The chaperone protein smggds interacts with small gtpases entering the prenylation pathway by recognizing the last amino acid in the CAAX motif

Journal of Biological Chemistry

Volumn 289, Issue 10, 2014, Pages 6862-6876

  Schuld, Nathan J ^a   Vervacke, Jeffrey S ^b   Lorimer, Ellen L ^a   Simon, Nathan C ^a   Hauser, Andrew D ^a   Barbieri, Joseph T ^a   Distefano, Mark D ^b   Williams, Carol L ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b University of Minnesota   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINS;

CAAX MOTIFS; CANCER THERAPEUTICS; CELLULAR CONTEXTS; GERANYLGERANYLATION; GTPASES; PRENYLATION;

AMINO ACIDS;

AMINO ACID; CHAPERONE; CHAPERONE PROTEIN SMGGDS 558; CHAPERONE PROTEIN SMGGDS 607; CYSTEINYLVALYLISOLEUCYLLEUCINE; CYSTEINYLVALYLISOLEUCYLMETHIONINE; GUANOSINE TRIPHOSPHATASE; K RAS PROTEIN; LEUCINE; PEPTIDE; PHENYLALANYLGLYCYLLYSYLALANYLARGINYLLYSYLLYSYLSERYLSERYLCYSTEINE; PROTEIN RAP1B; THREONYLCYSTEINYLVALYLISOLEUCYLMETHIONINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CAA X MOTIF; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME REGULATION; ENZYME SPECIFICITY; GERANYLGERANYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; PREDICTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PRENYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SEQUENCE ANALYSIS; STRUCTURAL HOMOLOGY;

FTI; GGTI; ISOPRENOID; K-RAS; PROTEIN COMPLEXES; PROTEIN FARNESYLATION; PROTEIN ISOPRENYLATION; RAP1; SMALL GTPASES; SMGGDS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEK293 CELLS; HUMANS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MONOMERIC GTP-BINDING PROTEINS; PRENYLATION; SEQUENCE ANALYSIS, PROTEIN; SOFTWARE;

EID: 84896783691     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.527192     Document Type: Article

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