Distribution and differential induction of CYP2E1 by ethanol and acetone in the mesocorticolimbic system of rat

Alcohol and Alcoholism

Volumn 43, Issue 4, 2008, Pages 401-407

  Sánchez Catalán, M José ^a   Hipólito, Lucía ^a   Guerri, Consuelo ^b   Granero, Luis ^a   Polache, Ana ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONE; ALCOHOL; CYTOCHROME P450 2E1; DRINKING WATER;

ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DRUG DEPENDENCE; ENZYME INDUCTION; ENZYME LOCALIZATION; FEEDING; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; VENTRAL TEGMENTUM; WESTERN BLOTTING;

ACETONE; ALCOHOLISM; ANIMALS; BEHAVIOR, ADDICTIVE; BLOTTING, WESTERN; CYTOCHROME P-450 CYP2E1; ETHANOL; LIMBIC SYSTEM; MALE; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; RATS; RATS, WISTAR;

RATTUS;

EID: 47049086815     PISSN: 07350414     EISSN: 14643502     Source Type: Journal    
DOI: 10.1093/alcalc/agn012     Document Type: Article

References (33)

1. Anandatheerthavarada, H. K., Shankar, S. K., Bhamre, S., Boyd, M. R., Song, B. J. and Ravindranath, V. (1993) Induction of brain cytochrome P-450IIE1 by chronic ethanol treatment. Brain Research 601 279-85.
2. Collins, M. (1985) Aldehyde Adducts in Alcoholism. New York: Alan Liss.
3. Forkert, P. G., Massey, T. E., Jones, A. B., Park, S. S., Gelboin, H. V. and Anderson, L. M. (1991) Distribution of cytochrome CYP2E1 in murine liver after ethanol and acetone administration: Carcinogenesis 12:2259-68.
4. Gonzales, R. A., Job, M. O. and Doyon, W. M. (2004). The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement. Pharmacology & Therapeutics 103:121-46.
5. Haber, H., Winkle, A., Putscher, I. et al. (1996) Plasma and urine salsolinol in humans: Effect of acute ethanol intake on the enantiomeric composition of salsolinol. Alcoholism: Clinical and Experimental Research 20:87-92.
6. Hansson, T., Tindberg, N., Ingelman-Sundberg, M. and Kohler, C. (1990) Regional distribution of ethanol-inducible cytochrome P450 IIE1 in the rat central nervous system. Neuroscience 34:451-63.
7. Hipólito, L., Sánhez, M. J., Polache, A. and Granero, L. (2007) Brain metabolism of ethanol and alcoholism: An update. Current Drug Metabolism 8:716-27.
8. Howard, L. A., Miksys, S., Hoffmann, E., Mash, D. and Tyndale, R. F. (2003) Brain CYP92E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics. British Journal of Pharmacology 138:1376-86.
9. Hyrrian, S. E. and Malenka, R. C. (2001) Addiction and the brain: The neurobiology of compulsion and its persistence. Nature Reviews Neuroscience 2:695-703.
10. Joshi, M. and Tyndale, R. F. (2006) Regional and cellular distribution of CYP2E1 in monkey brain and its induction by chronic nicotine. Neuropharmacology 50:568-75.
11. Kapoor, N., Pant, A. B., Dhawan, A. et al. (2006) Differences in sensitivity of cultured rat brain neuronal and glial cytochrome P450 2E1 to ethanol. Life Sciences 79:1514-22.
12. Koob, G. F. and Le Moal, M. (2006), Neurobiology of Addiction. New York: Academic Press.
13. Koop, D. R., Crump, B. L., Nordblom, G. D. and Coon, M. J. (1985) Immunochemical evidence for induction of the alcohol-oxidizing cytochrome P-450 of rabbit liver microsomes by diverse agents: Ethanol, imidazole, trichloroethylene, acetone, pyrazole, and isoniazid. Proceedings of the National Academy of Sciences of the United States of America 82:4065-9.
14. Koop, D. R. (1992) Oxidative and reductive metabolism by cytochrome P-4502E1. Federation of American Societies for Experimental Biology Journal 6:724-30.
15. Le, A. D. and Israel, Y. (1994) A simple technique for quantifying intoxication-induced by low doses of ethanol. Pharmacology, Biochemistry, and Behavior 48:229-34.
16. Montoliu, C., Vallés, S., Renau-Piqueras, J. and Guerri, C. (1994) Ethanol-induced oxygen radical formation and lipid peroxidation in rat brain: Effect of chronic alcohol consumption. Journal of Neurochemistry 63:1855-62.
17. Montoliu, C., Sancho-Tello, M., Azorin, I. et al. (1995) Ethanol increases cytochrome P4502E1 and induces oxidative stress in astrocytes. Journal of Neurochemistry 65:2561-70.
18. Myers, R. D. (1996) Tetrahydroisoquinolines and alcoholism: Where are we today? Alcoholism, Clinical and Experimental Research 20 498-500.
19. Paxinos, G. and Watson, C. (1986) The Rat Brain in Stereotaxic Coordinates. New York: Academic Press.
20. Quertemont, E., Tambour, S. and Tirelli, E. (2005) The role of acetaldehyde in the neurobehavioral effects of ethanol: A comprehensive review of animal studies. Progress in Neurobiology 75:247-74.
21. Riedl, A. G., Watts, P. M., Edwards, R. J., Boobis, A. R., Jenner, P. and Marsden, C. D. (1996) Selective localisation of P450 enzymes and NADPH-P450 oxidoreductase in rat basal ganglia using anti-peptide antisera. Brain Research 743:324-8.
22. Roberts, B. J., Shoaf, S. E., Jeong, K. S. and Song, B. J. (1994) Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: Evidence that CYPE1 possesses a rapid phase half-life of 6 hours or less. Biochemical and Biophysical Research Communications 205:1064-71.
23. Rodd, Z. A., Bell, R. L., Zhang, Y. et al. (2003) Salsolinol produces reinforcing effects in the nucleus accumbens shell of alcohol-preferring (P) rats. Alcoholism, Clinical and Experimental Research 27:440-9.
24. Rodd-Henricks, Z. A., Melendez, R. I., Zaffaroni, A., Goldstein, A., McBride, W. J. and Li, T. K. (2002) The reinforcing effects of acetaldehyde in the posterior ventral tegmental area of alcohol-preferring rats. Pharmacology, Biochemistry, and Behavior 72:55-64.
25. Sjoquist, B., Eriksson, A. and Winblad, B. (1982a) Brain salsolinol levels in alcoholism. Lancet 1:675-6.
26. Sjoquist, B., Liljequist, S. and Engel, J. (1982b) Increased salsolinol levels in rat striatum and limbic forebrain following chronic ethanol treatment. Journal of Neurochemistry 39:259-62.
27. Tindberg, N. and Ingelman-Sundberg, M. (1996) Expression, catalytic activity, and inducibility of cytochrome P450 2E1 (CYP2E1) in the rat central nervous-system. Journal of Neurochemistry 67:2066-73.
28. Upadhya, S. C., Tirumalai, P. S., Boyd, M. R., Mori, T. and Ravindranath, V. (2000) Cytochrome P4502E (CYP2E) in brain: Constitutive expression, induction by ethanol and localization by fluorescence in situ hybridization. Archives of Biochemistry and Biophysics 373 23-34.
29. Warner, M. and Gustafsson, J. A. (1994) Effect of ethanol on cytochrome P450 in the rat brain. Proceedings of the National Academy of Sciences of the United States of America 91:1019-23.
30. Wise, R. A. and Rompre, P. P. (1989) Brain dopamine and reward. Annual Review of Psychology 40:191-225.
31. Yadav, S., Dhawan, A., Singh, R. L., Seth, P. K. and Parmar, D. (2006) Expression of constitutive and inducible cytochrome P450 2E1 in rat brain. Molecular and Cellular Biochemistry 286:171-80.
32. Yang, C. S., Yoo, J. S., Ishizaki, H. and Hong, J. Y. (1990) Cytochrome P450IIE1: Roles in nitrosamine metabolism and mechanisms of regulation. Drug Metabolism Reviews 22:147-59.
33. Zimatkin, S. M., Pronko, S. P., Vasiliou, V., Gonzalez, F. J. and Deitrich, R. A. (2006) Enzymatic mechanisms of ethanol oxidation in the brain. Alcoholism, Clinical and Experimental Research 30 1500-5.