Aminoglycoside binding to the hammerhead ribozyme: A general model for the interaction of cationic antibiotics with RNA

Journal of Molecular Biology

Volumn 276, Issue 5, 1998, Pages 903-912

  Hermann, Thomas ^a   Westhof, Eric ^a  

^a INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Drug design; Metal ion binding sites; Molecular dynamics simulations; Neomycin

Indexed keywords

AMINOGLYCOSIDE; AMMONIA; ANTIBIOTIC AGENT; FRAMYCETIN; KANAMYCIN; MAGNESIUM ION; RIBOZYME; RNA; TOBRAMYCIN;

ARTICLE; BINDING SITE; COVALENT BOND; CRYSTALLOGRAPHY; DRUG BINDING; DRUG SYNTHESIS; MOLECULAR DYNAMICS; PRIORITY JOURNAL; RNA STRUCTURE; SIMULATION;

EID: 0032513007     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1997.1590     Document Type: Article

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