Induction of brain CYP2E1 by chronic ethanol treatment and related oxidative stress in hippocampus, cerebellum, and brainstem

Toxicology

Volumn 302, Issue 2-3, 2012, Pages 275-284

  Zhong, Yanjun ^a   Dong, Guicheng ^b   Luo, Haiguang ^a   Cao, Jie ^a   Wang, Chang ^a   Wu, Jianyuan ^c   Feng, Yu Qi ^c   Yue, Jiang ^a  

^a WUHAN UNIVERSITY   (China)

^b INNER MONGOLIA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c WUHAN UNIVERSITY   (China)

Author keywords

Brain; Cytochrome P450 2E1; Ethanol; Reactive oxygen species

Indexed keywords

6 HYDROXYCHLORZOXAZONE; ALCOHOL; CYTOCHROME P450 2E1; LACTATE DEHYDROGENASE; QUANTUM DOT; REACTIVE OXYGEN METABOLITE; CHLORZOXAZONE; MESSENGER RNA;

ADULT; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN MEMBRANE; BRAIN REGION; BRAIN STEM; CATALYSIS; CELLULAR DISTRIBUTION; CEREBELLUM; CHEMICAL ANALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; FRONTAL CORTEX; GENE EXPRESSION; HIPPOCAMPUS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NEUROBLASTOMA CELL; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPE; SCANNING ELECTRON MICROSCOPY; WHITE MATTER; ANIMAL; CONFOCAL MICROSCOPY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; NEUROBLASTOMA; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL LINE; UPREGULATION; WISTAR RAT;

RATTUS NORVEGICUS;

ANIMALS; BRAIN STEM; CELL LINE, TUMOR; CEREBELLUM; CHLORZOXAZONE; CYTOCHROME P-450 CYP2E1; ETHANOL; HIPPOCAMPUS; HUMANS; L-LACTATE DEHYDROGENASE; MALE; MICROSCOPY, CONFOCAL; NEUROBLASTOMA; OXIDATIVE STRESS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; UP-REGULATION;

EID: 84897122600     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2012.08.009     Document Type: Article

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