of carvedilol and its analog BM-910228 on mitochondrial function and oxidative stress
    • Abreu RMV et al. Effects of carvedilol and its analog BM-910228 on mitochondrial function and oxidative stress. J Pharmacol Exp Ther 2000; 295: 1022-1030.
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 1022-1030
    • Abreu, R.M.V.1
  • 12
    • 0026470908 scopus 로고
    • Neuroprotective effects of carvedilol, a new antihypertensive agent, in cultured rat cerebellar neurons and in gerbil global brain ischemia
    • Lysko PG et al. Neuroprotective effects of carvedilol, a new antihypertensive agent, in cultured rat cerebellar neurons and in gerbil global brain ischemia. Stroke 1992; 23: 1630-1636.
    • (1992) Stroke , vol.23 , pp. 1630-1636
    • Lysko, P.G.1
  • 13
    • 0036273891 scopus 로고    scopus 로고
    • Carvedilol attenuates neuroleptic-induced orofacial dyskinesia: Possible antioxidant mechanisms
    • Naidu PS et al. Carvedilol attenuates neuroleptic-induced orofacial dyskinesia: possible antioxidant mechanisms. Br J Pharmacol 2002; 136: 193-200.
    • (2002) Br J Pharmacol , vol.136 , pp. 193-200
    • Naidu, P.S.1
  • 14
    • 0030430050 scopus 로고    scopus 로고
    • Carvedilol, a new beta adrenoceptor blocker and free radical scavenger attenuates myocardial ischemia reperfusion injury in hypercholesterolemic rabbits
    • Ma XL et al. Carvedilol, a new beta adrenoceptor blocker and free radical scavenger attenuates myocardial ischemia reperfusion injury in hypercholesterolemic rabbits. J Pharmacol Exp Ther 1996; 277: 128-136.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 128-136
    • Ma, X.L.1
  • 15
    • 0036357389 scopus 로고    scopus 로고
    • Salvage of cyclosporine A-induced oxidative stress and renal dysfunction by carvedilol
    • Padi SS, Chopra K. Salvage of cyclosporine A-induced oxidative stress and renal dysfunction by carvedilol. Nephron 2002; 92: 685-692.
    • (2002) Nephron , vol.92 , pp. 685-692
    • Padi, S.S.1    Chopra, K.2
  • 16
    • 0035879973 scopus 로고    scopus 로고
    • Radical-scavenging and iron-chelating properties of carvedilol, an antihypertensive drug with antioxidative activity
    • Oettl K et al. Radical-scavenging and iron-chelating properties of carvedilol, an antihypertensive drug with antioxidative activity. Biochem Pharmacol 2001; 62: 241-248.
    • (2001) Biochem Pharmacol , vol.62 , pp. 241-248
    • Oettl, K.1
  • 17
    • 0142121555 scopus 로고    scopus 로고
    • Antioxidant properties of carvedilol: Inhibition of lipid peroxidation, protein oxidation and superoxide generation
    • Suzuki Y et al. Antioxidant properties of carvedilol: inhibition of lipid peroxidation, protein oxidation and superoxide generation. Neurol Res 2003; 25: 749-753.
    • (2003) Neurol Res , vol.25 , pp. 749-753
    • Suzuki, Y.1
  • 18
    • 0028648889 scopus 로고
    • Carvedilol, a new antihypertensive drug with unique antioxidant activity: Potential role in cerebroprotection
    • Yue TL et al. Carvedilol, a new antihypertensive drug with unique antioxidant activity: potential role in cerebroprotection. Ann NY Acad Sci 1994; 738: 230-242.
    • (1994) Ann NY Acad Sci , vol.738 , pp. 230-242
    • Yue, T.L.1
  • 19
    • 0033569444 scopus 로고    scopus 로고
    • Common structural features determine the effectiveness of carvedilol, daunomycin and rolitetracycline as inhibitors of Alzheimer β-amyloid fibril formation
    • Howlett DR et al. Common structural features determine the effectiveness of carvedilol, daunomycin and rolitetracycline as inhibitors of Alzheimer β-amyloid fibril formation. Biochem J 1999; 343: 419-423.
    • (1999) Biochem J , vol.343 , pp. 419-423
    • Howlett, D.R.1
  • 20
    • 0035910306 scopus 로고    scopus 로고
    • Intracerebroventricular injection of streptozotocin in rats produces both oxidative stress in the brain and cognitive impairment
    • Sharma M, Gupta YK. Intracerebroventricular injection of streptozotocin in rats produces both oxidative stress in the brain and cognitive impairment. Life Sci 2001; 68: 1021-1029.
    • (2001) Life Sci , vol.68 , pp. 1021-1029
    • Sharma, M.1    Gupta, Y.K.2
  • 21
    • 0031797937 scopus 로고    scopus 로고
    • Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats
    • Lannert H, Hoyer S. Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats. Behav Neurosci 1998; 112: 1199-1208.
    • (1998) Behav Neurosci , vol.112 , pp. 1199-1208
    • Lannert, H.1    Hoyer, S.2
  • 22
    • 0028915835 scopus 로고
    • Spatial discrimination learning and choline acetyltransferase activity in streptozotocin-treated rats: Effects of chronic treatment with acetyl-L-carnitine
    • Prickaerts J et al. Spatial discrimination learning and choline acetyltransferase activity in streptozotocin-treated rats: effects of chronic treatment with acetyl-L-carnitine. Brain Res 1995; 674: 142-146.
    • (1995) Brain Res , vol.674 , pp. 142-146
    • Prickaerts, J.1
  • 24
    • 33750488783 scopus 로고    scopus 로고
    • Differential effects of cyclooxygenase inhibitors on intracerebroventricular colchicine-induced dysfunction and oxidative stress in rats
    • Kumar A et al. Differential effects of cyclooxygenase inhibitors on intracerebroventricular colchicine-induced dysfunction and oxidative stress in rats. Eur J Pharmacol 2006; 551: 58-66.
    • (2006) Eur J Pharmacol , vol.551 , pp. 58-66
    • Kumar, A.1
  • 25
    • 0032551572 scopus 로고    scopus 로고
    • Possible role of nitric oxide in the nootropic and antiamnesic effects of neurosteroids on aging and dizocilpine-induced learning impairment
    • Reddy DS, Kulkarni SK. Possible role of nitric oxide in the nootropic and antiamnesic effects of neurosteroids on aging and dizocilpine-induced learning impairment. Brain Res 1998; 799: 215-229.
    • (1998) Brain Res , vol.799 , pp. 215-229
    • Reddy, D.S.1    Kulkarni, S.K.2
  • 26
    • 0013914976 scopus 로고
    • Mechanism of lipid peroxide formation in animal tissues
    • Wills ED. Mechanism of lipid peroxide formation in animal tissues. Biochem J 1966; 99: 667-676.
    • (1966) Biochem J , vol.99 , pp. 667-676
    • Wills, E.D.1
  • 27
    • 3042934967 scopus 로고
    • Tissue sulfhydryl groups
    • Ellman GL. Tissue sulfhydryl groups. Arch Biochem Biophys 1959; 82: 48 670-48 677.
    • (1959) Arch Biochem Biophys , vol.82
    • Ellman, G.L.1
  • 28
    • 58549096967 scopus 로고
    • Analysis of nitrate, nitrite and (15 N) nitrate in biological fluids
    • Green LC et al. Analysis of nitrate, nitrite and (15 N) nitrate in biological fluids. J Biol Chem 1982; 193: 265-275.
    • (1982) J Biol Chem , vol.193 , pp. 265-275
    • Green, L.C.1
  • 29
    • 0017804313 scopus 로고
    • Generation of superoxide radical during auto-oxidation of hydroxylamine and an assay for superoxide dismutase
    • Kono Y. Generation of superoxide radical during auto-oxidation of hydroxylamine and an assay for superoxide dismutase. Arch Biochem Biophys 1978; 186: 189-195.
    • (1978) Arch Biochem Biophys , vol.186 , pp. 189-195
    • Kono, Y.1
  • 30
    • 0343075899 scopus 로고
    • Bergmeyer HU, ed, New York: Academic Press
    • Luck H. Catalase. In: Bergmeyer HU, ed. Methods of Enzymatic Analysis. New York: Academic Press, 1978: 885-893.
    • (1978) Methods of Enzymatic Analysis , pp. 885-893
    • Catalase, L.H.1
  • 31
    • 33644811612 scopus 로고
    • A new and rapid colorimetric determination of acetylcholinesterase activity
    • Ellman GL et al. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 1961; 7: 88-95.
    • (1961) Biochem Pharmacol , vol.7 , pp. 88-95
    • Ellman, G.L.1
  • 32
    • 29744466425 scopus 로고
    • Determination of serum proteins by means of Biuret reaction
    • Gornall AG et al. Determination of serum proteins by means of Biuret reaction. J Biol Chem 1949; 177: 751-766.
    • (1949) J Biol Chem , vol.177 , pp. 751-766
    • Gornall, A.G.1
  • 33
    • 75749149793 scopus 로고    scopus 로고
    • Effect of donepezil and tacrine on oxidative stress in intracerebral streptozotocin-induced model of dementia in mice
    • Saxena G et al. Effect of donepezil and tacrine on oxidative stress in intracerebral streptozotocin-induced model of dementia in mice. Eur J Pharmacol 2008; 58: 1283-1289.
    • (2008) Eur J Pharmacol , vol.58 , pp. 1283-1289
    • Saxena, G.1
  • 34
    • 0037063709 scopus 로고    scopus 로고
    • Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats
    • Sharma M, Gupta YK. Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats. Life Sci 2002; 71: 2489-2498.
    • (2002) Life Sci , vol.71 , pp. 2489-2498
    • Sharma, M.1    Gupta, Y.K.2
  • 35
    • 0002881583 scopus 로고
    • Carvedilol, a new vasodilator and β-adrenoceptor antagonist, inhibits oxygen-radical induced lipid peroxidation in swine ventricular membranes
    • Yue TL et al. Carvedilol, a new vasodilator and β-adrenoceptor antagonist, inhibits oxygen-radical induced lipid peroxidation in swine ventricular membranes. Pharmacol Res Commun 1992; 1: 27-35.
    • (1992) Pharmacol Res Commun , vol.1 , pp. 27-35
    • Yue, T.L.1
  • 36
    • 0026779879 scopus 로고
    • Carvedilol, a new vasodilator and β-adrenoceptor antagonist, is an antioxidant and free radical scavenger
    • Yue TL et al. Carvedilol, a new vasodilator and β-adrenoceptor antagonist, is an antioxidant and free radical scavenger. J Pharmacol Exp Ther 1992; 263: 92-98.
    • (1992) J Pharmacol Exp Ther , vol.263 , pp. 92-98
    • Yue, T.L.1
  • 37
    • 36049018320 scopus 로고    scopus 로고
    • Influence of carvedilol on superoxide generation and enzyme release from stimulated human neutrophils
    • Macickova T et al. Influence of carvedilol on superoxide generation and enzyme release from stimulated human neutrophils. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2005; 149: 389-392.
    • (2005) Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub , vol.149 , pp. 389-392
    • Macickova, T.1
  • 38
    • 0026754564 scopus 로고    scopus 로고
    • Carvedilol: A novel cardiovascular drug with multiple actions
    • Ruffolo RR et al. Carvedilol: a novel cardiovascular drug with multiple actions. Cardiovasc Drug Rev 2007; 10: 127-157.
    • (2007) Cardiovasc Drug Rev , vol.10 , pp. 127-157
    • Ruffolo, R.R.1
  • 39
    • 0030868061 scopus 로고    scopus 로고
    • Carvedilol update IV: Prevention of oxidative stress, cardiac remodeling and progression of congestive heart failure
    • Feuerstein GZ et al. Carvedilol update IV: prevention of oxidative stress, cardiac remodeling and progression of congestive heart failure. Drugs Today 1997; 33: 453-457.
    • (1997) Drugs Today , vol.33 , pp. 453-457
    • Feuerstein, G.Z.1
  • 40
    • 0029125857 scopus 로고
    • Ageing, energy and oxidative stress in neurodegenerative disease
    • Beal MF. Ageing, energy and oxidative stress in neurodegenerative disease. Ann Neurol 1995; 38: 357-366.
    • (1995) Ann Neurol , vol.38 , pp. 357-366
    • Beal, M.F.1
  • 41
    • 0028969188 scopus 로고
    • The relation of oxidative stress and hyperexcitation to neurological disease
    • Bondy CS. The relation of oxidative stress and hyperexcitation to neurological disease. Proc Soc Exp Biol Med 1995; 208: 337-345.
    • (1995) Proc Soc Exp Biol Med , vol.208 , pp. 337-345
    • Bondy, C.S.1
  • 42
    • 0034615834 scopus 로고    scopus 로고
    • Differential vulnerability of primary cultured neurons to nitric oxide excess
    • Fass U et al. Differential vulnerability of primary cultured neurons to nitric oxide excess. Neuroreport 2003; 11: 931-936.
    • (2003) Neuroreport , vol.11 , pp. 931-936
    • Fass, U.1
  • 43
    • 0029147523 scopus 로고
    • Excitotoxins, aging and environmental neurotoxins: Implications for understanding human neurodegenerative diseases
    • Dawson JR et al. Excitotoxins, aging and environmental neurotoxins: implications for understanding human neurodegenerative diseases. Toxicol Appl Pharmacol 1995; 134: 157-167.
    • (1995) Toxicol Appl Pharmacol , vol.134 , pp. 157-167
    • Dawson, J.R.1
  • 44
    • 0034028695 scopus 로고    scopus 로고
    • Anti-NO action of carvedilol in cell-free system and in vascular endothelial cells
    • Yoshioka T et al. Anti-NO action of carvedilol in cell-free system and in vascular endothelial cells. Br J Pharmacol 2000; 129: 1530-1535.
    • (2000) Br J Pharmacol , vol.129 , pp. 1530-1535
    • Yoshioka, T.1
  • 45
    • 4944258716 scopus 로고    scopus 로고
    • The role of inflammation in Alzheimer's disease
    • Tuppo EE, Arias HR. The role of inflammation in Alzheimer's disease. Int J Biochem Cell Biol 2005; 37: 289-305.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 289-305
    • Tuppo, E.E.1    Arias, H.R.2
  • 46
    • 0346368256 scopus 로고    scopus 로고
    • Cardioprotective effects of carvedilol on acute autoimmune myocarditis: Anti-inflammatory effects associated with antioxidant property
    • Yuan Z et al. Cardioprotective effects of carvedilol on acute autoimmune myocarditis: anti-inflammatory effects associated with antioxidant property. Am J Physiol Heart Circ Physiol 2004; 286: H83-H90.
    • (2004) Am J Physiol Heart Circ Physiol , vol.286
    • Yuan, Z.1
  • 47
    • 0033512004 scopus 로고    scopus 로고
    • Inflammatory mediators and stroke: New opportunities for novel therapeutics
    • Barone FC, Feuerstein GZ. Inflammatory mediators and stroke: new opportunities for novel therapeutics. J Cereb Blood Flow Metab 1999; 19: 819-834.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 819-834
    • Barone, F.C.1    Feuerstein, G.Z.2
  • 48
    • 0034932067 scopus 로고    scopus 로고
    • Neuroprotective effects of novel cholinesterase inhibitors derived from rasagiline as potential anti-Alzheimer drugs
    • Weinstock M et al. Neuroprotective effects of novel cholinesterase inhibitors derived from rasagiline as potential anti-Alzheimer drugs. Ann N Y Acad Sci 2001; 939: 148-161.
    • (2001) Ann N Y Acad Sci , vol.939 , pp. 148-161
    • Weinstock, M.1
  • 49
    • 0028223375 scopus 로고
    • Behavioral and biochemical effects of an ICV injection of streptozotocin in old Lewis rats
    • Blokland A, Jolles J. Behavioral and biochemical effects of an ICV injection of streptozotocin in old Lewis rats. Pharmacol Biochem Behav 1994; 47: 833-837.
    • (1994) Pharmacol Biochem Behav , vol.47 , pp. 833-837
    • Blokland, A.1    Jolles, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.