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Bioorganic and Medicinal Chemistry

Volumn 22, Issue 5, 2014, Pages 1690-1699

Synthesis and anticancer activity of focused compound libraries from the natural product lead, oroidin

(5) Dyson, Lauren a Wright, Anthony D b Young, Kelly A a Sakoff, Jennette A c McCluskey, Adam a

a UNIVERSITY OF NEWCASTLE (Australia)

b UNIVERSITY OF HAWAII AT HILO (United States)

c CALVARY MATER NEWCASTLE HOSPITAL (Australia)

Author keywords

Cytotoxic compound; Focused libraries; Natural product leads; Oroidin; Sponges; Synthesis

Indexed keywords

4,5 DIBROMO N (2,2 DIPHENYLETHYL) 1H PYRROLE 2 CARBOXAMIDE; 4,5 DIBROMO N (3 PHENYLPROPYL) 1H PYRROLE 2 CARBOXAMIDE; 4,5 DIBROMO N (3,4 DICHLOROBENZYL) 1H PYRROLE 2 CARBOXAMIDE; 4,5 DIBROMO N (4 CHLOROBENZYL) 1H PYRROLE 2 CARBOXAMIDE; 4,5 DIBROMO N (4 ETHYLPHENETHYL) 1H PYRROLE 2 CARBOXAMIDE; 4,5 DIBROMO N (4 HYDROXYPHENETHYL) 1H PYRROLE 2 CARBOXAMIDE; 4,5 DIBROMO N (4 METHOXYBENZYL) 1H PYRROLE 2 CARBOXAMIDE; 4,5 DIBROMO N (4 PHENYLBUTYL) 1H PYRROLE 2 CARBOXAMIDE; 4,5 DIBROMO N PHENETHYL 1H PYRROLE 2 CARBOXAMIDE; 4,5 DIBROMO N [2 ( NAPHTHALEN 2 YL)ETHYL] 1H PYRROLE 2 CARBOXAMIDE; AMIDE; ANTINEOPLASTIC AGENT; N (2,2 DIPHENYLETHYL) 1H PYRROLE 2 CARBOXAMIDE; N (3 PHENYLPROPYL) 1H PYRROLE 2 CARBOXAMIDE; N (3,4 DICHLOROBENZYL) 1H PYRROLE 2 CARBOXAMIDE; N (4 CHLOROBENZYL) 1H PYRROLE 2 CARBOXAMIDE; N (4 ETHYLPHENETHYL) 1H PYRROLE 2 CARBOXAMIDE; N (4 HYDROXYPHENETHYL) 1H PYRROLE 2 CARBOXAMIDE; N (4 METHOXYBENZYL) 1H PYRROLE 2 CARBOXAMIDE; N (4 PHENYLBUTYL) 1H PYRROLE 2 CARBOXAMIDE; N (BIPHENYL 4 YLMETHYL) 1H PYRROLE 2 CARBOXAMIDE; N (BIPHENYL 4 YLMETHYL) 4,5 DIBROMO 1H PYRROLE 2 CARBOXAMIDE; N BENZYL 4,5 DIBROMO 1H PYRROLE 2 CARBOXAMIDE; N PHENETHYL 1H PYRROLE 2 CARBOXAMIDE; N [2 (1H IMIDAZOL 4 YL)ETHYL] 1H PYRROLE 2 CARBOXAMIDE; N [2 (NAPHTHALEN 2 YL)ETHYL] 1H PYRROLE 2 CARBOXAMIDE; N [3 (1H PYRAZOL 1 YL)PROPYL] 1H PYRROLE 2 CARBOXAMIDE; N [3 (2 METHYL 1H IMIDAZOL 1 YL)PROPYL] 1H PYRROLE 2 CARBOXAMIDE; OROIDIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; BIOLOGICAL PRODUCT; PYRROLE DERIVATIVE;

AGELAS OROIDES; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL GROWTH; CELL STRAIN MCF 7; COLON; COLON CANCER; CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; GROWTH INHIBITION; HUMAN; NEUROBLASTOMA; PANCREAS; PROSTATE; SKIN; SPONGE (PORIFERA); ANIMAL; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AGELAS OROIDES;

ANIMALS; BIOLOGICAL PRODUCTS; CELL PROLIFERATION; MOLECULAR STRUCTURE; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84896735156 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2014.01.021 Document Type: Article

Times cited : (34)

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