Methamphetamine induces autophagy as a pro-survival response against apoptotic endothelial cell death through the Kappa opioid receptor

Cell Death and Disease

Volumn 5, Issue 3, 2014, Pages

  Ma, J ^a   Wan, J ^a   Meng, J ^a   Banerjee, S ^a   Ramakrishnan, S ^a   Roy, S ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Autophagy; Cell death; Kappa opioid receptor; Methamphetamine

Indexed keywords

BECLIN 1; KAPPA OPIATE RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN; METHAMPHETAMINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B;

APOPTOSIS; ARTICLE; AUTOPHAGY; BLOOD BRAIN BARRIER; CELL SURVIVAL; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME INACTIVATION; HUMAN; HUMAN CELL; LONG TERM EXPOSURE; MICROVASCULAR ENDOTHELIAL CELL; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BLOOD-BRAIN BARRIER; CELL SURVIVAL; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM STIMULANTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENZYME ACTIVATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; METHAMPHETAMINE; MICROTUBULE-ASSOCIATED PROTEINS; MICROVESSELS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NARCOTIC ANTAGONISTS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, OPIOID, KAPPA; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TOR SERINE-THREONINE KINASES; TRANSFECTION;

EID: 84897390898     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.64     Document Type: Article

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