Chemical synthesis of Escherichia coli STh analogues by regioselective disulfide bond formation: Biological evaluation of an 111In-DOTA-Phe19-STh analogue for specific targeting of human colon cancers

Bioconjugate Chemistry

Volumn 13, Issue 2, 2002, Pages 224-231

  Gali, Hariprasad ^a   Sieckman, Gary L ^b   Hoffman, Timothy J ^a,b,c   Owen, Nellie K ^a   Mazuru, Dana G ^a   Forte, Leonard R ^a,b   Volkert, Wynn A ^a,b  

^a UNIVERSITY OF MISSOURI   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; CELLS; CHLORINE COMPOUNDS; COVALENT BONDS; CYTOLOGY; DIAGNOSIS; DISEASES; ESCHERICHIA COLI; MAMMALS; PEPTIDES; SULFUR COMPOUNDS; TUMORS;

BIOLOGICAL EVALUATION; DISULFIDE BOND FORMATION; DISULPHIDE BONDS; GUANYLATE CYCLASE; HUMAN COLON CANCER; IN-VITRO; IN-VIVO; RECEPTOR BINDING; REGIO-SELECTIVE; STABLE PEPTIDES;

BINDING ENERGY;

ESCHERICHIA COLI;

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; 1,4,7,10-TETRAAZACYCLODODECANE- 1,4,7,10-TETRAACETIC ACID; BACTERIAL TOXIN; DISULFIDE; ENTEROTOXIN; HEAT STABLE TOXIN (E COLI); INDIUM; RADIOPHARMACEUTICAL AGENT; SINGLE HETEROCYCLIC RINGS;

ANIMAL; ARTICLE; BINDING COMPETITION; CANCER TRANSPLANTATION; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; COLON TUMOR; ESCHERICHIA COLI; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IC 50; METABOLISM; MOUSE; MOUSE MUTANT; SYNTHESIS;

ANIMALS; BACTERIAL TOXINS; BINDING, COMPETITIVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLONIC NEOPLASMS; DISULFIDES; ENTEROTOXINS; ESCHERICHIA COLI; FEMALE; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; INDIUM RADIOISOTOPES; INHIBITORY CONCENTRATION 50; MICE; MICE, SCID; MOLECULAR STRUCTURE; NEOPLASM TRANSPLANTATION; RADIOPHARMACEUTICALS; TUMOR CELLS, CULTURED;

EID: 0036009631     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc010062u     Document Type: Article

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