메뉴 건너뛰기




Volumn 5, Issue 2, 2014, Pages

Prostate apoptosis response-4 mediates TGF-β-induced epithelial-to-mesenchymal transition

Author keywords

epithelial to mesenchymal transition (EMT); Par 4; TGF ; XIAP

Indexed keywords

CASPASE; DNA FRAGMENT; MESSENGER RNA; NERVE CELL ADHESION MOLECULE; NEUTRALIZING ANTIBODY; PROTEINASE ACTIVATED RECEPTOR 4; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SNAIL; VIMENTIN; X LINKED INHIBITOR OF APOPTOSIS; ZINC FINGER PROTEIN;

EID: 84896777092     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.7     Document Type: Article
Times cited : (27)

References (49)
  • 1
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2002; 2: 442-454.
    • (2002) Nat Rev Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 2
    • 0035810944 scopus 로고    scopus 로고
    • Genetic programs of epithelial cell plasticity directed by transforming growth factor-beta
    • Zavadil J, Bitzer M, Liang D, Yang YC, Massimi A, Kneitz S et al. Genetic programs of epithelial cell plasticity directed by transforming growth factor-beta. Proc Natl Acad Sci USA 2001; 98: 6686-6691.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6686-6691
    • Zavadil, J.1    Bitzer, M.2    Liang, D.3    Yang, Y.C.4    Massimi, A.5    Kneitz, S.6
  • 3
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery JP, Sleeman JP. Complex networks orchestrate epithelial- mesenchymal transitions. Nat Rev Mol Cell Biol 2006; 7: 131-142.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 4
    • 24644487312 scopus 로고    scopus 로고
    • TGF-beta and epithelial-To-mesenchymal transitions
    • Zavadil J, Bottinger EP. TGF-beta and epithelial-To-mesenchymal transitions. Oncogene 2005; 24: 5764-5774.
    • (2005) Oncogene , vol.24 , pp. 5764-5774
    • Zavadil, J.1    Bottinger, E.P.2
  • 5
    • 34547587877 scopus 로고    scopus 로고
    • Cell size and invasion in TGF-beta-induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway
    • Lamouille S, Derynck R. Cell size and invasion in TGF-beta-induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway. J Cell Biol 2007; 178: 437-451.
    • (2007) J Cell Biol , vol.178 , pp. 437-451
    • Lamouille, S.1    Derynck, R.2
  • 6
    • 44249100929 scopus 로고    scopus 로고
    • TGF beta secreted by B16 melanoma antagonizes cancer gene immunotherapy bystander effect
    • Penafuerte C, Galipeau J. TGF beta secreted by B16 melanoma antagonizes cancer gene immunotherapy bystander effect. Cancer Immunol Immunother 2008; 57: 1197-1206.
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 1197-1206
    • Penafuerte, C.1    Galipeau, J.2
  • 7
    • 84871368562 scopus 로고    scopus 로고
    • Mutant surfactant A2 proteins associated with familial pulmonary fibrosis and lung cancer induce TGF-beta1 secretion
    • Maitra M, Cano CA, Garcia CK. Mutant surfactant A2 proteins associated with familial pulmonary fibrosis and lung cancer induce TGF-beta1 secretion. Proc Natl Acad Sci USA 2012; 109: 21064-21069.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 21064-21069
    • Maitra, M.1    Cano, C.A.2    Garcia, C.K.3
  • 8
    • 84875813805 scopus 로고    scopus 로고
    • Breast tumor and stromal cell responses to TGF-beta and hypoxia in matrix deposition
    • Curran CS, Keely PJ. Breast tumor and stromal cell responses to TGF-beta and hypoxia in matrix deposition. Matrix Biol 2012; 32: 95-105.
    • (2012) Matrix Biol , vol.32 , pp. 95-105
    • Curran, C.S.1    Keely, P.J.2
  • 9
    • 0026560454 scopus 로고
    • TGF-beta: Regulation of extracellular matrix
    • Roberts AB, McCune BK, Sporn MB. TGF-beta: Regulation of extracellular matrix. Kidney Int 1992; 41: 557-559.
    • (1992) Kidney Int , vol.41 , pp. 557-559
    • Roberts, A.B.1    McCune, B.K.2    Sporn, M.B.3
  • 10
    • 84875705913 scopus 로고    scopus 로고
    • Noncanonical WNT-5 A signaling regulates TGF-beta-induced extracellular matrix production by airway smooth muscle cells
    • Kumawat K, Menzen MH, Bos IS, Baarsma HA, Borger P, Roth M et al. Noncanonical WNT-5 A signaling regulates TGF-beta-induced extracellular matrix production by airway smooth muscle cells. FASEB J 2012; 27: 1631-1643.
    • (2012) FASEB J , vol.27 , pp. 1631-1643
    • Kumawat, K.1    Menzen, M.H.2    Bos, I.S.3    Baarsma, H.A.4    Borger, P.5    Roth, M.6
  • 11
    • 80051923056 scopus 로고    scopus 로고
    • TGFbeta-And bleomycin-induced extracellular matrix synthesis is mediated through Akt and mammalian target of rapamycin (mTOR)
    • Goc A, Choudhary M, Byzova TV, Somanath PR. TGFbeta-And bleomycin-induced extracellular matrix synthesis is mediated through Akt and mammalian target of rapamycin (mTOR). J Cell Physiol 2011; 226: 3004-3013.
    • (2011) J Cell Physiol , vol.226 , pp. 3004-3013
    • Goc, A.1    Choudhary, M.2    Byzova, T.V.3    Somanath, P.R.4
  • 12
    • 0242499448 scopus 로고    scopus 로고
    • Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
    • Siegel PM, Massague J. Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer. Nat Rev Cancer 2003; 3: 807-821.
    • (2003) Nat Rev Cancer , vol.3 , pp. 807-821
    • Siegel, P.M.1    Massague, J.2
  • 13
    • 0242285692 scopus 로고    scopus 로고
    • TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression
    • Tang B, Vu M, Booker T, Santner SJ, Miller FR, Anver MR et al. TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression. J Clin Invest 2003; 112: 1116-1124.
    • (2003) J Clin Invest , vol.112 , pp. 1116-1124
    • Tang, B.1    Vu, M.2    Booker, T.3    Santner, S.J.4    Miller, F.R.5    Anver, M.R.6
  • 14
    • 0034785348 scopus 로고    scopus 로고
    • TGF-beta signaling in tumor suppression and cancer progression
    • Derynck R, Akhurst RJ, Balmain A. TGF-beta signaling in tumor suppression and cancer progression. Nat Genet 2001; 29: 117-129.
    • (2001) Nat Genet , vol.29 , pp. 117-129
    • Derynck, R.1    Akhurst, R.J.2    Balmain, A.3
  • 15
    • 4043052971 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions: Twist in development and metastasis
    • Kang Y, Massague J. Epithelial-mesenchymal transitions: Twist in development and metastasis. Cell 2004; 118: 277-279.
    • (2004) Cell , vol.118 , pp. 277-279
    • Kang, Y.1    Massague, J.2
  • 16
    • 34249289041 scopus 로고    scopus 로고
    • Snail Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
    • Peinado H, Olmeda D, Cano A. Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype? Nat Rev Cancer 2007; 7: 415-428.
    • (2007) Nat Rev Cancer , vol.7 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 17
    • 77955540696 scopus 로고    scopus 로고
    • XIAP gene expression and function is regulated by autocrine and paracrine TGF-beta signaling
    • Van Themsche C, Chaudhry P, Leblanc V, Parent S, Asselin E. XIAP gene expression and function is regulated by autocrine and paracrine TGF-beta signaling. Mol Cancer 2010; 9: 216.
    • (2010) Mol Cancer , vol.9 , pp. 216
    • Van Themsche, C.1    Chaudhry, P.2    Leblanc, V.3    Parent, S.4    Asselin, E.5
  • 18
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • Shi Y, Massague J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 2003; 113: 685-700.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 19
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 2003; 425: 577-584.
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 20
    • 84455185071 scopus 로고    scopus 로고
    • Ubiquitin-proteasomal degradation of COX-2 in TGF-beta stimulated human endometrial cells is mediated through endoplasmic reticulum mannosidase I
    • Singh M, Chaudhry P, Parent S, Asselin E. Ubiquitin-proteasomal degradation of COX-2 in TGF-beta stimulated human endometrial cells is mediated through endoplasmic reticulum mannosidase I. Endocrinology 2012; 153: 426-437.
    • (2012) Endocrinology , vol.153 , pp. 426-437
    • Singh, M.1    Chaudhry, P.2    Parent, S.3    Asselin, E.4
  • 21
    • 0043133881 scopus 로고    scopus 로고
    • Identification of a unique core domain of par-4 sufficient for selective apoptosis induction in cancer cells
    • El-Guendy N, Zhao Y, Gurumurthy S, Burikhanov R, Rangnekar VM. Identification of a unique core domain of par-4 sufficient for selective apoptosis induction in cancer cells. Mol Cell Biol 2003; 23: 5516-5525.
    • (2003) Mol Cell Biol , vol.23 , pp. 5516-5525
    • El-Guendy, N.1    Zhao, Y.2    Gurumurthy, S.3    Burikhanov, R.4    Rangnekar, V.M.5
  • 24
    • 0033521923 scopus 로고    scopus 로고
    • Decreased expression of the pro-Apoptotic protein Par-4 in renal cell carcinoma
    • Cook J, Krishnan S, Ananth S, Sells SF, Shi Y, Walther MM et al. Decreased expression of the pro-Apoptotic protein Par-4 in renal cell carcinoma. Oncogene 1999; 18: 1205-1208.
    • (1999) Oncogene , vol.18 , pp. 1205-1208
    • Cook, J.1    Krishnan, S.2    Ananth, S.3    Sells, S.F.4    Shi, Y.5    Walther, M.M.6
  • 26
    • 58149116505 scopus 로고    scopus 로고
    • Apoptosis and tumor resistance conferred by Par-4
    • Zhao Y, Rangnekar VM. Apoptosis and tumor resistance conferred by Par-4. Cancer Biol Ther 2008; 7: 1867-1874.
    • (2008) Cancer Biol Ther , vol.7 , pp. 1867-1874
    • Zhao, Y.1    Rangnekar, V.M.2
  • 27
    • 33947501431 scopus 로고    scopus 로고
    • Transforming growth factor-beta3 increases the invasiveness of endometrial carcinoma cells through phosphatidylinositol 3-kinase-dependent up-regulation of X-linked inhibitor of apoptosis and protein kinase c-dependent induction of matrix metalloproteinase-9
    • Van Themsche C, Mathieu I, Parent S, Asselin E. Transforming growth factor-beta3 increases the invasiveness of endometrial carcinoma cells through phosphatidylinositol 3-kinase-dependent up-regulation of X-linked inhibitor of apoptosis and protein kinase c-dependent induction of matrix metalloproteinase-9. J Biol Chem 2007; 282: 4794-4802.
    • (2007) J Biol Chem , vol.282 , pp. 4794-4802
    • Van Themsche, C.1    Mathieu, I.2    Parent, S.3    Asselin, E.4
  • 28
    • 0032922737 scopus 로고    scopus 로고
    • Insufficient TGF-beta 1 production inactivates the autocrine growth suppressive circuit in human ovarian cancer cell lines
    • Zeinoun Z, Teugels E, De Bleser PJ, Neyns B, Geerts A, De Greve J. Insufficient TGF-beta 1 production inactivates the autocrine growth suppressive circuit in human ovarian cancer cell lines. Anticancer Res 1999; 19: 413-420.
    • (1999) Anticancer Res , vol.19 , pp. 413-420
    • Zeinoun, Z.1    Teugels, E.2    De Bleser, P.J.3    Neyns, B.4    Geerts, A.5    De Greve, J.6
  • 29
    • 0034742410 scopus 로고    scopus 로고
    • Autocrine TGFbeta signaling mediates vitamin D3 analog-induced growth inhibition in breast cells
    • Yang L, Yang J, Venkateswarlu S, Ko T, Brattain MG. Autocrine TGFbeta signaling mediates vitamin D3 analog-induced growth inhibition in breast cells. J Cell Physiol 2001; 188: 383-393.
    • (2001) J Cell Physiol , vol.188 , pp. 383-393
    • Yang, L.1    Yang, J.2    Venkateswarlu, S.3    Ko, T.4    Brattain, M.G.5
  • 30
    • 0036085920 scopus 로고    scopus 로고
    • SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4 ALK5, and ALK7
    • Inman GJ, Nicolas FJ, Callahan JF, Harling JD, Gaster LM, Reith AD et al. SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol Pharmacol 2002; 62: 65-74.
    • (2002) Mol Pharmacol , vol.62 , pp. 65-74
    • Inman, G.J.1    Nicolas, F.J.2    Callahan, J.F.3    Harling, J.D.4    Gaster, L.M.5    Reith, A.D.6
  • 31
    • 77951011176 scopus 로고    scopus 로고
    • Transcriptional regulation of proapoptotic Par-4 by NF-kappaB/p65 and its function in controlling cell kinetics during early events in endometrial tumourigenesis
    • Saegusa M, Hashimura M, Kuwata T, Okayasu I. Transcriptional regulation of proapoptotic Par-4 by NF-kappaB/p65 and its function in controlling cell kinetics during early events in endometrial tumourigenesis. J Pathol 2010; 221: 26-36.
    • (2010) J Pathol , vol.221 , pp. 26-36
    • Saegusa, M.1    Hashimura, M.2    Kuwata, T.3    Okayasu, I.4
  • 32
    • 84860717938 scopus 로고    scopus 로고
    • TGFbeta signaling supports survival and metastasis of endometrial cancer cells
    • Lei X, Wang L, Yang J, Sun LZ. TGFbeta signaling supports survival and metastasis of endometrial cancer cells. Cancer Manag Res 2009; 2009: 15-24.
    • (2009) Cancer Manag Res , vol.2009 , pp. 15-24
    • Lei, X.1    Wang, L.2    Yang, J.3    Sun, L.Z.4
  • 33
    • 79951675378 scopus 로고    scopus 로고
    • Prognostic significance of claudin expression changes in breast cancer with regional lymph node metastasis
    • Szasz AM, Tokes AM, Micsinai M, Krenacs T, Jakab C, Lukacs L et al. Prognostic significance of claudin expression changes in breast cancer with regional lymph node metastasis. Clin Exp Metastasis 2011; 28: 55-63.
    • (2011) Clin Exp Metastasis , vol.28 , pp. 55-63
    • Szasz, A.M.1    Tokes, A.M.2    Micsinai, M.3    Krenacs, T.4    Jakab, C.5    Lukacs, L.6
  • 34
    • 77953528155 scopus 로고    scopus 로고
    • Claudin 1 in breast tumorigenesis: Revelation of a possible novel 'claudin high' subset of breast cancers
    • Myal Y, Leygue E, Blanchard AA. Claudin 1 in breast tumorigenesis: Revelation of a possible novel 'claudin high' subset of breast cancers. J Biomed Biotechnol 2010; 2010: 956897.
    • (2010) J Biomed Biotechnol , vol.2010 , pp. 956897
    • Myal, Y.1    Leygue, E.2    Blanchard, A.A.3
  • 36
    • 18444417781 scopus 로고    scopus 로고
    • Claudin-1 3 and-4 proteins and mRNA expression in benign and malignant breast lesions: A research study
    • Tokes AM, Kulka J, Paku S, Szik A, Paska C, Novak PK et al. Claudin-1,-3 and-4 proteins and mRNA expression in benign and malignant breast lesions: A research study. Breast Cancer Res 2005; 7: R296-R305.
    • (2005) Breast Cancer Res , vol.7
    • Tokes, A.M.1    Kulka, J.2    Paku, S.3    Szik, A.4    Paska, C.5    Novak, P.K.6
  • 37
    • 84856808070 scopus 로고    scopus 로고
    • Prostate apoptosis response 4 (Par-4), a novel substrate of caspase-3 during apoptosis activation
    • Chaudhry P, Singh M, Parent S, Asselin E. Prostate apoptosis response 4 (Par-4), a novel substrate of caspase-3 during apoptosis activation. Mol Cell Biol 2012; 32: 826-839.
    • (2012) Mol Cell Biol , vol.32 , pp. 826-839
    • Chaudhry, P.1    Singh, M.2    Parent, S.3    Asselin, E.4
  • 40
    • 0032101178 scopus 로고    scopus 로고
    • Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-Type 1 gene
    • Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S, Gauthier JM. Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-Type 1 gene. EMBO J 1998; 17: 3091-3100.
    • (1998) EMBO J , vol.17 , pp. 3091-3100
    • Dennler, S.1    Itoh, S.2    Vivien, D.3    Ten Dijke, P.4    Huet, S.5    Gauthier, J.M.6
  • 41
    • 0030872367 scopus 로고    scopus 로고
    • Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic
    • Kim J, Johnson K, Chen HJ, Carroll S, Laughon A. Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic. Nature 1997; 388: 304-308.
    • (1997) Nature , vol.388 , pp. 304-308
    • Kim, J.1    Johnson, K.2    Chen, H.J.3    Carroll, S.4    Laughon, A.5
  • 42
    • 0032110463 scopus 로고    scopus 로고
    • Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2
    • Labbe E, Silvestri C, Hoodless PA,Wrana JL, Attisano L. Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2. Mol Cell 1998; 2: 109-120.
    • (1998) Mol Cell , vol.2 , pp. 109-120
    • Labbe, E.1    Silvestri, C.2    Hoodless, P.A.3    Wrana, J.L.4    Attisano, L.5
  • 43
  • 44
    • 0242585506 scopus 로고    scopus 로고
    • Genetic inactivation of Par4 results in hyperactivation of NF-kappaB and impairment of JNK and p38
    • Garcia-Cao I, Lafuente MJ, Criado LM, Diaz-Meco MT, Serrano M, Moscat J. Genetic inactivation of Par4 results in hyperactivation of NF-kappaB and impairment of JNK and p38. EMBO Rep 2003; 4: 307-312.
    • (2003) EMBO Rep , vol.4 , pp. 307-312
    • Garcia-Cao, I.1    Lafuente, M.J.2    Criado, L.M.3    Diaz-Meco, M.T.4    Serrano, M.5    Moscat, J.6
  • 45
    • 73349108404 scopus 로고    scopus 로고
    • Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin
    • Martinez-Estrada OM, Lettice LA, Essafi A, Guadix JA, Slight J, Velecela V et al. Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin. Nat Genet 2010; 42: 89-93.
    • (2010) Nat Genet , vol.42 , pp. 89-93
    • Martinez-Estrada, O.M.1    Lettice, L.A.2    Essafi, A.3    Guadix, J.A.4    Slight, J.5    Velecela, V.6
  • 46
    • 80054784515 scopus 로고    scopus 로고
    • The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer
    • Dhasarathy A, Phadke D, Mav D, Shah RR, Wade PA. The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer. PLoS ONE 2011; 6: E26514.
    • (2011) PLoS ONE , vol.6
    • Dhasarathy, A.1    Phadke, D.2    Mav, D.3    Shah, R.R.4    Wade, P.A.5
  • 47
    • 36849002930 scopus 로고    scopus 로고
    • The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-Alpha
    • Dhasarathy A, Kajita M, Wade PA. The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-Alpha. Mol Endocrinol 2007; 21: 2907-2918.
    • (2007) Mol Endocrinol , vol.21 , pp. 2907-2918
    • Dhasarathy, A.1    Kajita, M.2    Wade, P.A.3
  • 49
    • 33744775013 scopus 로고    scopus 로고
    • Decidualization and maintenance of a functional prostaglandin system in human endometrial cell lines following transformation with SV40 large T antigen
    • Chapdelaine P, Kang J, Boucher-Kovalik S, Caron N, Tremblay JP, Fortier MA. Decidualization and maintenance of a functional prostaglandin system in human endometrial cell lines following transformation with SV40 large T antigen. Mol Hum Reprod 2006; 12: 309-319.
    • (2006) Mol Hum Reprod , vol.12 , pp. 309-319
    • Chapdelaine, P.1    Kang, J.2    Boucher-Kovalik, S.3    Caron, N.4    Tremblay, J.P.5    Fortier, M.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.