Acetyl-l-carnitine protects neuronal function from alcohol-induced oxidative damage in the brain

Free Radical Biology and Medicine

Volumn 49, Issue 10, 2010, Pages 1494-1504

  Rump, Travis J ^a   Muneer, P M Abdul ^a   Szlachetka, Adam M ^a   Lamb, Allyson ^a   Haorei, Catherine ^a   Alikunju, Saleena ^a   Xiong, Huangui ^a   Keblesh, James ^a   Liu, Jianuo ^a   Zimmerman, Matthew C ^a   Jones, Jocelyn ^a   Donohue, Terrence M ^b   Persidsky, Yuri ^c   Haorah, James ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b VA NEBRASKA WESTERN IOWA HEALTH CARE SYSTEM   (United States)

^c TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acetyl l carnitine; Alcohol induced oxidative damage; Astrogliosis; Free radicals; Neurodegeneration; Synaptic neurotransmission

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; ALCOHOL; INDUCIBLE NITRIC OXIDE SYNTHASE; LEVACECARNINE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UBIDECARENONE;

ALCOHOL CONSUMPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOSIS; BRAIN CELL; BRAIN DAMAGE; BRAIN FUNCTION; BRAIN REGION; BRAIN TISSUE; CELL LOSS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVATION; EXCITATORY POSTSYNAPTIC POTENTIAL; FRONTAL CORTEX; GLIA CELL; HISTOPATHOLOGY; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; LONG TERM POTENTIATION; MALE; MICROGLIA; MOUSE; NERVE CELL; NERVE DEGENERATION; NEUROPROTECTION; NEUROTRANSMISSION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION; WESTERN BLOTTING;

ACETYLCARNITINE; ALDEHYDES; ANIMALS; ASTROCYTES; BRAIN; ETHANOL; LONG-TERM POTENTIATION; MALE; MICE; MICE, INBRED C57BL; NADH, NADPH OXIDOREDUCTASES; NEURONS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE TYPE II; SYNAPTIC TRANSMISSION; TYROSINE;

ANIMALIA; MUS;

EID: 77957763375     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.08.011     Document Type: Article

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