메뉴 건너뛰기




Volumn 609, Issue 1-3, 2009, Pages 88-95

Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake

Author keywords

Alcohol; Cytochrome P450 2B1 2; Cytochrome P450 2E1; Ethanol self administration; Nicotine

Indexed keywords

ALCOHOL; CYTOCHROME P450 2B1; CYTOCHROME P450 2B2; CYTOCHROME P450 2D1; CYTOCHROME P450 2E1; NICOTINE;

EID: 64549154408     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.03.015     Document Type: Article
Times cited : (28)

References (69)
  • 1
    • 0018904435 scopus 로고
    • Effect of ethanol pretreatment on the pharmacokinetics of nicotine in rats
    • Adir J., Wildfeuer W., and Miller R.P. Effect of ethanol pretreatment on the pharmacokinetics of nicotine in rats. J. Pharmacol. Exp. Ther. 212 (1980) 274-279
    • (1980) J. Pharmacol. Exp. Ther. , vol.212 , pp. 274-279
    • Adir, J.1    Wildfeuer, W.2    Miller, R.P.3
  • 2
    • 0029046313 scopus 로고
    • Relationship between alcohol and tobacco dependencies among alcoholics who smoke
    • Batel P., Pessione F., Maitre C., and Rueff B. Relationship between alcohol and tobacco dependencies among alcoholics who smoke. Addiction 90 (1995) 977-980
    • (1995) Addiction , vol.90 , pp. 977-980
    • Batel, P.1    Pessione, F.2    Maitre, C.3    Rueff, B.4
  • 3
    • 0021270837 scopus 로고
    • Daily intake of nicotine during cigarette smoking
    • Benowitz N.L., and Jacob III P. Daily intake of nicotine during cigarette smoking. Clin. Pharmacol. Ther. 35 (1984) 499-504
    • (1984) Clin. Pharmacol. Ther. , vol.35 , pp. 499-504
    • Benowitz, N.L.1    Jacob III, P.2
  • 5
    • 0030608347 scopus 로고    scopus 로고
    • Voluntary ethanol intake in the rat: effects of nicotinic acetylcholine receptor blockade or subchronic nicotine treatment
    • Blomqvist O., Ericson M., Johnson D.H., Engel J.A., and Soderpalm B. Voluntary ethanol intake in the rat: effects of nicotinic acetylcholine receptor blockade or subchronic nicotine treatment. Eur. J. Pharmacol. 314 (1996) 257-267
    • (1996) Eur. J. Pharmacol. , vol.314 , pp. 257-267
    • Blomqvist, O.1    Ericson, M.2    Johnson, D.H.3    Engel, J.A.4    Soderpalm, B.5
  • 6
    • 0031472449 scopus 로고    scopus 로고
    • Opposite effects of Ro 15-4513 on acquisition and maintenance of ethanol drinking behavior in male Wistar rats
    • Buczek Y., Tomkins D.M., Le A.D., and Sellers E.M. Opposite effects of Ro 15-4513 on acquisition and maintenance of ethanol drinking behavior in male Wistar rats. Alcohol Clin. Exp. Res. 21 (1997) 1667-1675
    • (1997) Alcohol Clin. Exp. Res. , vol.21 , pp. 1667-1675
    • Buczek, Y.1    Tomkins, D.M.2    Le, A.D.3    Sellers, E.M.4
  • 7
    • 1342323673 scopus 로고    scopus 로고
    • Oxidative stress, toxicology, and pharmacology of CYP2E1
    • Caro A.A., and Cederbaum A.I. Oxidative stress, toxicology, and pharmacology of CYP2E1. Annu. Rev. Pharmacol. Toxicol. 44 (2004) 27-42
    • (2004) Annu. Rev. Pharmacol. Toxicol. , vol.44 , pp. 27-42
    • Caro, A.A.1    Cederbaum, A.I.2
  • 8
    • 0027369366 scopus 로고
    • Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes
    • Chang T.K., Weber G.F., Crespi C.L., and Waxman D.J. Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes. Cancer Res. 53 (1993) 5629-5637
    • (1993) Cancer Res. , vol.53 , pp. 5629-5637
    • Chang, T.K.1    Weber, G.F.2    Crespi, C.L.3    Waxman, D.J.4
  • 9
    • 0034969503 scopus 로고    scopus 로고
    • Chronic infusion of nicotine can increase operant self-administration of alcohol
    • Clark A., Lindgren S., Brooks S.P., Watson W.P., and Little H.J. Chronic infusion of nicotine can increase operant self-administration of alcohol. Neuropharmacology 41 (2001) 108-117
    • (2001) Neuropharmacology , vol.41 , pp. 108-117
    • Clark, A.1    Lindgren, S.2    Brooks, S.P.3    Watson, W.P.4    Little, H.J.5
  • 10
    • 0020700952 scopus 로고
    • The effects of nicotine on locomotor activity in non-tolerant and tolerant rats
    • Clarke P.B., and Kumar R. The effects of nicotine on locomotor activity in non-tolerant and tolerant rats. Br. J. Pharmacol. 78 (1983) 329-337
    • (1983) Br. J. Pharmacol. , vol.78 , pp. 329-337
    • Clarke, P.B.1    Kumar, R.2
  • 11
    • 0027991930 scopus 로고
    • Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area
    • Corrigall W.A., Coen K.M., and Adamson K.L. Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area. Brain Res. 653 (1994) 278-284
    • (1994) Brain Res. , vol.653 , pp. 278-284
    • Corrigall, W.A.1    Coen, K.M.2    Adamson, K.L.3
  • 14
    • 0023854490 scopus 로고
    • Ligand-dependent maintenance of ethanol-inducible cytochrome P-450 in primary rat hepatocyte cell cultures
    • Eliasson E., Johansson I., and Ingelman-Sundberg M. Ligand-dependent maintenance of ethanol-inducible cytochrome P-450 in primary rat hepatocyte cell cultures. Biochem. Biophys. Res. Commun. 150 (1988) 436-443
    • (1988) Biochem. Biophys. Res. Commun. , vol.150 , pp. 436-443
    • Eliasson, E.1    Johansson, I.2    Ingelman-Sundberg, M.3
  • 15
    • 21344469970 scopus 로고    scopus 로고
    • The genetics of addictions: uncovering the genes
    • Goldman D., Oroszi G., and Ducci F. The genetics of addictions: uncovering the genes. Nat. Rev., Genet. 6 (2005) 521-532
    • (2005) Nat. Rev., Genet. , vol.6 , pp. 521-532
    • Goldman, D.1    Oroszi, G.2    Ducci, F.3
  • 16
    • 10444229539 scopus 로고    scopus 로고
    • Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1
    • Gonzalez F.J. Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1. Mutat. Res. 569 (2005) 101-110
    • (2005) Mutat. Res. , vol.569 , pp. 101-110
    • Gonzalez, F.J.1
  • 17
    • 4444300234 scopus 로고    scopus 로고
    • The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement
    • Gonzales R.A., Job M.O., and Doyon W.M. The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement. Pharmacol. Ther. 103 (2004) 121-146
    • (2004) Pharmacol. Ther. , vol.103 , pp. 121-146
    • Gonzales, R.A.1    Job, M.O.2    Doyon, W.M.3
  • 19
    • 1942531624 scopus 로고    scopus 로고
    • Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes
    • Hesse L.M., He P., Krishnaswamy S., Hao Q., Hogan K., von Moltke L.L., Greenblatt D.J., and Court M.H. Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes. Pharmacogenetics 14 (2004) 225-238
    • (2004) Pharmacogenetics , vol.14 , pp. 225-238
    • Hesse, L.M.1    He, P.2    Krishnaswamy, S.3    Hao, Q.4    Hogan, K.5    von Moltke, L.L.6    Greenblatt, D.J.7    Court, M.H.8
  • 20
    • 0036449402 scopus 로고    scopus 로고
    • Potentiation of 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123)-induced liver toxicity by ethanol in guinea-pigs
    • Hoet P., Buchet J.P., Sempoux C., Haufroid V., Rahier J., and Lison D. Potentiation of 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123)-induced liver toxicity by ethanol in guinea-pigs. Arch. Toxicol. 76 (2002) 707-714
    • (2002) Arch. Toxicol. , vol.76 , pp. 707-714
    • Hoet, P.1    Buchet, J.P.2    Sempoux, C.3    Haufroid, V.4    Rahier, J.5    Lison, D.6
  • 21
    • 0034756293 scopus 로고    scopus 로고
    • Low doses of nicotine and ethanol induce CYP2E1 and chlorzoxazone metabolism in rat liver
    • Howard L.A., Micu A.L., Sellers E.M., and Tyndale R.F. Low doses of nicotine and ethanol induce CYP2E1 and chlorzoxazone metabolism in rat liver. J. Pharmacol. Exp. Ther. 299 (2001) 542-550
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , pp. 542-550
    • Howard, L.A.1    Micu, A.L.2    Sellers, E.M.3    Tyndale, R.F.4
  • 22
    • 33645109957 scopus 로고    scopus 로고
    • Induction and recovery time course of rat brain CYP2E1 after nicotine treatment
    • Joshi M., and Tyndale R.F. Induction and recovery time course of rat brain CYP2E1 after nicotine treatment. Drug Metab. Dispos. 34 (2006) 647-652
    • (2006) Drug Metab. Dispos. , vol.34 , pp. 647-652
    • Joshi, M.1    Tyndale, R.F.2
  • 23
    • 0034828240 scopus 로고    scopus 로고
    • Effect of beta-carotene on hepatic cytochrome P-450 in ethanol-fed rats
    • Kessova I.G., Leo M.A., and Lieber C.S. Effect of beta-carotene on hepatic cytochrome P-450 in ethanol-fed rats. Alcohol Clin. Exp. Res. 25 (2001) 1368-1372
    • (2001) Alcohol Clin. Exp. Res. , vol.25 , pp. 1368-1372
    • Kessova, I.G.1    Leo, M.A.2    Lieber, C.S.3
  • 24
    • 0024990750 scopus 로고
    • Differentiated induction of cytochrome P450b/e and P450p mRNAs by dose of phenobarbital in primary cultures of adult rat hepatocytes
    • Kocarek T.A., Schuetz E.G., and Guzelian P.S. Differentiated induction of cytochrome P450b/e and P450p mRNAs by dose of phenobarbital in primary cultures of adult rat hepatocytes. Mol. Pharmacol. 38 (1990) 440-444
    • (1990) Mol. Pharmacol. , vol.38 , pp. 440-444
    • Kocarek, T.A.1    Schuetz, E.G.2    Guzelian, P.S.3
  • 27
    • 0034092716 scopus 로고    scopus 로고
    • CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
    • Leclercq I.A., Farrell G.C., Field J., Bell D.R., Gonzalez F.J., and Robertson G.R. CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis. J. Clin. Invest. 105 (2000) 1067-1075
    • (2000) J. Clin. Invest. , vol.105 , pp. 1067-1075
    • Leclercq, I.A.1    Farrell, G.C.2    Field, J.3    Bell, D.R.4    Gonzalez, F.J.5    Robertson, G.R.6
  • 28
    • 32144443980 scopus 로고    scopus 로고
    • CYP2B6 is expressed in African Green monkey brain and is induced by chronic nicotine treatment
    • Lee A.M., Miksys S., Palmour R., and Tyndale R.F. CYP2B6 is expressed in African Green monkey brain and is induced by chronic nicotine treatment. Neuropharmacology 50 (2006) 441-450
    • (2006) Neuropharmacology , vol.50 , pp. 441-450
    • Lee, A.M.1    Miksys, S.2    Palmour, R.3    Tyndale, R.F.4
  • 29
    • 0028029554 scopus 로고
    • Mechanisms of ethanol-drug-nutrition interactions
    • Lieber C.S. Mechanisms of ethanol-drug-nutrition interactions. J. Toxicol., Clin. Toxicol. 32 (1994) 631-681
    • (1994) J. Toxicol., Clin. Toxicol. , vol.32 , pp. 631-681
    • Lieber, C.S.1
  • 30
    • 0030935567 scopus 로고    scopus 로고
    • Cytochrome P-4502E1: its physiological and pathological role
    • Lieber C.S. Cytochrome P-4502E1: its physiological and pathological role. Physiol. Rev. 77 (1997) 517-544
    • (1997) Physiol. Rev. , vol.77 , pp. 517-544
    • Lieber, C.S.1
  • 31
    • 0033053587 scopus 로고    scopus 로고
    • Microsomal ethanol-oxidizing system (MEOS): the first 30 years (1968-1998)-a review
    • Lieber C.S. Microsomal ethanol-oxidizing system (MEOS): the first 30 years (1968-1998)-a review. Alcohol Clin. Exp. Res. 23 (1999) 991-1007
    • (1999) Alcohol Clin. Exp. Res. , vol.23 , pp. 991-1007
    • Lieber, C.S.1
  • 32
    • 54049130764 scopus 로고    scopus 로고
    • Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment
    • Mann A., Miksys S., Lee A., Mash D.C., and Tyndale R.F. Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment. Neuropharmacology 55 (2008) 1147-1155
    • (2008) Neuropharmacology , vol.55 , pp. 1147-1155
    • Mann, A.1    Miksys, S.2    Lee, A.3    Mash, D.C.4    Tyndale, R.F.5
  • 33
    • 0029990040 scopus 로고    scopus 로고
    • Evidence that cytochrome P-4502E1 contributes to ethanol elimination at low doses: effects of diallyl sulfide and 4-methyl pyrazole on ethanol elimination in the perfused rat liver
    • Matsumoto H., Matsubayashi K., and Fukui Y. Evidence that cytochrome P-4502E1 contributes to ethanol elimination at low doses: effects of diallyl sulfide and 4-methyl pyrazole on ethanol elimination in the perfused rat liver. Alcohol Clin. Exp. Res. 20 (1996) 12A-16A
    • (1996) Alcohol Clin. Exp. Res. , vol.20
    • Matsumoto, H.1    Matsubayashi, K.2    Fukui, Y.3
  • 35
    • 0041430939 scopus 로고    scopus 로고
    • Rat hepatic CYP2E1 is induced by very low nicotine doses: an investigation of induction, time course, dose response, and mechanism
    • Micu A.L., Miksys S., Sellers E.M., Koop D.R., and Tyndale R.F. Rat hepatic CYP2E1 is induced by very low nicotine doses: an investigation of induction, time course, dose response, and mechanism. J. Pharmacol. Exp. Ther. 306 (2003) 941-947
    • (2003) J. Pharmacol. Exp. Ther. , vol.306 , pp. 941-947
    • Micu, A.L.1    Miksys, S.2    Sellers, E.M.3    Koop, D.R.4    Tyndale, R.F.5
  • 36
    • 0034017040 scopus 로고    scopus 로고
    • Regional and cellular induction of nicotine-metabolizing CYP2B1 in rat brain by chronic nicotine treatment
    • Miksys S., Hoffmann E., and Tyndale R.F. Regional and cellular induction of nicotine-metabolizing CYP2B1 in rat brain by chronic nicotine treatment. Biochem. Pharmacol. 59 (2000) 1501-1511
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 1501-1511
    • Miksys, S.1    Hoffmann, E.2    Tyndale, R.F.3
  • 37
    • 0033947897 scopus 로고    scopus 로고
    • Regional and cellular distribution of CYP2D subfamily members in rat brain
    • Miksys S., Rao Y., Sellers E.M., Kwan M., Mendis D., and Tyndale R.F. Regional and cellular distribution of CYP2D subfamily members in rat brain. Xenobiotica 30 (2000) 547-564
    • (2000) Xenobiotica , vol.30 , pp. 547-564
    • Miksys, S.1    Rao, Y.2    Sellers, E.M.3    Kwan, M.4    Mendis, D.5    Tyndale, R.F.6
  • 39
    • 0027304762 scopus 로고
    • Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics
    • Patten C.J., Thomas P.E., Guy R.L., Lee M., Gonzalez F.J., Guengerich F.P., and Yang C.S. Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics. Chem. Res. Toxicol. 6 (1993) 511-518
    • (1993) Chem. Res. Toxicol. , vol.6 , pp. 511-518
    • Patten, C.J.1    Thomas, P.E.2    Guy, R.L.3    Lee, M.4    Gonzalez, F.J.5    Guengerich, F.P.6    Yang, C.S.7
  • 41
    • 0035201366 scopus 로고    scopus 로고
    • Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: studies with cDNA and oligonucleotide expression arrays
    • Rae J.M., Johnson M.D., Lippman M.E., and Flockhart D.A. Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: studies with cDNA and oligonucleotide expression arrays. J. Pharmacol. Exp. Ther. 299 (2001) 849-857
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , pp. 849-857
    • Rae, J.M.1    Johnson, M.D.2    Lippman, M.E.3    Flockhart, D.A.4
  • 42
    • 0029618909 scopus 로고
    • Ethanol induces CYP2E1 by protein stabilization. Role of ubiquitin conjugation in the rapid degradation of CYP2E1
    • Roberts B.J., Song B.J., Soh Y., Park S.S., and Shoaf S.E. Ethanol induces CYP2E1 by protein stabilization. Role of ubiquitin conjugation in the rapid degradation of CYP2E1. J. Biol. Chem. 270 (1995) 29632-29635
    • (1995) J. Biol. Chem. , vol.270 , pp. 29632-29635
    • Roberts, B.J.1    Song, B.J.2    Soh, Y.3    Park, S.S.4    Shoaf, S.E.5
  • 44
    • 0022499774 scopus 로고
    • Evidence that isoniazid and ethanol induce the same microsomal cytochrome P-450 in rat liver, an isozyme homologous to rabbit liver cytochrome P-450 isozyme 3a
    • Ryan D.E., Koop D.R., Thomas P.E., Coon M.J., and Levin W. Evidence that isoniazid and ethanol induce the same microsomal cytochrome P-450 in rat liver, an isozyme homologous to rabbit liver cytochrome P-450 isozyme 3a. Arch. Biochem. Biophys. 246 (1986) 633-644
    • (1986) Arch. Biochem. Biophys. , vol.246 , pp. 633-644
    • Ryan, D.E.1    Koop, D.R.2    Thomas, P.E.3    Coon, M.J.4    Levin, W.5
  • 45
    • 0037450449 scopus 로고    scopus 로고
    • Induction of nicotine-metabolizing CYP2B1 by ethanol and ethanol-metabolizing CYP2E1 by nicotine: summary and implications
    • Schoedel K.A., and Tyndale R.F. Induction of nicotine-metabolizing CYP2B1 by ethanol and ethanol-metabolizing CYP2E1 by nicotine: summary and implications. Biochim. Biophys. Acta. 1619 (2003) 283-290
    • (2003) Biochim. Biophys. Acta. , vol.1619 , pp. 283-290
    • Schoedel, K.A.1    Tyndale, R.F.2
  • 46
    • 0035501355 scopus 로고    scopus 로고
    • Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain
    • Schoedel K.A., Sellers E.M., and Tyndale R.F. Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain. Biochem. Pharmacol. 62 (2001) 1025-1036
    • (2001) Biochem. Pharmacol. , vol.62 , pp. 1025-1036
    • Schoedel, K.A.1    Sellers, E.M.2    Tyndale, R.F.3
  • 49
    • 0024521525 scopus 로고
    • Induction of rat hepatic N-nitrosodimethylamine demethylase by acetone is due to protein stabilization
    • Song B.J., Veech R.L., Park S.S., Gelboin H.V., and Gonzalez F.J. Induction of rat hepatic N-nitrosodimethylamine demethylase by acetone is due to protein stabilization. J. Biol. Chem. 264 (1989) 3568-3572
    • (1989) J. Biol. Chem. , vol.264 , pp. 3568-3572
    • Song, B.J.1    Veech, R.L.2    Park, S.S.3    Gelboin, H.V.4    Gonzalez, F.J.5
  • 51
    • 0025116753 scopus 로고
    • Behavioural pharmacology of nicotine: implications for multiple brain nicotinic receptors
    • discussion 16-22
    • Stolerman I.P. Behavioural pharmacology of nicotine: implications for multiple brain nicotinic receptors. Ciba Found. Symp. 152 (1990) 3-16 discussion 16-22
    • (1990) Ciba Found. Symp. , vol.152 , pp. 3-16
    • Stolerman, I.P.1
  • 52
    • 0028968934 scopus 로고
    • Dissociations between the locomotor stimulant and depressant effects of nicotinic agonists in rats
    • Stolerman I.P., Garcha H.S., and Mirza N.R. Dissociations between the locomotor stimulant and depressant effects of nicotinic agonists in rats. Psychopharmacology (Berl). 117 (1995) 430-437
    • (1995) Psychopharmacology (Berl). , vol.117 , pp. 430-437
    • Stolerman, I.P.1    Garcha, H.S.2    Mirza, N.R.3
  • 53
    • 0032478735 scopus 로고    scopus 로고
    • The CYP2B2 phenobarbital response unit contains an accessory factor element and a putative glucocorticoid response element essential for conferring maximal phenobarbital responsiveness
    • Stoltz C., Vachon M.H., Trottier E., Dubois S., Paquet Y., and Anderson A. The CYP2B2 phenobarbital response unit contains an accessory factor element and a putative glucocorticoid response element essential for conferring maximal phenobarbital responsiveness. J. Biol. Chem. 273 (1998) 8528-8536
    • (1998) J. Biol. Chem. , vol.273 , pp. 8528-8536
    • Stoltz, C.1    Vachon, M.H.2    Trottier, E.3    Dubois, S.4    Paquet, Y.5    Anderson, A.6
  • 54
    • 3843081919 scopus 로고    scopus 로고
    • The effect of baclofen alone and in combination with naltrexone on ethanol consumption in the rat
    • Stromberg M.F. The effect of baclofen alone and in combination with naltrexone on ethanol consumption in the rat. Pharmacol. Biochem. Behav. 78 (2004) 743-750
    • (2004) Pharmacol. Biochem. Behav. , vol.78 , pp. 743-750
    • Stromberg, M.F.1
  • 55
    • 0031949311 scopus 로고    scopus 로고
    • A comparison of the effects of the opioid antagonists naltrexone, naltrindole, and beta-funaltrexamine on ethanol consumption in the rat
    • Stromberg M.F., Casale M., Volpicelli L., Volpicelli J.R., and O'Brien C.P. A comparison of the effects of the opioid antagonists naltrexone, naltrindole, and beta-funaltrexamine on ethanol consumption in the rat. Alcohol 15 (1998) 281-289
    • (1998) Alcohol , vol.15 , pp. 281-289
    • Stromberg, M.F.1    Casale, M.2    Volpicelli, L.3    Volpicelli, J.R.4    O'Brien, C.P.5
  • 56
    • 0028035492 scopus 로고
    • Genotoxicity of tamoxifen, tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s
    • Styles J.A., Davies A., Lim C.K., De Matteis F., Stanley L.A., White I.N., Yuan Z.X., and Smith L.L. Genotoxicity of tamoxifen, tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s. Carcinogenesis 15 (1994) 5-9
    • (1994) Carcinogenesis , vol.15 , pp. 5-9
    • Styles, J.A.1    Davies, A.2    Lim, C.K.3    De Matteis, F.4    Stanley, L.A.5    White, I.N.6    Yuan, Z.X.7    Smith, L.L.8
  • 57
    • 0031057732 scopus 로고    scopus 로고
    • Heavy consumption of cigarettes, alcohol and coffee in male twins
    • Swan G.E., Carmelli D., and Cardon L.R. Heavy consumption of cigarettes, alcohol and coffee in male twins. J. Stud. Alcohol 58 (1997) 182-190
    • (1997) J. Stud. Alcohol , vol.58 , pp. 182-190
    • Swan, G.E.1    Carmelli, D.2    Cardon, L.R.3
  • 59
    • 0037764979 scopus 로고    scopus 로고
    • Genetics of alcohol and tobacco use in humans
    • Tyndale R.F. Genetics of alcohol and tobacco use in humans. Ann. Med. 35 (2003) 94-121
    • (2003) Ann. Med. , vol.35 , pp. 94-121
    • Tyndale, R.F.1
  • 60
    • 0025073482 scopus 로고
    • Transcriptional control of the rat hepatic CYP2E1 gene
    • Ueno T., and Gonzalez F.J. Transcriptional control of the rat hepatic CYP2E1 gene. Mol. Cell. Biol. 10 (1990) 4495-4505
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 4495-4505
    • Ueno, T.1    Gonzalez, F.J.2
  • 61
    • 0348038715 scopus 로고    scopus 로고
    • Transcriptional regulation of cytochrome p450 2B genes by nuclear receptors
    • Wang H., and Negishi M. Transcriptional regulation of cytochrome p450 2B genes by nuclear receptors. Curr. Drug. Metab. 4 (2003) 515-525
    • (2003) Curr. Drug. Metab. , vol.4 , pp. 515-525
    • Wang, H.1    Negishi, M.2
  • 62
    • 52449133102 scopus 로고    scopus 로고
    • CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme
    • Wang H., and Tompkins L.M. CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme. Curr. Drug. Metab. 9 (2008) 598-610
    • (2008) Curr. Drug. Metab. , vol.9 , pp. 598-610
    • Wang, H.1    Tompkins, L.M.2
  • 63
    • 0038002981 scopus 로고    scopus 로고
    • The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity
    • Ward B.A., Gorski J.C., Jones D.R., Hall S.D., Flockhart D.A., and Desta Z. The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity. J. Pharmacol. Exp. Ther. 306 (2003) 287-300
    • (2003) J. Pharmacol. Exp. Ther. , vol.306 , pp. 287-300
    • Ward, B.A.1    Gorski, J.C.2    Jones, D.R.3    Hall, S.D.4    Flockhart, D.A.5    Desta, Z.6
  • 66
    • 0030719427 scopus 로고    scopus 로고
    • Insulin effects on CYP2E1, 2B, 3A, and 4A expression in primary cultured rat hepatocytes
    • Woodcroft K.J., and Novak R.F. Insulin effects on CYP2E1, 2B, 3A, and 4A expression in primary cultured rat hepatocytes. Chem. Biol. Interact. 107 (1997) 75-91
    • (1997) Chem. Biol. Interact. , vol.107 , pp. 75-91
    • Woodcroft, K.J.1    Novak, R.F.2
  • 67
    • 0031943842 scopus 로고    scopus 로고
    • Xenobiotic-enhanced expression of cytochromes P450 2E1 and 2B in primary cultured rat hepatocytes
    • Woodcroft K.J., and Novak R.F. Xenobiotic-enhanced expression of cytochromes P450 2E1 and 2B in primary cultured rat hepatocytes. Drug. Metab. Dispos. 26 (1998) 372-378
    • (1998) Drug. Metab. Dispos. , vol.26 , pp. 372-378
    • Woodcroft, K.J.1    Novak, R.F.2
  • 68
    • 39149094615 scopus 로고    scopus 로고
    • Chronic nicotine treatment induces rat CYP2D in the brain but not in the liver: an investigation of induction and time course
    • Yue J., Miksys S., Hoffmann E., and Tyndale R.F. Chronic nicotine treatment induces rat CYP2D in the brain but not in the liver: an investigation of induction and time course. J. Psychiatry Neurosci. 33 (2008) 54-63
    • (2008) J. Psychiatry Neurosci. , vol.33 , pp. 54-63
    • Yue, J.1    Miksys, S.2    Hoffmann, E.3    Tyndale, R.F.4
  • 69
    • 0033151930 scopus 로고    scopus 로고
    • Relationship between cytochrome P450 catalytic cycling and stability: fast degradation of ethanol-inducible cytochrome P450 2E1 (CYP2E1) in hepatoma cells is abolished by inactivation of its electron donor NADPH-cytochrome P450 reductase
    • Zhukov A., and Ingelman-Sundberg M. Relationship between cytochrome P450 catalytic cycling and stability: fast degradation of ethanol-inducible cytochrome P450 2E1 (CYP2E1) in hepatoma cells is abolished by inactivation of its electron donor NADPH-cytochrome P450 reductase. Biochem. J. 340 (1999) 453-458
    • (1999) Biochem. J. , vol.340 , pp. 453-458
    • Zhukov, A.1    Ingelman-Sundberg, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.