메뉴 건너뛰기




Volumn 25, Issue 7, 2007, Pages 1603-1609

Concise review: No breakthroughs for human mesenchymal and embryonic stem cell culture: Conditioned medium, feeder layer, or feeder-free; medium with fetal calf serum, human serum, or enriched plasma; serum-free, serum replacement nonconditioned medium, or ad hoc formula? All that glitters is not gold!

Author keywords

Autologous human serum; Embryonic stem cells; Fetal calf serum; Heterologous human serum; Mesenchymal stem cells; Platelet factor rich supernatant; Serum free medium

Indexed keywords

ALLOIMMUNITY; CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CELL MOTILITY; CELL PROLIFERATION; CELL RENEWAL; CELL THERAPY; CELL TRANSPLANTATION; CULTURE MEDIUM; EMBRYONIC STEM CELL; FETAL CALF SERUM; HISTOCOMPATIBILITY; HUMAN; IMMUNITY; MESENCHYMAL STEM CELL; NONHUMAN; PLURIPOTENT STEM CELL; SHORT SURVEY;

EID: 34547162587     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2007-0127     Document Type: Short Survey
Times cited : (260)

References (89)
  • 1
    • 33745266607 scopus 로고    scopus 로고
    • Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells
    • Sotiropoulou PA, Perez SA, Salagianni M et al. Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells. STEM CELLS 2006;24:462-471.
    • (2006) STEM CELLS , vol.24 , pp. 462-471
    • Sotiropoulou, P.A.1    Perez, S.A.2    Salagianni, M.3
  • 2
    • 33750081777 scopus 로고    scopus 로고
    • FDA regulation of stem-cell-based therapies
    • Halme DG, Kessler DA. FDA regulation of stem-cell-based therapies. New Engl J Med 2006;355:1730-1735.
    • (2006) New Engl J Med , vol.355 , pp. 1730-1735
    • Halme, D.G.1    Kessler, D.A.2
  • 3
    • 27144541524 scopus 로고    scopus 로고
    • In vitro expansion of human mesenchymal stem cells: Choice of serum is a determinant of cell proliferation, differentiation, gene expression, and transcriptome stability
    • Shahdadfar A, Tronsdal K, Haug T et al. In vitro expansion of human mesenchymal stem cells: Choice of serum is a determinant of cell proliferation, differentiation, gene expression, and transcriptome stability. STEM CELLS 2005;23:1357-1366.
    • (2005) STEM CELLS , vol.23 , pp. 1357-1366
    • Shahdadfar, A.1    Tronsdal, K.2    Haug, T.3
  • 4
    • 33846026308 scopus 로고    scopus 로고
    • Cell culture medium composition and translational adult bone marrow-derived stem cell research
    • Berger MG, Veyrat-Masson R, Rapatel C et al. Cell culture medium composition and translational adult bone marrow-derived stem cell research. STEM CELLS 2006;24:2888-2890.
    • (2006) STEM CELLS , vol.24 , pp. 2888-2890
    • Berger, M.G.1    Veyrat-Masson, R.2    Rapatel, C.3
  • 5
    • 2442464824 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Paradoxes of passaging
    • Javazon EH, Beggs KJ, Flake AW. Mesenchymal stem cells: Paradoxes of passaging. Exp Hematol 2004;32:414-425.
    • (2004) Exp Hematol , vol.32 , pp. 414-425
    • Javazon, E.H.1    Beggs, K.J.2    Flake, A.W.3
  • 6
    • 1242276404 scopus 로고    scopus 로고
    • Feeder layer- and serum-free culture of human embryonic stem cells
    • Amit M, Shariki C, Margulets V et al. Feeder layer- and serum-free culture of human embryonic stem cells. Biol Reprod 2004;70:837-845.
    • (2004) Biol Reprod , vol.70 , pp. 837-845
    • Amit, M.1    Shariki, C.2    Margulets, V.3
  • 7
    • 24644506123 scopus 로고    scopus 로고
    • Expansion of human embryonic stem cells in defined serum-free medium devoid of animal-derived products
    • Li Y, Powell S, Brunette E et al. Expansion of human embryonic stem cells in defined serum-free medium devoid of animal-derived products. Biotechnol Bioeng 2005;91:688-698.
    • (2005) Biotechnol Bioeng , vol.91 , pp. 688-698
    • Li, Y.1    Powell, S.2    Brunette, E.3
  • 8
    • 32444441394 scopus 로고    scopus 로고
    • The medium is the message
    • Moore H. The medium is the message. Nat Biotechnol 2006;24:160-161.
    • (2006) Nat Biotechnol , vol.24 , pp. 160-161
    • Moore, H.1
  • 9
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson JA, Itskowitz-Eldor J, Saphiro SS et al. Embryonic stem cell lines derived from human blastocysts. Science 1998;282:1145-1147.
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1    Itskowitz-Eldor, J.2    Saphiro, S.S.3
  • 10
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981;292:154-156.
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 11
    • 0024245022 scopus 로고
    • Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides
    • Smith AG, Heath JK, Donaldson DD et al. Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature 1988;336:688-690.
    • (1988) Nature , vol.336 , pp. 688-690
    • Smith, A.G.1    Heath, J.K.2    Donaldson, D.D.3
  • 12
    • 0344738990 scopus 로고    scopus 로고
    • Establishment and maintenance of human embryonic stem cells on STO, a permanently growing cell line
    • Park JH, Kim SJ, Oh EJ et al. Establishment and maintenance of human embryonic stem cells on STO, a permanently growing cell line. Biol Reprod 2003;69:2007-2014.
    • (2003) Biol Reprod , vol.69 , pp. 2007-2014
    • Park, J.H.1    Kim, S.J.2    Oh, E.J.3
  • 13
    • 15544375987 scopus 로고    scopus 로고
    • An autogenic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells
    • Stojkovic P, Lako M, Stewart R et al. An autogenic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells. STEM CELLS 2005;23:306-314.
    • (2005) STEM CELLS , vol.23 , pp. 306-314
    • Stojkovic, P.1    Lako, M.2    Stewart, R.3
  • 14
    • 34547197977 scopus 로고    scopus 로고
    • Information and recommendations for physicians involved in the coculture of human embryos with nonhuman animal cells. Food and Drug Administration Web site. Available at:, Accessed March 5, 2007
    • Information and recommendations for physicians involved in the coculture of human embryos with nonhuman animal cells. Food and Drug Administration Web site. Available at: http://www.fda.gov/cber/infosheets/humembclin.htm. Accessed March 5, 2007.
  • 15
    • 0036744406 scopus 로고    scopus 로고
    • Proteome analysis of conditioned medium from mouse embryonic fibroblast feeder layers which support the growth of human embryonic stem cells
    • Lim JW, Bodnar A. Proteome analysis of conditioned medium from mouse embryonic fibroblast feeder layers which support the growth of human embryonic stem cells. Proteomics 2002;2:1187-1203.
    • (2002) Proteomics , vol.2 , pp. 1187-1203
    • Lim, J.W.1    Bodnar, A.2
  • 16
    • 18744375483 scopus 로고    scopus 로고
    • Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells
    • Xu RH, Peck RM, Li DS et al. Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells. Nat Methods 2005;2:185-190.
    • (2005) Nat Methods , vol.2 , pp. 185-190
    • Xu, R.H.1    Peck, R.M.2    Li, D.S.3
  • 17
    • 0345688742 scopus 로고    scopus 로고
    • Comparative evaluation of various human feeders for prolonged undifferentiated growth of human embryonic stem cells
    • Richards M, Tan S, Fong CY et al. Comparative evaluation of various human feeders for prolonged undifferentiated growth of human embryonic stem cells. STEM CELLS 2003;21:546-556.
    • (2003) STEM CELLS , vol.21 , pp. 546-556
    • Richards, M.1    Tan, S.2    Fong, C.Y.3
  • 18
    • 10744225452 scopus 로고    scopus 로고
    • A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells
    • Hovatta O, Mikkola M, Gertow K et al. A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells. Hum Reprod 2003;18:1404-1409.
    • (2003) Hum Reprod , vol.18 , pp. 1404-1409
    • Hovatta, O.1    Mikkola, M.2    Gertow, K.3
  • 19
    • 0034794417 scopus 로고    scopus 로고
    • Feeder-free growth of undifferentiated human embryonic stem cells
    • Xu C, Inokuma MS, Denham J et al. Feeder-free growth of undifferentiated human embryonic stem cells. Nat Biotechnol 2001;19:971-974.
    • (2001) Nat Biotechnol , vol.19 , pp. 971-974
    • Xu, C.1    Inokuma, M.S.2    Denham, J.3
  • 20
    • 18744401357 scopus 로고    scopus 로고
    • Human embryonic stem cells derived without feeder cells
    • Klimanskaya I, Chung Y, Meisner L et al. Human embryonic stem cells derived without feeder cells. Lancet 2005;365:1636-1641.
    • (2005) Lancet , vol.365 , pp. 1636-1641
    • Klimanskaya, I.1    Chung, Y.2    Meisner, L.3
  • 21
    • 0032127977 scopus 로고    scopus 로고
    • Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
    • Niwa H, Burdon T, Chambers I et al. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev 1998;12:2048-2060.
    • (1998) Genes Dev , vol.12 , pp. 2048-2060
    • Niwa, H.1    Burdon, T.2    Chambers, I.3
  • 22
    • 0027429221 scopus 로고
    • Ciliary neurotrophic factor maintains the pluripotentiality of embryonic stem cells
    • Conover JC, Ip NY, Poueymirou WT et al. Ciliary neurotrophic factor maintains the pluripotentiality of embryonic stem cells. Development 1993;119:559-565.
    • (1993) Development , vol.119 , pp. 559-565
    • Conover, J.C.1    Ip, N.Y.2    Poueymirou, W.T.3
  • 23
    • 20144380595 scopus 로고    scopus 로고
    • Basic fibroblast growth factor supports undifferentiated human embryonic stem cell growth without conditioned medium
    • Xu C, Rosler E, Jiang J et al. Basic fibroblast growth factor supports undifferentiated human embryonic stem cell growth without conditioned medium. STEM CELLS 2005;23:315-323.
    • (2005) STEM CELLS , vol.23 , pp. 315-323
    • Xu, C.1    Rosler, E.2    Jiang, J.3
  • 24
    • 19644367664 scopus 로고    scopus 로고
    • Synthetic biomaterial as instructive extracellular microenvironments for morphogenesis in tissue engineering
    • Lutolf MP, Hubbell JA. Synthetic biomaterial as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat Biotechnol 2005;23:47-55.
    • (2005) Nat Biotechnol , vol.23 , pp. 47-55
    • Lutolf, M.P.1    Hubbell, J.A.2
  • 25
    • 23244435467 scopus 로고    scopus 로고
    • How do stem cells find their way home?
    • Lapidot T, Dar A, Kollet O. How do stem cells find their way home? Blood 2005;106:1901-1910.
    • (2005) Blood , vol.106 , pp. 1901-1910
    • Lapidot, T.1    Dar, A.2    Kollet, O.3
  • 26
    • 13844267152 scopus 로고    scopus 로고
    • Human embryonic stem cells express an immunogenic nonhuman sialic acid
    • Martin MJ, Muotri A, Gage F et al. Human embryonic stem cells express an immunogenic nonhuman sialic acid. Nat Med 2005;11:228-232.
    • (2005) Nat Med , vol.11 , pp. 228-232
    • Martin, M.J.1    Muotri, A.2    Gage, F.3
  • 27
    • 33845999239 scopus 로고    scopus 로고
    • N-glycolylneuraminic acid xenoantigen contamination of human embryonic and mesenchymal stem cells is substantially reversible
    • Heiskanen A, Satomaa T, Tiitinen S et al. N-glycolylneuraminic acid xenoantigen contamination of human embryonic and mesenchymal stem cells is substantially reversible. STEM CELLS 2007;25:197-202.
    • (2007) STEM CELLS , vol.25 , pp. 197-202
    • Heiskanen, A.1    Satomaa, T.2    Tiitinen, S.3
  • 28
    • 33645527040 scopus 로고    scopus 로고
    • Unique gene expression signature by human embryonic stem cells cultured under serum-free conditions correlates with their enhanced and prolonged growth in an undifferentiated stage
    • Skottman H, Stromberg AM, Matilainen E et al. Unique gene expression signature by human embryonic stem cells cultured under serum-free conditions correlates with their enhanced and prolonged growth in an undifferentiated stage. STEM CELLS 2006;24:151-167.
    • (2006) STEM CELLS , vol.24 , pp. 151-167
    • Skottman, H.1    Stromberg, A.M.2    Matilainen, E.3
  • 29
    • 23844556152 scopus 로고    scopus 로고
    • Human-serum matrix supports undifferentiated growth of human embryonic stem cells
    • Stojkovic P, Lako M, Przyborski S et al. Human-serum matrix supports undifferentiated growth of human embryonic stem cells. STEM CELLS 2005;23:895-902.
    • (2005) STEM CELLS , vol.23 , pp. 895-902
    • Stojkovic, P.1    Lako, M.2    Przyborski, S.3
  • 30
    • 34447103025 scopus 로고    scopus 로고
    • Testing of nine different xeno-free culture media for human embryonic stem cell cultures
    • in press
    • Rajala K, Hakala H, Panula S et al. Testing of nine different xeno-free culture media for human embryonic stem cell cultures. Hum Reprod 2007 (in press).
    • (2007) Hum Reprod
    • Rajala, K.1    Hakala, H.2    Panula, S.3
  • 31
    • 33744975168 scopus 로고    scopus 로고
    • In vitro culture conditions favouring selection of chromosomal abnormalities in human ES cells
    • Imreh MP, Gertow K, Cedervall J et al. In vitro culture conditions favouring selection of chromosomal abnormalities in human ES cells. J Cell Biochem 2006;99:508-516.
    • (2006) J Cell Biochem , vol.99 , pp. 508-516
    • Imreh, M.P.1    Gertow, K.2    Cedervall, J.3
  • 32
    • 33846910469 scopus 로고    scopus 로고
    • Sarcoma derived from cultured mesenchymal stem cells
    • Tolar J, Nauta AJ, Osborn MJ et al. Sarcoma derived from cultured mesenchymal stem cells. STEM CELLS 2007;25:371-379.
    • (2007) STEM CELLS , vol.25 , pp. 371-379
    • Tolar, J.1    Nauta, A.J.2    Osborn, M.J.3
  • 34
    • 33750019223 scopus 로고    scopus 로고
    • Proteomic analysis for the assessment of different lots of fetal bovine serum as a raw material for cell culture. Part IV. Application of proteomics to the manufacture of biological drugs
    • Zheng X, Baker H, Hancock WS et al. Proteomic analysis for the assessment of different lots of fetal bovine serum as a raw material for cell culture. Part IV. Application of proteomics to the manufacture of biological drugs. Biotechnol Prog 2006;22:1294-1300.
    • (2006) Biotechnol Prog , vol.22 , pp. 1294-1300
    • Zheng, X.1    Baker, H.2    Hancock, W.S.3
  • 35
    • 2442713904 scopus 로고    scopus 로고
    • Internalized antigen must be removed to prepare hypoimmunogenic mesenchymal stem cells for cell and gene therapy
    • Spees JL, Gregory CA, Singh H et al. Internalized antigen must be removed to prepare hypoimmunogenic mesenchymal stem cells for cell and gene therapy. Mol Ther 2004;9:747-756.
    • (2004) Mol Ther , vol.9 , pp. 747-756
    • Spees, J.L.1    Gregory, C.A.2    Singh, H.3
  • 36
    • 0031407119 scopus 로고    scopus 로고
    • Medicinal and other products and human and animal transmissible spongiform encephalopathies: Memorandum from a WHO meeting
    • Medicinal and other products and human and animal transmissible spongiform encephalopathies: Memorandum from a WHO meeting. Bull World Health Organ 1997;75:505-513.
    • (1997) Bull World Health Organ , vol.75 , pp. 505-513
  • 37
    • 0030892087 scopus 로고    scopus 로고
    • Development of antibodies to fetal calf serum with arthus-like reactions in human immunodeficiency virus-infected patients given syngeneic lymphocytes infusions
    • Selvaggi TA, Walker RE, Fleisher TA. Development of antibodies to fetal calf serum with arthus-like reactions in human immunodeficiency virus-infected patients given syngeneic lymphocytes infusions. Blood 1997;89:776-779.
    • (1997) Blood , vol.89 , pp. 776-779
    • Selvaggi, T.A.1    Walker, R.E.2    Fleisher, T.A.3
  • 38
    • 4444223807 scopus 로고    scopus 로고
    • Autologous human serum for cell culture avoids the implantation of cardioverter-defibrillator in cellular cardiomyoplasty
    • Chachques JC, Herreros J, Trainini J et al. Autologous human serum for cell culture avoids the implantation of cardioverter-defibrillator in cellular cardiomyoplasty. Int J Cardiol 2004;95(suppl 1):S29-S33.
    • (2004) Int J Cardiol , vol.95 , Issue.SUPPL. 1
    • Chachques, J.C.1    Herreros, J.2    Trainini, J.3
  • 39
    • 3042662157 scopus 로고    scopus 로고
    • Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarction
    • Chen SJ, Fang WW, Ye F et al. Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarction. Am J Cardiol 2004;94:92-95.
    • (2004) Am J Cardiol , vol.94 , pp. 92-95
    • Chen, S.J.1    Fang, W.W.2    Ye, F.3
  • 40
    • 21244442301 scopus 로고    scopus 로고
    • Transcoronary transplantation of autologous mesenchymal stem cells and endothelial progenitors into infarcted human myocardium
    • Katritsis DG, Sotiropoulou PA, Karvouni E et al. Transcoronary transplantation of autologous mesenchymal stem cells and endothelial progenitors into infarcted human myocardium. Catheter Cardiovasc Interv 2005;65:321-329.
    • (2005) Catheter Cardiovasc Interv , vol.65 , pp. 321-329
    • Katritsis, D.G.1    Sotiropoulou, P.A.2    Karvouni, E.3
  • 41
    • 0036376741 scopus 로고    scopus 로고
    • Immune response to fetal calf serum by two adenosine deaminase-deficient patients after T cell gene therapy
    • Tuschong L, Soenen SL, Blaese RM et al. Immune response to fetal calf serum by two adenosine deaminase-deficient patients after T cell gene therapy. Hum Gene Ther 2002;13:1605-1610.
    • (2002) Hum Gene Ther , vol.13 , pp. 1605-1610
    • Tuschong, L.1    Soenen, S.L.2    Blaese, R.M.3
  • 42
    • 33748304106 scopus 로고    scopus 로고
    • Differences in the effect on neural stem cells of fetal bovine serum in substrate-coated and soluble form
    • Hung CH, Young TH. Differences in the effect on neural stem cells of fetal bovine serum in substrate-coated and soluble form. Biomaterials 2006;27:5901-5908.
    • (2006) Biomaterials , vol.27 , pp. 5901-5908
    • Hung, C.H.1    Young, T.H.2
  • 43
    • 3542992675 scopus 로고    scopus 로고
    • Effects of serum and serum heat-inactivation on human bone derived osteoblast progenitor cells
    • Bruinink A, Tobler U, Halg M et al. Effects of serum and serum heat-inactivation on human bone derived osteoblast progenitor cells. J Mater Sci Mater Med 2004;15:497-501.
    • (2004) J Mater Sci Mater Med , vol.15 , pp. 497-501
    • Bruinink, A.1    Tobler, U.2    Halg, M.3
  • 44
    • 0036235036 scopus 로고    scopus 로고
    • Comparative analysis of foetal calf and human low density lipoprotein: Relevance for pharmacodynamics of photosensitizers
    • Haylett AK, Moore JV. Comparative analysis of foetal calf and human low density lipoprotein: Relevance for pharmacodynamics of photosensitizers. J Photochem Photobiol B 2002;66:171-178.
    • (2002) J Photochem Photobiol B , vol.66 , pp. 171-178
    • Haylett, A.K.1    Moore, J.V.2
  • 45
    • 0023202224 scopus 로고
    • Effects of age, obesity and growth-hormone on adipogenic activity in human plasma
    • Sypniewska G, Xu XF, Hager A et al. Effects of age, obesity and growth-hormone on adipogenic activity in human plasma. Int J Obes 1987;11:263-273.
    • (1987) Int J Obes , vol.11 , pp. 263-273
    • Sypniewska, G.1    Xu, X.F.2    Hager, A.3
  • 46
    • 0028858046 scopus 로고
    • Foetal calf serum in growth medium obscures the detection of early anticardiolipin antibody secreting clones
    • Menon S, Isenberg DA. Foetal calf serum in growth medium obscures the detection of early anticardiolipin antibody secreting clones. J Immunol Methods 1995;186:65-70.
    • (1995) J Immunol Methods , vol.186 , pp. 65-70
    • Menon, S.1    Isenberg, D.A.2
  • 47
    • 0031674527 scopus 로고    scopus 로고
    • Functional comparison of bovine, murine, and human beta2-microglobulin: Interactions with murine MHC I molecules
    • Shields MJ, Moffat LE, Ribaudo RK. Functional comparison of bovine, murine, and human beta2-microglobulin: Interactions with murine MHC I molecules. Mol Immunol 1998;35:919-928.
    • (1998) Mol Immunol , vol.35 , pp. 919-928
    • Shields, M.J.1    Moffat, L.E.2    Ribaudo, R.K.3
  • 48
    • 33947501079 scopus 로고    scopus 로고
    • Comparative analysis of in vitro conditions for rat adult neural progenitor cells
    • Dictus C, Tronnier V, Unterberg A et al. Comparative analysis of in vitro conditions for rat adult neural progenitor cells. J Neurosci Methods 2007;161:250-258.
    • (2007) J Neurosci Methods , vol.161 , pp. 250-258
    • Dictus, C.1    Tronnier, V.2    Unterberg, A.3
  • 49
    • 0026688452 scopus 로고
    • Fetuin: Its enigmatic property of growth promotion
    • Nie Z. Fetuin: Its enigmatic property of growth promotion. Am J Physiol 1992;263:C551-C562.
    • (1992) Am J Physiol , vol.263
    • Nie, Z.1
  • 51
    • 33947426513 scopus 로고    scopus 로고
    • Proteolytic processing by matrix metalloproteinases and phosphorylation by protein kinase CK2 of fetuin-A, the major globulin of fetal calf serum
    • Kubler D, Gosenca D, Wind M et al. Proteolytic processing by matrix metalloproteinases and phosphorylation by protein kinase CK2 of fetuin-A, the major globulin of fetal calf serum. Biochimie 2007;89:410-418.
    • (2007) Biochimie , vol.89 , pp. 410-418
    • Kubler, D.1    Gosenca, D.2    Wind, M.3
  • 52
    • 33646540257 scopus 로고    scopus 로고
    • Role and function of matrix metalloproteinases in the differentiation and biological characterisation of mesenchymal stem cells
    • Mannello F, Tonti GA, Bagnara GP et al. Role and function of matrix metalloproteinases in the differentiation and biological characterisation of mesenchymal stem cells. STEM CELLS 2006;24:475-481.
    • (2006) STEM CELLS , vol.24 , pp. 475-481
    • Mannello, F.1    Tonti, G.A.2    Bagnara, G.P.3
  • 53
    • 33749160336 scopus 로고    scopus 로고
    • Multipotent mesenchymal stromal cell recruitment, migration, and differentiation: What have matrix metalloproteinases got to do with it?
    • Mannello F. Multipotent mesenchymal stromal cell recruitment, migration, and differentiation: What have matrix metalloproteinases got to do with it? STEM CELLS 2006;24:1904-1907.
    • (2006) STEM CELLS , vol.24 , pp. 1904-1907
    • Mannello, F.1
  • 54
    • 33749077553 scopus 로고    scopus 로고
    • Cell culture medium composition and translational adult bone marrow-derived stem cell research
    • Dimarakis I, Levicar N. Cell culture medium composition and translational adult bone marrow-derived stem cell research. STEM CELLS 2006;24:1407-1408.
    • (2006) STEM CELLS , vol.24 , pp. 1407-1408
    • Dimarakis, I.1    Levicar, N.2
  • 55
    • 0036456669 scopus 로고    scopus 로고
    • Expansion of human adult stem cells from bone marrow stroma: Conditions that maximize the yields of early progenitors and evaluate their quality
    • Sekiya I, Larson BL, Smith JR et al. Expansion of human adult stem cells from bone marrow stroma: Conditions that maximize the yields of early progenitors and evaluate their quality. STEM CELLS 2002;20:530-541.
    • (2002) STEM CELLS , vol.20 , pp. 530-541
    • Sekiya, I.1    Larson, B.L.2    Smith, J.R.3
  • 56
    • 33749040895 scopus 로고    scopus 로고
    • Cell culture medium composition and translational adult bone marrow-derived stem cell research
    • Sotiropoulou PA, Perez SA, Salagianni M et al. Cell culture medium composition and translational adult bone marrow-derived stem cell research. STEM CELLS 2006;24:1409-1410.
    • (2006) STEM CELLS , vol.24 , pp. 1409-1410
    • Sotiropoulou, P.A.1    Perez, S.A.2    Salagianni, M.3
  • 57
    • 33746006530 scopus 로고    scopus 로고
    • Serofendic acid, a neuroprotective substance derived from fetal calf serum, inhibit mitochondrial depolarization and caspase-3 activation
    • Kume T, Taguchi R, Katsuki H et al. Serofendic acid, a neuroprotective substance derived from fetal calf serum, inhibit mitochondrial depolarization and caspase-3 activation. Eur J Pharmacol 2006;542:69-76.
    • (2006) Eur J Pharmacol , vol.542 , pp. 69-76
    • Kume, T.1    Taguchi, R.2    Katsuki, H.3
  • 58
    • 33847652908 scopus 로고    scopus 로고
    • Optimization of in vitro expansion of human multipotent mesenchymal stromal cells for celltherapy approaches: Further insight in the search for a fetal calf serum substitute
    • Bernardo ME, Avanzini MA, Perotti C et al. Optimization of in vitro expansion of human multipotent mesenchymal stromal cells for celltherapy approaches: Further insight in the search for a fetal calf serum substitute. J Cell Physiol 2007;211:121-130.
    • (2007) J Cell Physiol , vol.211 , pp. 121-130
    • Bernardo, M.E.1    Avanzini, M.A.2    Perotti, C.3
  • 59
    • 0036196461 scopus 로고    scopus 로고
    • Human marrow-derived mesenchymal progenitor cells: Isolation culture, expansion and analysis of differentiation
    • Caterson EJ, Nesti LJ, Danielson KG et al. Human marrow-derived mesenchymal progenitor cells: Isolation culture, expansion and analysis of differentiation. Mol Biotechnol 2002;20:245-256.
    • (2002) Mol Biotechnol , vol.20 , pp. 245-256
    • Caterson, E.J.1    Nesti, L.J.2    Danielson, K.G.3
  • 60
    • 4544233730 scopus 로고    scopus 로고
    • Culture and characterisation of human embryonic stem cells
    • Draper JS, Moore HD, Ruban NN et al. Culture and characterisation of human embryonic stem cells. Stem Cells Dev 2004;13:325-336.
    • (2004) Stem Cells Dev , vol.13 , pp. 325-336
    • Draper, J.S.1    Moore, H.D.2    Ruban, N.N.3
  • 61
    • 33646541710 scopus 로고    scopus 로고
    • The derivation of clinical grade human embryonic stem cell lines
    • Skottman H, Dilber MS, Hovatta O. The derivation of clinical grade human embryonic stem cell lines. FEBS Lett 2006;580:2875-2878.
    • (2006) FEBS Lett , vol.580 , pp. 2875-2878
    • Skottman, H.1    Dilber, M.S.2    Hovatta, O.3
  • 62
    • 0030705161 scopus 로고    scopus 로고
    • Modulation of osteogenesis and adipogenesis by human serum in human bone marrow cultures
    • Oreffo RO, Virdi AS, Triffitt JT. Modulation of osteogenesis and adipogenesis by human serum in human bone marrow cultures. Eur J Cell Biol 1997;74:251-261.
    • (1997) Eur J Cell Biol , vol.74 , pp. 251-261
    • Oreffo, R.O.1    Virdi, A.S.2    Triffitt, J.T.3
  • 63
    • 0037534405 scopus 로고    scopus 로고
    • Effects of autologous serum on osteoblastic differentiation in human bone marrow cells
    • Yamamoto N, Isobe M, Negishi A et al. Effects of autologous serum on osteoblastic differentiation in human bone marrow cells. J Med Dent Sci 2003;50:63-69.
    • (2003) J Med Dent Sci , vol.50 , pp. 63-69
    • Yamamoto, N.1    Isobe, M.2    Negishi, A.3
  • 64
    • 10044230580 scopus 로고    scopus 로고
    • Autologous serum for isolation and expansion of human mesenchymal stem cells for clinical use
    • Stute N, Holtz K, Bubenheim M et al. Autologous serum for isolation and expansion of human mesenchymal stem cells for clinical use. Exp Hematol 2004;32:1212-1225.
    • (2004) Exp Hematol , vol.32 , pp. 1212-1225
    • Stute, N.1    Holtz, K.2    Bubenheim, M.3
  • 65
    • 29544446897 scopus 로고    scopus 로고
    • Using human plasma supplemented medium to cultivated human bone marrow-derived mesenchymal stem cell and evaluation of its multiple-lineage potential
    • Lin HT, Tarng YW, Chen YC et al. Using human plasma supplemented medium to cultivated human bone marrow-derived mesenchymal stem cell and evaluation of its multiple-lineage potential. Transplant Proc 2005;37:4504-4505.
    • (2005) Transplant Proc , vol.37 , pp. 4504-4505
    • Lin, H.T.1    Tarng, Y.W.2    Chen, Y.C.3
  • 66
    • 27244433268 scopus 로고    scopus 로고
    • Motility and growth of human bone-marrow mesenchymal stem cells during ex-vivo expansion in autologous serum
    • Kobayashi T, Watanabe H, Yanagawa T et al. Motility and growth of human bone-marrow mesenchymal stem cells during ex-vivo expansion in autologous serum. J Bone Joint Surg Br 2005;87:1426-1433.
    • (2005) J Bone Joint Surg Br , vol.87 , pp. 1426-1433
    • Kobayashi, T.1    Watanabe, H.2    Yanagawa, T.3
  • 67
    • 33749524824 scopus 로고    scopus 로고
    • Enhanced engraftment of mesenchymal stem cells in a cutaneous wound model by culture in allogeneic species-specific serum and administration in fibrin constructs
    • Gregory CA, Reyes E, Whitney MJ et al. Enhanced engraftment of mesenchymal stem cells in a cutaneous wound model by culture in allogeneic species-specific serum and administration in fibrin constructs. STEM CELLS 2006;24:2232-2243.
    • (2006) STEM CELLS , vol.24 , pp. 2232-2243
    • Gregory, C.A.1    Reyes, E.2    Whitney, M.J.3
  • 68
    • 33744728985 scopus 로고    scopus 로고
    • Human autologous serum obtained using a completely closed bag system as a substitute for foetal calf serum in human mesenchymal stem cell cultures
    • Mizuno N, Shiba H, Ozeki Y et al. Human autologous serum obtained using a completely closed bag system as a substitute for foetal calf serum in human mesenchymal stem cell cultures. Cell Biol Int 2006;30:521-524.
    • (2006) Cell Biol Int , vol.30 , pp. 521-524
    • Mizuno, N.1    Shiba, H.2    Ozeki, Y.3
  • 69
    • 18744362206 scopus 로고    scopus 로고
    • Bone marrow stromal cells prepared using AB serum and bFGF for hematopoietic stem cell expansion
    • Yamaguchi M, Hirayama F, Wakamoto S et al. Bone marrow stromal cells prepared using AB serum and bFGF for hematopoietic stem cell expansion. Transfusion 2002;42:921-927.
    • (2002) Transfusion , vol.42 , pp. 921-927
    • Yamaguchi, M.1    Hirayama, F.2    Wakamoto, S.3
  • 70
    • 0036893541 scopus 로고    scopus 로고
    • In vitro control of human bone marrow stromal cells for bone tissue engineering
    • Anselme K, Broux O, Noel B et al. In vitro control of human bone marrow stromal cells for bone tissue engineering. Tissue Eng 2002;8:941-953.
    • (2002) Tissue Eng , vol.8 , pp. 941-953
    • Anselme, K.1    Broux, O.2    Noel, B.3
  • 71
    • 0034722911 scopus 로고    scopus 로고
    • Effect of serum on human bone marrow stromal cells: Ex vivo expansion and in vivo bone formation
    • Kuznetsov SA, Mankani MH, Robey PG. Effect of serum on human bone marrow stromal cells: Ex vivo expansion and in vivo bone formation. Transplantation 2000;70:1780-1787.
    • (2000) Transplantation , vol.70 , pp. 1780-1787
    • Kuznetsov, S.A.1    Mankani, M.H.2    Robey, P.G.3
  • 72
    • 33750195530 scopus 로고    scopus 로고
    • Animal serum-free culture conditions for isolation and expansion of multipotent mesenchymal stromal cells from human BM
    • Muller I, Kordowich S, Holzwarth C et al. Animal serum-free culture conditions for isolation and expansion of multipotent mesenchymal stromal cells from human BM. Cytotherapy 2006;8:437-444.
    • (2006) Cytotherapy , vol.8 , pp. 437-444
    • Muller, I.1    Kordowich, S.2    Holzwarth, C.3
  • 73
    • 16644395948 scopus 로고    scopus 로고
    • Effects of platelet growth factors on human mesenchymal stem cells and human endothelial cells in vitro
    • Kilian O, Flesch I, Wenisch S et al. Effects of platelet growth factors on human mesenchymal stem cells and human endothelial cells in vitro. Eur J Med Res 2004;9:337-344.
    • (2004) Eur J Med Res , vol.9 , pp. 337-344
    • Kilian, O.1    Flesch, I.2    Wenisch, S.3
  • 74
    • 1442290154 scopus 로고    scopus 로고
    • Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow-derived mesenchymal progenitors cells under in vitro conditions
    • Gruber R, Karreth F, Kandler B et al. Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow-derived mesenchymal progenitors cells under in vitro conditions. Platelets 2004;15:29-35.
    • (2004) Platelets , vol.15 , pp. 29-35
    • Gruber, R.1    Karreth, F.2    Kandler, B.3
  • 75
    • 21244476175 scopus 로고    scopus 로고
    • Platelet lysates promote mesenchymal stem cell expansion: A safety substitute for animal serum in cell-based therapy applications
    • Doucet C, Ernou I, Zhang Y et al. Platelet lysates promote mesenchymal stem cell expansion: A safety substitute for animal serum in cell-based therapy applications. J Cell Physiol 2005;205:228-236.
    • (2005) J Cell Physiol , vol.205 , pp. 228-236
    • Doucet, C.1    Ernou, I.2    Zhang, Y.3
  • 76
    • 33750515870 scopus 로고    scopus 로고
    • Platelet-rich plasma improves expansion of human mesenchymal stem cells and retains differentiation capacity and in vivo bone formation in calcium phosphate ceramics
    • Vogel JP, Szalay K, Geiger F et al. Platelet-rich plasma improves expansion of human mesenchymal stem cells and retains differentiation capacity and in vivo bone formation in calcium phosphate ceramics. Platelets 2006;17:462-469.
    • (2006) Platelets , vol.17 , pp. 462-469
    • Vogel, J.P.1    Szalay, K.2    Geiger, F.3
  • 77
    • 34247602975 scopus 로고    scopus 로고
    • Human AB-serum as well as thrombin-activated platelet-rich-plasma are suitable alternatives to fetal calf serum for the expansion of mesenchymal stem cells from adipose tissue
    • Kocaoemer A, Kern S, Klueter H et al. Human AB-serum as well as thrombin-activated platelet-rich-plasma are suitable alternatives to fetal calf serum for the expansion of mesenchymal stem cells from adipose tissue. STEM CELLS 2007;25:1270-1278.
    • (2007) STEM CELLS , vol.25 , pp. 1270-1278
    • Kocaoemer, A.1    Kern, S.2    Klueter, H.3
  • 78
    • 10944233539 scopus 로고    scopus 로고
    • Establishment and maintenance of human embryonic stem cell lines on human feeder cells derived from uterine endometrium under serum-free condition
    • Lee JB, Lee JE, Park JH et al. Establishment and maintenance of human embryonic stem cell lines on human feeder cells derived from uterine endometrium under serum-free condition. Biol Reprod 2005;72:42-49.
    • (2005) Biol Reprod , vol.72 , pp. 42-49
    • Lee, J.B.1    Lee, J.E.2    Park, J.H.3
  • 79
    • 33845195258 scopus 로고    scopus 로고
    • Feeder-free culture of human embryonic stem cells
    • Amit M, Itskovitz-Eldor J. Feeder-free culture of human embryonic stem cells. Methods Enzymol 2006;420:37-49.
    • (2006) Methods Enzymol , vol.420 , pp. 37-49
    • Amit, M.1    Itskovitz-Eldor, J.2
  • 80
    • 29144442975 scopus 로고    scopus 로고
    • Serum-free medium cultivation to improve efficacy in establishment of human embryonic stem cell lines
    • Hong-mei P, Gui-an C. Serum-free medium cultivation to improve efficacy in establishment of human embryonic stem cell lines. Hum Reprod 2006;21:217-222.
    • (2006) Hum Reprod , vol.21 , pp. 217-222
    • Hong-mei, P.1    Gui-an, C.2
  • 81
    • 33846515388 scopus 로고    scopus 로고
    • Derivation, characterization and differentiation of human embryonic stem cells: Comparing serum-containing versus serum-free media and evidence of germ cell differentiation
    • Chen HF, Kuo HC, Chien CL et al. Derivation, characterization and differentiation of human embryonic stem cells: Comparing serum-containing versus serum-free media and evidence of germ cell differentiation. Hum Reprod 2007;22:567-577.
    • (2007) Hum Reprod , vol.22 , pp. 567-577
    • Chen, H.F.1    Kuo, H.C.2    Chien, C.L.3
  • 82
    • 33646065973 scopus 로고    scopus 로고
    • Gap junctions modulate apoptosis and colony growth of human embryonic stem cells maintained in a serum-free system
    • Wong RC, Dottori M, Koh KL et al. Gap junctions modulate apoptosis and colony growth of human embryonic stem cells maintained in a serum-free system. Biochem Biophys Res Commun 2006;344:181-188.
    • (2006) Biochem Biophys Res Commun , vol.344 , pp. 181-188
    • Wong, R.C.1    Dottori, M.2    Koh, K.L.3
  • 83
    • 33845598269 scopus 로고    scopus 로고
    • Optimization of serum free medium for cord blood mesenchymal stem cells
    • Liu CH, Wu ML, Hwang SM. Optimization of serum free medium for cord blood mesenchymal stem cells. Biochem Eng J 2007;33:1-9.
    • (2007) Biochem Eng J , vol.33 , pp. 1-9
    • Liu, C.H.1    Wu, M.L.2    Hwang, S.M.3
  • 84
    • 1442308105 scopus 로고    scopus 로고
    • Serum deprivation of human marrow stromal cells (hMSCs) selects for a subpopulation of early progenitor cells with enhanced expression of OCT-4 and other embryonic genes
    • Pochampally RR, Smith JR, Ylostalo J et al. Serum deprivation of human marrow stromal cells (hMSCs) selects for a subpopulation of early progenitor cells with enhanced expression of OCT-4 and other embryonic genes. Blood 2004;103:1647-1652.
    • (2004) Blood , vol.103 , pp. 1647-1652
    • Pochampally, R.R.1    Smith, J.R.2    Ylostalo, J.3
  • 85
    • 0028966028 scopus 로고
    • The growth factor requirements of STRO-1-positive human bone marrow stromal precursors under serum-deprived conditions in vitro
    • Gronthos S, Simmons PJ. The growth factor requirements of STRO-1-positive human bone marrow stromal precursors under serum-deprived conditions in vitro. Blood 1995;85:929-940.
    • (1995) Blood , vol.85 , pp. 929-940
    • Gronthos, S.1    Simmons, P.J.2
  • 86
    • 0030938134 scopus 로고    scopus 로고
    • Factors required for bone marrow stromal fibroblast colony formation in vitro
    • Kuznetsov SA, Friedenstein AJ, Robey PG. Factors required for bone marrow stromal fibroblast colony formation in vitro. Br J Haematol 1997;97:561-570.
    • (1997) Br J Haematol , vol.97 , pp. 561-570
    • Kuznetsov, S.A.1    Friedenstein, A.J.2    Robey, P.G.3
  • 87
    • 31944448899 scopus 로고    scopus 로고
    • Characterisation of serum-induced intracellular Ca2+ oscillations in primary bone marrow stromal cells
    • Foreman MA, Smith J, Publicover SJ. Characterisation of serum-induced intracellular Ca2+ oscillations in primary bone marrow stromal cells. J Cell Physiol 2006;206:664-671.
    • (2006) J Cell Physiol , vol.206 , pp. 664-671
    • Foreman, M.A.1    Smith, J.2    Publicover, S.J.3
  • 88
    • 33745954928 scopus 로고    scopus 로고
    • Hypoxia and serum deprivation-induced apoptosis in mesenchymal stem cells
    • Zhu W, Chen J, Cong X et al. Hypoxia and serum deprivation-induced apoptosis in mesenchymal stem cells. STEM CELLS 2006;24:416-425.
    • (2006) STEM CELLS , vol.24 , pp. 416-425
    • Zhu, W.1    Chen, J.2    Cong, X.3
  • 89
    • 33750592790 scopus 로고    scopus 로고
    • Concise review: Recent advances on the significance of stem cells in tissue regeneration and cancer therapies
    • Mimeault M, Batra SK. Concise review: Recent advances on the significance of stem cells in tissue regeneration and cancer therapies. STEM CELLS 2006;24:2319-2345.
    • (2006) STEM CELLS , vol.24 , pp. 2319-2345
    • Mimeault, M.1    Batra, S.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.