Cis-regulatory variants affect CHRNA5 mRNA expression in populations of African and European ancestry

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Wang, Jen Chyong ^a   Spiegel, Noah ^a   Bertelsen, Sarah ^a   Le, Nhung ^a   McKenna, Nicholas ^a   Budde, John P ^a   Harari, Oscar ^a   Kapoor, Manav ^a   Brooks, Andrew ^b   Hancock, Dana ^c   Tischfield, Jay ^b   Foroud, Tatiana ^d   Bierut, Laura J ^a   Steinbach, Joe Henry ^a   Edenberg, Howard J ^d   Traynor, Bryan J ^e   Goate, Alison M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c RTI INTERNATIONAL   (United States)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA;

AFRICAN AMERICAN; ALLELIC IMBALANCE; ARTICLE; CAUCASIAN; CHRNA5 GENE; CONTROLLED STUDY; FRONTAL CORTEX; GENE; GENE EXPRESSION; GENETIC ASSOCIATION; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOBLASTOID CELL; NUCLEOTIDE SEQUENCE; PSMA4 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SUBSTANCE ABUSE;

AFRICAN CONTINENTAL ANCESTRY GROUP; ALLELES; ALLELIC IMBALANCE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FRONTAL LOBE; GENE EXPRESSION REGULATION; GENE ORDER; GENOTYPE; HUMANS; MULTIGENE FAMILY; NERVE TISSUE PROTEINS; ORGAN SPECIFICITY; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, NICOTINIC; REGULATORY SEQUENCES, RIBONUCLEIC ACID; RNA ISOFORMS;

EID: 84896731443     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080204     Document Type: Article

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