Proteomic identification of putative biomarkers of radiotherapy resistance: A possible role for the 26S proteasome?

Neoplasia

Volumn 11, Issue 11, 2009, Pages 1194-1207

  Smith, Laura ^a,e   Qutob, Omar ^a   Watson, Mark B ^a   Beavis, Andrew W ^a,b   Potts, Donna ^c   Welham, Kevin J ^a   Garimella, Veerabhadram ^a   Lind, Michael J ^a,b,d   Drew, Philip J ^a,d   Cawkwell, Lynn ^a,d  

^a UNIVERSITY OF HULL   (United Kingdom)

^b CASTLE HILL HOSPITAL   (United Kingdom)

^c Applied Biosystems   (United Kingdom)

^d UNIVERSITY OF HULL   (United Kingdom)

^e ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; PROTEASOME;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER RADIOTHERAPY; CELL STRAIN MCF 7; CELL STRAIN MDA MB 231; CELL STRAIN T47D; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEOMICS; RADIOSENSITIVITY; REAL TIME POLYMERASE CHAIN REACTION; TANDEM MASS SPECTROMETRY; TREATMENT RESPONSE; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING;

EID: 70350716432     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.09902     Document Type: Article

References (33)

1. Nix P, Cawkwell L, Patmore H, Greenman J, and Stafford N (2005). Bcl-2 expression predicts radiotherapy failure in laryngeal cancer. Br J Cancer 92, 2185-2189. (Pubitemid 40966255)
2. Gupta AK, McKenna WG, Weber CN, Feldman MD, Goldsmith JD, Mick R, Machtay M, Rosenthal DI, Bakanauskas VJ, Cerniglia GJ, et al. (2002). Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction. Clin Cancer Res 8, 885-892. (Pubitemid 34742122)
3. Ma BB, Bristow RG, Kim J, and Siu LL (2003). Combined-modality treatment of solid tumors using radiotherapy and molecular targeted agents. J Clin Oncol 21, 2760-2776. (Pubitemid 46613486)
4. McKennaWG, Muschel RJ, Gupta AK, Hahn SM, and Bernhard EJ (2003). The RAS signal transduction pathway and its role in radiation sensitivity. Oncogene 22, 5866-5875. (Pubitemid 37176707)
5. Bussink J, van der Kogel AJ, and Kaanders JH (2008). Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer. Lancet Oncol 9, 288-296. (Pubitemid 351722948)
6. An J, Chervin AS, Nie A, Ducoff HS, and Huang Z (2007). Overcoming the radioresistance of prostate cancer cells with a novel Bcl-2 inhibitor. Oncogene 26, 652-661. (Pubitemid 46204245)
7. Blumenthal RD (2005). Chemosensitivity. Totowa, NJ: Humana Press.
8. Smith L, Welham KJ, Watson MB, Drew PJ, Lind MJ, and Cawkwell L (2007). The proteomic analysis of cisplatin resistance in breast cancer cells. Oncol Res 16, 497-506. (Pubitemid 351211322)
9. Watson MB, Lind MJ, Smith L, Drew PJ, and Cawkwell L (2007). Expression microarray analysis reveals genes associated with in vitro resistance to cisplatin in a cell line model. Acta Oncol 46, 651-658. (Pubitemid 46911906)
10. Schena M, Shalon D, Heller R, Chai A, Brown PO, and Davis RW (1996). Parallel human genome analysis: microarray-based expression monitoring of 1000 genes. Proc Natl Acad Sci USA 93, 10614-10619. (Pubitemid 26333036)
11. Pfaffl MW (2001). A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29, e45.
12. Cawkwell L, Gray S, Murgatroyd H, Sutherland F, Haine L, Longfellow M, O'Loughlin S, Cross D, Kronborg O, Fenger C, et al. (1999). Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair. Gut 45, 409-415. (Pubitemid 29400719)
13. Kyndi M, Sørensen FB, Knudsen H, Overgaard M, Nielsen HM, Overgaard J, and Danish Breast Cancer Cooperative Group (2008). Estrogen receptor, progesterone receptor, HER-2, and response to postmastectomy radiotherapy in highrisk breast cancer: the Danish Breast Cancer Cooperative Group. J Clin Oncol 26, 1419-1426.
14. Nguyen PL, Taghian AG, Katz MS, Niemierko A, Abi Raad RF, Boon WL, Bellon JR, Wong JS, Smith BL, and Harris JR (2008). Breast cancer subtype approximated by estrogen receptor, progesterone receptor, and HER-2 is associated with local and distant recurrence after breast-conserving therapy. J Clin Oncol 26, 2373-2378.
15. Thompson A, Brennan K, Cox A, Gee J, Harcourt D, Harris A, Harvie M, Holen I, Howell A, Nicholson R, et al. (2008). Evaluation of the current knowledge limitations in breast cancer research: a gap analysis. Br Cancer Res 10, R26.
16. Wang T, Tamae D, LeBon T, Shively JE, Yen Y, and Li JJ (2005). The role of peroxiredoxin II in radiation-resistant MCF-7 breast cancer cells. Cancer Res 65, 10338-10346. (Pubitemid 41748145)
17. Zhang L, Wang S, Wangtao, Wang Y, Wang J, Jiang L, Li S, Hu X, and Wang Q (2009). Upregulation of GRP78 and GRP94 and its function in chemotherapy resistance to VP-16 in human lung cancer cell line SK-MES-1. Cancer Invest 27, 453-458.
18. Pyrko P, Schönthal AH, Hofman FM, Chen TC, and Lee AS (2007). The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas. Cancer Res 67, 9809-9816. (Pubitemid 47621228)
19. Lee E, Nichols P, Spicer D, Groshen S, Yu MC, and Lee AS (2006). GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer. Cancer Res 66, 7849-7853. (Pubitemid 44299145)
20. Voges D, Zwickl P, and Baumeister W(1999). The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu Rev Biochem 68, 1015-1068. (Pubitemid 29449214)
21. Zhong Q, Gao W, Du F, and Wang X (2005). Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis. Cell 121, 1085-1095. (Pubitemid 40884398)
22. Kucharczak JF, Simmons MJ, Duckett CS, and Gelinas C (2005). Constitutive proteasome-mediated turnover of Bfl-1/A1 and its processing in response to TNF receptor activation in FL512 pro-B cells convert it into a prodeath factor. Cell Death Differ 12, 1225-1239.
23. Lum JJ, DeBerardinis RJ, and Thompson CB (2005). Autophagy in metazoans: cell survival in the land of plenty. Nat Rev Mol Cell Biol 6, 439-448. (Pubitemid 40780556)
24. Ding WX, Ni HM, Gao W, Yoshimori T, Stolz DB, Ron D, and Yin XM (2007). Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am J Pathol 171, 513-524. (Pubitemid 47344684)
25. Degenhardt K, Mathew R, Beaudoin B, Bray K, Anderson D, Chen G, Mukherjee C, Shi Y, Gelinas C, Fan Y, et al. (2006). Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 10, 51-64.
26. Boya P, Gonzalez-Polo RA, Casares N, Perfettini JL, Dessen P, Larochette N, Metivier D, Meley D, Souquere S, Yoshimori T, et al. (2005). Inhibition of macroautophagy triggers apoptosis. Mol Cell Biol 25, 1025-1040.
27. Apel A, Herr I, Schwarz H, Rodemann HP, and Mayer A (2008).Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy. Cancer Res 68, 1485-1494.
28. Gudmundsdottir K, Lord CJ, and Ashworth A (2007). The proteasome is involved in determining differential utilization of double-strand break repair pathways. Oncogene 26, 7601-7606. (Pubitemid 350207715)
29. Krogan NJ, Lam MH, Fillingham J, Keogh MC, Gebbia M, Li J, Datta N, Cagney G, Buratowski S, Emili A, et al. (2004). Proteasome involvement in the repair of DNA double-strand breaks. Mol Cell 16, 1027-1034. (Pubitemid 40018411)
30. Motegi A, Murakawa Y, and Takeda S (2009). The vital link between the ubiquitin-proteasome pathway and DNA repair: impact on cancer therapy. Cancer Lett 283, 1-9.
31. Smith L, Lind MJ, Drew PJ, and Cawkwell L (2007). The putative roles of the ubiquitin/proteasome pathway in resistance to anticancer therapy. Eur J Cancer 43, 2330-2338. (Pubitemid 47625968)
32. Vlashi E, Kim K, Lagadec C, Donna LD, McDonald JT, Eghbali M, Sayre JW, Stefani E, McBride W, and Pajonk F (2009). In vivo imaging, tracking, and targeting of cancer stem cells. J Natl Cancer Inst 101, 350-359.
33. Maksymowych WP, Ikawa T, Yamaguchi A, Ikeda M, McDonald D, Laouar L, Lahesmaa R, Tamura N, Khuong A, Yu DT, et al. (1998). Invasion by Salmonella typhimurium induces increased expression of the LMP, MECL, and PA28 proteasome genes and changes in the peptide repertoire of HLA-B27. Infect Immun 66, 4624-4632. (Pubitemid 28453061)