In Vitro and Ex Vivo analysis of CHRNA3 and CHRNA5 haplotype expression

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Doyle, Glenn A ^a   Wang, Min Jung ^a   Chou, Andrew D ^a   Oleynick, John U ^b   Arnold, Steven E ^a   Buono, Russell J ^c   Ferraro, Thomas N ^a   Berrettini, Wade H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b JOHNSON AND JOHNSON   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LUCIFERASE; NICOTINE; CHRNA5 PROTEIN, HUMAN; NERVE PROTEIN; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR SUBUNIT ALPHA3; TRANSCRIPTION FACTOR SP1;

5' UNTRANSLATED REGION; ALLELE; ARTICLE; BRAIN TISSUE; CHRNA3 GENE; CHRNA5 GENE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE; GENE DELETION; GENE EXPRESSION; GENETIC RISK; GENETIC VARIABILITY; HAPLOTYPE; HETEROZYGOTE; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR CLONING; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM; TOBACCO DEPENDENCE; TRANSCRIPTION INITIATION SITE; AUTOPSY; BINDING SITE; BRAIN; CAUCASIAN; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HELA CELL; METABOLISM; MUTATION; PROTEIN BINDING; RISK FACTOR; TUMOR CELL LINE;

5' UNTRANSLATED REGIONS; AUTOPSY; BINDING SITES; BRAIN; CELL LINE, TUMOR; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HELA CELLS; HUMANS; LUCIFERASES; MUTATION; NERVE TISSUE PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, NICOTINIC; RISK FACTORS; SP1 TRANSCRIPTION FACTOR; TOBACCO USE DISORDER;

EID: 80051615692     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023373     Document Type: Article

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