A p53 drug response signature identifies prognostic genes in high-risk neuroblastoma

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Barbieri, Eveline ^a   De Preter, Katleen ^b   Capasso, Mario ^c   Johansson, Peter ^d   Man, Tsz Kwong ^a   Chen, Zaowen ^a   Stowers, Paris ^a   Tonini, Gian Paolo ^e   Speleman, Frank ^b   Shohet, Jason M ^a  

^a CENTER FOR CELL AND GENE THERAPY   (United States)

^b GHENT UNIVERSITY HOSPITAL   (Belgium)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

LENTIVIRUS VECTOR; NUTLIN 3; PROTEIN P53; SHORT HAIRPIN RNA;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIOINFORMATICS; CANCER CELL CULTURE; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER RESISTANCE; CANCER RISK; CARCINOGENESIS; CHAF1A GENE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE COURSE; DNA REPLICATION; DNA TRANSCRIPTION; DOWN REGULATION; DRUG RESPONSE; GENE ACTIVATION; GENE AMPLIFICATION; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE REPRESSION; HIGH RISK PATIENT; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MCM3 GENE; MCM6 GENE; NEUROBLASTOMA; NONHUMAN; OUTCOME ASSESSMENT; OVERALL SURVIVAL; POLYMERASE CHAIN REACTION; PROGRESSION FREE SURVIVAL; QUALITATIVE ANALYSIS; RRM2 GENE; TRANSCRIPTION REGULATION; TUMOR REGRESSION; TUMOR SUPPRESSOR GENE; UPREGULATION; VIRAL GENE DELIVERY SYSTEM;

APOPTOSIS; CELL LINE, TUMOR; HCT116 CELLS; HUMANS; IMIDAZOLES; NEUROBLASTOMA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PIPERAZINES; PROGNOSIS; PROTO-ONCOGENE PROTEINS C-MDM2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84896714838     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079843     Document Type: Article

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