Regioselective formation, using orthogonal cysteine protection, of an α-conotoxin dimer peptide containing four disulfide bonds

Organic Letters

Volumn 5, Issue 16, 2003, Pages 2955-2957

  Cuthbertson, Alan ^a   Indrevoll, Bård ^a  

^a Amersham Health AS   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

CONOTOXIN; CYSTEINE; DIMER; PEPTIDE;

ADDITION REACTION; ARTICLE; DISULFIDE BOND; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATION; STEREOCHEMISTRY;

AMINO ACID SEQUENCE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CONOTOXINS; CYSTEINE; DIMERIZATION; DISULFIDES; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION;

EID: 0141631635     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol035105w     Document Type: Article

References (13)

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12. +, 1481.3
13. For best results, it is important that the DMSO used in the DMSO/TFA oxidation steps is stored under Argon and over molecular sieves.