Chemical synthesis and biological activity of the neopetrosiamides and their analogues: Revision of disulfide bond connectivity

Journal of the American Chemical Society

Volumn 132, Issue 5, 2010, Pages 1486-1487

  Liu, Hongqiang ^a   Boudreau, Marc A ^a   Zheng, Jing ^a   Whittal, Randy M ^a   Austin, Pamela ^b   Roskelley, Calvin D ^b   Roberge, Michel ^b   Andersen, Raymond J ^b   Vederas, John C ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ACTIVITIES; CHEMICAL EQUATIONS; CHEMICAL SYNTHESIS; DIASTEREOMERIC; DISULFIDE BOND CONNECTIVITY; DISULFIDE BOND FORMATION; DISULFIDE MAPPING; HPLC ANALYSIS; MARINE SPONGE; METHIONINE SULFOXIDE; NORLEUCINE; SOLID PHASE PEPTIDE SYNTHESIS; TUMOR CELL INVASION;

BIOACTIVITY; CHEMICAL BONDS; COMPLEXATION; PEPTIDES;

SYNTHESIS (CHEMICAL);

AMIDE; DIMETHYL SULFOXIDE; METHIONINE DERIVATIVE; NATURAL PRODUCT; NEOPETROSIAMIDE A; NEOPETROSIAMIDE B; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CHEMICAL REACTION; CONTROLLED STUDY; CROSS LINKING; DEPROTECTION REACTION; DIASTEREOISOMER; DISULFIDE BOND; DRUG ACTIVITY; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; OXIDATION; REACTION ANALYSIS; SPONGE (PORIFERA); STEREOCHEMISTRY;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; DISULFIDES; HUMANS; MOLECULAR SEQUENCE DATA; NEOPLASMS; PEPTIDES, CYCLIC; PORIFERA;

EID: 76149117786     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9102925     Document Type: Article

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