Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1

Cancer Research

Volumn 69, Issue 19, 2009, Pages 7844-7850

  Yan, Liu ^a   Pengyuan, Liu ^a   Weidong, Wen ^a   James, Michael A ^a   Yian, Wang ^a   Bailey Wilson, Joan E ^b   Amos, Christopher I ^c   Pinney, Susan M ^d   Ping, Yang ^e   De Andrade, Mariza ^e   Petersen, Gloria M ^e   Wiest, Jonathan S ^f   Fain, Pamela R ^g   Schwartz, Ann G ^h   Gazdar, Adi ⁱ   Gaba, Colette ^j   Rothschild, Henry ^k   Mandal, Diptasri ^k   Kupert, Elena ^d   Lee, Juwon ^d   Seminara, Daniela ^f   Minna, John ⁱ   Anderson, Marshall W ^d   Ming, You ^a   more..

^a USA   (United States)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d UNIVERSITY OF CINCINNATI   (United States)

^e Mayo Clinic   (United States)

^f NATIONAL CANCER INSTITUTE   (United States)

^g UNIVERSITY OF COLORADO   (United States)

^h KARMANOS CANCER INSTITUTE   (United States)

ⁱ UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^j MEDICAL COLLEGE OF OHIO   (United States)

^k LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; NICOTINIC RECEPTOR; PROTEASOME;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER SUSCEPTIBILITY; CANCER THERAPY; CELL PROLIFERATION; CHRNA3 GENE; CHRNA5 GENE; CHRNB4 GENE; CHROMOSOME 15Q; CHROMOSOME 15Q24-25.1; COMPARATIVE STUDY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GENE; GENE EXPRESSION; GENE LOCUS; GENETIC ANALYSIS; GENETIC EPIDEMIOLOGY; HAPLOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INBORN ERROR OF METABOLISM; LUNG NON SMALL CELL CANCER; LUNG PARENCHYMA; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PSMA4 GENE; TUMOR GENE;

CARCINOMA, NON-SMALL-CELL LUNG; CELL GROWTH PROCESSES; CELL LINE, TUMOR; CHROMOSOMES, HUMAN, PAIR 15; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; LUNG NEOPLASMS; PHYSICAL CHROMOSOME MAPPING; PROTEASOME ENDOPEPTIDASE COMPLEX;

EID: 70350215708     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-1833     Document Type: Article

References (21)

1. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2008. CA Cancer J Clin 2008;58:71-96.
2. Dubey S, Powell CA. Update in lung cancer 2007. Am J Respir Crit Care Med 2008;177:941-946
3. Hecht SS. DNA adduct formation from tobacco-specific N-nitrosamines. Mutat Res 1999;424:127-142
4. Mossman BT, Lounsbury KM, Reddy SP. Oxidants and signaling by mitogen-activated protein kinases in lung epithelium. Am J Respir Cell Mol Biol 2006;34: 666-669 (Pubitemid 43825330)
5. Heeschen C, Jang JJ, Weis M, et al. Nicotine stimulates angiogenesis and promotes tumor growth and atherosclerosis. Nat Med 2001;7:833-839 (Pubitemid 32691639)
6. Heeschen C, Weis M, Aicher A, Dimmeler S, Cooke JP. A novel angiogenic pathway mediated by non-neuronal nicotinic acetylcholine receptors. J Clin Invest 2002;110: 527-536 (Pubitemid 34919707)
7. Heeschen C, Weis M, Cooke JP. Nicotine promotes arteriogenesis. J Am Coll Cardiol 2003;41:489-496
8. Lindstrom J. Nicotinic acetylcholine receptors in health and disease. Mol Neurobiol 1997;15:193-222. (Pubitemid 127719578)
9. Thorgeirsson TE, Geller F, Sulem P, et al. A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature 2008;452:638-642
10. Amos CI, Wu X, Broderick P, et al. Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat Genet 2008;40: 616-622 (Pubitemid 351601203)
11. Hung RJ, McKay JD, Gaborieau V, et al. A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature 2008; 452:633-637
12. Liu P, Vikis HG, Wang D, et al. Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. J Natl Cancer Inst 2008;100:1326-1330
13. LaVaute T, Smith S, Cooperman S, et al. Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice. Nat Genet 2001; 27:209-214 (Pubitemid 32157451)
14. Nandi D, Woodward E, Ginsburg DB, Monaco JJ. Intermediates in the formation of mouse 20S proteasomes: implications for the assembly of precursor β subunits. EMBO J 1997;16:5363-5375 (Pubitemid 27380144)
15. Davoli R, Fontanesi L, Russo V, et al. The porcine proteasome subunit A4 (PSMA4) gene: isolation of a partial cDNA, linkage and physical mapping. Anim Genet 1998;29:385-388 (Pubitemid 28501341)
16. Eguchi H, Herschenhous N, Kuzushita N, Moss SF. Helicobacter pylori increases proteasome-mediated degradation of p27(kip1) in gastric epithelial cells. Cancer Res 2003;63:4739-4746 (Pubitemid 36951055)
17. Berrettini W, Yuan X, Tozzi F, et al. α-5/α-3 nicotinic receptor subunit alleles increase risk for heavy smoking. Mol Psychiatry 2008;13:368-373
18. Bierut LJ, Stitzel JA, Wang JC, et al. Variants in nicotinic receptors and risk for nicotine dependence. Am J Psychiatry 2008;165:1163-1171
19. Stevens VL, Bierut LJ, Talbot JT, et al. Nicotinic receptor gene variants influence susceptibility to heavy smoking. Cancer Epidemiol Biomarkers Prev 2008;17: 3517-3525
20. McConkey DJ, Zhu K. Mechanisms of proteasome inhibitor action and resistance in cancer. Drug Resist Updat 2008;11:164-179
21. Saccone SF, Hinrichs AL, Saccone NL, et al. Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Hum Mol Genet 2007; 16:36-49.