Native chemical ligation for conversion of sequence-defined oligomers into targeted pDNA and siRNA carriers

Journal of Controlled Release

Volumn 180, Issue 1, 2014, Pages 42-50

  Zhang, Can Yang ^a,b   Kos, Petra ^a,c   Müller, Katharina ^a,c   Schrimpf, Waldemar ^c,d   Troiber, Christina ^a   Lächelt, Ulrich ^a,c   Scholz, Claudia ^a,c   Lamb, Don C ^c,d   Wagner, Ernst ^a,c  

^a UNIVERSITY OF MUNICH   (Germany)

^b SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

^c NANOSYSTEMS INITIATIVE MUNICH NIM   (Germany)

^d Munich Center for Integrated Protein Science   (Germany)

Author keywords

Folate; Gene delivery; Library screening; Native chemical ligation; pDNA; siRNA

Indexed keywords

FOLATE; GENE DELIVERY; LIBRARY SCREENING; NATIVE CHEMICAL LIGATION; PDNA; SIRNA;

AMINO ACIDS; GENE TRANSFER; LIGANDS; TOPOLOGY;

OLIGOMERS;

ALANINE; AMIDE; CYSTEINE DERIVATIVE; FOLIC ACID; HISTIDINE; MACROGOL; OLIGOMER; POLYCATION; SMALL INTERFERING RNA; TYROSINE; CYSTEINE; DNA; DRUG CARRIER; MACROGOL DERIVATIVE;

AMINO TERMINAL SEQUENCE; ARTICLE; BIOLOGICAL ACTIVITY; CELL STRAIN KB; CHEMICAL PROCEDURES; CONJUGATION; CONTROLLED STUDY; DNA LIBRARY; GENE TARGETING; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTERNALIZATION; NATIVE CHEMICAL LIGATION; PARTICLE SIZE; PRIORITY JOURNAL; SOLID PHASE SYNTHESIS; ZETA POTENTIAL; ADMINISTRATION AND DOSAGE; ANALOGS AND DERIVATIVES; CELL LINE; CHEMISTRY; GENETICS; PLASMID; RNA INTERFERENCE;

AMIDES; CELL LINE; CYSTEINE; DNA; DRUG CARRIERS; FOLIC ACID; GENE TRANSFER TECHNIQUES; HUMANS; PLASMIDS; POLYETHYLENE GLYCOLS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84896858444     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.02.015     Document Type: Article

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