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Volumn 11, Issue 2, 2014, Pages 207-214

Putative biomarkers and therapeutic targets associated with radiation resistance

Author keywords

biomarker; cancer stem cells; intracellular signaling; proteomics; radiation therapy

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE ISOENZYME 1; BIOLOGICAL MARKER; CA 19-9 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; CHAPERONIN 60; CYCLOPHILIN A; DEOXYRIBONUCLEASE I; GLUCOSE REGULATED PROTEIN 78; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; NUCLEOSIDE DIPHOSPHATE KINASE A; RAC1 PROTEIN; REDOX FACTOR 1 APURINIC APYRIMIDINIC ENDONUCLEASE 1; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; APEX1 PROTEIN, HUMAN; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; HEAT SHOCK PROTEIN; NUCLEOSIDE DIPHOSPHATE KINASE NM23; PROTEOME; RAC1 PROTEIN, HUMAN; TUMOR MARKER;

EID: 84896942587     PISSN: 14789450     EISSN: 17448387     Source Type: Journal    
DOI: 10.1586/14789450.2014.893194     Document Type: Review
Times cited : (14)

References (54)
  • 1
    • 84882736607 scopus 로고    scopus 로고
    • How can Proteomics Reach Cancer Biomarkers?
    • Panis C, Pizzatti L, Abdelhay E. How can Proteomics Reach Cancer Biomarkers? Curr Proteomics 2013;10:136-49
    • (2013) Curr Proteomics , vol.10 , pp. 136-149
    • Panis, C.1    Pizzatti, L.2    Abdelhay, E.3
  • 2
    • 84976905617 scopus 로고    scopus 로고
    • Multi-parameter systematic strategies for predictive, preventive and personalised medicine in cancer
    • Hu R, Wang X, Zhan X. Multi-parameter systematic strategies for predictive, preventive and personalised medicine in cancer. EPMA J 2013;4:2
    • (2013) EPMA J , vol.4 , pp. 2
    • Hu, R.1    Wang, X.2    Zhan, X.3
  • 3
    • 70350716432 scopus 로고    scopus 로고
    • Proteomic identification of putative biomarkers of radiotherapy resistance: A possible role for the 26S proteasome?
    • Smith L, Qutob O, Watson MB, et al. Proteomic identification of putative biomarkers of radiotherapy resistance: a possible role for the 26S proteasome? Neoplasia 2009;11:1194-207
    • (2009) Neoplasia , vol.11 , pp. 1194-1207
    • Smith, L.1    Qutob, O.2    Watson, M.B.3
  • 4
    • 55849153134 scopus 로고    scopus 로고
    • Intracellular signaling pathways regulating radioresistance of human prostate carcinoma cells
    • Skvortsova I, Skvortsov S, Stasyk T, et al. Intracellular signaling pathways regulating radioresistance of human prostate carcinoma cells. Proteomics 2008;8:4521-33
    • (2008) Proteomics , vol.8 , pp. 4521-4533
    • Skvortsova, I.1    Skvortsov, S.2    Stasyk, T.3
  • 5
    • 80655149141 scopus 로고    scopus 로고
    • Radioresistant head and neck squamous cell carcinoma cells: Intracellular signaling, putative biomarkers for tumor recurrences and possible therapeutic targets
    • Skvortsov S, Jimenez CR, Knol JC, et al. Radioresistant head and neck squamous cell carcinoma cells: intracellular signaling, putative biomarkers for tumor recurrences and possible therapeutic targets. Radiother Oncol 2011;101:177-82
    • (2011) Radiother Oncol , vol.101 , pp. 177-182
    • Skvortsov, S.1    Jimenez, C.R.2    Knol, J.C.3
  • 7
    • 79952370202 scopus 로고    scopus 로고
    • The cancer stem cell: Premises, promises and challenges
    • Clevers H. The cancer stem cell: premises, promises and challenges. Nat Med 2011;17: 313-19
    • (2011) Nat Med , vol.17 , pp. 313-319
    • Clevers, H.1
  • 8
    • 84871327738 scopus 로고    scopus 로고
    • Identification of heat shock protein 27 as a radioresistance-related protein in nasopharyngeal carcinoma cells
    • Zhang B, Qu JQ, Xiao L, et al. Identification of heat shock protein 27 as a radioresistance-related protein in nasopharyngeal carcinoma cells. J Cancer Res Clin Oncol 2012;138:2117-25
    • (2012) J Cancer Res Clin Oncol , vol.138 , pp. 2117-2125
    • Zhang, B.1    Qu, J.Q.2    Xiao, L.3
  • 9
    • 77955923224 scopus 로고    scopus 로고
    • Proteomics of the radioresistant phenotype in head-and-neck cancer: Gp96 as a novel prediction marker and sensitizing target for radiotherapy
    • Lin TY, Chang JT, Wang HM, et al. Proteomics of the radioresistant phenotype in head-and-neck cancer: gp96 as a novel prediction marker and sensitizing target for radiotherapy. Int J Radiat Oncol Biol Phys 2010;78:246-56
    • (2010) Int J Radiat Oncol Biol Phys , vol.78 , pp. 246-256
    • Lin, T.Y.1    Chang, J.T.2    Wang, H.M.3
  • 10
    • 33745867614 scopus 로고    scopus 로고
    • Rituximab enhances radiation-triggered apoptosis in non-Hodgkin's lymphoma cells via caspase-dependent and - Independent mechanisms
    • Skvortsova I, Skvortsov S, Popper BA, et al. Rituximab enhances radiation-triggered apoptosis in non-Hodgkin's lymphoma cells via caspase-dependent and - independent mechanisms. J Radiat Res 2006;47:183-96
    • (2006) J Radiat Res , vol.47 , pp. 183-196
    • Skvortsova, I.1    Skvortsov, S.2    Popper, B.A.3
  • 11
    • 77951763152 scopus 로고    scopus 로고
    • Identification of biomarkers for predicting nasopharyngeal carcinoma response to radiotherapy by proteomics
    • Feng XP, Yi H, Li MY, et al. Identification of biomarkers for predicting nasopharyngeal carcinoma response to radiotherapy by proteomics. Cancer Res 2010;70:3450-62
    • (2010) Cancer Res , vol.70 , pp. 3450-3462
    • Feng, X.P.1    Yi, H.2    Li, M.Y.3
  • 12
    • 84860392773 scopus 로고    scopus 로고
    • Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma
    • Svendsen A, Verhoeff JJ, Immervoll H, et al. Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma. Acta Neuropathol 2011;122: 495-510
    • (2011) Acta Neuropathol , vol.122 , pp. 495-510
    • Svendsen, A.1    Verhoeff, J.J.2    Immervoll, H.3
  • 13
    • 84862903426 scopus 로고    scopus 로고
    • Accumulation of cyclophilin A isoforms in conditioned medium of irradiated breast cancer cells
    • Chevalier F, Depagne J, Hem S, et al. Accumulation of cyclophilin A isoforms in conditioned medium of irradiated breast cancer cells. Proteomics 2012;12: 1756-66
    • (2012) Proteomics , vol.12 , pp. 1756-1766
    • Chevalier, F.1    Depagne, J.2    Hem, S.3
  • 14
    • 84863012852 scopus 로고    scopus 로고
    • Identification of ERp29 as a biomarker for predicting nasopharyngeal carcinoma response to radiotherapy
    • Wu P, Zhang H, Qi L, et al. Identification of ERp29 as a biomarker for predicting nasopharyngeal carcinoma response to radiotherapy. Oncol Rep 2012;27:987-94
    • (2012) Oncol Rep , vol.27 , pp. 987-994
    • Wu, P.1    Zhang, H.2    Qi, L.3
  • 15
    • 84872358363 scopus 로고    scopus 로고
    • Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: An update
    • Ciocca DR, Arrigo AP, Calderwood SK. Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update. Arch Toxicol 2013;87:19-48
    • (2013) Arch Toxicol , vol.87 , pp. 19-48
    • Ciocca, D.R.1    Arrigo, A.P.2    Calderwood, S.K.3
  • 16
    • 84867782766 scopus 로고    scopus 로고
    • Role of human and mouse HspB1 in metastasis
    • Nagaraja GM, Kaur P, Asea A. Role of human and mouse HspB1 in metastasis. Curr Mol Med 2012;12:1142-50
    • (2012) Curr Mol Med , vol.12 , pp. 1142-1150
    • Nagaraja, G.M.1    Kaur, P.2    Asea, A.3
  • 17
    • 80054814409 scopus 로고    scopus 로고
    • Hsp27 participates in the maintenance of breast cancer stem cells through regulation of epithelial-mesenchymal transition and nuclear factor-kappaB
    • Wei L, Liu TT, Wang HH, et al. Hsp27 participates in the maintenance of breast cancer stem cells through regulation of epithelial-mesenchymal transition and nuclear factor-kappaB. Breast Cancer Res 2011;13:R101
    • (2011) Breast Cancer Res , vol.13
    • Wei, L.1    Liu, T.T.2    Wang, H.H.3
  • 18
    • 84877864064 scopus 로고    scopus 로고
    • Novel HSP90 inhibitor NVP-HSP990 targets cell-cycle regulators to ablate Olig2-positive glioma tumor-initiating cells
    • Fu J, Koul D, Yao J, et al. Novel HSP90 inhibitor NVP-HSP990 targets cell-cycle regulators to ablate Olig2-positive glioma tumor-initiating cells. Cancer Res 2013;73:3062-74
    • (2013) Cancer Res , vol.73 , pp. 3062-3074
    • Fu, J.1    Koul, D.2    Yao, J.3
  • 19
    • 84862772908 scopus 로고    scopus 로고
    • Cripto/ GRP78 modulation of the TGF-beta pathway in development and oncogenesis
    • Gray PC, Vale W. Cripto/ GRP78 modulation of the TGF-beta pathway in development and oncogenesis. FEBS Lett 2012;586:1836-45
    • (2012) FEBS Lett , vol.586 , pp. 1836-1845
    • Gray, P.C.1    Vale, W.2
  • 20
    • 77958467209 scopus 로고    scopus 로고
    • Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling
    • Wu MJ, Jan CI, Tsay YG, et al. Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling. Mol Cancer 2010;9:283
    • (2010) Mol Cancer , vol.9 , pp. 283
    • Wu, M.J.1    Jan, C.I.2    Tsay, Y.G.3
  • 21
    • 82755186062 scopus 로고    scopus 로고
    • Identification and verification of heat shock protein 60 as a potential serum marker for colorectal cancer
    • Hamelin C, Cornut E, Poirier F, et al. Identification and verification of heat shock protein 60 as a potential serum marker for colorectal cancer. FEBS J 2011;278:4845-59
    • (2011) FEBS J , vol.278 , pp. 4845-4859
    • Hamelin, C.1    Cornut, E.2    Poirier, F.3
  • 22
    • 83455164922 scopus 로고    scopus 로고
    • Heat shock proteins 27 and 70 are potential biliary markers for the detection of cholangiocarcinoma
    • Sato Y, Harada K, Sasaki M, et al. Heat shock proteins 27 and 70 are potential biliary markers for the detection of cholangiocarcinoma. Am J Pathol 2012;180: 123-30
    • (2012) Am J Pathol , vol.180 , pp. 123-130
    • Sato, Y.1    Harada, K.2    Sasaki, M.3
  • 23
    • 78649874180 scopus 로고    scopus 로고
    • GRP78 as potential predictor for breast cancer response to adjuvant taxane therapy
    • Lee E, Nichols P, Groshen S, et al. GRP78 as potential predictor for breast cancer response to adjuvant taxane therapy. Int J Cancer 2011;128:726-31
    • (2011) Int J Cancer , vol.128 , pp. 726-731
    • Lee, E.1    Nichols, P.2    Groshen, S.3
  • 24
    • 84875902088 scopus 로고    scopus 로고
    • Redox homeostasis: The linchpin in stem cell self-renewal and differentiation
    • Wang K, Zhang T, Dong Q, et al. Redox homeostasis: the linchpin in stem cell self-renewal and differentiation. Cell Death Dis 2013;4:e537
    • (2013) Cell Death Dis , vol.4
    • Wang, K.1    Zhang, T.2    Dong, Q.3
  • 25
    • 84881243404 scopus 로고    scopus 로고
    • Colon cancer progression is driven by APEX1-mediated upregulation of Jagged
    • Kim MH, Kim HB, Yoon SP, et al. Colon cancer progression is driven by APEX1-mediated upregulation of Jagged. J Clin Invest 2013;123(8):3211-30
    • (2013) J Clin Invest , vol.123 , Issue.8 , pp. 3211-3230
    • Kim, M.H.1    Kim, H.B.2    Yoon, S.P.3
  • 26
    • 19344368932 scopus 로고    scopus 로고
    • Topoisomerase IIalpha and APE/ref-1 are associated with pathologic response to primary anthracycline-based chemotherapy for breast cancer
    • Minisini AM, Di LC, Mansutti M, et al. Topoisomerase IIalpha and APE/ref-1 are associated with pathologic response to primary anthracycline-based chemotherapy for breast cancer. Cancer Lett 2005;224: 133-9
    • (2005) Cancer Lett , vol.224 , pp. 133-139
    • Minisini, A.M.1    Di Mansutti, L.C.M.2
  • 28
    • 3543149047 scopus 로고    scopus 로고
    • Nucleoside diphosphate kinase A/nm23-H1 promotes metastasis of NB69-derived human neuroblastoma
    • Almgren MA, Henriksson KC, Fujimoto J, Chang CL. Nucleoside diphosphate kinase A/nm23-H1 promotes metastasis of NB69-derived human neuroblastoma. Mol Cancer Res 2004;2:387-94
    • (2004) Mol Cancer Res , vol.2 , pp. 387-394
    • Almgren, M.A.1    Henriksson, K.C.2    Fujimoto, J.3    Chang, C.L.4
  • 29
    • 79955447372 scopus 로고    scopus 로고
    • Nuclear localization of Nm23-H1 in head and neck squamous cell carcinoma is associated with radiation resistance
    • Kim SH, Lee SY, Park HR, et al. Nuclear localization of Nm23-H1 in head and neck squamous cell carcinoma is associated with radiation resistance. Cancer 2011;117: 1864-73
    • (2011) Cancer , vol.117 , pp. 1864-1873
    • Kim, S.H.1    Lee, S.Y.2    Park, H.R.3
  • 30
    • 79960364956 scopus 로고    scopus 로고
    • The small GTPase Rac1 is involved in the maintenance of stemness and malignancies in glioma stem-like cells
    • Yoon CH, Hyun KH, Kim RK, et al. The small GTPase Rac1 is involved in the maintenance of stemness and malignancies in glioma stem-like cells. FEBS Lett 2011;585:2331-8
    • (2011) FEBS Lett , vol.585 , pp. 2331-2338
    • Yoon, C.H.1    Hyun, K.H.2    Kim, R.K.3
  • 31
    • 79952187822 scopus 로고    scopus 로고
    • Activation of H-Ras and Rac1 correlates with epidermal growth factor-induced invasion in Hs578T and MDA-MB-231 breast carcinoma cells
    • Koh MS, Moon A. Activation of H-Ras and Rac1 correlates with epidermal growth factor-induced invasion in Hs578T and MDA-MB-231 breast carcinoma cells. Biochem Biophys Res Commun 2011;406: 25-9
    • (2011) Biochem Biophys Res Commun , vol.406 , pp. 25-29
    • Koh, M.S.1    Moon, A.2
  • 32
    • 66649121354 scopus 로고    scopus 로고
    • Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma
    • Ma Q, Cavallin LE, Yan B, et al. Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma. Proc Natl Acad Sci USA 2009;106:8683-8
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 8683-8688
    • Ma, Q.1    Cavallin, L.E.2    Yan, B.3
  • 33
    • 40849083771 scopus 로고    scopus 로고
    • Aldosterone induces superoxide generation via Rac1 activation in endothelial cells
    • Iwashima F, Yoshimoto T, Minami I, et al. Aldosterone induces superoxide generation via Rac1 activation in endothelial cells. Endocrinology 2008;149:1009-14
    • (2008) Endocrinology , vol.149 , pp. 1009-1014
    • Iwashima, F.1    Yoshimoto, T.2    Minami, I.3
  • 34
    • 84862155618 scopus 로고    scopus 로고
    • The role of Rac1 in the regulation of NF-kappaB activity, cell proliferation, and cell migration in non-small cell lung carcinoma
    • Gastonguay A, Berg T, Hauser AD, et al. The role of Rac1 in the regulation of NF-kappaB activity, cell proliferation, and cell migration in non-small cell lung carcinoma. Cancer Biol Ther 2012;13: 647-56
    • (2012) Cancer Biol Ther , vol.13 , pp. 647-656
    • Gastonguay, A.1    Berg, T.2    Hauser, A.D.3
  • 35
    • 79951798738 scopus 로고    scopus 로고
    • Rac1 targeting suppresses human non-small cell lung adenocarcinoma cancer stem cell activity
    • Akunuru S, Palumbo J, Zhai QJ, Zheng Y. Rac1 targeting suppresses human non-small cell lung adenocarcinoma cancer stem cell activity. PLoS One 2011;6:e16951
    • (2011) PLoS One , vol.6
    • Akunuru, S.1    Palumbo, J.2    Zhai, Q.J.3    Zheng, Y.4
  • 36
    • 33751170901 scopus 로고    scopus 로고
    • Overexpression of RhoA is associated with poor prognosis in hepatocellular carcinoma
    • Li XR, Ji F, Ouyang J, et al. Overexpression of RhoA is associated with poor prognosis in hepatocellular carcinoma. Eur J Surg Oncol 2006;32:1130-4
    • (2006) Eur J Surg Oncol , vol.32 , pp. 1130-1134
    • Li, X.R.1    Ji, F.2    Ouyang, J.3
  • 37
    • 9944251987 scopus 로고    scopus 로고
    • Rho GTPases in human cancer: An unresolved link to upstream and downstream transcriptional regulation
    • Benitah SA, Valeron PF, van Aelst L, et al. Rho GTPases in human cancer: an unresolved link to upstream and downstream transcriptional regulation. Biochim Biophys Acta 2004;1705:121-32
    • (2004) Biochim Biophys Acta , vol.1705 , pp. 121-132
    • Benitah, S.A.1    Valeron, P.F.2    Van Aelst, L.3
  • 38
    • 84858720730 scopus 로고    scopus 로고
    • Nuclear expression of Rac1 in cervical premalignant lesions and cervical cancer cells
    • Mendoza-Catalan MA, Cristobal-Mondragon GR, me-Gomez J, et al. Nuclear expression of Rac1 in cervical premalignant lesions and cervical cancer cells. BMC Cancer 2012;12:116
    • (2012) BMC Cancer , vol.12 , pp. 116
    • Mendoza-Catalan, M.A.1    Cristobal-Mondragon, G.R.2    Me-Gomez, J.3
  • 39
    • 67649386478 scopus 로고    scopus 로고
    • Rac1 contributes to trastuzumab resistance of breast cancer cells: Rac1 as a potential therapeutic target for the treatment of trastuzumab-resistant breast cancer
    • Dokmanovic M, Hirsch DS, Shen Y, Wu WJ. Rac1 contributes to trastuzumab resistance of breast cancer cells: rac1 as a potential therapeutic target for the treatment of trastuzumab-resistant breast cancer. Mol Cancer Ther 2009;8:1557-69
    • (2009) Mol Cancer Ther , vol.8 , pp. 1557-1569
    • Dokmanovic, M.1    Hirsch, D.S.2    Shen, Y.3    Wu, W.J.4
  • 40
    • 84884381617 scopus 로고    scopus 로고
    • Proteomic signatures of acquired letrozole resistance in breast cancer: Suppressed estrogen signaling and increased cell motility and invasiveness
    • Tilghman SL, Townley I, Zhong Q, et al. Proteomic signatures of acquired letrozole resistance in breast cancer: suppressed estrogen signaling and increased cell motility and invasiveness. Mol Cell Proteomics 2013;12(9):2440-55
    • (2013) Mol Cell Proteomics , vol.12 , Issue.9 , pp. 2440-2455
    • Tilghman, S.L.1    Townley, I.2    Zhong, Q.3
  • 41
    • 0037042226 scopus 로고    scopus 로고
    • Rac1 prevents cisplatin-induced apoptosis through down-regulation of p38 activation in NIH3T3 cells
    • Jeong HG, Cho HJ, Chang IY, et al. Rac1 prevents cisplatin-induced apoptosis through down-regulation of p38 activation in NIH3T3 cells. FEBS Lett 2002;518: 129-34
    • (2002) FEBS Lett , vol.518 , pp. 129-134
    • Jeong, H.G.1    Cho, H.J.2    Chang, I.Y.3
  • 42
    • 84883552929 scopus 로고    scopus 로고
    • CCR1 CCL5 interaction promotes invasion of taxane-resistant PC3 prostate cancer cells by increasing secretion of MMPs 29 and by activating ERK and Rac signaling
    • Kato T, Fujita Y, Nakane K, et al. CCR1/ CCL5 interaction promotes invasion of taxane-resistant PC3 prostate cancer cells by increasing secretion of MMPs 2/9 and by activating ERK and Rac signaling. Cytokine 2013;64(1):251-7
    • (2013) Cytokine , vol.64 , Issue.1 , pp. 251-257
    • Kato, T.1    Fujita, Y.2    Nakane, K.3
  • 43
    • 84869053223 scopus 로고    scopus 로고
    • Quercetin suppresses drug-resistant spheres via the p38 MAPK-Hsp27 apoptotic pathway in oral cancer cells
    • Chen SF, Nieh S, Jao SW, et al. Quercetin suppresses drug-resistant spheres via the p38 MAPK-Hsp27 apoptotic pathway in oral cancer cells. PLoS One 2012;7:e49275
    • (2012) PLoS One , vol.7
    • Chen, S.F.1    Nieh, S.2    Jao, S.W.3
  • 44
    • 84875209931 scopus 로고    scopus 로고
    • Heat shock proteins 27, 40, and 70 as combinational and dual therapeutic cancer targets
    • McConnell JR, McAlpine SR. Heat shock proteins 27, 40, and 70 as combinational and dual therapeutic cancer targets. Bioorg Med Chem Lett 2013;23:1923-8
    • (2013) Bioorg Med Chem Lett , vol.23 , pp. 1923-1928
    • McConnell, J.R.1    McAlpine, S.R.2
  • 45
    • 84876420606 scopus 로고    scopus 로고
    • The promise of heat shock protein inhibitors in the treatment of castration resistant prostate cancer
    • Ischia J, Saad F, Gleave M. The promise of heat shock protein inhibitors in the treatment of castration resistant prostate cancer. Curr Opin Urol 2013;23:194-200
    • (2013) Curr Opin Urol , vol.23 , pp. 194-200
    • Ischia, J.1    Saad, F.2    Gleave, M.3
  • 46
    • 84863062001 scopus 로고    scopus 로고
    • Radiosensitization of normoxic and hypoxic h1339 lung tumor cells by heat shock protein 90 inhibition is independent of hypoxia inducible factor-1alpha
    • Schilling D, Bayer C, Li W, et al. Radiosensitization of normoxic and hypoxic h1339 lung tumor cells by heat shock protein 90 inhibition is independent of hypoxia inducible factor-1alpha. PLoS One 2012;7:e31110
    • (2012) PLoS One , vol.7
    • Schilling, D.1    Bayer, C.2    Li, W.3
  • 47
    • 84872107486 scopus 로고    scopus 로고
    • Synergistic effect of heat shock protein inhibitor, 17-allylamino-17- demethoxygeldanamycin and X-rays, but not carbon-ion beams, on lethality in human oral squamous cell carcinoma cells
    • Musha A, Yoshida Y, Takahashi T, et al. Synergistic effect of heat shock protein inhibitor, 17-allylamino-17- demethoxygeldanamycin and X-rays, but not carbon-ion beams, on lethality in human oral squamous cell carcinoma cells. J Radiat Res 2012;53:545-50
    • (2012) J Radiat Res , vol.53 , pp. 545-550
    • Musha, A.1    Yoshida, Y.2    Takahashi, T.3
  • 48
    • 84860254452 scopus 로고    scopus 로고
    • Hsp90 inhibitor NVP-AUY922 enhances radiation sensitivity of tumor cell lines under hypoxia
    • Djuzenova CS, Blassl C, Roloff K, et al. Hsp90 inhibitor NVP-AUY922 enhances radiation sensitivity of tumor cell lines under hypoxia. Cancer Biol Ther 2012;13: 425-34
    • (2012) Cancer Biol Ther , vol.13 , pp. 425-434
    • Djuzenova, C.S.1    Blassl, C.2    Roloff, K.3
  • 49
    • 84855457952 scopus 로고    scopus 로고
    • Hsp90 molecular chaperone inhibitors: Are we there yet?
    • Neckers L, Workman P. Hsp90 molecular chaperone inhibitors: are we there yet? Clin Cancer Res 2012;18:64-76
    • (2012) Clin Cancer Res , vol.18 , pp. 64-76
    • Neckers, L.1    Workman, P.2
  • 50
    • 79952833556 scopus 로고    scopus 로고
    • Functional analysis of novel analogues of E3330 that block the redox signaling activity of the multifunctional AP endonuclease/redox signaling enzyme APE1/ Ref-1
    • Kelley MR, Luo M, Reed A, et al. Functional analysis of novel analogues of E3330 that block the redox signaling activity of the multifunctional AP endonuclease/redox signaling enzyme APE1/ Ref-1. Antioxid Redox Signal 2011;14: 1387-401
    • (2011) Antioxid Redox Signal , vol.14 , pp. 1387-1401
    • Kelley, M.R.1    Luo, M.2    Reed, A.3
  • 51
    • 80052815727 scopus 로고    scopus 로고
    • Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth
    • Fishel ML, Jiang Y, Rajeshkumar NV, et al. Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth. Mol Cancer Ther 2011;10:1698-708
    • (2011) Mol Cancer Ther , vol.10 , pp. 1698-1708
    • Fishel, M.L.1    Jiang, Y.2    Rajeshkumar, N.V.3
  • 53
    • 84868019264 scopus 로고    scopus 로고
    • Targeting of Rac GTPases blocks the spread of intact human breast cancer
    • Katz E, Sims AH, Sproul D, et al. Targeting of Rac GTPases blocks the spread of intact human breast cancer. Oncotarget 2012;3:608-19
    • (2012) Oncotarget , vol.3 , pp. 608-619
    • Katz, E.1    Sims, A.H.2    Sproul, D.3
  • 54
    • 84873106278 scopus 로고    scopus 로고
    • Role of Rac1-mineralocorticoid-receptor signalling in renal and cardiac disease
    • Nagase M, Fujita T. Role of Rac1-mineralocorticoid-receptor signalling in renal and cardiac disease. Nat Rev Nephrol 2013;9:86-98
    • (2013) Nat Rev Nephrol , vol.9 , pp. 86-98
    • Nagase, M.1    Fujita, T.2


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