Mitochondrial mutations and aging: random drift is insufficient to explain the accumulation of mitochondrial deletion mutants in short-lived animals

Aging Cell

Volumn 12, Issue 4, 2013, Pages 728-731

  Kowald, Axel ^a   Kirkwood, Thomas B L ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Aging; Mathematical model; Mitochondrial mutation

Indexed keywords

MITOCHONDRIAL DNA;

AGING; ARTICLE; GENE DELETION; GENE MUTATION; GENETIC DRIFT; HETEROPLASMY; HUMAN; MITOCHONDRION; PRIORITY JOURNAL; ANIMAL; BIOLOGICAL MODEL; COMPUTER SIMULATION; GENETICS; LONGEVITY; METABOLISM; MUTATION RATE; SPECIES DIFFERENCE; TIME;

ANIMALIA; RODENTIA;

AGING; ANIMALS; COMPUTER SIMULATION; DNA, MITOCHONDRIAL; GENETIC DRIFT; LONGEVITY; MITOCHONDRIA; MODELS, BIOLOGICAL; MUTATION RATE; SEQUENCE DELETION; SPECIES SPECIFICITY; TIME FACTORS;

EID: 84880507874     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12098     Document Type: Article

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