CS5931, a novel polypeptide in Ciona savignyi, represses angiogenesis via inhibiting vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs)

Marine Drugs

Volumn 12, Issue 3, 2014, Pages 1530-1544

  Liu, Ge ^a,b   Liu, Ming ^c   Wei, Jianteng ^d   Huang, Haijuan ^e   Zhang, Yuyan ^e   Zhao, Jin ^f   Xiao, Lin ^g   Wu, Ning ^a   Zheng, Lanhong ^h   Lin, Xiukun ⁱ  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c OCEAN UNIVERSITY OF CHINA   (China)

^d LANZHOU INSTITUTE OF CHEMICAL PHYSICS   (China)

^e QINGDAO UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^f ZHENGZHOU UNIVERSITY   (China)

^g QINGDAO AGRICULTURAL UNIVERSITY   (China)

^h YELLOW SEA FISHERIES RESEARCH INSTITUTE   (China)

ⁱ CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Anti angiogenesis; CS5931; HUVECs; VEGF and MMPs; Zebrafish

Indexed keywords

ANGIOGENESIS INHIBITOR; CS 5931; GELATINASE A; GELATINASE B; MESSENGER RNA; POLYPEPTIDE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; BLOOD VESSEL; CELL MIGRATION; CELL PROLIFERATION; CIONA SAVIGNYI; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL VEIN ENDOTHELIAL CELL; UROCHORDATA; WESTERN BLOTTING; ZEBRA FISH;

ALKALINE PHOSPHATASE; ANGIOGENESIS INHIBITORS; ANIMALS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; COLORING AGENTS; EMBRYO, NONMAMMALIAN; FEMALE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MATRIX METALLOPROTEINASE INHIBITORS; MATRIX METALLOPROTEINASES; PREGNANCY; REAL-TIME POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; RNA, MESSENGER; TETRAZOLIUM SALTS; THIAZOLES; UMBILICAL CORD; UROCHORDATA; VASCULAR ENDOTHELIAL GROWTH FACTOR A; ZEBRAFISH;

EID: 84897102387     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md12031530     Document Type: Article

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