Synthesis and evaluation of novel ellipticines as potential anti-cancer agents

Organic and Biomolecular Chemistry

Volumn 11, Issue 8, 2013, Pages 1334-1344

  Deane, Fiona M ^a   O'Sullivan, Elaine C ^a   Maguire, Anita R ^a   Gilbert, Jayne ^b   Sakoff, Jennette A ^b,c   McCluskey, Adam ^c   McCarthy, Florence O ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b CALVARY MATER NEWCASTLE HOSPITAL   (Australia)

^c UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-CANCER AGENTS; CANCER CHEMOTHERAPY; DNA INTERCALATIONS; DNA TOPOISOMERASE I; INHIBITORY COMPOUNDS; INTERCALATING AGENTS; MEDICINAL CHEMISTRY; TOPOISOMERASE INHIBITIONS;

ALKYLATION; CELL CULTURE; CHEMOTHERAPY; DISEASES; INTERCALATION; SALTS; SYNTHESIS (CHEMICAL);

IODINE;

ANTINEOPLASTIC AGENT; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE INHIBITOR; ELLIPTICINE DERIVATIVE; GYRASE INHIBITOR;

ARTICLE; CELL PROLIFERATION; CELL STRAIN HT29; CELL STRAIN MCF 7; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; HUMAN; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ELLIPTICINES; HT29 CELLS; HUMANS; MCF-7 CELLS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; TOPOISOMERASE I INHIBITORS; TOPOISOMERASE II INHIBITORS;

EID: 84875859957     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/c2ob27186a     Document Type: Article

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