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Volumn 11, Issue 13, 2003, Pages 2751-2759

Design of artificial nucleobases for the recognition of the AT inversion by triple-helix forming oligonucleotides: A structure-stability relationship study and neighbour bases effect

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEIC ACID BASE; OLIGONUCLEOTIDE; PYRIMIDINE;

EID: 0038143610     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(03)00229-3     Document Type: Article
Times cited : (46)

References (46)
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    • The symbols · and x indicate Watson-Crick and Hoogsteen hydrogen bonds, respectively.
  • 14
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    • Reviews:(a) Sun J.S., Hélène C. Cur. Opin. Struct. Biol. 3:1993;345 (b) Doronina S.O., Behr J.P. Chem. Soc. Rev. 1997;63 (c) Gowers D.M., Fox K.R. Nucleic Acids Res. 27:1999;1569. and references cited therein.
    • (1993) Cur. Opin. Struct. Biol. , vol.3 , pp. 345
    • Sun, J.S.1    Hélène, C.2
  • 15
    • 0031536366 scopus 로고    scopus 로고
    • Reviews:(a) Sun J.S., Hélène C. Cur. Opin. Struct. Biol. 3:1993;345 (b) Doronina S.O., Behr J.P. Chem. Soc. Rev. 1997;63 (c) Gowers D.M., Fox K.R. Nucleic Acids Res. 27:1999;1569. and references cited therein.
    • (1997) Chem. Soc. Rev. , pp. 63
    • Doronina, S.O.1    Behr, J.P.2
  • 16
    • 0033118865 scopus 로고    scopus 로고
    • Reviews:(a). and references cited therein
    • Reviews:(a) Sun J.S., Hélène C. Cur. Opin. Struct. Biol. 3:1993;345 (b) Doronina S.O., Behr J.P. Chem. Soc. Rev. 1997;63 (c) Gowers D.M., Fox K.R. Nucleic Acids Res. 27:1999;1569. and references cited therein.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 1569
    • Gowers, D.M.1    Fox, K.R.2
  • 36
    • 85031170965 scopus 로고    scopus 로고
    • Compound 5 was obtained in three steps from 2-aminothiazole (see ref 8b)
    • Compound 5 was obtained in three steps from 2-aminothiazole (see ref 8b).
  • 38
    • 85031172366 scopus 로고    scopus 로고
    • 2O leading to a 1:3 mixture of α/β anomers in 90% yield
    • 2O leading to a 1:3 mixture of α/β anomers in 90% yield.
  • 40
    • 85031167545 scopus 로고    scopus 로고
    • 2 and 0.5 mM spermine.
  • 42
    • 0026000474 scopus 로고
    • (a) NMR structural studies of the A·TxG triplet have explained this stabilization by the existence of a favourable stacking interaction between guanine (of the triplet A·TxG) and the thymine on the 5′-side (Radhakrishnan, I.; Gao, X.; De Los Santos, C.; Live, D.; Patel, D. J. Biochemistry 1991, 30, 9022).
    • (1991) J. Biochemistry , vol.30 , pp. 9022
    • Radhakrishnan, I.1    Gao, X.2    De Los Santos, C.3    Live, D.4    Patel, D.5
  • 43
    • 85031170863 scopus 로고    scopus 로고
    • 2 when Z=S
    • 2 when Z=S.
  • 44
    • 0026000474 scopus 로고
    • (a) NMR structural studies of the A·TxG triplet have explained this stabilization by the existence of a favourable stacking interaction between guanine (of the triplet A·TxG) and the thymine on the 5′-side (Radhakrishnan, I.; Gao, X.; De Los Santos, C.; Live, D.; Patel, D. J. Biochemistry 1991, 30, 9022).
    • (1991) J. Biochemistry , vol.30 , pp. 9022
    • Radhakrishnan, I.1    Gao, X.2    De Los Santos, C.3    Live, D.4    Patel, D.5
  • 45
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    • 2 when Z=S
    • 2 when Z=S.
  • 46
    • 0001594480 scopus 로고    scopus 로고
    • 3 to be intercalated between the A·T inverted base pair and the 3′ neighbouring triplet thus explaining the 3′ neighbour effect (Koshlap, K.M.; Gillespie, P.; Dervan, P.B.; Feigon, J. J. Am. Chem. Soc. 1993, 115, 7908). In the case of S, this absence of 3′ or 5′ effect seems to be in favour of a recognition process which involves hydrogen bond contacts.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.