메뉴 건너뛰기




Volumn 74, Issue 7, 2014, Pages 2050-2061

CBP loss cooperates with PTEN haploinsufficiency to drive prostate cancer: Implications for epigenetic therapy

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; HISTONE H3; PANOBINOSTAT; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TRANSCRIPTION FACTOR EZH2;

EID: 84897421206     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-1659     Document Type: Article
Times cited : (38)

References (46)
  • 1
    • 0027937517 scopus 로고
    • High grade prostatic intraepithelial neoplasia (hgpin) and prostatic adenocarcinoma between the ages of 20-69: An autopsy study of 249 cases
    • Sakr WA, Grignon DJ, Crissman JD, Heilbrun LK, Cassin BJ, Pontes JJ, et al. High grade prostatic intraepithelial neoplasia (HGPIN) and prostatic adenocarcinoma between the ages of 20-69: an autopsy study of 249 cases. In Vivo 1994;8:439-43.
    • (1994) Vivo , vol.8 , pp. 439-443
    • Sakr, W.A.1    Grignon, D.J.2    Crissman, J.D.3    Heilbrun, L.K.4    Cassin, B.J.5    Pontes, J.J.6
  • 2
    • 0041914332 scopus 로고    scopus 로고
    • The role of pten in the progression and survival of prostate cancer
    • Deocampo ND, Huang H, Tindall DJ. The role of PTEN in the progression and survival of prostate cancer. Minerva Endocrinol 2003;28: 145-53.
    • (2003) Minerva Endocrinol , vol.28 , pp. 145-153
    • Deocampo, N.D.1    Huang, H.2    Tindall, D.J.3
  • 3
    • 0033200172 scopus 로고    scopus 로고
    • Loss of pten expression in paraffin-embedded primary prostate cancer correlates with high gleason score and advanced stage
    • McMenamin ME, Soung P, Perera S, Kaplan I, Loda M, Sellers WR. Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage. Cancer Res 1999;59:4291-6.
    • (1999) Cancer Res , vol.59 , pp. 4291-4296
    • McMenamin, M.E.1    Soung, P.2    Perera, S.3    Kaplan, I.4    Loda, M.5    Sellers, W.R.6
  • 5
    • 66749100105 scopus 로고    scopus 로고
    • Cooperativity of tmprss2-erg with pi3-kinase pathway activation in prostate oncogenesis
    • King JC, Xu J, Wongvipat J, Hieronymus H, Carver BS, Leung DH, et al. Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis. Nat Genet 2009;41:524-6.
    • (2009) Nat Genet , vol.41 , pp. 524-526
    • King, J.C.1    Xu, J.2    Wongvipat, J.3    Hieronymus, H.4    Carver, B.S.5    Leung, D.H.6
  • 6
    • 0034234237 scopus 로고    scopus 로고
    • Cbp/p300 in cell growth, transformation, and development
    • Goodman RH, Smolik S. CBP/p300 in cell growth, transformation, and development. Genes Dev 2000;14:1553-77.
    • (2000) Genes Dev , vol.14 , pp. 1553-1577
    • Goodman, R.H.1    Smolik, S.2
  • 7
    • 46249112085 scopus 로고    scopus 로고
    • Combinatorial patterns of histone acetylations and methylations in the human genome
    • Wang Z, Zang C, Rosenfeld JA, Schones DE, Barski A, Cuddapah S, et al. Combinatorial patterns of histone acetylations and methylations in the human genome. Nat Genet 2008;40:897-903.
    • (2008) Nat Genet , vol.40 , pp. 897-903
    • Wang, Z.1    Zang, C.2    Rosenfeld, J.A.3    Schones, D.E.4    Barski, A.5    Cuddapah, S.6
  • 8
    • 70350031643 scopus 로고    scopus 로고
    • Cbp-mediated acetylation of histone h3 lysine 27 antagonizes drosophila polycomb silencing
    • Tie F, Banerjee R, Stratton CA, Prasad-Sinha J, Stepanik V, Zlobin A, et al. CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing. Development 2009;136:3131-41.
    • (2009) Development , vol.136 , pp. 3131-3141
    • Tie, F.1    Banerjee, R.2    Stratton, C.A.3    Prasad-Sinha, J.4    Stepanik, V.5    Zlobin, A.6
  • 9
    • 78751611793 scopus 로고    scopus 로고
    • Distinct roles of gcn5/pcaf-mediated h3k9ac and cbp/p300-mediated h3k18/ 27ac in nuclear receptor transactivation
    • Jin Q, Yu LR, Wang L, Zhang Z, Kasper LH, Lee JE, et al. Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/ 27ac in nuclear receptor transactivation. EMBO J 2011;30:249-62.
    • (2011) EMBO J , vol.30 , pp. 249-262
    • Jin, Q.1    Yu, L.R.2    Wang, L.3    Zhang, Z.4    Kasper, L.H.5    Lee, J.E.6
  • 14
    • 1642494790 scopus 로고    scopus 로고
    • Loss of heterozygosity and internal tandem duplication mutations of the cbp gene are frequent events in human esophageal squamous cell carcinoma
    • So CK, Nie Y, Song Y, Yang GY, Chen S, Wei C, et al. Loss of heterozygosity and internal tandem duplication mutations of the CBP gene are frequent events in human esophageal squamous cell carcinoma. Clin Cancer Res 2004;10:19-27.
    • (2004) Clin Cancer Res , vol.10 , pp. 19-27
    • So, C.K.1    Nie, Y.2    Song, Y.3    Yang, G.Y.4    Chen, S.5    Wei, C.6
  • 15
    • 10744222860 scopus 로고    scopus 로고
    • Prostatespecific deletion of the murine pten tumor suppressor gene leads to metastatic prostate cancer
    • Wang S, Gao J, Lei Q, Rozengurt N, Pritchard C, Jiao J, et al. Prostatespecific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer. Cancer Cell 2003;4:209-21.
    • (2003) Cancer Cell , vol.4 , pp. 209-221
    • Wang, S.1    Gao, J.2    Lei, Q.3    Rozengurt, N.4    Pritchard, C.5    Jiao, J.6
  • 16
    • 0035113825 scopus 로고    scopus 로고
    • Generation of a prostate epithelial cell-specific cre transgenic mouse model for tissue-specific gene ablation
    • Wu X, Wu J, Huang J, Powell WC, Zhang J, Matusik RJ, et al. Generation of a prostate epithelial cell-specific Cre transgenic mouse model for tissue-specific gene ablation. Mech Dev 2001;101:61-9.
    • (2001) Mech Dev , vol.101 , pp. 61-69
    • Wu, X.1    Wu, J.2    Huang, J.3    Powell, W.C.4    Zhang, J.5    Matusik, R.J.6
  • 17
    • 0036195102 scopus 로고    scopus 로고
    • Cre/ loxp-mediated inactivation of the murine pten tumor suppressor gene
    • Lesche R, Groszer M, Gao J, Wang Y, Messing A, Sun H, et al. Cre/ loxP-mediated inactivation of the murine Pten tumor suppressor gene. Genesis 2002;32:148-9.
    • (2002) Genesis , vol.32 , pp. 148-149
    • Lesche, R.1    Groszer, M.2    Gao, J.3    Wang, Y.4    Messing, A.5    Sun, H.6
  • 18
    • 23244460597 scopus 로고    scopus 로고
    • Crucial role of p53-dependent cellular senescence in suppression of ptendeficient tumorigenesis
    • Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA, Niki M, et al. Crucial role of p53-dependent cellular senescence in suppression of Ptendeficient tumorigenesis. Nature 2005;436:725-30.
    • (2005) Nature , vol.436 , pp. 725-730
    • Chen, Z.1    Trotman, L.C.2    Shaffer, D.3    Lin, H.K.4    Dotan, Z.A.5    Niki, M.6
  • 19
    • 78149285100 scopus 로고    scopus 로고
    • Cyclindependent kinases regulate epigenetic gene silencing through phosphorylation of ezh2
    • Chen S, Bohrer LR, Rai AN, Pan Y, Gan L, Zhou X, et al. Cyclindependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2. Nat Cell Biol 2010;12:1108-14.
    • (2010) Nat Cell Biol , vol.12 , pp. 1108-1114
    • Chen, S.1    Bohrer, L.R.2    Rai, A.N.3    Pan, Y.4    Gan, L.5    Zhou, X.6
  • 21
    • 0037222317 scopus 로고    scopus 로고
    • The transcriptional co-Activator camp response element-binding protein-binding protein is expressed in prostate cancer and enhances androgen-And anti-Androgen-induced androgen receptor function
    • Comuzzi B, Lambrinidis L, Rogatsch H, Godoy-Tundidor S, Knezevic N, Krhen I, et al. The transcriptional co-Activator cAMP response element-binding protein-binding protein is expressed in prostate cancer and enhances androgen-And anti-Androgen-induced androgen receptor function. Am J Pathol 2003;162:233-41.
    • (2003) Am J Pathol , vol.162 , pp. 233-241
    • Comuzzi, B.1    Lambrinidis, L.2    Rogatsch, H.3    Godoy-Tundidor, S.4    Knezevic, N.5    Krhen, I.6
  • 22
    • 0031964511 scopus 로고    scopus 로고
    • Interfocal heterogeneity of pten/mmac1 gene alterations in multiple metastatic prostate cancer tissues
    • Suzuki H, Freije D, Nusskern DR, Okami K, Cairns P, Sidransky D, et al. Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues. Cancer Res 1998;58:204-9.
    • (1998) Cancer Res , vol.58 , pp. 204-209
    • Suzuki, H.1    Freije, D.2    Nusskern, D.R.3    Okami, K.4    Cairns, P.5    Sidransky, D.6
  • 23
    • 33748038440 scopus 로고    scopus 로고
    • Emergence of androgen independence at early stages of prostate cancer progression in nkx3.1; pten mice
    • Gao H, Ouyang X, Banach-Petrosky WA, Shen MM, Abate-Shen C. Emergence of androgen independence at early stages of prostate cancer progression in Nkx3.1; Pten mice. Cancer Res 2006;66: 7929-33.
    • (2006) Cancer Res , vol.66 , pp. 7929-7933
    • Gao, H.1    Ouyang, X.2    Banach-Petrosky, W.A.3    Shen, M.M.4    Abate-Shen, C.5
  • 24
    • 0036205878 scopus 로고    scopus 로고
    • Differential regulation of the human gene dab2ip in normal and malignant prostatic epithelia: Cloning and characterization
    • Chen H, Pong RC, Wang Z, Hsieh JT. Differential regulation of the human gene DAB2IP in normal and malignant prostatic epithelia: cloning and characterization. Genomics 2002;79:573-81.
    • (2002) Genomics , vol.79 , pp. 573-581
    • Chen, H.1    Pong, R.C.2    Wang, Z.3    Hsieh, J.T.4
  • 25
    • 0037066783 scopus 로고    scopus 로고
    • The mechanism of growth-inhibitory effect of doc-2/dab2 in prostate cancer. Characterization of a novel gtpase-Activating protein associated with n-Terminal domain of doc-2/dab2
    • Wang Z, Tseng CP, Pong RC, Chen H, McConnell JD, Navone N, et al. The mechanism of growth-inhibitory effect of DOC-2/DAB2 in prostate cancer. Characterization of a novel GTPase-Activating protein associated with N-Terminal domain of DOC-2/DAB2. J Biol Chem 2002; 277:12622-31.
    • (2002) J Biol Chem , vol.277 , pp. 12622-12631
    • Wang, Z.1    Tseng, C.P.2    Pong, R.C.3    Chen, H.4    McConnell, J.D.5    Navone, N.6
  • 27
    • 84864876023 scopus 로고    scopus 로고
    • Inner workings and regulatory inputs that control polycomb repressive complex 2
    • O'Meara MM, Simon JA. Inner workings and regulatory inputs that control Polycomb repressive complex 2. Chromosoma 2012;121: 221-34.
    • (2012) Chromosoma , vol.121 , pp. 221-234
    • O'Meara, M.M.1    Simon, J.A.2
  • 28
    • 77953973940 scopus 로고    scopus 로고
    • Characterization of an antagonistic switch between histone h3 lysine 27 methylation and acetylation in the transcriptional regulation of polycomb group target genes
    • Pasini D, Malatesta M, Jung HR, Walfridsson J, Willer A, Olsson L, et al. Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes. Nucleic Acids Res 2010;38: 4958-69.
    • (2010) Nucleic Acids Res , vol.38 , pp. 4958-4969
    • Pasini, D.1    Malatesta, M.2    Jung, H.R.3    Walfridsson, J.4    Willer, A.5    Olsson, L.6
  • 29
    • 0036830642 scopus 로고    scopus 로고
    • Role of histone h3 lysine 27 methylation in polycomb-group silencing
    • Cao R, Wang L, Wang H, Xia L, Erdjument-Bromage H, Tempst P, et al. Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 2002;298:1039-43.
    • (2002) Science , vol.298 , pp. 1039-1043
    • Cao, R.1    Wang, L.2    Wang, H.3    Xia, L.4    Erdjument-Bromage, H.5    Tempst, P.6
  • 30
    • 78649807567 scopus 로고    scopus 로고
    • Phosphorylation of the prc2 component ezh2 is cell cycle-regulated and up-regulates its binding to ncrna
    • Kaneko S, Li G, Son J, Xu CF, Margueron R, Neubert TA, et al. Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA. Genes Dev 2010;24: 2615-20.
    • (2010) Genes Dev , vol.24 , pp. 2615-2620
    • Kaneko, S.1    Li, G.2    Son, J.3    Xu, C.F.4    Margueron, R.5    Neubert, T.A.6
  • 31
    • 80051496158 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 1 (cdk1)-mediated phosphorylation of enhancer of zeste 2 (ezh2) regulates its stability
    • Wu SC, Zhang Y. Cyclin-dependent kinase 1 (CDK1)-mediated phosphorylation of enhancer of zeste 2 (Ezh2) regulates its stability. J Biol Chem 2011;286:28511-9.
    • (2011) J Biol Chem , vol.286 , pp. 28511-28519
    • Wu, S.C.1    Zhang, Y.2
  • 32
    • 13044305289 scopus 로고    scopus 로고
    • Pten modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-Trisphosphate and akt/protein kinase b signaling pathway
    • Sun H, Lesche R, Li DM, Liliental J, Zhang H, Gao J, et al. PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-Trisphosphate and Akt/protein kinase B signaling pathway. Proc Natl Acad Sci U S A 1999;96:6199-204.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 6199-6204
    • Sun, H.1    Lesche, R.2    Li, D.M.3    Liliental, J.4    Zhang, H.5    Gao, J.6
  • 33
    • 13844315463 scopus 로고    scopus 로고
    • Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation
    • Kuzmichev A, Margueron R, Vaquero A, Preissner TS, Scher M, Kirmizis A, et al. Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation. Proc Natl Acad Sci U S A 2005;102:1859-64.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 1859-1864
    • Kuzmichev, A.1    Margueron, R.2    Vaquero, A.3    Preissner, T.S.4    Scher, M.5    Kirmizis, A.6
  • 34
    • 79958764107 scopus 로고    scopus 로고
    • Cell autonomous role of pten in regulating castration-resistant prostate cancer growth
    • Mulholland DJ, Tran LM, Li Y, Cai H, Morim A, Wang S, et al. Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth. Cancer Cell 2011;19:792-804.
    • (2011) Cancer Cell , vol.19 , pp. 792-804
    • Mulholland, D.J.1    Tran, L.M.2    Li, Y.3    Cai, H.4    Morim, A.5    Wang, S.6
  • 35
    • 84878610451 scopus 로고    scopus 로고
    • Brca1 is a negative modulator of the prc2 complex
    • Wang L, Zeng X, Chen S, Ding L, Zhong J, Zhao JC, et al. BRCA1 is a negative modulator of the PRC2 complex. EMBO J 2013;32:1584-97.
    • (2013) EMBO J , vol.32 , pp. 1584-1597
    • Wang, L.1    Zeng, X.2    Chen, S.3    Ding, L.4    Zhong, J.5    Zhao, J.C.6
  • 36
    • 26844520965 scopus 로고    scopus 로고
    • Akt-mediated phosphorylation of ezh2 suppresses methylation of lysine 27 in histone h3
    • Cha TL, Zhou BP, Xia W,Wu Y, Yang CC, Chen CT, et al. Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3. Science 2005;310:306-10.
    • (2005) Science , vol.310 , pp. 306-310
    • Cha, T.L.1    Zhou, B.P.2    Xia, W.3    Wu, Y.4    Yang, C.C.5    Chen, C.T.6
  • 37
    • 84871052080 scopus 로고    scopus 로고
    • Ezh2 oncogenic activity in castration-resistant prostate cancer cells is polycombindependent
    • Xu K, Wu ZJ, Groner AC, He HH, Cai C, Lis RT, et al. EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycombindependent. Science 2012;338:1465-9.
    • (2012) Science , vol.338 , pp. 1465-1469
    • Xu, K.1    Wu, Z.J.2    Groner, A.C.3    He, H.H.4    Cai, C.5    Lis, R.T.6
  • 38
    • 70449494636 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large b-cell lymphoma by inhibiting akt signaling through mtorc2
    • Gupta M, Ansell SM, Novak AJ, Kumar S, Kaufmann SH, Witzig TE. Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2. Blood 2009;114:2926-35.
    • (2009) Blood , vol.114 , pp. 2926-2935
    • Gupta, M.1    Ansell, S.M.2    Novak, A.J.3    Kumar, S.4    Kaufmann, S.H.5    Witzig, T.E.6
  • 39
    • 33748063974 scopus 로고    scopus 로고
    • A phase i study of intravenous lbh589, a novel cinnamic hydroxamic acid analogue histone deacetylase inhibitor, in patients with refractory hematologic malignancies
    • Giles F, Fischer T, Cortes J, Garcia-Manero G, Beck J, Ravandi F, et al. A phase I study of intravenous LBH589, a novel cinnamic hydroxamic acid analogue histone deacetylase inhibitor, in patients with refractory hematologic malignancies. Clin Cancer Res 2006;12:4628-35.
    • (2006) Clin Cancer Res , vol.12 , pp. 4628-4635
    • Giles, F.1    Fischer, T.2    Cortes, J.3    Garcia-Manero, G.4    Beck, J.5    Ravandi, F.6
  • 40
    • 77951884767 scopus 로고    scopus 로고
    • A phase i study of oral panobinostat alone and in combination with docetaxel in patients with castration-resistant prostate cancer
    • Rathkopf D, Wong BY, Ross RW, Anand A, Tanaka E, Woo MM, et al. A phase I study of oral panobinostat alone and in combination with docetaxel in patients with castration-resistant prostate cancer. Cancer Chemother Pharmacol 2010;66:181-9.
    • (2010) Cancer Chemother Pharmacol , vol.66 , pp. 181-189
    • Rathkopf, D.1    Wong, B.Y.2    Ross, R.W.3    Anand, A.4    Tanaka, E.5    Woo, M.M.6
  • 41
    • 84875985004 scopus 로고    scopus 로고
    • Histone deacetylase 3 suppression increases ph domain and leucine-rich repeat phosphatase (phlpp)1 expression in chondrocytes to suppress akt signaling and matrix secretion
    • Bradley EW, Carpio LR, Westendorf JJ. Histone deacetylase 3 suppression increases PH domain and leucine-rich repeat phosphatase (Phlpp)1 expression in chondrocytes to suppress Akt signaling and matrix secretion. J Biol Chem 2013;288:9572-82.
    • (2013) J Biol Chem , vol.288 , pp. 9572-9582
    • Bradley, E.W.1    Carpio, L.R.2    Westendorf, J.J.3
  • 42
    • 84866851740 scopus 로고    scopus 로고
    • Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
    • Peifer M, Fernandez-Cuesta L, Sos ML, George J, Seidel D, Kasper LH, et al. Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat Genet 2012;44: 1104-10.
    • (2012) Nat Genet , vol.44 , pp. 1104-1110
    • Peifer, M.1    Fernandez-Cuesta, L.2    Sos, M.L.3    George, J.4    Seidel, D.5    Kasper, L.H.6
  • 44
    • 0038271762 scopus 로고    scopus 로고
    • Prostate intraepithelial neoplasia induced by prostate restricted akt activation: The mpakt model
    • Majumder PK, Yeh JJ, George DJ, Febbo PG, Kum J, Xue Q, et al. Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model. Proc Natl Acad Sci U S A 2003;100: 7841-6.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 7841-7846
    • Majumder, P.K.1    Yeh, J.J.2    George, D.J.3    Febbo, P.G.4    Kum, J.5    Xue, Q.6
  • 45
    • 0035848705 scopus 로고    scopus 로고
    • Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front
    • Paweletz CP, Charboneau L, Bichsel VE, Simone NL, Chen T, Gillespie JW, et al. Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front. Oncogene 2001;20:1981-9.
    • (2001) Oncogene , vol.20 , pp. 1981-1989
    • Paweletz, C.P.1    Charboneau, L.2    Bichsel, V.E.3    Simone, N.L.4    Chen, T.5    Gillespie, J.W.6
  • 46
    • 84876483693 scopus 로고    scopus 로고
    • Cytoplasmic pten protein loss distinguishes intraductal carcinoma of the prostate from high-grade prostatic intraepithelial neoplasia
    • Lotan TL, Gumuskaya B, Rahimi H, Hicks JL, Iwata T, Robinson BD, et al. Cytoplasmic PTEN protein loss distinguishes intraductal carcinoma of the prostate from high-grade prostatic intraepithelial neoplasia. Mod Pathol 2013;26:587-603.
    • (2013) Mod Pathol , vol.26 , pp. 587-603
    • Lotan, T.L.1    Gumuskaya, B.2    Rahimi, H.3    Hicks, J.L.4    Iwata, T.5    Robinson, B.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.