Replacement of the Saccharomyces cerevisiae acetyl-CoA synthetases by alternative pathways for cytosolic acetyl-CoA synthesis

Metabolic Engineering

Volumn 21, Issue , 2014, Pages 46-59

  Kozak, Barbara U ^a   van Rossum, Harmen M ^a   Benjamin, Kirsten R ^b   Wu, Liang ^c   Daran, Jean Marc G ^a   Pronk, Jack T ^a   Van Maris, Antonius J A ^a  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b Amyris Inc   (United States)

^c DSM BIOTECHNOLOGY CENTER   (Netherlands)

Author keywords

Acetylating acetaldehyde dehydrogenase; Metabolic compartments; Precursor supply; Pyruvate formate lyase; Transcriptome; Yeast

Indexed keywords

ACETALDEHYDE; ACETYLATION; BIODEGRADATION; GENE EXPRESSION; GLUCOSE; SYNTHESIS (CHEMICAL);

ACETYLATING ACETALDEHYDE DEHYDROGENASE; METABOLIC COMPARTMENTS; PRECURSOR SUPPLY; PYRUVATE-FORMATE LYASE; TRANSCRIPTOMES;

YEAST;

ACETALDEHYDE; ACETYL COENZYME A; ACETYL COENZYME A SYNTHETASE; ACS2 PROTEIN; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ALDEHYDE DEHYDROGENASE; FORMATE ACETYLTRANSFERASE; FORMIC ACID; GLUCOSE; HISTONE; LIGASE; LYASE; PYROPHOSPHATE; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ANAEROBIC GROWTH; ANIMAL CELL; ARTICLE; BACTERIAL GENE; BIOMASS PRODUCTION; CHEMOSTAT; CONTROLLED STUDY; CYTOSOL; ENZYME MECHANISM; ENZYME SYNTHESIS; FUNGAL STRAIN; FUNGUS GROWTH; GENE CONSTRUCT; GENE EXPRESSION; GROWTH RATE; HISTONE ACETYLATION; HYDROLYSIS; IN VIVO STUDY; METABOLIC ENGINEERING; METABOLITE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; SACCHAROMYCES CEREVISIAE; STOICHIOMETRY; TRANSCRIPTOMICS;

ACETYLATING ACETALDEHYDE DEHYDROGENASE; METABOLIC COMPARTMENTS; PRECURSOR SUPPLY; PYRUVATE-FORMATE LYASE; TRANSCRIPTOME; YEAST;

ACETATE-COA LIGASE; ACETYL COENZYME A; ACETYLTRANSFERASES; ALDEHYDE OXIDOREDUCTASES; BACTERIAL PROTEINS; CYTOSOL; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84896932547     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2013.11.005     Document Type: Article

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