Fermenting soybeans with Bacillus licheniformis potentiates their capacity to improve cognitive function and glucose homeostaisis in diabetic rats with experimental Alzheimer’s type dementia

European Journal of Nutrition

Volumn 54, Issue 1, 2015, Pages 77-88

  Yang, Hye Jeong ^a   Kwon, Dae Young ^a   Kim, Hyun Jin ^b   Kim, Min Jung ^a   Jung, Do Yeon ^c   Kang, Hee Joo ^a   Kim, Da Sol ^d   Kang, Suna ^d   Moon, Na Rang ^d   Shin, Bae Keun ^d   Park, Sunmin ^d  

^a Korea Food Research Institute   (South Korea)

^b Gyeongsang National University   (South Korea)

^c Institute of Sunchang Fermented Soybean Products   (South Korea)

^d Hoseo University   (South Korea)

Author keywords

Alzheimer s disease; Cognitive function; Glucose homeostasis; Insulin secretion; Memory; Cell mass

Indexed keywords

ANTIDIABETIC AGENT; ISOFLAVONE DERIVATIVE; NOOTROPIC AGENT;

ALZHEIMER DISEASE; ANALYSIS; ANIMAL; BACILLUS; COMPARATIVE STUDY; COMPLICATION; DIET THERAPY; DISEASE MODEL; FERMENTATION; FOOD HANDLING; FUNCTIONAL FOOD; HIPPOCAMPUS; HUMAN; HYPERGLYCEMIA; INSULIN RESISTANCE; MALE; METABOLISM; MICROBIOLOGY; NERVE CELL; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET; PATHOLOGY; RANDOMIZATION; SECRETION (PROCESS); SOUTH KOREA; SOY FOOD; SPRAGUE DAWLEY RAT;

ALZHEIMER DISEASE; ANIMALS; BACILLUS; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; FERMENTATION; FOOD HANDLING; FUNCTIONAL FOOD; HIPPOCAMPUS; HUMANS; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; INSULIN RESISTANCE; ISLETS OF LANGERHANS; ISOFLAVONES; MALE; NEURONS; NOOTROPIC AGENTS; RANDOM ALLOCATION; RATS, SPRAGUE-DAWLEY; REPUBLIC OF KOREA; SOY FOODS;

EID: 84897353529     PISSN: 14366207     EISSN: 14366215     Source Type: Journal    
DOI: 10.1007/s00394-014-0687-y     Document Type: Article

References (31)

1. Rocca WA, Petersen RC, Knopman DS, Hebert LE, Evans DA, Hall KS et al (2011) Trends in the incidence and prevalence of Alzheimer’s disease, dementia, and cognitive impairment in the United States. Alzheimers Dement 7:80–93
2. Tang J, Pei Y, Zhou G (2013) When aging-onset diabetes is coming across with Alzheimer disease, comparable pathogenesis and therapy. Exp Gerontol 48:744–750
3. De Felice FG (2013) Alzheimer’s disease and insulin resistance: translating basic science into clinical applications. J Clin Invest 123:531–539
4. Park S, Kim DS, Kwon DY, Yang HJ (2011) Long-term central infusion of adiponectin improves energy and glucose homeostasis by decreasing fat storage and suppressing hepatic gluconeogenesis without changing food intake. J Neuroendocrinol 23:687–698
5. Kwon DY, Hong SM, Lee JE, Sung SR, Park S (2007) Long-term consumption of fermented soybean-derived chungkookjang attenuates hepatic insulin resistance in 90% pancreatectomized diabetic rats. Horm Metab Res 39:752–757
6. Kwon GH, Lee HA, Park JY, Kim JS, Lim J, Park CS et al (2009) Development of a RAPD-PCR method for identification of Bacillus species isolated from Cheonggukjang. Int J Food Microbiol 129:282–287
7. Yang HJ, Kim HJ, Kim MJ, Kang S, da Kim S, Daily JW et al (2013) Standardized chungkookjang, short-term fermented soybeans with Bacillus licheniformis, improves glucose homeostasis as much as traditionally made chungkookjang in diabetic rats. J Clin Biochem Nutr 52:49–57
8. Kang HJ, Yang HJ, Kim MJ, Han ES, Kim HJ, Kwon DY (2011) Metabolomic analysis of meju during fermentation by ultra-performance liquid chromatography-quadrupole-time of flight mass spectrometry. Food Chem 127:1056–1064
9. Hosokawa YA, Hosokawa H, Chen C, Leahy JL (1996) Mechanism of impaired glucose-potentiated insulin-secretion in diabetic 90 percent pancreatectomy rats-Study using glucagon-like peptide-1 (7–37). J Clin Invest 97:180–186
10. Yang HJ, Hwang JT, Kwon DY, Kim MJ, Kang S, Moon NR et al (2013) Yuzu extract prevents cognitive decline and impaired glucose homeostasis in β-amyloid-infused rats. J Nutr 143:1093–1099
11. Report of the American Institute of Nutrition (1997) Ad Hoc committee on standards for nutritional studies. J Nutr 107:1340–1348
12. Niwa H, Ogawa Y, Kido Y, Abe Y, Kobayashi M, Mori T et al (1989) The rate of lipid oxidation in septic rat models. Jpn J Surg 19:439–445
13. Kim JK, Kim YJ, Fillmore JJ, Chen Y, Moore I, Lee J et al (2001) Prevention of fat-induced insulin resistance by salicylate. J Clin Invest 108:437–446
14. Dobbins RL, Szczepaniak LS, Myhill J, Tamura Y, Uchino H, Giacca A et al (2002) The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats. Diabetes 51:1825–1833
15. Hsu RL, Lee KT, Wang JH, Lee LY, Chen RP (2009) Amyloid-degrading ability of nattokinase from Bacillus subtilis natto. J Agric Food Chem 57:503–508
16. Ding BJ, Ma WW, He LL, Zhou X, Yuan LH, Yu HL et al (2011) Soybean isoflavone alleviates β-amyloid 1-42 induced inflammatory response to improve learning and memory ability by down regulation of Toll-like receptor 4 expression and nuclear factor-κB activity in rats. Int J Dev Neurosci 29:537–542
17. Kato-Kataoka A, Sakai M, Ebina R, Nonaka C, Asano T, Miyamori T (2010) Soybean-derived phosphatidylserine improves memory function of the elderly Japanese subjects with memory complaints. J Clin Biochem Nutr 47:246–255
18. Suzuki S, Yamatoya H, Sakai M, Kataoka A, Furushiro M, Kudo S (2001) Oral administration of soybean lecithin transphosphatidylated phosphatidylserine improves memory impairment in aged rats. J Nutr 131:2951–2956
19. Kreijkamp-Kaspers S, Kok L, Grobbee DE, Grobbee DE, de Haan EH, Aleman A et al (2004) Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women: a randomized controlled trial. JAMA 292:65–74
20. Kwon DY, Jang JS, Hong SM, Lee JE, Sung SR, Park HR et al (2007) Long-term consumption of fermented soybean-derived chungkookjang enhances insulinotropic action unlike soybeans in 90% pancreatectomized diabetic rats. Eur J Nutr 46:44–52
21. Heras-Sandoval D, Ferrera P, Arias C (2012) Amyloid-β protein modulates insulin signaling in presynaptic terminals. Neurochem Res 37:1879–1885
22. Li L, Holscher C (2007) Common pathological processes in Alzheimer disease and type 2 diabetes: a review. Brain Res Rev 56:384–402
23. Baker LD, Cross DJ, Minoshima S, Belongia D, Watson GS, Craft S (2011) Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes. Arch Neurol 68:51–57
24. Hu YS, Long N, Pigino G, Brady ST, Lazarov O (2013) Molecular mechanisms of environmental enrichment, impairments in Akt/GSK3β, neurotrophin-3 and CREB signaling. PLoS ONE 8:e64460
25. Salkovic-Petrisic M, Osmanovic J, Grünblatt E, Riederer P, Hoyer S (2009) Modeling sporadic Alzheimer’s disease: the insulin resistant brain state generates multiple long-term morphobiological abnormalities including hyperphosphorylated tau protein and amyloid-beta. J Alzheimers Dis 18:729–750
26. Hurtado DE, Molina-Porcel L, Carroll JC, Macdonald C, Aboagye AK, Trojanowski JQ et al (2012) Selectively silencing GSK-3 isoforms reduces plaques and tangles in mouse models of Alzheimer’s disease. J Neurosci 32:7392–7402
27. Liu Y, Liu F, Grundke-Iqbal I, Iqbal K, Gong CX (2011) Deficient brain insulin signalling pathway in Alzheimer’s disease and diabetes. J Pathol 225:54–62
28. Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA (2011) Insulin-resistant brain state: the culprit in sporadic Alzheimer’s disease? Ageing Res Rev 10:264–273
29. Zhong Y, Miao Y, Jia WP, Yan H, Wang BY, Jin J (2012) Hyperinsulinemia, insulin resistance and cognitive decline in older cohort. Biomed Environ Sci 25:8–14
30. Calegari VC, Torsoni AS, Vanzela EC, Araújo EP, Morari J, Zoppi CC et al (2011) Inflammation of the hypothalamus leads to defective pancreatic islet function. J Biol Chem 286:12870–12880
31. Park S, Ahn IS, Kim DS (2010) Central infusion of leptin improves insulin resistance and suppresses beta-cell function, but not beta-cell mass, primarily through the sympathetic nervous system in a type 2 diabetic rat model. Life Sci 86:854–862