Anti-angiogenic effects of rhubarb and its anthraquinone derivatives

Journal of Ethnopharmacology

Volumn 121, Issue 2, 2009, Pages 313-317

  He, Zhi Heng ^a   He, Ming Fang ^a   Ma, Shuang Cheng ^b   But, Paul Pui Hay ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b NATIONAL INSTITUTE FOR THE CONTROL OF PHARMACEUTICAL AND BIOLOGICAL PRODUCTS   (China)

Author keywords

Anthraquinone; Anti angiogenesis; Rhein; Rheum; Rhubarb; Zebrafish

Indexed keywords

ALKALINE PHOSPHATASE; ALOE EMODIN; ANTHRAQUINONE DERIVATIVE; EMODIN; PHYSCION; RHEIN; RHUBARB EXTRACT;

ACIDITY; ANTIANGIOGENIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; EMBRYO; ENZYME ASSAY; HYDROPHILICITY; NONHUMAN; PLANT ROOT; QUANTITATIVE ANALYSIS; ZEBRA FISH;

ALKALINE PHOSPHATASE; ANGIOGENESIS INHIBITORS; ANIMALS; ANTHRAQUINONES; DISEASE MODELS, ANIMAL; MEDICINE, CHINESE TRADITIONAL; NEOVASCULARIZATION, PATHOLOGIC; PLANT EXTRACTS; PLANT ROOTS; RHEUM; STRUCTURE-ACTIVITY RELATIONSHIP; ZEBRAFISH;

ALOE; DANIO RERIO; RHEUM; RHEUM X HYBRIDUM;

EID: 57949102533     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2008.11.008     Document Type: Article

References (38)

1. Albini A., Tosetti F., Benelli R., and Noonan D.M. Tumor inflammatory angiogenesis and its chemoprevention. Cancer Research 65 (2005) 10637-10641
2. Allavena P., Garlanda C., Borrello M.G., Sica A., and Mantovani A. Pathways connecting inflammation and cancer. Current Opinion in Genetics & Development 18 (2008) 3-10
3. Anon. Zhongguo Fangjixue (Chinese Formulary) (1976), Chinese Herb Research and Development Press, Taipei p. 289
4. Bisacchi D., Benelli R., Vanzetto C., Ferrari N., Tosetti F., and Albini A. Anti-angiogenesis and angioprevention: mechanisms, problems and perspectives. Cancer Detection and Prevention 27 (2003) 229-238
5. Cardenas C., Quesada A.R., and Medina M.A. Evaluation of the anti-angiogenic effect of aloe-emodin. Cellular and Molecular Life Sciences 63 (2006) 3083-3089
6. Chan J., Bayliss P.E., Wood J.M., and Roberts T.M. Dissection of angiogenic signaling in zebrafish using a chemical genetic approach. Cancer Cell 1 (2002) 257-267
7. Chinese Pharmacopoeia Commission. Pharmacopoeia of the People's Republic of China (2005), Chemical Industry Press, Beijing p. 17
8. Crawford A.D., Esguerra C.V., and de Witte P.A. Fishing for drugs from nature: zebrafish as a technology platform for natural product discovery. Planta Medica 74 (2008) 624-632
9. Cuellar M.J., Giner R.M., Recio M.C., Manez S., and Rios J.L. Topical anti-inflammatory activity of some Asian medicinal plants used in dermatological disorders. Fitoterapia 72 (2001) 221-229
10. Dorsey J.F., and Kao G.D. Aloe(-emodin) for cancer? More than just a comforting salve. Cancer Biology and Therapy 6 (2007) 89-90
11. Folkman J. Tumor angiogenesis: therapeutic implications. The New England Journal of Medicine 285 (1971) 1182-1186
12. Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nature Medicine b 1 (1995) 27-31
13. Fotsis T., Pepper M., Adlercreutz H., Fleischmann G., Hase T., Montesano R., et al. Genistein, a dietary-derived inhibitor of in vitro angiogenesis. Proceedings of the National Academy of Sciences USA 90 (1993) 2690-2694
14. He M.F., Liu L., Ge W., Shaw P.C., Jiang R.W., Wu L.W., and But P.P.H. Antianiogenic activity of Tripterygium wilfordii and its terpenoids. Journal of Ethnopharmacology 121 (2009) 61-68
15. Huang Q., Lu G., Shen H.M., Chung M.C., and Ong C.N. Anti-cancer properties of anthraquinones from rhubarb. Medicinal Research Reviews 27 (2007) 609-630
16. Joensuu H., De Braud F., Coco P., De Pas T., Putzu C., Spreafico C., et al. Phase II, open-label study of PTK787/ZK222584 for the treatment of metastatic gastrointestinal stromal tumors resistant to imatinib mesylate. Annals of Oncology 19 (2008) 173-177
17. Koo H.J., Lee S., Shin K.H., Kim B.C., Lim C.J., and Park E.H. Geniposide, an anti-angiogenic compound from the fruits of Gardenia jasminoides. Planta Medica 70 (2004) 467-469
18. Koo H.J., Song Y.S., Kim H.J., Lee Y.H., Hong S.M., Kim S.J., et al. Antiinflammatory effects of genipin, an active principle of gardenia. European Journal of Pharmacology 495 (2004) 201-208
19. Kwak H.J., Park M.J., Park C.M., Moon S.I., Yoo D.H., Lee H.C., et al. Emodin inhibits vascular endothelial growth factor-A-induced angiogenesis by blocking receptor-2 (KDR/Flk-1) phosphorylation. International Journal of Cancer 118 (2006) 2711-2720
20. Langheinrich U. Zebrafish: a new model on the pharmaceutical catwalk. Bioessays 25 (2003) 904-912
21. Lee E.O., Lee H.J., Hwang H.S., Ahn K.S., Chae C., Kang K.S., et al. Potent inhibition of Lewis lung cancer growth by heyneanol A from the roots of Vitis amurensis through apoptotic and anti-angiogenic activities. Carcinogenesis 27 (2006) 2059-2069
22. Lee H.Z., Hsu S.L., Liu M.C., and Wu C.H. Effects and mechanisms of aloe-emodin on cell death in human lung squamous cell carcinoma. European Journal of Pharmacology 431 (2001) 287-295
23. Ljubimov A.V., Caballero S., Aoki A.M., Pinna L.A., Grant M.B., and Castellon R. Involvement of protein kinase CK2 in angiogenesis and retinal neovascularization. Investigative Ophthalmology & Visual Science 45 (2004) 4583-4591
24. Liu J.J., Huang T.S., Cheng W.F., and Lu F.J. Baicalein and baicalin are potent inhibitors of angiogenesis: Inhibition of endothelial cell proliferation, migration and differentiation. International Journal of Cancer 106 (2003) 559-565
25. Norrby K. In vivo models of angiogenesis. Journal of Cellular and Molecular Medicine 10 (2006) 588-612
26. Parng C., Seng W.L., Semino C., and McGrath P. Zebrafish: a preclinical model or drug screening. Assay and Drug Development Technologies 1 (2002) 41-48
27. Qiu P.R. A Collection of Famous Prescriptions Down the Ages (1994), Shanghai Lexicographical Publishing House, Shanghai pp. 353, 365, 526
28. Sengupta S., Toh S.A., Sellers L.A., Skepper J.N., Koolwijk P., Leung H.W., et al. Modulating angiogenesis: the yin and the yang in ginseng. Circulation 110 (2004) 1219-1225
29. Serbedzija G.N., Flynn E., and Willett C.E. Zebrafish angiogenesis: a new model for drug screening. Angiogenesis 3 (1999) 353-359
30. Shi Y.Q., Fukai T., Sakagami H., Kuroda J., Miyaoka R., Tamura M., et al. Cytotoxic and DNA damage-inducing activities of low molecular weight phenols from rhubarb. Anticancer Research 21 (2001) 2847-2853
31. Stern H.M., and Zon L.I. Cancer genetics and drug discovery in the zebrafish. Nature Reviews Cancer 3 (2003) 533-539
32. Tang W., Hemm I., and Bertram B. Recent development of antitumor agents from chinese herbal medicines. Part I. Low molecular compounds. Planta Medica 69 (2003) 97-108
33. Taraboletti G., and Giavazzi R. Modelling approaches for angiogenesis. European Journal of Cancer 40 (2004) 881-889
34. Wang C.C., Huang Y.J., Chen L.G., Lee L.T., and Yang L.L. Inducible nitric oxide synthase inhibitors of Chinese herbs III Rheum palmatum. Planta Medica 68 (2002) 869-874
35. Wang X.H., Wu S.Y., and Zhen Y.S. Inhibitory effects of emodin on angiogenesis. Yao Xue Xue Bao 39 (2004) 254-258
36. Westerfield M. The Zebrafish Book: A Guide for the Laboratory Use of Zebrafish (1993), University of Oregon Press, Eugene, OR
37. 3 on Lewis lung carcinoma. Biochemical and Biophysical Research Communications 342 (2006) 824-828
38. Zon L.I., and Peterson R.T. In vivo drug discovery in the zebrafish. Nature Reviews Drug Discovery 4 (2005) 35-44