Neuroprotective effects of a novel single compound 1-methoxyoctadecan-1-ol isolated from Uncaria sinensis in primary cortical neurons and a photothrombotic ischemia model

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Jang, Ji Yeon ^a   Choi, Young Whan ^a   Kim, Ha Neui ^a   Kim, Yu Ri ^a   Hong, Jin Woo ^a   Bae, Dong Won ^b   Park, Se Jin ^a   Shin, Hwa Kyoung ^a   Choi, Byung Tae ^a  

^a Pusan National University   (South Korea)

^b Gyeongsang National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHOXYOCTADECAN 1 OL; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CALPAIN; GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE P38; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROPROTECTIVE AGENT; PROTEIN TYROSINE PHOSPHATASE; STRIATAL ENRICHED PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CELL NUCLEUS; CELL STRUCTURE; CENTRAL NERVOUS SYSTEM FUNCTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG MECHANISM; DRUG SCREENING; EDEMA SIZE; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; EXCITOTOXICITY; HYPOXIC ISCHEMIC ENCEPHALOPATHY; MALE; MOUSE; NERVE CELL NECROSIS; NERVOUS SYSTEM PARAMETERS; NEUROPROTECTION; NEUROTOXICITY; NEUROTRANSMISSION; NONHUMAN; PHOTOTHROMBOTIC ISCHEMIA; PLANT STEM; PROTEIN CLEAVAGE; RAT; TREATMENT OUTCOME; UNCARIA; UNCARIA SINENSIS;

ANIMALS; BRAIN ISCHEMIA; CALPAIN; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; FATTY ALCOHOLS; GENE EXPRESSION REGULATION; GLUTAMIC ACID; IMIDAZOLES; MICE; NEURONS; NEUROPROTECTIVE AGENTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOTOCHEMICAL PROCESSES; PRIMARY CELL CULTURE; PROTEIN TYROSINE PHOSPHATASES, NON-RECEPTOR; PYRIDINES; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SIGNAL TRANSDUCTION; THROMBOSIS; UNCARIA;

EID: 84896973807     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085322     Document Type: Article

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