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Volumn 56, Issue 3, 2012, Pages 1004-1014

Nanog regulates self-renewal of cancer stem cells through the insulin-like growth factor pathway in human hepatocellular carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; SOMATOMEDIN B; SOMATOMEDIN C RECEPTOR; SORAFENIB; TRANSCRIPTION FACTOR NANOG;

EID: 84865555780     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.25745     Document Type: Article
Times cited : (262)

References (37)
  • 1
    • 69449096005 scopus 로고    scopus 로고
    • Heterogeneity in cancer: cancer stem cells versus clonal evolution
    • Shackleton M, Quintana E, Fearon ER, Morrison SJ. Heterogeneity in cancer: cancer stem cells versus clonal evolution. Cell 2009; 138: 822-829.
    • (2009) Cell , vol.138 , pp. 822-829
    • Shackleton, M.1    Quintana, E.2    Fearon, E.R.3    Morrison, S.J.4
  • 2
    • 67649939163 scopus 로고    scopus 로고
    • The increasing complexity of the cancer stem cell paradigm
    • Rosen JM, Jordan CT. The increasing complexity of the cancer stem cell paradigm. Science 2009; 324: 1670-1673.
    • (2009) Science , vol.324 , pp. 1670-1673
    • Rosen, J.M.1    Jordan, C.T.2
  • 3
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
    • Visvader JE, Lindeman GJ. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 2008; 8: 755-768.
    • (2008) Nat Rev Cancer , vol.8 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 4
    • 77956178360 scopus 로고    scopus 로고
    • EMT, cancer stem cells, and drug resistance: an emerging axis of evil in the war on cancer
    • Singh A, Settleman J. EMT, cancer stem cells, and drug resistance: an emerging axis of evil in the war on cancer. Oncogene 2010; 29: 4741-4751.
    • (2010) Oncogene , vol.29 , pp. 4741-4751
    • Singh, A.1    Settleman, J.2
  • 5
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
    • Polyak K, Weinberg RA. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 2009; 9: 265-273.
    • (2009) Nat Rev Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 7
    • 78649681554 scopus 로고    scopus 로고
    • miR-130b Promotes CD133(+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1
    • Ma S, Tang KH, Chan YP, Lee TK, Kwan PS, Castilho A, et al. miR-130b Promotes CD133(+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1. Cell Stem Cell 2010; 7: 694-707.
    • (2010) Cell Stem Cell , vol.7 , pp. 694-707
    • Ma, S.1    Tang, K.H.2    Chan, Y.P.3    Lee, T.K.4    Kwan, P.S.5    Castilho, A.6
  • 8
    • 60449087921 scopus 로고    scopus 로고
    • EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features
    • Yamashita T, Ji J, Budhu A, Forgues M, Yang W, Wang HY, et al. EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features. Gastroenterology 2009; 136: 1012-1024.
    • (2009) Gastroenterology , vol.136 , pp. 1012-1024
    • Yamashita, T.1    Ji, J.2    Budhu, A.3    Forgues, M.4    Yang, W.5    Wang, H.Y.6
  • 9
    • 38549139140 scopus 로고    scopus 로고
    • Significance of CD90+ cancer stem cells in human liver cancer
    • Yang ZF, Ho DW, Ng MN, Lau CK, Yu WC, Ngai P, et al. Significance of CD90+ cancer stem cells in human liver cancer. Cancer Cell 2008; 13: 153-166.
    • (2008) Cancer Cell , vol.13 , pp. 153-166
    • Yang, Z.F.1    Ho, D.W.2    Ng, M.N.3    Lau, C.K.4    Yu, W.C.5    Ngai, P.6
  • 10
    • 77957757417 scopus 로고    scopus 로고
    • A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs
    • Kim J, Woo AJ, Chu J, Snow JW, Fujiwara Y, Kim CG, et al. A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs. Cell 2010; 143: 313-324.
    • (2010) Cell , vol.143 , pp. 313-324
    • Kim, J.1    Woo, A.J.2    Chu, J.3    Snow, J.W.4    Fujiwara, Y.5    Kim, C.G.6
  • 12
    • 48249105531 scopus 로고    scopus 로고
    • Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma
    • Chiou SH, Yu CC, Huang CY, Lin SC, Liu CJ, Tsai TH, et al. Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma. Clin Cancer Res 2008; 14: 4085-4095.
    • (2008) Clin Cancer Res , vol.14 , pp. 4085-4095
    • Chiou, S.H.1    Yu, C.C.2    Huang, C.Y.3    Lin, S.C.4    Liu, C.J.5    Tsai, T.H.6
  • 15
    • 58949102947 scopus 로고    scopus 로고
    • Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells
    • Somervaille TC, Matheny CJ, Spencer GJ, Iwasaki M, Rinn JL, Witten DM, et al. Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells. Cell Stem Cell 2009; 4: 129-140.
    • (2009) Cell Stem Cell , vol.4 , pp. 129-140
    • Somervaille, T.C.1    Matheny, C.J.2    Spencer, G.J.3    Iwasaki, M.4    Rinn, J.L.5    Witten, D.M.6
  • 16
    • 79952119592 scopus 로고    scopus 로고
    • A CD133-related gene expression signature identifies an aggressive glioblastoma subtype with excessive mutations
    • Yan X, Ma L, Yi D, Yoon JG, Diercks A, Foltz G, et al. A CD133-related gene expression signature identifies an aggressive glioblastoma subtype with excessive mutations. Proc Natl Acad Sci U S A 2011; 108: 1591-1596.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 1591-1596
    • Yan, X.1    Ma, L.2    Yi, D.3    Yoon, J.G.4    Diercks, A.5    Foltz, G.6
  • 17
    • 83555162579 scopus 로고    scopus 로고
    • Molecular diagnosis and therapy of hepatocellular carcinoma (HCC): an emerging field for advanced technologies
    • Marquardt JU, Galle PR, Teufel A. Molecular diagnosis and therapy of hepatocellular carcinoma (HCC): an emerging field for advanced technologies. J Hepatol 2011; 56: 267-275.
    • (2011) J Hepatol , vol.56 , pp. 267-275
    • Marquardt, J.U.1    Galle, P.R.2    Teufel, A.3
  • 18
    • 77953553879 scopus 로고    scopus 로고
    • Overexpression of nanog predicts tumor progression and poor prognosis in colorectal cancer
    • Meng HM, Zheng P, Wang XY, Liu C, Sui HM, Wu SJ, et al. Overexpression of nanog predicts tumor progression and poor prognosis in colorectal cancer. Cancer Biol Ther 2010; 9: 295-302.
    • (2010) Cancer Biol Ther , vol.9 , pp. 295-302
    • Meng, H.M.1    Zheng, P.2    Wang, X.Y.3    Liu, C.4    Sui, H.M.5    Wu, S.J.6
  • 19
    • 66149167315 scopus 로고    scopus 로고
    • Functional evidence that the self-renewal gene NANOG regulates human tumor development
    • Jeter CR, Badeaux M, Choy G, Chandra D, Patrawala L, Liu C, et al. Functional evidence that the self-renewal gene NANOG regulates human tumor development. Stem Cells 2009; 27: 993-1005.
    • (2009) Stem Cells , vol.27 , pp. 993-1005
    • Jeter, C.R.1    Badeaux, M.2    Choy, G.3    Chandra, D.4    Patrawala, L.5    Liu, C.6
  • 21
    • 40649116943 scopus 로고    scopus 로고
    • Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling
    • Tang Y, Kitisin K, Jogunoori W, Li C, Deng CX, Mueller SC, et al. Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling. Proc Natl Acad Sci U S A 2008; 105: 2445-2450.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 2445-2450
    • Tang, Y.1    Kitisin, K.2    Jogunoori, W.3    Li, C.4    Deng, C.X.5    Mueller, S.C.6
  • 22
    • 77952564300 scopus 로고    scopus 로고
    • The identification of stem cells in human liver diseases and hepatocellular carcinoma
    • Oliva J, French BA, Qing X, French SW. The identification of stem cells in human liver diseases and hepatocellular carcinoma. Exp Mol Pathol 2010; 88: 331-340.
    • (2010) Exp Mol Pathol , vol.88 , pp. 331-340
    • Oliva, J.1    French, B.A.2    Qing, X.3    French, S.W.4
  • 23
    • 79960006754 scopus 로고    scopus 로고
    • CD24(+) liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation
    • Lee TK, Castilho A, Cheung VC, Tang KH, Ma S, Ng IO. CD24(+) liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation. Cell Stem Cell 2011; 9: 50-63.
    • (2011) Cell Stem Cell , vol.9 , pp. 50-63
    • Lee, T.K.1    Castilho, A.2    Cheung, V.C.3    Tang, K.H.4    Ma, S.5    Ng, I.O.6
  • 24
    • 62949170893 scopus 로고    scopus 로고
    • Mouse fibroblasts lacking RB1 function form spheres and undergo reprogramming to a cancer stem cell phenotype
    • Liu Y, Clem B, Zuba-Surma EK, El-Naggar S, Telang S, Jenson AB, et al. Mouse fibroblasts lacking RB1 function form spheres and undergo reprogramming to a cancer stem cell phenotype. Cell Stem Cell 2009; 4: 336-347.
    • (2009) Cell Stem Cell , vol.4 , pp. 336-347
    • Liu, Y.1    Clem, B.2    Zuba-Surma, E.K.3    El-Naggar, S.4    Telang, S.5    Jenson, A.B.6
  • 25
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008; 133: 704-715.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3    Eaton, E.N.4    Ayyanan, A.5    Zhou, A.Y.6
  • 26
    • 77955428416 scopus 로고    scopus 로고
    • NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53
    • Zbinden M, Duquet A, Lorente-Trigos A, Ngwabyt SN, Borges I, Ruiz i Altaba A. NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53. EMBO J 2010; 29: 2659-2674.
    • (2010) EMBO J , vol.29 , pp. 2659-2674
    • Zbinden, M.1    Duquet, A.2    Lorente-Trigos, A.3    Ngwabyt, S.N.4    Borges, I.5    Ruiz i Altaba, A.6
  • 27
    • 77950503213 scopus 로고    scopus 로고
    • Expression of pluripotent stem cell reprogramming factors by prostate tumor initiating cells
    • Bae KM, Su Z, Frye C, McClellan S, Allan RW, Andrejewski JT, et al. Expression of pluripotent stem cell reprogramming factors by prostate tumor initiating cells. J Urol 2010; 183: 2045-2053.
    • (2010) J Urol , vol.183 , pp. 2045-2053
    • Bae, K.M.1    Su, Z.2    Frye, C.3    McClellan, S.4    Allan, R.W.5    Andrejewski, J.T.6
  • 30
    • 33747830764 scopus 로고    scopus 로고
    • Hepatocellular carcinoma pathogenesis: from genes to environment
    • Farazi PA, DePinho RA. Hepatocellular carcinoma pathogenesis: from genes to environment. Nat Rev Cancer 2006; 6: 674-687.
    • (2006) Nat Rev Cancer , vol.6 , pp. 674-687
    • Farazi, P.A.1    DePinho, R.A.2
  • 32
    • 79251492356 scopus 로고    scopus 로고
    • Hedgehog/GLI1 regulates IGF dependent malignant behaviors in glioma stem cells
    • Hsieh A, Ellsworth R, Hsieh D. Hedgehog/GLI1 regulates IGF dependent malignant behaviors in glioma stem cells. J Cell Physiol 2011; 226: 1118-1127.
    • (2011) J Cell Physiol , vol.226 , pp. 1118-1127
    • Hsieh, A.1    Ellsworth, R.2    Hsieh, D.3
  • 33
    • 62449205665 scopus 로고    scopus 로고
    • Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like-like growth factor-I receptor inhibition
    • Dallas NA, Xia L, Fan F, Gray MJ, Gaur P, van Buren G, 2nd, et al. Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like-like growth factor-I receptor inhibition. Cancer Res 2009; 69: 1951-1957.
    • (2009) Cancer Res , vol.69 , pp. 1951-1957
    • Dallas, N.A.1    Xia, L.2    Fan, F.3    Gray, M.J.4    Gaur, P.5    van Buren 2nd, G.6
  • 34
    • 33745552897 scopus 로고    scopus 로고
    • Dysregulation of growth factor signaling in human hepatocellular carcinoma
    • Breuhahn K, Longerich T, Schirmacher P. Dysregulation of growth factor signaling in human hepatocellular carcinoma. Oncogene 2006; 25: 3787-3800.
    • (2006) Oncogene , vol.25 , pp. 3787-3800
    • Breuhahn, K.1    Longerich, T.2    Schirmacher, P.3
  • 35
    • 47149111583 scopus 로고    scopus 로고
    • Autocrine insulin-like-like growth factor-II stimulation of tumor cell migration is a progression step in human hepatocarcinogenesis
    • Nussbaum T, Samarin J, Ehemann V, Bissinger M, Ryschich E, Khamidjanov A, et al. Autocrine insulin-like-like growth factor-II stimulation of tumor cell migration is a progression step in human hepatocarcinogenesis. HEPATOLOGY 2008; 48: 146-156.
    • (2008) HEPATOLOGY , vol.48 , pp. 146-156
    • Nussbaum, T.1    Samarin, J.2    Ehemann, V.3    Bissinger, M.4    Ryschich, E.5    Khamidjanov, A.6
  • 36
    • 34548307176 scopus 로고    scopus 로고
    • IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro
    • Bendall SC, Stewart MH, Menendez P, George D, Vijayaragavan K, Werbowetski-Ogilvie T, et al. IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro. Nature 2007; 448: 1015-1021.
    • (2007) Nature , vol.448 , pp. 1015-1021
    • Bendall, S.C.1    Stewart, M.H.2    Menendez, P.3    George, D.4    Vijayaragavan, K.5    Werbowetski-Ogilvie, T.6
  • 37
    • 78649631618 scopus 로고    scopus 로고
    • A potential role for insulin-like-like growth factor signaling in induction of pluripotent stem cell formation
    • Li Y, Geng YJ. A potential role for insulin-like-like growth factor signaling in induction of pluripotent stem cell formation. Growth Horm IGF Res 2010; 20: 391-398.
    • (2010) Growth Horm IGF Res , vol.20 , pp. 391-398
    • Li, Y.1    Geng, Y.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.