-
1
-
-
0036535753
-
Recombinant protein expression for therapeutic applications
-
11950561 10.1016/S0958-1669(02)00300-2 1:CAS:528:DC%2BD38Xis1Clt7s%3D
-
Andersen DC, Krummen L (2002) Recombinant protein expression for therapeutic applications. Curr Opin Biotechnol 13(2):117-123
-
(2002)
Curr Opin Biotechnol
, vol.13
, Issue.2
, pp. 117-123
-
-
Andersen, D.C.1
Krummen, L.2
-
2
-
-
83655197847
-
Correlation of gene expression and protein production rate - A system wide study
-
22185473 10.1186/1471-2164-12-616 1:CAS:528:DC%2BC38XivVWitrc%3D
-
Arvas M, Pakula T, Smit B, Rautio J, Koivistoinen H, Jouhten P, Lindfors E, Wiebe M, Penttilä M, Saloheimo M (2011) Correlation of gene expression and protein production rate - a system wide study. BMC Genomics 12(1):616
-
(2011)
BMC Genomics
, vol.12
, Issue.1
, pp. 616
-
-
Arvas, M.1
Pakula, T.2
Smit, B.3
Rautio, J.4
Koivistoinen, H.5
Jouhten, P.6
Lindfors, E.7
Wiebe, M.8
Penttilä, M.9
Saloheimo, M.10
-
3
-
-
33751159209
-
Intracellular signaling by the unfolded protein response
-
16822172 10.1146/annurev.cellbio.21.122303.120200 1:CAS:528: DC%2BD28Xht1yjs7jK
-
Bernales S, Papa FR, Walter P (2006) Intracellular signaling by the unfolded protein response. Annu Rev Cell Dev Biol 22:487
-
(2006)
Annu Rev Cell Dev Biol
, vol.22
, pp. 487
-
-
Bernales, S.1
Papa, F.R.2
Walter, P.3
-
4
-
-
80955180973
-
Reverse engineering of protein secretion by uncoupling of cell cycle phases from growth
-
10.1002/bit.23198 1:CAS:528:DC%2BC3MXhtVagtb3N
-
Buchetics M, Dragosits M, Maurer M, Rebnegger C, Porro D, Sauer M, Gasser B, Mattanovich D (2011) Reverse engineering of protein secretion by uncoupling of cell cycle phases from growth. Biotechnol Bioeng 108(10):2403-2412
-
(2011)
Biotechnol Bioeng
, vol.108
, Issue.10
, pp. 2403-2412
-
-
Buchetics, M.1
Dragosits, M.2
Maurer, M.3
Rebnegger, C.4
Porro, D.5
Sauer, M.6
Gasser, B.7
Mattanovich, D.8
-
5
-
-
34247630099
-
Growth control of the eukaryote cell: A systems biology study in yeast
-
17439666 10.1186/jbiol54
-
Castrillo JI, Zeef LA, Hoyle DC, Zhang N, Hayes A, Gardner DCJ, Cornell MJ, Petty J, Hakes L, Wardleworth L (2007) Growth control of the eukaryote cell: a systems biology study in yeast. J Biol 6(2):4
-
(2007)
J Biol
, vol.6
, Issue.2
, pp. 4
-
-
Castrillo, J.I.1
Zeef, L.A.2
Hoyle, D.C.3
Zhang, N.4
Hayes, A.5
Gardner, D.C.J.6
Cornell, M.J.7
Petty, J.8
Hakes, L.9
Wardleworth, L.10
-
6
-
-
0035149551
-
Remodeling of yeast genome expression in response to environmental changes
-
11179418 10.1091/mbc.12.2.323 1:CAS:528:DC%2BD3MXhtlGjtLg%3D
-
Causton HC, Ren B, Koh SS, Harbison CT, Kanin E, Jennings EG, Lee TI, True HL, Lander ES, Young RA (2001) Remodeling of yeast genome expression in response to environmental changes. Mol Biol Cell 12(2):323-337
-
(2001)
Mol Biol Cell
, vol.12
, Issue.2
, pp. 323-337
-
-
Causton, H.C.1
Ren, B.2
Koh, S.S.3
Harbison, C.T.4
Kanin, E.5
Jennings, E.G.6
Lee, T.I.7
True, H.L.8
Lander, E.S.9
Young, R.A.10
-
7
-
-
43049096460
-
Monitoring of transcriptome and proteome profiles to investigate the cellular response of E. coli towards recombinant protein expression under defined chemostat conditions
-
18405993 10.1016/j.jbiotec.2008.02.013
-
Dürrschmid K, Reischer H, Schmidt-Heck W, Hrebicek T, Guthke R, Rizzi A, Bayer K (2008) Monitoring of transcriptome and proteome profiles to investigate the cellular response of E. coli towards recombinant protein expression under defined chemostat conditions. J Biotechnol 135(1):34-44
-
(2008)
J Biotechnol
, vol.135
, Issue.1
, pp. 34-44
-
-
Dürrschmid, K.1
Reischer, H.2
Schmidt-Heck, W.3
Hrebicek, T.4
Guthke, R.5
Rizzi, A.6
Bayer, K.7
-
8
-
-
49049097132
-
Transcription factor control of growth rate dependent genes in Saccharomyces cerevisiae: A three factor design
-
18638364 10.1186/1471-2164-9-341
-
Fazio A, Jewett M, Daran-Lapujade P, Mustacchi R, Usaite R, Pronk J, Workman C, Nielsen J (2008) Transcription factor control of growth rate dependent genes in Saccharomyces cerevisiae: a three factor design. BMC Genomics 9(1):341
-
(2008)
BMC Genomics
, vol.9
, Issue.1
, pp. 341
-
-
Fazio, A.1
Jewett, M.2
Daran-Lapujade, P.3
Mustacchi, R.4
Usaite, R.5
Pronk, J.6
Workman, C.7
Nielsen, J.8
-
9
-
-
0037361724
-
Towards a cost effective strategy for cutinase production by a recombinant Saccharomyces cerevisiae: Strain physiological aspects
-
12658517 1:CAS:528:DC%2BD3sXitlKht74%3D
-
Ferreira B, Calado C, Van Keulen F, Fonseca L, Cabral J, da Fonseca M (2003) Towards a cost effective strategy for cutinase production by a recombinant Saccharomyces cerevisiae: strain physiological aspects. Appl Microbiol Biotechnol 61(1):69-76
-
(2003)
Appl Microbiol Biotechnol
, vol.61
, Issue.1
, pp. 69-76
-
-
Ferreira, B.1
Calado, C.2
Van Keulen, F.3
Fonseca, L.4
Cabral, J.5
Da Fonseca, M.6
-
10
-
-
74549181271
-
Tuning microbial hosts for membrane protein production
-
20040113 10.1186/1475-2859-8-69
-
Freigassner M, Pichler H, Glieder A (2009) Tuning microbial hosts for membrane protein production. Microb Cell Fact 8(1):69
-
(2009)
Microb Cell Fact
, vol.8
, Issue.1
, pp. 69
-
-
Freigassner, M.1
Pichler, H.2
Glieder, A.3
-
11
-
-
0027587889
-
Continuous, high level production and excretion of a plasmid-encoded protein by Escherichia coli in a two-stage chemostat
-
18601275 10.1002/bit.260411004 1:CAS:528:DyaK3sXisFegsb0%3D
-
Fu J, Wilson DB, Shuler ML (1993) Continuous, high level production and excretion of a plasmid-encoded protein by Escherichia coli in a two-stage chemostat. Biotechnol Bioeng 41(10):937-946
-
(1993)
Biotechnol Bioeng
, vol.41
, Issue.10
, pp. 937-946
-
-
Fu, J.1
Wilson, D.B.2
Shuler, M.L.3
-
12
-
-
0035808168
-
Genomic analysis of high-cell-density recombinant Escherichia coli fermentation and "cell conditioning" for improved recombinant protein yield
-
11084598 10.1002/1097-0290(20010105)72:1<85: AID-BIT12>3.0.CO;2-H 1:CAS:528:DC%2BD3MXitVOrtw%3D%3D
-
Gill R, DeLisa M, Valdes J, Bentley W (2001) Genomic analysis of high-cell-density recombinant Escherichia coli fermentation and "cell conditioning" for improved recombinant protein yield. Biotechnol Bioeng 72(1):85-95
-
(2001)
Biotechnol Bioeng
, vol.72
, Issue.1
, pp. 85-95
-
-
Gill, R.1
Delisa, M.2
Valdes, J.3
Bentley, W.4
-
13
-
-
33646397008
-
Production of soluble and active transferrin receptor-targeting single-chain antibody using Saccharomyces cerevisiae
-
16550469 10.1007/s11095-006-9778-7 1:CAS:528:DC%2BD28XktFWjsb8%3D
-
Hackel BJ, Huang D, Bubolz JC, Wang XX, Shusta EV (2006) Production of soluble and active transferrin receptor-targeting single-chain antibody using Saccharomyces cerevisiae. Pharm Res 23(4):790-797
-
(2006)
Pharm Res
, vol.23
, Issue.4
, pp. 790-797
-
-
Hackel, B.J.1
Huang, D.2
Bubolz, J.C.3
Wang, X.X.4
Shusta, E.V.5
-
14
-
-
0027551848
-
Recombinant protein production via fed-batch culture of the yeast Saccharomyces cerevisiae
-
7763453 10.1016/0141-0229(93)90035-Z 1:CAS:528:DyaK3sXhtVSntLg%3D
-
Hardjito L, Greenfield PF, Lee PL (1993) Recombinant protein production via fed-batch culture of the yeast Saccharomyces cerevisiae. Enzyme Microb Technol 15(2):120-126
-
(1993)
Enzyme Microb Technol
, vol.15
, Issue.2
, pp. 120-126
-
-
Hardjito, L.1
Greenfield, P.F.2
Lee, P.L.3
-
15
-
-
69249103011
-
Modulating proteostasis: Peptidomimetic inhibitors and activators of protein folding
-
19601846 10.2174/138161209788682343 1:CAS:528:DC%2BD1MXos1altL0%3D
-
Hatahet F, Ruddock LW (2009) Modulating proteostasis: peptidomimetic inhibitors and activators of protein folding. Curr Pharm Des 15(21):2488-2507
-
(2009)
Curr Pharm des
, vol.15
, Issue.21
, pp. 2488-2507
-
-
Hatahet, F.1
Ruddock, L.W.2
-
16
-
-
4444265582
-
Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death
-
15350220 10.1016/j.molcel.2004.08.025 1:CAS:528:DC%2BD2cXnvFyhs7w%3D
-
Haynes CM, Titus EA, Cooper AA (2004) Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death. Mol Cell 15(5):767-776
-
(2004)
Mol Cell
, vol.15
, Issue.5
, pp. 767-776
-
-
Haynes, C.M.1
Titus, E.A.2
Cooper, A.A.3
-
17
-
-
0034518308
-
Kinetics of heat-shock response and inclusion body formation during temperature-induced production of basic fibroblast growth factor in high-cell-density cultures of recombinant Escherichia coli
-
11101327 10.1021/bp0000959 1:CAS:528:DC%2BD3cXntVehtbk%3D
-
Hoffmann F, Rinas U (2000) Kinetics of heat-shock response and inclusion body formation during temperature-induced production of basic fibroblast growth factor in high-cell-density cultures of recombinant Escherichia coli. Biotechnol Prog 16(6):1000-1007
-
(2000)
Biotechnol Prog
, vol.16
, Issue.6
, pp. 1000-1007
-
-
Hoffmann, F.1
Rinas, U.2
-
18
-
-
84862781268
-
Engineering of vesicle trafficking improves heterologous protein secretion in Saccharomyces cerevisiae
-
22265825 10.1016/j.ymben.2012.01.002 1:CAS:528:DC%2BC38XjtlOqu7w%3D
-
Hou J, Tyo K, Liu Z, Petranovic D, Nielsen J (2012a) Engineering of vesicle trafficking improves heterologous protein secretion in Saccharomyces cerevisiae. Metab Eng 14(2):120-127
-
(2012)
Metab Eng
, vol.14
, Issue.2
, pp. 120-127
-
-
Hou, J.1
Tyo, K.2
Liu, Z.3
Petranovic, D.4
Nielsen, J.5
-
19
-
-
84863629890
-
Metabolic engineering of recombinant protein production by Saccharomyces cerevisiae
-
22533807 10.1111/j.1567-1364.2012.00810.x 1:CAS:528:DC%2BC38XhtFegtL7O
-
Hou J, Tyo K, Liu Z, Petranovic D, Nielsen J (2012b) Metabolic engineering of recombinant protein production by Saccharomyces cerevisiae. FEMS Yeast Res 12(5):491-510
-
(2012)
FEMS Yeast Res
, vol.12
, Issue.5
, pp. 491-510
-
-
Hou, J.1
Tyo, K.2
Liu, Z.3
Petranovic, D.4
Nielsen, J.5
-
20
-
-
77249147339
-
Engineering of protein secretion in yeast: Strategies and impact on protein production
-
20140428 10.1007/s00253-010-2447-0 1:CAS:528:DC%2BC3cXit1amsb0%3D
-
Idiris A, Tohda H, Kumagai H, Takegawa K (2010) Engineering of protein secretion in yeast: strategies and impact on protein production. Appl Microbiol Biotechnol 86(2):403-417
-
(2010)
Appl Microbiol Biotechnol
, vol.86
, Issue.2
, pp. 403-417
-
-
Idiris, A.1
Tohda, H.2
Kumagai, H.3
Takegawa, K.4
-
21
-
-
84857058761
-
A systems-level approach for metabolic engineering of yeast cell factories
-
22188344 10.1111/j.1567-1364.2011.00779.x 1:CAS:528:DC%2BC38XjsV2gur0%3D
-
Kim IK, Roldão A, Siewers V, Nielsen J (2012) A systems-level approach for metabolic engineering of yeast cell factories. FEMS Yeast Res 12(2):228-248
-
(2012)
FEMS Yeast Res
, vol.12
, Issue.2
, pp. 228-248
-
-
Kim, I.K.1
Roldão, A.2
Siewers, V.3
Nielsen, J.4
-
22
-
-
84859037792
-
Biomanufacturing outsourcing outlook
-
Langer ES (2012) Biomanufacturing outsourcing outlook. BioPharm International 25(2):15-16
-
(2012)
BioPharm International
, vol.25
, Issue.2
, pp. 15-16
-
-
Langer, E.S.1
-
23
-
-
84862807811
-
Different expression systems for production of recombinant proteins in Saccharomyces cerevisiae
-
22179756 10.1002/bit.24409 1:CAS:528:DC%2BC38XnvVagsg%3D%3D
-
Liu Z, Tyo K, Martínez J, Petranovic D, Nielsen J (2012) Different expression systems for production of recombinant proteins in Saccharomyces cerevisiae. Biotechnol Bioeng 109(5):1259-1268
-
(2012)
Biotechnol Bioeng
, vol.109
, Issue.5
, pp. 1259-1268
-
-
Liu, Z.1
Tyo, K.2
Martínez, J.3
Petranovic, D.4
Nielsen, J.5
-
24
-
-
79956307251
-
Stampy: A statistical algorithm for sensitive and fast mapping of Illumina sequence reads
-
20980556 10.1101/gr.111120.110 1:CAS:528:DC%2BC3MXnsFylsrs%3D
-
Lunter G, Goodson M (2011) Stampy: A statistical algorithm for sensitive and fast mapping of Illumina sequence reads. Genome Res 21(6):936-939
-
(2011)
Genome Res
, vol.21
, Issue.6
, pp. 936-939
-
-
Lunter, G.1
Goodson, M.2
-
25
-
-
0036199670
-
Transcription factors regulating the response to oxidative stress in yeast
-
10.1089/152308602753625915 1:CAS:528:DC%2BD38XlsFChsbw%3D
-
Moye-Rowley WS (2002) Transcription factors regulating the response to oxidative stress in yeast. Antioxid Redox Sign 4(1):123-140
-
(2002)
Antioxid Redox Sign
, vol.4
, Issue.1
, pp. 123-140
-
-
Moye-Rowley, W.S.1
-
26
-
-
0026667524
-
Effect of growth rate on stability and gene expression of a recombinant plasmid during continuous culture of Escherichia coli in a non-selective medium
-
10.1007/BF01021635 1:CAS:528:DyaK38XmtFSks7g%3D
-
Nancib N, Boudrant J (1992) Effect of growth rate on stability and gene expression of a recombinant plasmid during continuous culture of Escherichia coli in a non-selective medium. Biotechnol Lett 14(8):643-648
-
(1992)
Biotechnol Lett
, vol.14
, Issue.8
, pp. 643-648
-
-
Nancib, N.1
Boudrant, J.2
-
27
-
-
0041858096
-
Systems biology: Understanding cells
-
12931164 10.1038/424883a 1:CAS:528:DC%2BD3sXmsV2isr0%3D
-
Nurse P (2003) Systems biology: understanding cells. Nature 424(6951):883-883
-
(2003)
Nature
, vol.424
, Issue.6951
, pp. 883-883
-
-
Nurse, P.1
-
28
-
-
41049102359
-
Architecture of transcriptional regulatory circuits is knitted over the topology of bio-molecular interaction networks
-
18261202 10.1186/1752-0509-2-17
-
Oliveira AP, Patil KR, Nielsen J (2008) Architecture of transcriptional regulatory circuits is knitted over the topology of bio-molecular interaction networks. BMC Syst Biol 2(1):17
-
(2008)
BMC Syst Biol
, vol.2
, Issue.1
, pp. 17
-
-
Oliveira, A.P.1
Patil, K.R.2
Nielsen, J.3
-
29
-
-
34248213118
-
Development of stable flocculent Saccharomyces cerevisiae strain for continuous Aspergillus niger beta-galactosidase production
-
10.1263/jbb.103.318 17502272 10.1263/jbb.103.318 1:CAS:528: DC%2BD2sXmslOqtr8%3D
-
Oliveira C, Teixeira JA, Lima N, Da Silva NA, Domingues L (2007) Development of stable flocculent Saccharomyces cerevisiae strain for continuous Aspergillus niger beta-galactosidase production. J Biosci Bioeng 103(4):318-324. doi: 10.1263/jbb.103.318
-
(2007)
J Biosci Bioeng
, vol.103
, Issue.4
, pp. 318-324
-
-
Oliveira, C.1
Teixeira, J.A.2
Lima, N.3
Da Silva, N.A.4
Domingues, L.5
-
30
-
-
14544268137
-
Uncovering transcriptional regulation of metabolism by using metabolic network topology
-
10.1073/pnas.0406811102 1:CAS:528:DC%2BD2MXitVSksro%3D
-
Patil KR, Nielsen J (2005) Uncovering transcriptional regulation of metabolism by using metabolic network topology. Proc Nati Acad Sci USA 102(8):2685-2689
-
(2005)
Proc Nati Acad Sci USA
, vol.102
, Issue.8
, pp. 2685-2689
-
-
Patil, K.R.1
Nielsen, J.2
-
31
-
-
77955023666
-
BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response
-
10.1371/journal.pbio.1000415 20625545 10.1371/journal.pbio.1000415
-
Pincus D, Chevalier MW, Aragón T, Van Anken E, Vidal SE, El-Samad H, Walter P (2010) BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response. PLoS Biol 8(7):e1000415. doi: 10.1371/journal.pbio.1000415
-
(2010)
PLoS Biol
, vol.8
, Issue.7
, pp. 1000415
-
-
Pincus, D.1
Chevalier, M.W.2
Aragón, T.3
Van Anken, E.4
Vidal, S.E.5
El-Samad, H.6
Walter, P.7
-
32
-
-
33845935641
-
Growth-rate regulated genes have profound impact on interpretation of transcriptome profiling in Saccharomyces cerevisiae
-
17105650 10.1186/gb-2006-7-11-r107
-
Regenberg B, Grotkjær T, Winther O, Fausbøll A, Åkesson M, Bro C, Hansen LK, Brunak S, Nielsen J (2006) Growth-rate regulated genes have profound impact on interpretation of transcriptome profiling in Saccharomyces cerevisiae. Genome Biol 7(11):R107
-
(2006)
Genome Biol
, vol.7
, Issue.11
, pp. 107
-
-
Regenberg, B.1
Grotkjær, T.2
Winther, O.3
Fausbøll, A.4
Åkesson, M.5
Bro, C.6
Hansen, L.K.7
Brunak, S.8
Nielsen, J.9
-
33
-
-
37649013169
-
Engineering eukaryotic protein factories
-
17885737 10.1007/s10529-007-9524-1
-
Schröder M (2008) Engineering eukaryotic protein factories. Biotechnol Lett 30(2):187-196
-
(2008)
Biotechnol Lett
, vol.30
, Issue.2
, pp. 187-196
-
-
Schröder, M.1
-
34
-
-
82755162477
-
The impact of phosphate scarcity on pharmaceutical protein production in S. cerevisiae: Linking transcriptomic insights to phenotypic responses
-
10.1186/1475-2859-10-104 1:CAS:528:DC%2BC38Xitleiu78%3D
-
Seresht AK, Palmqvist EA, Olsson L (2011) The impact of phosphate scarcity on pharmaceutical protein production in S. cerevisiae: linking transcriptomic insights to phenotypic responses. Microb Cell Fact 10(1):104
-
(2011)
Microb Cell Fact
, vol.10
, Issue.1
, pp. 104
-
-
Seresht, A.K.1
Palmqvist, E.A.2
Olsson, L.3
-
35
-
-
0033933125
-
ClpB and HtpG facilitate de novo protein folding in stressed Escherichia coli cells
-
10931286 10.1046/j.1365-2958.2000.01951.x 1:CAS:528:DC%2BD3cXlt1Gjur4%3D
-
Thomas JG, Baneyx F (2000) ClpB and HtpG facilitate de novo protein folding in stressed Escherichia coli cells. Mol Microbiol 36(6):1360-1370
-
(2000)
Mol Microbiol
, vol.36
, Issue.6
, pp. 1360-1370
-
-
Thomas, J.G.1
Baneyx, F.2
-
36
-
-
84863380845
-
Imbalance of heterologous protein folding and disulfide bond formation rates yields runaway oxidative stress
-
22380681 10.1186/1741-7007-10-16 1:CAS:528:DC%2BC38XlvF2gs74%3D
-
Tyo K, Liu Z, Petranovic D, Nielsen J (2012) Imbalance of heterologous protein folding and disulfide bond formation rates yields runaway oxidative stress. BMC Biol 10:16
-
(2012)
BMC Biol
, vol.10
, pp. 16
-
-
Tyo, K.1
Liu, Z.2
Petranovic, D.3
Nielsen, J.4
-
37
-
-
0342699643
-
From gene to product in yeast: Production of fungal cutinase
-
10862890 10.1016/S0141-0229(00)00176-9 1:CAS:528:DC%2BD3cXktFSjur4%3D
-
Verripsab T, Duboc P, Visser C, Sagt C (2000) From gene to product in yeast: production of fungal cutinase. Enzyme Microb Technol 26(9-10):812-818
-
(2000)
Enzyme Microb Technol
, vol.26
, Issue.9-10
, pp. 812-818
-
-
Verripsab, T.1
Duboc, P.2
Visser, C.3
Sagt, C.4
|