PKA phosphorylation of cardiac ryanodine receptor modulates SR luminal Ca 2+ sensitivity

Journal of Molecular and Cellular Cardiology

Volumn 53, Issue 1, 2012, Pages 33-42

  Ullrich, Nina D ^a   Valdivia, Héctor H ^b,c   Niggli, Ernst ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Ca 2+ imaging; Excitation contraction coupling; PKA; Ryanodine receptor phosphorylation; Sarcoplasmic reticulum

Indexed keywords

BETA ADRENERGIC RECEPTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CHANNEL L TYPE; CYCLIC AMP DEPENDENT PROTEIN KINASE; RYANODINE RECEPTOR 2;

ADAPTATION; ADRENERGIC SYSTEM; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BETA ADRENERGIC STIMULATION; CALCIUM SIGNALING; CALCIUM TRANSPORT; CARDIAC RESYNCHRONIZATION THERAPY; CONTROLLED STUDY; ENZYME SPECIFICITY; MEMBRANE DEPOLARIZATION; MOLECULAR DYNAMICS; MOUSE; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SARCOPLASMIC RETICULUM; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ADRENERGIC BETA-AGONISTS; ANIMALS; CALCIUM; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DIASTOLE; EXCITATION CONTRACTION COUPLING; LIPID BILAYERS; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PHOSPHORYLATION; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM;

MUS MUSCULUS;

EID: 84861971194     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2012.03.015     Document Type: Article

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