Farnesyltransferase inhibitor induces rapid growth arrest and blocks p70s6k activation by multiple stimuli

Journal of Biological Chemistry

Volumn 275, Issue 15, 2000, Pages 10796-10801

  Law, Brian K ^a,b   Nørgaard, Peter ^c   Moses, Harold L ^a,b  

^a VANDERBILT INGRAM CANCER CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c GLOSTRUP UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

2 [[2 [[2 [(2 AMINO 3 MERCAPTOPROPYL)AMINO] 3 METHYLPENTYL]OXY] 1 OXO 3 PHENYLPROPYL]AMINO] 4 (METHYLSULFONYL)BUTANOIC ACID ISOPROPYL ESTER; ANTINEOPLASTIC AGENT; CALYCULIN A; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; RAPAMYCIN; RAS PROTEIN; S6 KINASE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DEPHOSPHORYLATION; DNA SYNTHESIS INHIBITION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GROWTH INHIBITION; KERATINOCYTE; MOUSE; NONHUMAN; ONCOGENE K RAS; PRIORITY JOURNAL;

ALKYL AND ARYL TRANSFERASES; ANIMALS; CELL DIVISION; CELL LINE; ENZYME ACTIVATION; ENZYME INHIBITORS; FARNESYLTRANSTRANSFERASE; KERATINOCYTES; METHIONINE; MICE; OXAZOLES; PHOSPHORYLATION; RIBOSOMAL PROTEIN S6 KINASES; SIROLIMUS; TETRADECANOYLPHORBOL ACETATE;

ANIMALIA; OXY;

EID: 0034646716     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.15.10796     Document Type: Article

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