Side chain conformational averaging in human dihydrofolate reductase

Biochemistry

Volumn 53, Issue 7, 2014, Pages 1134-1145

  Tuttle, Lisa M ^a   Dyson, H Jane ^a   Wright, Peter E ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC INTERMEDIATES; COMPREHENSIVE ANALYSIS; CONFORMATIONAL CHANGE; DIHYDROFOLATE REDUCTASE; MAGNETIC RESONANCE RELAXATION; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATES; SEQUENCE IDENTITY; THREE-DIMENSIONAL STRUCTURE;

ENZYME ACTIVITY; ESCHERICHIA COLI; LIGANDS;

CHAINS;

DIHYDROFOLATE REDUCTASE; HOLOENZYME; LEUCINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ALPHA HELIX; ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; ESCHERICHIA COLI; HUMAN; MOLECULAR DYNAMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY;

CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 84896832020     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi4015314     Document Type: Article

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