메뉴 건너뛰기




Volumn 59, Issue 3, 2014, Pages 1016-1029

G-protein-coupled receptor 30/adenylyl cyclase/protein kinase A pathway is involved in estradiol 17ß-d-glucuronide-induced cholestasis

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ANTIPORTER; BILE SALT EXPORT PUMP; COLLAGEN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC NUCLEOTIDE; EPIDERMAL GROWTH FACTOR RECEPTOR; ESTRADIOL 17BETA DEXO GLUCURONIDE; ESTRADIOL DERIVATIVE; G PROTEIN COUPLED RECEPTOR 30; GLUCURONIDE; ISOBUTYLMETHYLXANTHINE; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 84896736570     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.26752     Document Type: Article
Times cited : (50)

References (39)
  • 1
    • 0036074018 scopus 로고    scopus 로고
    • Mammalian ABC transporters in health and disease
    • Borst P, Elferink RO. Mammalian ABC transporters in health and disease. Annu Rev Biochem 2002;71:537-592.
    • (2002) Annu Rev Biochem , vol.71 , pp. 537-592
    • Borst, P.1    Elferink, R.O.2
  • 3
    • 0032998834 scopus 로고    scopus 로고
    • Molecular regulation of hepatocellular transport systems in cholestasis
    • Trauner M, Meier PJ, Boyer JL. Molecular regulation of hepatocellular transport systems in cholestasis. J Hepatol 1999;31:165-178.
    • (1999) J Hepatol , vol.31 , pp. 165-178
    • Trauner, M.1    Meier, P.J.2    Boyer, J.L.3
  • 4
    • 63449107281 scopus 로고    scopus 로고
    • Physiology of bile secretion
    • Esteller A. Physiology of bile secretion. World J Gastroenterol 2008;14:5641-5649.
    • (2008) World J Gastroenterol , vol.14 , pp. 5641-5649
    • Esteller, A.1
  • 5
    • 0037483657 scopus 로고    scopus 로고
    • Impaired localisation and transport function of canalicular Bsep in taurolithocholate-induced cholestasis in the rat
    • Crocenzi FA, Mottino AD, Sanchez Pozzi EJ, Pellegrino JM, Rodríguez Garay EA, Milkiewicz P, et al. Impaired localisation and transport function of canalicular Bsep in taurolithocholate-induced cholestasis in the rat. Gut 2003;52:1170-1177.
    • (2003) Gut , vol.52 , pp. 1170-1177
    • Crocenzi, F.A.1    Mottino, A.D.2    Sanchez Pozzi, E.J.3    Pellegrino, J.M.4    Rodríguez Garay, E.A.5    Milkiewicz, P.6
  • 6
    • 0034657167 scopus 로고    scopus 로고
    • Electromicroscopic demonstration of multidrug resistance protein 2 (Mrp2) retrieval from the canalicular membrane in response to hyperosmolarity and lipopolysaccharide
    • Dombrowski F, Kubitz R, Chittattu A, Wettstein M, Saha N, Haussinger D. Electromicroscopic demonstration of multidrug resistance protein 2 (Mrp2) retrieval from the canalicular membrane in response to hyperosmolarity and lipopolysaccharide. Biochem J 2000;348:183-188.
    • (2000) Biochem J , vol.348 , pp. 183-188
    • Dombrowski, F.1    Kubitz, R.2    Chittattu, A.3    Wettstein, M.4    Saha, N.5    Haussinger, D.6
  • 7
    • 0015971947 scopus 로고
    • Recurrent jaundice in pregnancy. IV. Quantitative determination of urinary and biliary estrogens, including studies in pruritus gravidarum
    • Adlercreutz H, Tikkanen MJ, Wichmann K, Svanborg A, Anberg A. Recurrent jaundice in pregnancy. IV. Quantitative determination of urinary and biliary estrogens, including studies in pruritus gravidarum. J Clin Endocrinol Metab 1974;38:51-57.
    • (1974) J Clin Endocrinol Metab , vol.38 , pp. 51-57
    • Adlercreutz, H.1    Tikkanen, M.J.2    Wichmann, K.3    Svanborg, A.4    Anberg, A.5
  • 8
    • 0030740593 scopus 로고    scopus 로고
    • Cholestatic properties and hepatic transport of steroid glucuronides
    • Vore M, Liu Y, Huang L. Cholestatic properties and hepatic transport of steroid glucuronides. Drug Metabol Rev 1997;29:183-203.
    • (1997) Drug Metabol Rev , vol.29 , pp. 183-203
    • Vore, M.1    Liu, Y.2    Huang, L.3
  • 9
    • 0033984873 scopus 로고    scopus 로고
    • Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver
    • Stieger B, Fattinger K, Madon J, Kullak-Ublick GA, Meier PJ. Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver. Gastroenterology 2000;118:422-430.
    • (2000) Gastroenterology , vol.118 , pp. 422-430
    • Stieger, B.1    Fattinger, K.2    Madon, J.3    Kullak-Ublick, G.A.4    Meier, P.J.5
  • 11
    • 42549096967 scopus 로고    scopus 로고
    • Hepatocellular transport in acquired cholestasis: new insights into functional, regulatory and therapeutic aspects
    • Roma MG, Crocenzi FA, Sanchez Pozzi EA. Hepatocellular transport in acquired cholestasis: new insights into functional, regulatory and therapeutic aspects. Clin Sci (Lond) 2008;114:567-588.
    • (2008) Clin Sci (Lond) , vol.114 , pp. 567-588
    • Roma, M.G.1    Crocenzi, F.A.2    Sanchez Pozzi, E.A.3
  • 14
    • 77957949650 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase/protein kinase B signaling pathway is involved in estradiol 17beta-D-glucuronide-induced cholestasis: complementarity with classical protein kinase C
    • Boaglio AC, Zucchetti AE, Sanchez Pozzi EJ, Pellegrino JM, Ochoa JE, Mottino AD, et al. Phosphoinositide 3-kinase/protein kinase B signaling pathway is involved in estradiol 17beta-D-glucuronide-induced cholestasis: complementarity with classical protein kinase C. Hepatology 2010;52:1465-1476.
    • (2010) Hepatology , vol.52 , pp. 1465-1476
    • Boaglio, A.C.1    Zucchetti, A.E.2    Sanchez Pozzi, E.J.3    Pellegrino, J.M.4    Ochoa, J.E.5    Mottino, A.D.6
  • 15
    • 84869138342 scopus 로고    scopus 로고
    • ERK1/2 and p38 MAPKs are complementarily involved in estradiol 17ß-D-glucuronide-induced cholestasis: crosstalk with cPKC and PI3K
    • Boaglio AC, Zucchetti AE, Toledo FD, Barosso IR, Sanchez Pozzi EJ, Crocenzi FA, et al. ERK1/2 and p38 MAPKs are complementarily involved in estradiol 17ß-D-glucuronide-induced cholestasis: crosstalk with cPKC and PI3K. PLoS One 2012;7:e49255.
    • (2012) PLoS One , vol.7
    • Boaglio, A.C.1    Zucchetti, A.E.2    Toledo, F.D.3    Barosso, I.R.4    Sanchez Pozzi, E.J.5    Crocenzi, F.A.6
  • 16
    • 84870284019 scopus 로고    scopus 로고
    • Sequential activation of classic PKC and estrogen receptor alpha is involved in estradiol 17ß-D-glucuronide-induced cholestasis
    • Barosso IR, Zucchetti AE, Boaglio AC, Larocca MC, Taborda DR, Luquita MG, et al. Sequential activation of classic PKC and estrogen receptor alpha is involved in estradiol 17ß-D-glucuronide-induced cholestasis. PLoS One 2012;7:e50711.
    • (2012) PLoS One , vol.7
    • Barosso, I.R.1    Zucchetti, A.E.2    Boaglio, A.C.3    Larocca, M.C.4    Taborda, D.R.5    Luquita, M.G.6
  • 17
    • 33745167352 scopus 로고    scopus 로고
    • 17 beta-estradiol activates PI3K/Akt signaling pathway by estrogen receptor (ER)-dependent and ER-independent mechanisms in endometrial cancer cells
    • Guo RX, Wei LH, Tu Z, Sun PM, Wang JL, Zhao D, et al. 17 beta-estradiol activates PI3K/Akt signaling pathway by estrogen receptor (ER)-dependent and ER-independent mechanisms in endometrial cancer cells. J Steroid Biochem Mol Biol 2006;99:9-18.
    • (2006) J Steroid Biochem Mol Biol , vol.99 , pp. 9-18
    • Guo, R.X.1    Wei, L.H.2    Tu, Z.3    Sun, P.M.4    Wang, J.L.5    Zhao, D.6
  • 18
    • 0032492537 scopus 로고    scopus 로고
    • Estrogens cause rapid activation of IP3-PKC-alpha signal transduction pathway in HEPG2 cells
    • Marino M, Pallottini V, Trentalance A. Estrogens cause rapid activation of IP3-PKC-alpha signal transduction pathway in HEPG2 cells. Biochem Biophys Res Commun 1998;245:254-258.
    • (1998) Biochem Biophys Res Commun , vol.245 , pp. 254-258
    • Marino, M.1    Pallottini, V.2    Trentalance, A.3
  • 19
    • 0031282001 scopus 로고    scopus 로고
    • Identification of a gene (GPR30) with homology to the G-protein-coupled receptor superfamily associated with estrogen receptor expression in breast cancer
    • Carmeci C, Thompson DA, Ring HZ, Francke U, Weigel RJ. Identification of a gene (GPR30) with homology to the G-protein-coupled receptor superfamily associated with estrogen receptor expression in breast cancer. Genomics 1997;45:607-617.
    • (1997) Genomics , vol.45 , pp. 607-617
    • Carmeci, C.1    Thompson, D.A.2    Ring, H.Z.3    Francke, U.4    Weigel, R.J.5
  • 20
    • 70349427029 scopus 로고    scopus 로고
    • New insights into the molecular mechanisms underlying effects of estrogen on cholesterol gallstone formation
    • Wang HH, Liu M, Clegg DJ, Portincasa P, Wang DQ. New insights into the molecular mechanisms underlying effects of estrogen on cholesterol gallstone formation. Biochim Biophys Acta 2009;1791:1037-1047.
    • (2009) Biochim Biophys Acta , vol.1791 , pp. 1037-1047
    • Wang, H.H.1    Liu, M.2    Clegg, D.J.3    Portincasa, P.4    Wang, D.Q.5
  • 22
    • 79953191123 scopus 로고    scopus 로고
    • Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation
    • Copsel S, Garcia C, Diez F, Vermeulem M, Baldi A, Bianciotti LG, et al. Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation. J Biol Chem 2011;286:6979-6988.
    • (2011) J Biol Chem , vol.286 , pp. 6979-6988
    • Copsel, S.1    Garcia, C.2    Diez, F.3    Vermeulem, M.4    Baldi, A.5    Bianciotti, L.G.6
  • 23
    • 80054697486 scopus 로고    scopus 로고
    • Prevention of estradiol 17beta-D-glucuronide-induced canalicular transporter internalization by hormonal modulation of cAMP in rat hepatocytes
    • Zucchetti AE, Barosso IR, Boaglio A, Pellegrino JM, Ochoa EJ, Roma MG, et al. Prevention of estradiol 17beta-D-glucuronide-induced canalicular transporter internalization by hormonal modulation of cAMP in rat hepatocytes. Mol Biol Cell 2011;22:3902-3915.
    • (2011) Mol Biol Cell , vol.22 , pp. 3902-3915
    • Zucchetti, A.E.1    Barosso, I.R.2    Boaglio, A.3    Pellegrino, J.M.4    Ochoa, E.J.5    Roma, M.G.6
  • 24
    • 0029087996 scopus 로고
    • Transport characteristics of three fluorescent conjugated bile acid analogs in isolated rat hepatocytes and couplets
    • Maglova LM, Jackson AM, Meng XJ, Carruth MW, Schteingart CD, Ton-Nu HT, et al. Transport characteristics of three fluorescent conjugated bile acid analogs in isolated rat hepatocytes and couplets. Hepatology 1995;22:637-647.
    • (1995) Hepatology , vol.22 , pp. 637-647
    • Maglova, L.M.1    Jackson, A.M.2    Meng, X.J.3    Carruth, M.W.4    Schteingart, C.D.5    Ton-Nu, H.T.6
  • 25
    • 0033652585 scopus 로고    scopus 로고
    • Control by signaling modulators of the sorting of canalicular transporters in rat hepatocyte couplets: role of the cytoskeleton
    • Roma MG, Milkiewicz P, Elias E, Coleman R. Control by signaling modulators of the sorting of canalicular transporters in rat hepatocyte couplets: role of the cytoskeleton. Hepatology 2000;32:1342-1356.
    • (2000) Hepatology , vol.32 , pp. 1342-1356
    • Roma, M.G.1    Milkiewicz, P.2    Elias, E.3    Coleman, R.4
  • 26
    • 3242890471 scopus 로고    scopus 로고
    • siRNA Selection Server: an automated siRNA oligonucleotide prediction server
    • Yuan B, Latek R, Hossbach M, Tuschl T, Lewitter F. siRNA Selection Server: an automated siRNA oligonucleotide prediction server. Nucleic Acids Res 2004;32(Web Server issue):W130-W134.
    • (2004) Nucleic Acids Res , vol.32
    • Yuan, B.1    Latek, R.2    Hossbach, M.3    Tuschl, T.4    Lewitter, F.5
  • 27
    • 79956061001 scopus 로고    scopus 로고
    • Quantitative time-lapse imaging-based analysis of drug-drug interaction mediated by hepatobiliary transporter, multidrug resistance-associated protein 2, in sandwich-cultured rat hepatocytes
    • Nakanishi T, Shibue Y, Fukuyama Y, Yoshida K, Fukuda H, Shirasaka Y, et al. Quantitative time-lapse imaging-based analysis of drug-drug interaction mediated by hepatobiliary transporter, multidrug resistance-associated protein 2, in sandwich-cultured rat hepatocytes. Drug Metab Dispos 2011;39:984-991.
    • (2011) Drug Metab Dispos , vol.39 , pp. 984-991
    • Nakanishi, T.1    Shibue, Y.2    Fukuyama, Y.3    Yoshida, K.4    Fukuda, H.5    Shirasaka, Y.6
  • 28
    • 33746922414 scopus 로고    scopus 로고
    • Oxidant-induced activation of type I protein kinase A is mediated by RI subunit interprotein disulfide bond formation
    • Brennan JP, Bardswell SC, Burgoyne JR, Fuller W, Schroder E, Wait R, et al. Oxidant-induced activation of type I protein kinase A is mediated by RI subunit interprotein disulfide bond formation. J Biol Chem 2006;281:21827-21836.
    • (2006) J Biol Chem , vol.281 , pp. 21827-21836
    • Brennan, J.P.1    Bardswell, S.C.2    Burgoyne, J.R.3    Fuller, W.4    Schroder, E.5    Wait, R.6
  • 29
    • 34248223712 scopus 로고    scopus 로고
    • Protein kinase A-dependent translocation of Hsp90 alpha impairs endothelial nitric-oxide synthase activity in high glucose and diabetes
    • Lei H, Venkatakrishnan A, Yu S, Kazlauskas A. Protein kinase A-dependent translocation of Hsp90 alpha impairs endothelial nitric-oxide synthase activity in high glucose and diabetes. J Biol Chem 2007;282:9364-9371.
    • (2007) J Biol Chem , vol.282 , pp. 9364-9371
    • Lei, H.1    Venkatakrishnan, A.2    Yu, S.3    Kazlauskas, A.4
  • 31
    • 0347359224 scopus 로고    scopus 로고
    • Localized effects of cAMP mediated by distinct routes of protein kinase A
    • Tasken K, Aandahl EM. Localized effects of cAMP mediated by distinct routes of protein kinase A. Physiol Rev 2004;84:137-167.
    • (2004) Physiol Rev , vol.84 , pp. 137-167
    • Tasken, K.1    Aandahl, E.M.2
  • 32
    • 34247895595 scopus 로고    scopus 로고
    • G protein-coupled receptor 30-dependent protein kinase A pathway is critical in nongenomic effects of estrogen in attenuating liver injury after trauma-hemorrhage
    • Hsieh YC, Yu HP, Frink M, Suzuki T, Choudhry MA, Schwacha MG, et al. G protein-coupled receptor 30-dependent protein kinase A pathway is critical in nongenomic effects of estrogen in attenuating liver injury after trauma-hemorrhage. Am J Pathol 2007;170:1210-1218.
    • (2007) Am J Pathol , vol.170 , pp. 1210-1218
    • Hsieh, Y.C.1    Yu, H.P.2    Frink, M.3    Suzuki, T.4    Choudhry, M.A.5    Schwacha, M.G.6
  • 33
    • 70450233487 scopus 로고    scopus 로고
    • D-AKAP2 interacts with Rab4 and Rab11 through its RGS domains and regulates transferrin receptor recycling
    • Eggers CT, Schafer JC, Goldenring JR, Taylor SS. D-AKAP2 interacts with Rab4 and Rab11 through its RGS domains and regulates transferrin receptor recycling. J Biol Chem 2009;284:32869-32880.
    • (2009) J Biol Chem , vol.284 , pp. 32869-32880
    • Eggers, C.T.1    Schafer, J.C.2    Goldenring, J.R.3    Taylor, S.S.4
  • 34
    • 84896727372 scopus 로고    scopus 로고
    • Role of calcium-calmoduline pathway in estradiol-17-ß-D-glucuronide induced impairment of canalicular secretion in isolated rat hepatocyte couplet
    • Zucchetti AE, Toledo FD, Barosso IR, Crocenzi FA, Sanchez-Pozzi EJ. Role of calcium-calmoduline pathway in estradiol-17-ß-D-glucuronide induced impairment of canalicular secretion in isolated rat hepatocyte couplet. J Hepatol 2010;52:386.
    • (2010) J Hepatol , vol.52 , pp. 386
    • Zucchetti, A.E.1    Toledo, F.D.2    Barosso, I.R.3    Crocenzi, F.A.4    Sanchez-Pozzi, E.J.5
  • 35
    • 0034623827 scopus 로고    scopus 로고
    • Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C
    • Kamp TJ, Hell JW. Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C. Circ Res 2000;87:1095-1102.
    • (2000) Circ Res , vol.87 , pp. 1095-1102
    • Kamp, T.J.1    Hell, J.W.2
  • 37
    • 84855987132 scopus 로고    scopus 로고
    • Activity-dependent modulation of endocytosis by calmodulin at a large central synapse
    • Yao L, Sakaba T. Activity-dependent modulation of endocytosis by calmodulin at a large central synapse. Proc Natl Acad Sci U S A 2012;109:291-296.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 291-296
    • Yao, L.1    Sakaba, T.2
  • 38
    • 34547095246 scopus 로고    scopus 로고
    • Estrogen signaling via a linear pathway involving insulin-like growth factor I receptor, matrix metalloproteinases, and epidermal growth factor receptor to activate mitogen-activated protein kinase in MCF-7 breast cancer cells
    • Song RX, Zhang Z, Chen Y, Bao Y, Santen RJ. Estrogen signaling via a linear pathway involving insulin-like growth factor I receptor, matrix metalloproteinases, and epidermal growth factor receptor to activate mitogen-activated protein kinase in MCF-7 breast cancer cells. Endocrinology 2007;148:4091-4101.
    • (2007) Endocrinology , vol.148 , pp. 4091-4101
    • Song, R.X.1    Zhang, Z.2    Chen, Y.3    Bao, Y.4    Santen, R.J.5
  • 39
    • 0031979439 scopus 로고    scopus 로고
    • Cyclic AMP stimulates sorting of the canalicular organic anion transporter (Mrp2/cMoat) to the apical domain in hepatocyte couplets
    • Roelofsen H, Soroka CJ, Keppler D, Boyer JL. Cyclic AMP stimulates sorting of the canalicular organic anion transporter (Mrp2/cMoat) to the apical domain in hepatocyte couplets. J Cell Sci 1998;111:1137-1145.
    • (1998) J Cell Sci , vol.111 , pp. 1137-1145
    • Roelofsen, H.1    Soroka, C.J.2    Keppler, D.3    Boyer, J.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.