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Volumn 90, Issue 12, 2004, Pages 2418-2424

Antiangiogenic activity of aplidine, a new agent of marine origin

Author keywords

Angiogenesis inhibition; Aplidine; Didemnin; Endothelial cells

Indexed keywords

DEHYDRODIDEMNIN B; FIBROBLAST GROWTH FACTOR 2; GELATINASE A; GELATINASE B; MATRIGEL; VASCULOTROPIN; ANGIOGENESIS INHIBITOR; CYCLOPEPTIDE; DEPSIPEPTIDE; MATRIX METALLOPROTEINASE;

EID: 3042743711     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6601864     Document Type: Article
Times cited : (88)

References (40)
  • 1
    • 0036288919 scopus 로고    scopus 로고
    • In vitro toxicity of ET-743 and aplidine, two marine-derived antineoplastics, on human bone marrow haematopoietic progenitors. Comparison with the clinical results
    • Albella B, Faircloth G, Lopez-Lazaro L, Guzman C, Jimeno J, Eueren JA (2002) In vitro toxicity of ET-743 and aplidine, two marine-derived antineoplastics, on human bone marrow haematopoietic progenitors. Comparison with the clinical results. Eur J Cancer 38: 1395-1404
    • (2002) Eur J Cancer , vol.38 , pp. 1395-1404
    • Albella, B.1    Faircloth, G.2    Lopez-Lazaro, L.3    Guzman, C.4    Jimeno, J.5    Eueren, J.A.6
  • 4
    • 0037265805 scopus 로고    scopus 로고
    • Aplidine, a new anticancer agent of marine origin, inhibits vascular endothelial growth factor (VEGF) secretion and blocks VEGF-VEGFR-1 (flt-1) autocrine loop in human leukemia cells MOLT-4
    • Broggini M, Marchini SV, Galliera E, Borsotti P, Taraboletti G, Erba E, Sironi M, Jimeno J, Faircloth GT, Giavazzi R, D'Incalci M (2003) Aplidine, a new anticancer agent of marine origin, inhibits vascular endothelial growth factor (VEGF) secretion and blocks VEGF-VEGFR-1 (flt-1) autocrine loop in human leukemia cells MOLT-4. Leukemia 17: 52-59
    • (2003) Leukemia , vol.17 , pp. 52-59
    • Broggini, M.1    Marchini, S.V.2    Galliera, E.3    Borsotti, P.4    Taraboletti, G.5    Erba, E.6    Sironi, M.7    Jimeno, J.8    Faircloth, G.T.9    Giavazzi, R.10    D'Incalci, M.11
  • 5
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK (2000) Angiogenesis in cancer and other diseases. Nature 407: 249-257
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 6
    • 0028300782 scopus 로고
    • GTP-dependent binding of the antiproliferative agent didemnin to elongation factor 1 alpha
    • Crews CM, Collins JL, Lane WS, Snapper ML, Schreiber SL (1994) GTP-dependent binding of the antiproliferative agent didemnin to elongation factor 1 alpha. J Biol Chem 269: 15411-15414
    • (1994) J Biol Chem , vol.269 , pp. 15411-15414
    • Crews, C.M.1    Collins, J.L.2    Lane, W.S.3    Snapper, M.L.4    Schreiber, S.L.5
  • 7
    • 0029913829 scopus 로고    scopus 로고
    • Didemnin binds to the protein palmitoyl thioesterase responsible for infantile neuronal ceroid lipofuscinosis
    • Crews CM, Lane WS, Schreiber SL (1996) Didemnin binds to the protein palmitoyl thioesterase responsible for infantile neuronal ceroid lipofuscinosis. Proc Natl Acad Sci USA 93: 4316-4319
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 4316-4319
    • Crews, C.M.1    Lane, W.S.2    Schreiber, S.L.3
  • 10
    • 0031713769 scopus 로고    scopus 로고
    • In vitro activity of aplidine, a new marine-derived anti-cancer compound, on freshly explanted clonogenic human tumour cells and haematopoietic precursor cells
    • Depenbrock H, Peter R, Faircloth GT, Manzanares I, Jimeno J, Hanauske AR (1998) In vitro activity of aplidine, a new marine-derived anti-cancer compound, on freshly explanted clonogenic human tumour cells and haematopoietic precursor cells. Br J Cancer 78: 739-744
    • (1998) Br J Cancer , vol.78 , pp. 739-744
    • Depenbrock, H.1    Peter, R.2    Faircloth, G.T.3    Manzanares, I.4    Jimeno, J.5    Hanauske, A.R.6
  • 13
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman J (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1: 27-31
    • (1995) Nat Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 14
    • 0034194582 scopus 로고    scopus 로고
    • Human myeloid and lymphoid malignancies in the non-obese diabetic/severe combined immunodeficiency mouse model: Frequency of apoptotic cells in solid tumors and efficiency and speed of engraftment correlate with vascular endothelial growth factor production
    • Fusetti L, Pruneri G, Gobbi A, Rabascio C, Carboni N, Peccatori F, Martinelli G, Bertolini F (2000) Human myeloid and lymphoid malignancies in the non-obese diabetic/severe combined immunodeficiency mouse model: frequency of apoptotic cells in solid tumors and efficiency and speed of engraftment correlate with vascular endothelial growth factor production. Cancer Res 60: 2527-2534
    • (2000) Cancer Res , vol.60 , pp. 2527-2534
    • Fusetti, L.1    Pruneri, G.2    Gobbi, A.3    Rabascio, C.4    Carboni, N.5    Peccatori, F.6    Martinelli, G.7    Bertolini, F.8
  • 15
    • 0037388458 scopus 로고    scopus 로고
    • Rapid and selective apoptosis in human leukemic cells induced by aplidine through a Fas/CD95- and mitochondrial-mediated mechanism
    • Gajate C, An F, Mollinedo F (2003) Rapid and selective apoptosis in human leukemic cells induced by aplidine through a Fas/CD95- and mitochondrial- mediated mechanism. Clin Cancer Res 9: 1535-1545
    • (2003) Clin Cancer Res , vol.9 , pp. 1535-1545
    • Gajate, C.1    An, F.2    Mollinedo, F.3
  • 16
    • 0032780130 scopus 로고    scopus 로고
    • Cytotoxicity and neurocytotoxicity of new marine anticancer agents evaluated using in vitro assays
    • Geldof AA, Mastbergen SC, Henrar RE, Faircloth GT (1999) Cytotoxicity and neurocytotoxicity of new marine anticancer agents evaluated using in vitro assays. Cancer Chemother Pharmacol 44: 312-318
    • (1999) Cancer Chemother Pharmacol , vol.44 , pp. 312-318
    • Geldof, A.A.1    Mastbergen, S.C.2    Henrar, R.E.3    Faircloth, G.T.4
  • 18
    • 0031586761 scopus 로고    scopus 로고
    • Polyamine contents of human breast cancer cells treated with the cytotoxic agents chlorpheniramine and dehydrodidemnin B
    • Gomez-Fabre PM, de Pedro E, Medina MA, Nunez de Castro I, Marquez J (1997) Polyamine contents of human breast cancer cells treated with the cytotoxic agents chlorpheniramine and dehydrodidemnin B. Cancer Lett 113: 141-144
    • (1997) Cancer Lett , vol.113 , pp. 141-144
    • Gomez-Fabre, P.M.1    De Pedro, E.2    Medina, M.A.3    Nunez De Castro, I.4    Marquez, J.5
  • 20
    • 0034048358 scopus 로고    scopus 로고
    • Less is more, regularly: Metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice
    • Hanahan D, Bergers G, Bergsland E (2000) Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice. J Clin Invest 105: 1045-1047
    • (2000) J Clin Invest , vol.105 , pp. 1045-1047
    • Hanahan, D.1    Bergers, G.2    Bergsland, E.3
  • 21
    • 0036273081 scopus 로고    scopus 로고
    • A clinical armamentarium of marine-derived anti-cancer compounds
    • Jimeno JM (2002) A clinical armamentarium of marine-derived anti-cancer compounds. Anticancer Drugs 13: S15-S19
    • (2002) Anticancer Drugs , vol.13
    • Jimeno, J.M.1
  • 22
    • 0036780251 scopus 로고    scopus 로고
    • Clinical translation of angiogenesis inhibitors
    • Kerbel R, Folkman J (2002) Clinical translation of angiogenesis inhibitors. Nat Rev Cancer 2: 727-739
    • (2002) Nat Rev Cancer , vol.2 , pp. 727-739
    • Kerbel, R.1    Folkman, J.2
  • 23
    • 0034087691 scopus 로고    scopus 로고
    • Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity
    • Klement G, Baruchel S, Rak J, Man S, Clark K, Hicklin DJ, Bohlen P, Kerbel RS (2000) Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity. J Clin Invest 105: R15-R24
    • (2000) J Clin Invest , vol.105
    • Klement, G.1    Baruchel, S.2    Rak, J.3    Man, S.4    Clark, K.5    Hicklin, D.J.6    Bohlen, P.7    Kerbel, R.S.8
  • 24
    • 0017341618 scopus 로고
    • Avascular and vascular phases of tumour growth in the chick embryo
    • Knighton D, Ausprunk D, Tapper D, Folkman J (1977) Avascular and vascular phases of tumour growth in the chick embryo. Br J Cancer 35: 347-356
    • (1977) Br J Cancer , vol.35 , pp. 347-356
    • Knighton, D.1    Ausprunk, D.2    Tapper, D.3    Folkman, J.4
  • 26
    • 1842852886 scopus 로고    scopus 로고
    • Changes in gene expression profile induced by the anticancer agent Aplidine in Molt-4 leukemic cell lines
    • Marchini S, Chiorino G, Faircloth GT, D'Incalci M (2002) Changes in gene expression profile induced by the anticancer agent Aplidine in Molt-4 leukemic cell lines. J Biol Regul Homeost Agents 16: 241-248
    • (2002) J Biol Regul Homeost Agents , vol.16 , pp. 241-248
    • Marchini, S.1    Chiorino, G.2    Faircloth, G.T.3    D'Incalci, M.4
  • 27
    • 0035865363 scopus 로고    scopus 로고
    • Redefining the target: Chemotherapeutics as antiangiogenics
    • Miller KD, Sweeney CJ, Sledge Jr GW (2001) Redefining the target: chemotherapeutics as antiangiogenics. J Clin Oncol 19: 1195-1206
    • (2001) J Clin Oncol , vol.19 , pp. 1195-1206
    • Miller, K.D.1    Sweeney, C.J.2    Sledge Jr., G.W.3
  • 28
    • 0036235016 scopus 로고    scopus 로고
    • Protein overload-induced NF-kappaB activation in proximal tubular cells requires H(2)O(2) through a PKC-dependent pathway
    • Morigi M, Macconi D, Zoja C, Donadelli R, Buelli S, Zanchi C, Ghilardi M, Remuzzi G (2002) Protein overload-induced NF-kappaB activation in proximal tubular cells requires H(2)O(2) through a PKC-dependent pathway. J Am Soc Nephrol 13: 1179-1189
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1179-1189
    • Morigi, M.1    Macconi, D.2    Zoja, C.3    Donadelli, R.4    Buelli, S.5    Zanchi, C.6    Ghilardi, M.7    Remuzzi, G.8
  • 29
    • 0033984493 scopus 로고    scopus 로고
    • The relationship between angiogenesis and the immune response in carcinogenesis and the progression of malignant disease
    • O'Byrne KJ, Dalgleish AG, Browning MJ, Steward WP, Harris AL (2000) The relationship between angiogenesis and the immune response in carcinogenesis and the progression of malignant disease. Eur J Cancer 36: 151-169
    • (2000) Eur J Cancer , vol.36 , pp. 151-169
    • O'Byrne, K.J.1    Dalgleish, A.G.2    Browning, M.J.3    Steward, W.P.4    Harris, A.L.5
  • 30
    • 0036855805 scopus 로고    scopus 로고
    • Thalidomide and immunomodulatory drugs as cancer therapy
    • Raje N, Anderson KC (2002) Thalidomide and immunomodulatory drugs as cancer therapy. Curr Opin Oncol 14: 635-640
    • (2002) Curr Opin Oncol , vol.14 , pp. 635-640
    • Raje, N.1    Anderson, K.C.2
  • 31
    • 0031469270 scopus 로고    scopus 로고
    • New model for the study of angiogenesis and antiangiogenesis in the chick embryo chorioallantoic membrane: The gelatin sponge/chorioallantoic membrane assay
    • Ribatti D, Gualandris A, Bastaki M, Vacca A, Iurlaro M, Roncali L, Presta M (1997) New model for the study of angiogenesis and antiangiogenesis in the chick embryo chorioallantoic membrane: the gelatin sponge/chorioallantoic membrane assay. J Vasc Res 34: 455-463
    • (1997) J Vasc Res , vol.34 , pp. 455-463
    • Ribatti, D.1    Gualandris, A.2    Bastaki, M.3    Vacca, A.4    Iurlaro, M.5    Roncali, L.6    Presta, M.7
  • 32
    • 0035576088 scopus 로고    scopus 로고
    • Chorioallantoic membrane capillary bed: A useful target for studying angiogenesis and anti-angiogenesis in vivo
    • Ribatti D, Nico B, Vacca A, Roncali L, Burri PH, Djonov V (2001) Chorioallantoic membrane capillary bed: a useful target for studying angiogenesis and anti-angiogenesis in vivo. Anat Rec 264: 317-324
    • (2001) Anat Rec , vol.264 , pp. 317-324
    • Ribatti, D.1    Nico, B.2    Vacca, A.3    Roncali, L.4    Burri, P.H.5    Djonov, V.6
  • 34
    • 0034534249 scopus 로고    scopus 로고
    • Antiangiogenic chemotherapeutic agents
    • Schirner M (2000) Antiangiogenic chemotherapeutic agents. Cancer Metast Rev 19: 67-73
    • (2000) Cancer Metast Rev , vol.19 , pp. 67-73
    • Schirner, M.1
  • 38
    • 0031661585 scopus 로고    scopus 로고
    • Synthetic analogues of TNP-470 and ovalicin reveal a common molecular basis for inhibition of angiogenesis and immunosuppression
    • Turk BE, Su Z, Liu JO (1998) Synthetic analogues of TNP-470 and ovalicin reveal a common molecular basis for inhibition of angiogenesis and immunosuppression. Bioorg Med Chem 6: 1163-1169
    • (1998) Bioorg Med Chem , vol.6 , pp. 1163-1169
    • Turk, B.E.1    Su, Z.2    Liu, J.O.3
  • 39
    • 0029670281 scopus 로고    scopus 로고
    • Antiproliferative effect of dehydrodidemnin B (DDB), a depsipeptide isolated from Mediterranean tunicates
    • Urdiales JL, Morata P, Nunez De Castro I, Sanchez-Jimenez F (1996) Antiproliferative effect of dehydrodidemnin B (DDB), a depsipeptide isolated from Mediterranean tunicates. Cancer Lett 102: 31-37
    • (1996) Cancer Lett , vol.102 , pp. 31-37
    • Urdiales, J.L.1    Morata, P.2    Nunez De Castro, I.3    Sanchez-Jimenez, F.4
  • 40
    • 0036178591 scopus 로고    scopus 로고
    • Natural products as probes of cell biology: 20 Years of didemnin research
    • Vera MD, Joullie MM (2002) Natural products as probes of cell biology: 20 years of didemnin research. Med Res Rev 22: 102-145
    • (2002) Med Res Rev , vol.22 , pp. 102-145
    • Vera, M.D.1    Joullie, M.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.