Structure-activity relationships of siRNA carriers based on sequence-defined oligo (ethane amino) amides

Journal of Controlled Release

Volumn 160, Issue 3, 2012, Pages 532-541

  Fröhlich, Thomas ^a   Edinger, Daniel ^a   Kläger, Raphaela ^a   Troiber, Christina ^a   Salcher, Edith ^a   Badgujar, Naresh ^a   Martin, Irene ^a   Schaffert, David ^a   Cengizeroglu, Arzu ^a   Hadwiger, Philipp ^a   Vornlocher, Hans Peter ^a,b   Wagner, Ernst ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b AXOLABS GMBH   (Germany)

Author keywords

Polymer; Polyplex; siRNA delivery; Transfection; Tumor

Indexed keywords

ACID MOIETY; AMINO NITROGEN; BUILDING BLOCKES; CELL LINES; ETHYLENE DIAMINE; GENE SILENCING; IN-VITRO; LINOLIC ACIDS; MOLECULAR SHAPES; OLIGOMER CHAINS; POLYPLEXES; PROTON SPONGE; REPORTER GENE; SIRNA DELIVERY; SOLID-PHASE; STRUCTURE ACTIVITY RELATIONSHIPS; TETRAETHYLENEPENTAMINE; TRANSFECTION; TRIETHYLENETETRAMINE; TUMOR CELL CYCLE; TUMOR GROWTH;

AMIDES; AMINO ACIDS; CELL CULTURE; GENES; GENETIC ENGINEERING; OLEIC ACID; OLIGOMERS; POLYMERS; RNA; TUMORS; UNSATURATED FATTY ACIDS;

ETHANE;

AMIDE; AMINO ACID; CYSTEINE; ETHYLENEDIAMINE; LINOLEIC ACID; NITROGEN; OLEIC ACID; OLIGO(ETHANE AMINO)AMIDE; OLIGOMER; SMALL INTERFERING RNA; TETRAETHYLENEPENTAMINE; TRIENTINE; UNCLASSIFIED DRUG; UNSATURATED FATTY ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CYCLE ARREST; CONTROLLED STUDY; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; MITOSIS; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN MOTIF; REPORTER GENE; STRUCTURE ACTIVITY RELATION; TUMOR CELL; TUMOR GROWTH;

AMIDES; AMINO ACIDS; ANIMALS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; DRUG CARRIERS; FEMALE; GENE SILENCING; GREEN FLUORESCENT PROTEINS; HUMANS; KINESIN; LIPIDS; LUCIFERASES; MICE; MICE, NUDE; POLYETHYLENEIMINE; RNA, SMALL INTERFERING; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 84861981048     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.03.018     Document Type: Article

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