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Volumn 122, Issue 4, 2011, Pages 495-510

Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma

Author keywords

CD133, DNA damage; Glioblastoma; NG2; Peroxiredoxin 1; Radiation resistance

Indexed keywords

ANTINEOPLASTIC AGENT; CD133 ANTIGEN; NESTIN; NEURON GLIAL 2 PROTEIN; PEROXIREDOXIN 1; PROCARBAZINE; TEMOZOLOMIDE; UNCLASSIFIED DRUG; VIMENTIN; VINCRISTINE;

EID: 84860392773     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-011-0867-2     Document Type: Article
Times cited : (119)

References (52)
  • 1
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • DOI 10.1038/nature05236, PII NATURE05236
    • S Bao Q Wu RE McLendon, et al. 2006 Glioma stem cells promote radioresistance by preferential activation of the DNA damage response Nature 444 756 760 17051156 10.1038/nature05236 1:CAS:528:DC%2BD28Xht1OntbzP (Pubitemid 44949604)
    • (2006) Nature , vol.444 , Issue.7120 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3    Hao, Y.4    Shi, Q.5    Hjelmeland, A.B.6    Dewhirst, M.W.7    Bigner, D.D.8    Rich, J.N.9
  • 2
    • 0030043437 scopus 로고    scopus 로고
    • Human homologue of the rat chondroitin sulfate proteoglycan, NG2, detected by monoclonal antibody 7.1, identifies childhood acute lymphoblastic leukemias with t(4;11)(q21;q23) or t(11;19)(q23;p13) and MLL gene rearrangements
    • 8562939 1:CAS:528:DyaK28XnsFGmtA%3D%3D
    • FG Behm FO Smith SC Raimondi CH Pui ID Bernstein 1996 Human homologue of the rat chondroitin sulfate proteoglycan, NG2, detected by monoclonal antibody 7.1, identifies childhood acute lymphoblastic leukemias with t(4;11)(q21;q23) or t(11;19)(q23;p13) and MLL gene rearrangements Blood 87 1134 1139 8562939 1:CAS:528:DyaK28XnsFGmtA%3D%3D
    • (1996) Blood , vol.87 , pp. 1134-1139
    • Behm, F.G.1    Smith, F.O.2    Raimondi, S.C.3    Pui, C.H.4    Bernstein, I.D.5
  • 3
    • 0037437148 scopus 로고    scopus 로고
    • Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons
    • DOI 10.1083/jcb.200210110
    • S Belachew R Chittajallu AA Aguirre, et al. 2003 Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons J Cell Biol 161 169 186 12682089 10.1083/jcb.200210110 1:CAS:528:DC%2BD3sXjtVait7c%3D (Pubitemid 36459089)
    • (2003) Journal of Cell Biology , vol.161 , Issue.1 , pp. 169-186
    • Belachew, S.1    Chittajallu, R.2    Aguirre, A.A.3    Yuan, X.4    Kirby, M.5    Anderson, S.6    Gallo, V.7
  • 4
    • 58149267682 scopus 로고    scopus 로고
    • NG2 expression predicts the metastasis formation in soft-tissue sarcoma patients
    • 18634019 10.1002/jor.20694
    • MS Benassi L Pazzaglia A Chiechi, et al. 2009 NG2 expression predicts the metastasis formation in soft-tissue sarcoma patients J Orthop Res 27 135 140 18634019 10.1002/jor.20694
    • (2009) J Orthop Res , vol.27 , pp. 135-140
    • Benassi, M.S.1    Pazzaglia, L.2    Chiechi, A.3
  • 6
    • 77952329017 scopus 로고    scopus 로고
    • Differentiation therapy exerts antitumor effects on stem-like glioma cells
    • 20442299 10.1158/1078-0432.CCR-09-1800 1:CAS:528:DC%2BC3cXlvF2iu7o%3D
    • B Campos F Wan M Farhadi, et al. 2010 Differentiation therapy exerts antitumor effects on stem-like glioma cells Clin Cancer Res 16 2715 2728 20442299 10.1158/1078-0432.CCR-09-1800 1:CAS:528:DC%2BC3cXlvF2iu7o%3D
    • (2010) Clin Cancer Res , vol.16 , pp. 2715-2728
    • Campos, B.1    Wan, F.2    Farhadi, M.3
  • 9
    • 0036551245 scopus 로고    scopus 로고
    • NG2 proteoglycan promotes angiogenesis-dependent tumor growth in CNS by sequestering angiostatin
    • 11919162 1:CAS:528:DC%2BD38XivVOjtr8%3D
    • M Chekenya M Hjelstuen PO Enger, et al. 2002 NG2 proteoglycan promotes angiogenesis-dependent tumor growth in CNS by sequestering angiostatin Faseb J 16 586 588 11919162 1:CAS:528:DC%2BD38XivVOjtr8%3D
    • (2002) Faseb J , vol.16 , pp. 586-588
    • Chekenya, M.1    Hjelstuen, M.2    Enger, P.O.3
  • 10
    • 51349153709 scopus 로고    scopus 로고
    • The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling
    • 18469852 10.1038/onc.2008.157 1:CAS:528:DC%2BD1cXhtVKrsL%2FN
    • M Chekenya C Krakstad A Svendsen, et al. 2008 The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling Oncogene 27 5182 5194 18469852 10.1038/onc.2008.157 1:CAS:528:DC%2BD1cXhtVKrsL%2FN
    • (2008) Oncogene , vol.27 , pp. 5182-5194
    • Chekenya, M.1    Krakstad, C.2    Svendsen, A.3
  • 13
    • 77950502115 scopus 로고    scopus 로고
    • A hierarchy of self-renewing tumor-initiating cell types in glioblastoma
    • 20385361 10.1016/j.ccr.2009.12.049 1:CAS:528:DC%2BC3cXmsF2msLY%3D
    • R Chen MC Nishimura SM Bumbaca, et al. 2010 A hierarchy of self-renewing tumor-initiating cell types in glioblastoma Cancer Cell 17 362 375 20385361 10.1016/j.ccr.2009.12.049 1:CAS:528:DC%2BC3cXmsF2msLY%3D
    • (2010) Cancer Cell , vol.17 , pp. 362-375
    • Chen, R.1    Nishimura, M.C.2    Bumbaca, S.M.3
  • 14
    • 0035002230 scopus 로고    scopus 로고
    • Increased expression of peroxiredoxin II confers resistance to cisplatin
    • 11396151 1:CAS:528:DC%2BD3MXksVOjt7k%3D
    • YM Chung YD Yoo JK Park YT Kim HJ Kim 2001 Increased expression of peroxiredoxin II confers resistance to cisplatin Anticancer Res 21 1129 1133 11396151 1:CAS:528:DC%2BD3MXksVOjt7k%3D
    • (2001) Anticancer Res , vol.21 , pp. 1129-1133
    • Chung, Y.M.1    Yoo, Y.D.2    Park, J.K.3    Kim, Y.T.4    Kim, H.J.5
  • 15
    • 33748775173 scopus 로고    scopus 로고
    • Dual role of peroxiredoxin I in macrophage-derived foam cells
    • DOI 10.1074/jbc.M605026200
    • JP Conway M Kinter 2006 Dual role of peroxiredoxin I in macrophage-derived foam cells J Biol Chem 281 27991 28001 16880205 10.1074/jbc.M605026200 1:CAS:528:DC%2BD28XpsFOrtbo%3D (Pubitemid 44414512)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.38 , pp. 27991-28001
    • Conway, J.P.1    Kinter, M.2
  • 16
    • 34548313955 scopus 로고    scopus 로고
    • Clonogenic assay of cells in vitro
    • 17406473 10.1038/nprot.2006.339 1:CAS:528:DC%2BD2sXhtFGjtLnI
    • NA Franken HM Rodermond J Stap J Haveman C van Bree 2006 Clonogenic assay of cells in vitro Nat Protoc 1 2315 2319 17406473 10.1038/nprot.2006.339 1:CAS:528:DC%2BD2sXhtFGjtLnI
    • (2006) Nat Protoc , vol.1 , pp. 2315-2319
    • Franken, N.A.1    Rodermond, H.M.2    Stap, J.3    Haveman, J.4    Van Bree, C.5
  • 17
    • 0037444269 scopus 로고    scopus 로고
    • Tissue microarray analysis reveals site-specific prevalence of oncogene amplifications in head and neck squamous cell carcinoma
    • K Freier S Joos C Flechtenmacher, et al. 2003 Tissue microarray analysis reveals site-specific prevalence of oncogene amplifications in head and neck squamous cell carcinoma Cancer Res 63 1179 1182 12649172 1:CAS:528: DC%2BD3sXit1Sgt7s%3D (Pubitemid 36348691)
    • (2003) Cancer Research , vol.63 , Issue.6 , pp. 1179-1182
    • Freier, K.1    Joos, S.2    Flechtenmacher, C.3    Devens, F.4    Benner, A.5    Bosch, F.X.6    Lichter, P.7    Hofele, C.8
  • 21
    • 34447118171 scopus 로고    scopus 로고
    • Elevated peroxiredoxin 1, but not NF-E2-related factor 2, is an independent prognostic factor for disease recurrence and reduced survival in stage I non-small cell lung cancer
    • DOI 10.1158/1078-0432.CCR-06-2893
    • JH Kim PN Bogner N Ramnath, et al. 2007 Elevated peroxiredoxin 1, but not NF-E2-related factor 2, is an independent prognostic factor for disease recurrence and reduced survival in stage I non-small cell lung cancer Clin Cancer Res 13 3875 3882 17606720 10.1158/1078-0432.CCR-06-2893 1:CAS:528:DC%2BD2sXntFymtrs%3D (Pubitemid 47037594)
    • (2007) Clinical Cancer Research , vol.13 , Issue.13 , pp. 3875-3882
    • Kim, J.-H.1    Bogner, P.N.2    Ramnath, N.3    Park, Y.4    Yu, J.5    Park, Y.-M.6
  • 22
    • 33846703755 scopus 로고    scopus 로고
    • Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: Implication to tumor biology
    • DOI 10.1158/0008-5472.CAN-06-2401
    • YJ Kim JY Ahn P Liang, et al. 2007 Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology Cancer Res 67 546 554 17234762 10.1158/0008-5472.CAN-06-2401 1:CAS:528:DC%2BD2sXmtVKlug%3D%3D (Pubitemid 46192191)
    • (2007) Cancer Research , vol.67 , Issue.2 , pp. 546-554
    • Kim, Y.-J.1    Ahn, J.-Y.2    Liang, P.3    Ip, C.4    Zhang, Y.5    Park, Y.-M.6
  • 28
    • 0032755047 scopus 로고    scopus 로고
    • NG2 expression in MLL rearranged acute myeloid leukaemia is restricted to monoblastic cases
    • 10583275 10.1046/j.1365-2141.1999.01730.x 1:CAS:528: DC%2BD3cXhtlKgsA%3D%3D
    • L Mauvieux E Delabesse P Bourquelot, et al. 1999 NG2 expression in MLL rearranged acute myeloid leukaemia is restricted to monoblastic cases Br J Haematol 107 674 676 10583275 10.1046/j.1365-2141.1999.01730.x 1:CAS:528:DC%2BD3cXhtlKgsA%3D%3D
    • (1999) Br J Haematol , vol.107 , pp. 674-676
    • Mauvieux, L.1    Delabesse, E.2    Bourquelot, P.3
  • 29
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • 10.1038/nature07385 1:CAS:528:DC%2BD1cXht1yju77J
    • RFA McLendon D Bigner EG Van Meir DJ Brat GM Mastrogianakis, et al. 2008 Comprehensive genomic characterization defines human glioblastoma genes and core pathways Nature 455 1061 1068 10.1038/nature07385 1:CAS:528:DC%2BD1cXht1yju77J
    • (2008) Nature , vol.455 , pp. 1061-1068
    • McLendon, R.F.A.1    Bigner, D.2    Van Meir, E.G.3    Brat, D.J.4    Mastrogianakis, G.M.5
  • 31
    • 0025743827 scopus 로고
    • The primary structure of NG2, a novel membrane-spanning proteoglycan
    • A Nishiyama KJ Dahlin JT Prince SR Johnstone WB Stallcup 1991 The primary structure of NG2, a novel membrane-spanning proteoglycan J Cell Biol 114 359 371 1906475 10.1083/jcb.114.2.359 1:CAS:528:DyaK38Xhs1ymsr8%3D (Pubitemid 21909807)
    • (1991) Journal of Cell Biology , vol.114 , Issue.2 , pp. 359-371
    • Nishiyama, A.1    Dahlin, K.J.2    Prince, J.T.3    Johnstone, S.R.4    Stallcup, W.B.5
  • 32
    • 0034910990 scopus 로고    scopus 로고
    • Overexpression of peroxiredoxin in human breast cancer
    • 11497302 1:CAS:528:DC%2BD3MXmt1eqtro%3D
    • DY Noh SJ Ahn RA Lee, et al. 2001 Overexpression of peroxiredoxin in human breast cancer Anticancer Res 21 2085 2090 11497302 1:CAS:528: DC%2BD3MXmt1eqtro%3D
    • (2001) Anticancer Res , vol.21 , pp. 2085-2090
    • Noh, D.Y.1    Ahn, S.J.2    Lee, R.A.3
  • 34
    • 20344407807 scopus 로고    scopus 로고
    • Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas
    • H Ohgaki P Kleihues 2005 Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas J Neuropathol Exp Neurol 64 479 489 15977639 1:CAS:528:DC%2BD2MXlvVSgsbg%3D (Pubitemid 40781150)
    • (2005) Journal of Neuropathology and Experimental Neurology , vol.64 , Issue.6 , pp. 479-489
    • Ohgaki, H.1    Kleihues, P.2
  • 35
    • 33645982243 scopus 로고    scopus 로고
    • Expression of peroxiredoxin and thioredoxin in human lung cancer and paired normal lung
    • 16635084 10.1111/j.1440-1843.2006.00849.x
    • JH Park YS Kim HL Lee, et al. 2006 Expression of peroxiredoxin and thioredoxin in human lung cancer and paired normal lung Respirology 11 269 275 16635084 10.1111/j.1440-1843.2006.00849.x
    • (2006) Respirology , vol.11 , pp. 269-275
    • Park, J.H.1    Kim, Y.S.2    Lee, H.L.3
  • 36
    • 0034490213 scopus 로고    scopus 로고
    • Antisense of human peroxiredoxin II enhances radiation-induced cell death
    • 11156252 1:CAS:528:DC%2BD3MXotlersw%3D%3D
    • SH Park YM Chung YS Lee, et al. 2000 Antisense of human peroxiredoxin II enhances radiation-induced cell death Clin Cancer Res 6 4915 4920 11156252 1:CAS:528:DC%2BD3MXotlersw%3D%3D
    • (2000) Clin Cancer Res , vol.6 , pp. 4915-4920
    • Park, S.H.1    Chung, Y.M.2    Lee, Y.S.3
  • 38
    • 77953143517 scopus 로고    scopus 로고
    • Glioma cell populations grouped by different cell type markers drive brain tumor growth
    • 20460538 10.1158/0008-5472.CAN-09-3904 1:CAS:528:DC%2BC3cXmslWgsb4%3D
    • L Prestegarden A Svendsen J Wang, et al. 2010 Glioma cell populations grouped by different cell type markers drive brain tumor growth Cancer Res 70 4274 4279 20460538 10.1158/0008-5472.CAN-09-3904 1:CAS:528:DC%2BC3cXmslWgsb4%3D
    • (2010) Cancer Res , vol.70 , pp. 4274-4279
    • Prestegarden, L.1    Svendsen, A.2    Wang, J.3
  • 40
    • 0036137588 scopus 로고    scopus 로고
    • Peroxiredoxin, a novel family of peroxidases
    • SG Rhee SW Kang TS Chang W Jeong K Kim 2001 Peroxiredoxin, a novel family of peroxidases IUBMB Life 52 35 41 11795591 10.1080/15216540252774748 1:CAS:528:DC%2BD38Xmt12ktg%3D%3D (Pubitemid 33769667)
    • (2001) IUBMB Life , vol.52 , Issue.1-2 , pp. 35-41
    • Rhee, S.G.1    Kang, S.W.2    Chang, T.-S.3    Jeong, W.4    Kim, K.5
  • 41
    • 0027954494 scopus 로고
    • Free radicals in biology: Oxidative stress and the effects of ionizing radiation
    • PA Riley 1994 Free radicals in biology: oxidative stress and the effects of ionizing radiation Int J Radiat Biol 65 27 33 7905906 10.1080/ 09553009414550041 1:CAS:528:DyaK2cXitFWltrw%3D (Pubitemid 24063526)
    • (1994) International Journal of Radiation Biology , vol.65 , Issue.1 , pp. 27-33
    • Riley, P.A.1
  • 42
    • 84987419408 scopus 로고
    • Proposal for a common nomenclature for sequence ions in mass spectra of peptides
    • 6525415 10.1002/bms.1200111109 1:CAS:528:DyaL2MXlvVOgtg%3D%3D
    • P Roepstorff J Fohlman 1984 Proposal for a common nomenclature for sequence ions in mass spectra of peptides Biomed Mass Spectrom 11 601 6525415 10.1002/bms.1200111109 1:CAS:528:DyaL2MXlvVOgtg%3D%3D
    • (1984) Biomed Mass Spectrom , vol.11 , pp. 601
    • Roepstorff, P.1    Fohlman, J.2
  • 43
    • 0026425579 scopus 로고
    • Correlation of chondroitin sulfate proteoglycan expression on proliferating brain capillary endothelial cells with the malignant phenotype of astroglial cells
    • 1893386 1:CAS:528:DyaK3MXlvVSmtrk%3D
    • M Schrappe FG Klier RC Spiro, et al. 1991 Correlation of chondroitin sulfate proteoglycan expression on proliferating brain capillary endothelial cells with the malignant phenotype of astroglial cells Cancer Res 51 4986 4993 1893386 1:CAS:528:DyaK3MXlvVSmtrk%3D
    • (1991) Cancer Res , vol.51 , pp. 4986-4993
    • Schrappe, M.1    Klier, F.G.2    Spiro, R.C.3
  • 45
    • 0030020460 scopus 로고    scopus 로고
    • The human homologue of rat NG2, a chondroitin sulfate proteoglycan, is not expressed on the cell surface of normal hematopoietic cells but is expressed by acute myeloid leukemia blasts from poor-prognosis patients with abnormalities of chromosome band 11q23
    • 8562938 1:CAS:528:DyaK28XnsFGmtw%3D%3D
    • FO Smith C Rauch DE Williams, et al. 1996 The human homologue of rat NG2, a chondroitin sulfate proteoglycan, is not expressed on the cell surface of normal hematopoietic cells but is expressed by acute myeloid leukemia blasts from poor-prognosis patients with abnormalities of chromosome band 11q23 Blood 87 1123 1133 8562938 1:CAS:528:DyaK28XnsFGmtw%3D%3D
    • (1996) Blood , vol.87 , pp. 1123-1133
    • Smith, F.O.1    Rauch, C.2    Williams, D.E.3
  • 46
    • 53049102297 scopus 로고    scopus 로고
    • Decreasing peroxiredoxin II expression decreases glutathione, alters cell cycle distribution, and sensitizes glioma cells to ionizing radiation and H(2)O(2)
    • 18718523 10.1016/j.freeradbiomed.2008.07.015 1:CAS:528:DC%2BD1cXht1SiurrO
    • PS Smith-Pearson M Kooshki DR Spitz, et al. 2008 Decreasing peroxiredoxin II expression decreases glutathione, alters cell cycle distribution, and sensitizes glioma cells to ionizing radiation and H(2)O(2) Free Radic Biol Med 45 8 1178 1189 18718523 10.1016/j.freeradbiomed.2008.07.015 1:CAS:528: DC%2BD1cXht1SiurrO
    • (2008) Free Radic Biol Med , vol.45 , Issue.8 , pp. 1178-1189
    • Smith-Pearson, P.S.1    Kooshki, M.2    Spitz, D.R.3
  • 48
    • 0027228348 scopus 로고
    • Cellular resistance to oxidative stress is accompanied by resistance to cisplatin: The significance of increased catalase activity and total glutathione in hydrogen peroxide-resistant fibroblasts
    • DR Spitz JW Phillips DT Adams, et al. 1993 Cellular resistance to oxidative stress is accompanied by resistance to cisplatin: the significance of increased catalase activity and total glutathione in hydrogen peroxide-resistant fibroblasts J Cell Physiol 156 72 79 8314861 10.1002/jcp.1041560111 1:CAS:528:DyaK3sXltVymtL4%3D (Pubitemid 23211264)
    • (1993) Journal of Cellular Physiology , vol.156 , Issue.1 , pp. 72-79
    • Spitz, D.R.1    Phillips, J.W.2    Adams, D.T.3    Sherman, C.M.4    Deen, D.F.5    Li, G.C.6
  • 50
    • 37849041006 scopus 로고    scopus 로고
    • Experimental iodine-125 seed irradiation of intracerebral brain tumors in nude mice
    • 17897452 10.1186/1748-717X-2-38
    • JJ Verhoeff LJ Stalpers AW Coumou, et al. 2007 Experimental iodine-125 seed irradiation of intracerebral brain tumors in nude mice Radiat Oncol 2 38 17897452 10.1186/1748-717X-2-38
    • (2007) Radiat Oncol , vol.2 , pp. 38
    • Verhoeff, J.J.1    Stalpers, L.J.2    Coumou, A.W.3
  • 51
    • 79960930688 scopus 로고    scopus 로고
    • Targeting the NG2/CSPG4 proteoglycan retards tumour growth and angiogenesis in preclinical models of GBM and melanoma
    • 21829586 10.1371/journal.pone.0023062 1:CAS:528:DC%2BC3MXhtVyksbfO
    • J Wang A Svendsen J Kmiecik, et al. 2011 Targeting the NG2/CSPG4 proteoglycan retards tumour growth and angiogenesis in preclinical models of GBM and melanoma PLoS One 6 7 e23062 21829586 10.1371/journal.pone.0023062 1:CAS:528:DC%2BC3MXhtVyksbfO
    • (2011) PLoS One , vol.6 , Issue.7 , pp. 23062
    • Wang, J.1    Svendsen, A.2    Kmiecik, J.3
  • 52
    • 37849032288 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of siRNA against peroxiredoxin i enhances the radiosensitivity of human intestinal cancer
    • 17976536 10.1016/j.bcp.2007.09.016 1:CAS:528:DC%2BD1cXlvVOhug%3D%3D
    • B Zhang Y Wang K Liu, et al. 2008 Adenovirus-mediated transfer of siRNA against peroxiredoxin I enhances the radiosensitivity of human intestinal cancer Biochem Pharmacol 75 660 667 17976536 10.1016/j.bcp.2007.09.016 1:CAS:528:DC%2BD1cXlvVOhug%3D%3D
    • (2008) Biochem Pharmacol , vol.75 , pp. 660-667
    • Zhang, B.1    Wang, Y.2    Liu, K.3


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