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Volumn 5, Issue , 2014, Pages

Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling

(20)  Chen, Wan Jiun a,b   Ho, Chao Chi c   Chang, Yih Leong a   Chen, Hsuan Yu b   Lin, Chih An a   Ling, Thai Yen a   Yu, Sung Liang a   Yuan, Shin Sheng b   Louisa Chen, Yu Ju b   Lin, Chien Yu b   Pan, Szu Hua a   Elizabeth Chou, Han Yi d,e   Chang, Gee Chen f,g   Chu, Wen Cheng a   Lee, Yee Ming a   Lee, Jen Yi a   Lee, Pei Jung a   Li, Ker Chau b,h   Chen, Huei Wen a,d   Yang, Pan Chyr a,c,i  


Author keywords

[No Author keywords available]

Indexed keywords

OCTAMER TRANSCRIPTION FACTOR 4; ORGANIC CATION TRANSPORTER 3; SOMATOMEDIN B; SOMATOMEDIN RECEPTOR; TRANSCRIPTION FACTOR NANOG; HOMEODOMAIN PROTEIN; IGF1R PROTEIN, HUMAN; NANOG PROTEIN, HUMAN; POU5F1 PROTEIN, HUMAN; THY 1 ANTIGEN;

EID: 84897058262     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4472     Document Type: Article
Times cited : (335)

References (68)
  • 2
    • 13844317894 scopus 로고    scopus 로고
    • EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
    • Kobayashi, S. et al. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. New Engl. J. Med. 352, 786-792 (2005).
    • (2005) New Engl. J. Med. , vol.352 , pp. 786-792
    • Kobayashi, S.1
  • 3
    • 33947498978 scopus 로고    scopus 로고
    • Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer
    • Sequist, L. V., Bell, D. W., Lynch, T. J. & Haber, D. A. Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer. J. Clin. Oncol. 25, 587-595 (2007).
    • (2007) J. Clin. Oncol. , vol.25 , pp. 587-595
    • Sequist, L.V.1    Bell, D.W.2    Lynch, T.J.3    Haber, D.A.4
  • 4
    • 77955928161 scopus 로고    scopus 로고
    • Tumors as organs: Complex tissues that interface with the entire organism
    • Egeblad, M., Nakasone, E. S. & Werb, Z. Tumors as organs: complex tissues that interface with the entire organism. Dev. Cell 18, 884-901 (2010).
    • (2010) Dev. Cell , vol.18 , pp. 884-901
    • Egeblad, M.1    Nakasone, E.S.2    Werb, Z.3
  • 5
    • 77955922601 scopus 로고    scopus 로고
    • Lung cancer stem cells: Tools and targets to fight lung cancer
    • Eramo, A., Haas, T. L. & De Maria, R. Lung cancer stem cells: tools and targets to fight lung cancer. Oncogene 29, 4625-4635 (2010).
    • (2010) Oncogene , vol.29 , pp. 4625-4635
    • Eramo, A.1    Haas, T.L.2    De Maria, R.3
  • 6
    • 63049104211 scopus 로고    scopus 로고
    • Microenvironmental regulation of metastasis
    • Joyce, J. A. & Pollard, J. W. Microenvironmental regulation of metastasis. Nat. Rev. Cancer 9, 239-252 (2009).
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 239-252
    • Joyce, J.A.1    Pollard, J.W.2
  • 7
  • 8
    • 84857604584 scopus 로고    scopus 로고
    • Microenvironment: Enforced compliance
    • McCarthy, N. Microenvironment: enforced compliance. Nat. Rev. Cancer 12, 152-153 (2012).
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 152-153
    • McCarthy, N.1
  • 9
    • 84859711066 scopus 로고    scopus 로고
    • Interactions between tumor cells and microenvironment in breast cancer: A new opportunity for targeted therapy
    • Mitra, S., Stemke-Hale, K., Mills, G. B. & Claerhout, S. Interactions between tumor cells and microenvironment in breast cancer: a new opportunity for targeted therapy. Cancer Sci. 103, 400-407 (2012).
    • (2012) Cancer Sci , vol.103 , pp. 400-407
    • Mitra, S.1    Stemke-Hale, K.2    Mills, G.B.3    Claerhout, S.4
  • 11
    • 84855425160 scopus 로고    scopus 로고
    • Interactions between cancer stem cells and their niche govern metastatic colonization
    • Malanchi, I. et al. Interactions between cancer stem cells and their niche govern metastatic colonization. Nature 481, 85-89 (2012).
    • (2012) Nature , vol.481 , pp. 85-89
    • Malanchi, I.1
  • 12
    • 84856087055 scopus 로고    scopus 로고
    • Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis
    • Zhang, W. C. et al. Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis. Cell 148, 259-272 (2012).
    • (2012) Cell , vol.148 , pp. 259-272
    • Zhang, W.C.1
  • 13
    • 24344506258 scopus 로고    scopus 로고
    • Cancer stem cells: Lessons from leukemia
    • Wang, J. C. & Dick, J. E. Cancer stem cells: lessons from leukemia. Trends Cell Biol. 15, 494-501 (2005).
    • (2005) Trends Cell Biol , vol.15 , pp. 494-501
    • Wang, J.C.1    Dick, J.E.2
  • 14
    • 0345059767 scopus 로고    scopus 로고
    • Applying the principles of stem-cell biology to cancer
    • Pardal, R., Clarke, M. F. & Morrison, S. J. Applying the principles of stem-cell biology to cancer. Nat. Rev. Cancer 3, 895-902 (2003).
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 895-902
    • Pardal, R.1    Clarke, M.F.2    Morrison, S.J.3
  • 15
    • 79952370202 scopus 로고    scopus 로고
    • The cancer stem cell: Premises, promises and challenges
    • Clevers, H. The cancer stem cell: premises, promises and challenges. Nat. Med. 17, 313-319 (2011).
    • (2011) Nat. Med. , vol.17 , pp. 313-319
    • Clevers, H.1
  • 16
    • 20444397431 scopus 로고    scopus 로고
    • Identification of bronchioalveolar stem cells in normal lung and lung cancer
    • Kim, C. F. et al. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 121, 823-835 (2005).
    • (2005) Cell , vol.121 , pp. 823-835
    • Kim, C.F.1
  • 17
    • 39449088496 scopus 로고    scopus 로고
    • Identification and expansion of the tumorigenic lung cancer stem cell population
    • Eramo, A. et al. Identification and expansion of the tumorigenic lung cancer stem cell population. Cell Death Differ. 15, 504-514 (2008).
    • (2008) Cell Death Differ , vol.15 , pp. 504-514
    • Eramo, A.1
  • 18
    • 34250306257 scopus 로고    scopus 로고
    • Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells
    • Ho, M. M., Ng, A. V., Lam, S. & Hung, J. Y. Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res. 67, 4827-4833 (2007).
    • (2007) Cancer Res , vol.67 , pp. 4827-4833
    • Ho, M.M.1    Ng, A.V.2    Lam, S.3    Hung, J.Y.4
  • 19
    • 51649111430 scopus 로고    scopus 로고
    • Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity
    • Vermeulen, L. et al. Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity. Proc. Natl Acad. Sci. USA 105, 13427-13432 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 13427-13432
    • Vermeulen, L.1
  • 20
    • 78649960144 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling
    • Sullivan, J. P. et al. Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling. Cancer Res. 70, 9937-9948 (2010).
    • (2010) Cancer Res , vol.70 , pp. 9937-9948
    • Sullivan, J.P.1
  • 21
    • 70349479538 scopus 로고    scopus 로고
    • Highly tumorigenic lung cancer CD133 cells display stemlike features and are spared by cisplatin treatment
    • Bertolini, G. et al. Highly tumorigenic lung cancer CD133 cells display stemlike features and are spared by cisplatin treatment. Proc. Natl Acad. Sci. USA 106, 16281-16286 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 16281-16286
    • Bertolini, G.1
  • 22
    • 1642603951 scopus 로고    scopus 로고
    • Socializing with the neighbors: Stem cells and their niche
    • Fuchs, E., Tumbar, T. & Guasch, G. Socializing with the neighbors: stem cells and their niche. Cell 116, 769-778 (2004).
    • (2004) Cell , vol.116 , pp. 769-778
    • Fuchs, E.1    Tumbar, T.2    Guasch, G.3
  • 23
    • 36749090553 scopus 로고    scopus 로고
    • Location, location, location: The cancer stem cell niche
    • Sneddon, J. B. & Werb, Z. Location, location, location: the cancer stem cell niche. Cell Stem Cell 1, 607-611 (2007).
    • (2007) Cell Stem Cell , vol.1 , pp. 607-611
    • Sneddon, J.B.1    Werb, Z.2
  • 24
    • 33745459322 scopus 로고    scopus 로고
    • Identification of pulmonary Oct-4 stem/progenitor cells and demonstration of their susceptibility to SARS coronavirus (SARS-CoV) infection in vitro
    • Ling, T. Y. et al. Identification of pulmonary Oct-4 stem/progenitor cells and demonstration of their susceptibility to SARS coronavirus (SARS-CoV) infection in vitro. Proc. Natl Acad. Sci. USA 103, 9530-9535 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 9530-9535
    • Ling, T.Y.1
  • 25
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi, K. & Yamanaka, S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676 (2006).
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 26
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson, J. A. et al. Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147 (1998).
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1
  • 27
    • 0024205842 scopus 로고
    • Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells
    • Williams, R. L. et al. Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 336, 684-687 (1988).
    • (1988) Nature , vol.336 , pp. 684-687
    • Williams, R.L.1
  • 28
    • 84879983245 scopus 로고    scopus 로고
    • Poised chromatin at the zeb1 promoter enables breast cancer cell plasticity and enhances tumorigenicity
    • Chaffer, C. L. et al. Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity. Cell 154, 61-74 (2013).
    • (2013) Cell , vol.154 , pp. 61-74
    • Chaffer, C.L.1
  • 29
    • 84872600554 scopus 로고    scopus 로고
    • Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties
    • Schwitalla, S. et al. Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties. Cell 152, 25-38 (2013).
    • (2013) Cell , vol.152 , pp. 25-38
    • Schwitalla, S.1
  • 30
    • 84880332704 scopus 로고    scopus 로고
    • The perivascular niche regulates breast tumour dormancy
    • Ghajar, C. M. et al. The perivascular niche regulates breast tumour dormancy. Nat. Cell Biol. 15, 807-817 (2013).
    • (2013) Nat. Cell Biol. , vol.15 , pp. 807-817
    • Ghajar, C.M.1
  • 32
    • 78650563018 scopus 로고    scopus 로고
    • Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
    • Kojima, Y. et al. Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts. Proc. Natl Acad. Sci. USA 107, 20009-20014 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 20009-20014
    • Kojima, Y.1
  • 33
    • 78651073833 scopus 로고    scopus 로고
    • The role of tumor stroma in cancer progression and prognosis: Emphasis on carcinoma-associated fibroblasts and non-small cell lung cancer
    • Bremnes, R. M. et al. The role of tumor stroma in cancer progression and prognosis: emphasis on carcinoma-associated fibroblasts and non-small cell lung cancer. J. Thorac. Oncol. 6, 209-217 (2011).
    • (2011) J. Thorac. Oncol. , vol.6 , pp. 209-217
    • Bremnes, R.M.1
  • 34
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/ CXCL12 secretion
    • Orimo, A. et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/ CXCL12 secretion. Cell 121, 335-348 (2005).
    • (2005) Cell , vol.121 , pp. 335-348
    • Orimo, A.1
  • 35
    • 33846531356 scopus 로고    scopus 로고
    • The tumour microenvironment as a target for chemoprevention
    • Albini, A. & Sporn, M. B. The tumour microenvironment as a target for chemoprevention. Nat. Rev. Cancer 7, 139-147 (2007).
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 139-147
    • Albini, A.1    Sporn, M.B.2
  • 36
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri, R. & Weinberg, R. A. The basics of epithelial-mesenchymal transition. J. Clin. Invest. 119, 1420-1428 (2009).
    • (2009) J. Clin. Invest. , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 37
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery, J. P., Acloque, H., Huang, R. Y. & Nieto, M. A. Epithelial-mesenchymal transitions in development and disease. Cell 139, 871-890 (2009).
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 38
    • 84858266343 scopus 로고    scopus 로고
    • Leptin mediates tumor-stromal interactions that promote the invasive growth of breast cancer cells
    • Barone, I. et al. Leptin mediates tumor-stromal interactions that promote the invasive growth of breast cancer cells. Cancer Res. 72, 1416-1427 (2012).
    • (2012) Cancer Res , vol.72 , pp. 1416-1427
    • Barone, I.1
  • 39
    • 77956280130 scopus 로고    scopus 로고
    • Reciprocal activation of prostate cancer cells and cancerassociated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness
    • Giannoni, E. et al. Reciprocal activation of prostate cancer cells and cancerassociated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness. Cancer Res. 70, 6945-6956 (2010).
    • (2010) Cancer Res , vol.70 , pp. 6945-6956
    • Giannoni, E.1
  • 40
    • 84871880164 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumors: An overview and new approaches for their isolation and characterization
    • Tirino, V. et al. Cancer stem cells in solid tumors: an overview and new approaches for their isolation and characterization. FASEB J. 27, 13-24 (2013).
    • (2013) FASEB J , vol.27 , pp. 13-24
    • Tirino, V.1
  • 41
    • 84872496776 scopus 로고    scopus 로고
    • The cancer stem cell niche(s): The crosstalk between glioma stem cells and their microenvironment
    • Filatova, A., Acker, T. & Garvalov, B. K. The cancer stem cell niche(s): The crosstalk between glioma stem cells and their microenvironment. Biochim. Biophys. Acta 1830, 2496-2508 (2013).
    • (2013) Biochim. Biophys. Acta , vol.1830 , pp. 2496-2508
    • Filatova, A.1    Acker, T.2    Garvalov, B.K.3
  • 42
    • 59849125142 scopus 로고    scopus 로고
    • SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity
    • Gangemi, R. M. et al. SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity. Stem Cells 27, 40-48 (2009).
    • (2009) Stem Cells , vol.27 , pp. 40-48
    • Gangemi, R.M.1
  • 43
    • 78650389774 scopus 로고    scopus 로고
    • Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation
    • Chiou, S. H. et al. Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation. Cancer Res. 70, 10433-10444 (2010).
    • (2010) Cancer Res , vol.70 , pp. 10433-10444
    • Chiou, S.H.1
  • 44
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
    • Visvader, J. E. & Lindeman, G. J. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat. Rev. Cancer 8, 755-768 (2008).
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 45
    • 84858608410 scopus 로고    scopus 로고
    • Cancer stem cells: Impact, heterogeneity, and uncertainty
    • Magee, J. A., Piskounova, E. & Morrison, S. J. Cancer stem cells: impact, heterogeneity, and uncertainty. Cancer Cell 21, 283-296 (2012).
    • (2012) Cancer Cell , vol.21 , pp. 283-296
    • Magee, J.A.1    Piskounova, E.2    Morrison, S.J.3
  • 46
    • 79952283482 scopus 로고    scopus 로고
    • P53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs
    • Chang, C. J. et al. p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nat. Cell Biol. 13, 317-323 (2011).
    • (2011) Nat. Cell Biol. , vol.13 , pp. 317-323
    • Chang, C.J.1
  • 47
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani, S. A. et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133, 704-715 (2008).
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1
  • 48
    • 64749091867 scopus 로고    scopus 로고
    • Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia
    • Zhao, C. et al. Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia. Nature 458, 776-779 (2009).
    • (2009) Nature , vol.458 , pp. 776-779
    • Zhao, C.1
  • 49
    • 84865555780 scopus 로고    scopus 로고
    • Nanog regulates self-renewal of cancer stem cell through IGF pathway in human hepatocellular carcinoma
    • Shan, J. et al. Nanog regulates self-renewal of cancer stem cell through IGF pathway in human hepatocellular carcinoma. Hepatology 56, 1004-1014 (2012).
    • (2012) Hepatology , vol.56 , pp. 1004-1014
    • Shan, J.1
  • 50
    • 0036714330 scopus 로고    scopus 로고
    • Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells
    • Richards, M., Fong, C. Y., Chan, W. K., Wong, P. C. & Bongso, A. Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells. Nat. Biotechnol. 20, 933-936 (2002).
    • (2002) Nat. Biotechnol. , vol.20 , pp. 933-936
    • Richards, M.1    Fong, C.Y.2    Chan, W.K.3    Wong, P.C.4    Bongso, A.5
  • 51
    • 77957350018 scopus 로고    scopus 로고
    • Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression
    • Doedens, A. L. et al. Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression. Cancer Res. 70, 7465-7475 (2010).
    • (2010) Cancer Res , vol.70 , pp. 7465-7475
    • Doedens, A.L.1
  • 52
    • 79960986355 scopus 로고    scopus 로고
    • Establishing a lung cancer stem cell culture using autologous intratumoral fibroblasts as feeder cells
    • Xu, Y., Hu, Y. D., Zhou, J. & Zhang, M. H. Establishing a lung cancer stem cell culture using autologous intratumoral fibroblasts as feeder cells. Cell Biol. Int. 35, 509-517 (2011).
    • (2011) Cell Biol. Int. , vol.35 , pp. 509-517
    • Xu, Y.1    Hu, Y.D.2    Zhou, J.3    Zhang, M.H.4
  • 53
    • 84858590826 scopus 로고    scopus 로고
    • Accessories to the crime: Functions of cells recruited to the tumor microenvironment
    • Hanahan, D. & Coussens, L. M. Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell 21, 309-322 (2012).
    • (2012) Cancer Cell , vol.21 , pp. 309-322
    • Hanahan, D.1    Coussens, L.M.2
  • 54
    • 34547162587 scopus 로고    scopus 로고
    • Concise review: No breakthroughs for human mesenchymal and embryonic stem cell culture: Conditioned medium, feeder layer, or feeder-free; Medium with fetal calf serum, human serum, or enriched plasma; Serum-free, serum replacement nonconditioned medium, or ad hoc formula? All that glitters is not gold!
    • Mannello, F. & Tonti, G. A. Concise review: no breakthroughs for human mesenchymal and embryonic stem cell culture: conditioned medium, feeder layer, or feeder-free; medium with fetal calf serum, human serum, or enriched plasma; serum-free, serum replacement nonconditioned medium, or ad hoc formula? All that glitters is not gold! Stem Cells 25, 1603-1609 (2007).
    • (2007) Stem Cells , vol.25 , pp. 1603-1609
    • Mannello, F.1    Tonti, G.A.2
  • 55
    • 79951842547 scopus 로고    scopus 로고
    • Altered TGF-beta signaling in a subpopulation of human stromal cells promotes prostatic carcinogenesis
    • Franco, O. E. et al. Altered TGF-beta signaling in a subpopulation of human stromal cells promotes prostatic carcinogenesis. Cancer Res. 71, 1272-1281 (2011).
    • (2011) Cancer Res , vol.71 , pp. 1272-1281
    • Franco, O.E.1
  • 56
    • 34548307176 scopus 로고    scopus 로고
    • IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro
    • Bendall, S. C. et al. IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro. Nature 448, 1015-1021 (2007).
    • (2007) Nature , vol.448 , pp. 1015-1021
    • Bendall, S.C.1
  • 57
    • 84856501335 scopus 로고    scopus 로고
    • The developing cancer stem-cell model: Clinical challenges and opportunities
    • Vermeulen, L., de Sousa e Melo, F., Richel, D. J. & Medema, J. P. The developing cancer stem-cell model: clinical challenges and opportunities. Lancet Oncol. 13, e83-e89 (2012).
    • (2012) Lancet Oncol. , vol.13
    • Vermeulen, L.1    Richel, D.J.2    Medema, J.P.3
  • 58
    • 0033593654 scopus 로고    scopus 로고
    • Turning brain into blood: A hematopoietic fate adopted by adult neural stem cells in vivo
    • Bjornson, C. R., Rietze, R. L., Reynolds, B. A., Magli, M. C. & Vescovi, A. L. Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo. Science 283, 534-537 (1999).
    • (1999) Science , vol.283 , pp. 534-537
    • Bjornson, C.R.1    Rietze, R.L.2    Reynolds, B.A.3    Magli, M.C.4    Vescovi, A.L.5
  • 59
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi, K. et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872 (2007).
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1
  • 60
    • 79955562722 scopus 로고    scopus 로고
    • Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer
    • Navab, R. et al. Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer. Proc. Natl Acad. Sci. USA 108, 7160-7165 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 7160-7165
    • Navab, R.1
  • 61
    • 65349160330 scopus 로고    scopus 로고
    • Isolation of stem/progenitor cells from normal lung tissue of adult humans
    • Tesei, A. et al. Isolation of stem/progenitor cells from normal lung tissue of adult humans. Cell Prolif. 42, 298-308 (2009).
    • (2009) Cell Prolif , vol.42 , pp. 298-308
    • Tesei, A.1
  • 62
    • 0037948854 scopus 로고    scopus 로고
    • In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
    • Dontu, G. et al. In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev. 17, 1253-1270 (2003).
    • (2003) Genes Dev , vol.17 , pp. 1253-1270
    • Dontu, G.1
  • 63
    • 35848955428 scopus 로고    scopus 로고
    • ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
    • Ginestier, C. et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1, 555-567 (2007).
    • (2007) Cell Stem Cell , vol.1 , pp. 555-567
    • Ginestier, C.1
  • 64
    • 0029958876 scopus 로고    scopus 로고
    • Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
    • Goodell, M. A., Brose, K., Paradis, G., Conner, A. S. & Mulligan, R. C. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J. Exp. Med. 183, 1797-1806 (1996).
    • (1996) J. Exp. Med. , vol.183 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3    Conner, A.S.4    Mulligan, R.C.5
  • 65
    • 44649120132 scopus 로고    scopus 로고
    • Chemokine signaling via the CXCR2 receptor reinforces senescence
    • Acosta, J. C. et al. Chemokine signaling via the CXCR2 receptor reinforces senescence. Cell 133, 1006-1018 (2008).
    • (2008) Cell , vol.133 , pp. 1006-1018
    • Acosta, J.C.1
  • 66
    • 79953042645 scopus 로고    scopus 로고
    • CD44: Can a cancer-initiating cell profit from an abundantly expressed molecule?
    • Zoller, M. CD44: can a cancer-initiating cell profit from an abundantly expressed molecule? Nat. Rev. Cancer 11, 254-267 (2011).
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 254-267
    • Zoller, M.1
  • 67
    • 84862550426 scopus 로고    scopus 로고
    • Novel polypyridyl chelators deplete cellular zinc and destabilize the X-linked inhibitor of apoptosis protein (XIAP) prior to induction of apoptosis in human prostate and breast cancer cells
    • Zuo, J. et al. Novel polypyridyl chelators deplete cellular zinc and destabilize the X-linked inhibitor of apoptosis protein (XIAP) prior to induction of apoptosis in human prostate and breast cancer cells. J. Cell. Biochem. 113, 2567-2575 (2012).
    • (2012) J. Cell. Biochem. , vol.113 , pp. 2567-2575
    • Zuo, J.1
  • 68
    • 0032912720 scopus 로고    scopus 로고
    • Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway
    • Wielenga, V. J. et al. Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway. Am. J. Pathol. 154, 515-523 (1999).
    • (1999) Am. J. Pathol. , vol.154 , pp. 515-523
    • Wielenga, V.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.