Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5

Human Molecular Genetics

Volumn 18, Issue 16, 2009, Pages 3125-3135

  Wang, Jen C ^a   Cruchaga, Carlos ^a   Saccone, Nancy L ^a   Bertelsen, Sarah ^a   Liu, Pengyuan ^a   Budde, John P ^a   Duan, Weimin ^a   Fox, Louis ^a   Grucza, Richard A ^a   Kern, Jason ^a   Mayo, Kevin ^a   Reyes, Oliver ^a   Rice, John ^a   Saccone, Scott F ^a   Spiegel, Noah ^a   Steinbach, Joseph H ^a   Stitzel, Jerry A ^b   Anderson, Marshall W ^c   You, Ming ^a   Stevens, Victoria L ^d   Bierut, Laura J ^a   Goate, Alison M ^a   Breslau, N ^e   Culverhouse, R ^a   Hatsukami, D ^f   Hinrichs, A ^a   Johnson, Eric ^g   Vikis, Haris ^a   Lu, Yan ^a   Wang, Yian ^a   Yang, Ping ^h   Pinney, Susan M ⁱ   Petersen, Gloria M ^h   de Andrade, Mariza ^h   Schwartz, Ann G ^j   Gazdar, Adi ^k   Gaba, Colette ^l   Mandal, Diptasri ^m   Kupert, Elena ⁱ   Lee, Juwon ⁱ   Seminara, Daniela ⁿ   Fain, Pamela R ^o   Minna, John ^k   Bailey Wilson, Joan E ^p   Li, Yafang ^q   Amos, Christopher I ^q   more..

^a WASHINGTON UNIVERSITY   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d AMERICAN CANCER SOCIETY   (United States)

^e MICHIGAN STATE UNIVERSITY   (United States)

^f UNIVERSITY OF MINNESOTA   (United States)

^g RTI INTERNATIONAL   (United States)

^h MAYO CLINIC   (United States)

ⁱ UNIVERSITY OF CINCINNATI   (United States)

^j KARMANOS CANCER INSTITUTE   (United States)

^k UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^l MEDICAL COLLEGE OF OHIO   (United States)

^m LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

ⁿ NATIONAL CANCER INSTITUTE   (United States)

^o UNIVERSITY OF COLORADO   (United States)

^p NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^q UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA3; NICOTINIC RECEPTOR ALPHA5; NICOTINIC RECEPTOR BETA4; UNCLASSIFIED DRUG;

ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; BIOLOGICAL ACTIVITY; BRAIN; CANCER RISK; CONTROLLED STUDY; FEMALE; GENE ACTIVITY; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; LUNG CANCER; LUNG CARCINOGENESIS; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; TOBACCO DEPENDENCE;

ALLELES; AMINO ACID SUBSTITUTION; BRAIN; COHORT STUDIES; FEMALE; GENE EXPRESSION; HUMANS; LUNG NEOPLASMS; MALE; RECEPTORS, NICOTINIC; RISK FACTORS; RNA, MESSENGER; TOBACCO USE DISORDER;

EID: 68049090045     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddp231     Document Type: Article

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