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Volumn 8, Issue 11, 2013, Pages

GPR35 activation reduces Ca2+ transients and contributes to the kynurenic acid-dependent reduction of synaptic activity at CA3-CA1 synapses

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BUNGAROTOXIN RECEPTOR; CALCIUM ION; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 35; KYNURENIC ACID; N METHYL DEXTRO ASPARTIC ACID; PHOSPHODIESTERASE V; UNCLASSIFIED DRUG; ZAPRINAST;

EID: 84896700631     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0082180     Document Type: Article
Times cited : (63)

References (54)
  • 2
    • 78649859393 scopus 로고    scopus 로고
    • Identification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of ß-arrestin-2 and activate Gα13
    • doi:10.1042/BJ20101287. PubMed: 20919992
    • Jenkins L, Brea J, Smith NJ, Hudson BD, Reilly G et al. (2010) Identification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of ß-arrestin-2 and activate Gα13. Biochem J 432: 451-459. doi:10.1042/BJ20101287. PubMed: 20919992.
    • (2010) Biochem J , vol.432 , pp. 451-459
    • Jenkins, L.1    Brea, J.2    Smith, N.J.3    Hudson, B.D.4    Reilly, G.5
  • 3
    • 36248949170 scopus 로고    scopus 로고
    • GPR35 is a functional receptor in rat dorsal root ganglion neurons
    • DOI 10.1016/j.bbrc.2007.10.197, PII S0006291X07023728
    • Ohshiro H, Tonai-Kachi H, Ichikawa K (2008) GPR35 is a functional receptor in rat dorsal root ganglion neurons. Biochem Biophys Res Commun 365: 344-348. doi:10.1016/j.bbrc.2007.10.197. PubMed: 17996730. (Pubitemid 350137295)
    • (2008) Biochemical and Biophysical Research Communications , vol.365 , Issue.2 , pp. 344-348
    • Ohshiro, H.1    Tonai-Kachi, H.2    Ichikawa, K.3
  • 4
    • 33748314488 scopus 로고    scopus 로고
    • Zaprinast, a well-known cyclic guanosine monophosphate-specific phosphodiesterase inhibitor, is an agonist for GPR35
    • DOI 10.1016/j.febslet.2006.08.015, PII S0014579306009756
    • Taniguchi Y, Tonai-Kachi H, Shinjo K (2006) Zaprinast, a well-known cyclic guanosine monophosphate-specific phosphodiesterase inhibitor, is an agonist for GPR35. FEBS Lett 580: 5003-5008. doi:10.1016/j.febslet.2006.08.015. PubMed: 16934253. (Pubitemid 44332369)
    • (2006) FEBS Letters , vol.580 , Issue.21 , pp. 5003-5008
    • Taniguchi, Y.1    Tonai-Kachi, H.2    Shinjo, K.3
  • 5
  • 6
    • 84857627249 scopus 로고    scopus 로고
    • Kynurenic acid: A metabolite with multiple actions and multiple targets in brain and periphery
    • doi:10.1007/s00702-011-0763-x. PubMed: 22215208
    • Moroni F, Cozzi A, Sili M, Mannaioni G (2012) Kynurenic acid: a metabolite with multiple actions and multiple targets in brain and periphery. J Neural Transm 119: 133-139. doi:10.1007/s00702-011-0763-x. PubMed: 22215208.
    • (2012) J Neural Transm , vol.119 , pp. 133-139
    • Moroni, F.1    Cozzi, A.2    Sili, M.3    Mannaioni, G.4
  • 7
    • 84873412061 scopus 로고    scopus 로고
    • An expanding range of targets for kynurenine metabolites of tryptophan
    • doi:10.1016/j.tips.2012.09.006. PubMed: 23123095
    • Stone TW, Stoy N, Darlington LG (2013) An expanding range of targets for kynurenine metabolites of tryptophan. Trends Pharmacol Sci 34: 136-143. doi:10.1016/j.tips.2012.09.006. PubMed: 23123095.
    • (2013) Trends Pharmacol Sci , vol.34 , pp. 136-143
    • Stone, T.W.1    Stoy, N.2    Darlington, L.G.3
  • 8
    • 0035477818 scopus 로고    scopus 로고
    • Increased cortical kynurenate content in schizophrenia
    • DOI 10.1016/S0006-3223(01)01078-2, PII S0006322301010782
    • Schwarcz R, Rassoulpour A, Wu HQ, Medoff D, Tamminga CA et al. (2001) Increased cortical kynurenate content in schizophrenia. Biol Psychiatry 50: 521-530. doi:10.1016/S0006-3223(01)01078-2. PubMed: 11600105. (Pubitemid 32971883)
    • (2001) Biological Psychiatry , vol.50 , Issue.7 , pp. 521-530
    • Schwarcz, R.1    Rassoulpour, A.2    Wu, H.-Q.3    Medoff, D.4    Tamminga, C.A.5    Roberts, R.C.6
  • 9
    • 0035798252 scopus 로고    scopus 로고
    • Kynurenic acid levels ae elevated in the cerebrospinal fluid of patients with schizophrenia
    • DOI 10.1016/S0304-3940(01)02242-X, PII S030439400102242X
    • Erhardt S, Blennow K, Nordin C, Skogh E, Lindström LH et al. (2001) Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia. Neurosci Lett 313: 96-98. doi:10.1016/S0304-3940(01)02242-X. PubMed: 11684348. (Pubitemid 32973903)
    • (2001) Neuroscience Letters , vol.313 , Issue.1-2 , pp. 96-98
    • Erhardt, S.1    Blennow, K.2    Nordin, C.3    Skogh, E.4    Lindstrom, L.H.5    Engberg, G.6
  • 10
    • 0036734822 scopus 로고    scopus 로고
    • Kynurenine 3-mono-oxygenase inhibitors attenuate post-ischemic neuronal death in organotypic hippocampal slice cultures
    • doi:10.1046/j.1471-4159.2002.01090.x. PubMed: 12354294
    • Carpenedo R, Meli E, Peruginelli F, Pellegrini-Giampietro DE, Moroni F (2002) Kynurenine 3-mono-oxygenase inhibitors attenuate post-ischemic neuronal death in organotypic hippocampal slice cultures. J Neurochem 82: 1465-1471. doi:10.1046/j.1471-4159.2002.01090.x. PubMed: 12354294.
    • (2002) J Neurochem , vol.82 , pp. 1465-1471
    • Carpenedo, R.1    Meli, E.2    Peruginelli, F.3    Pellegrini-Giampietro, D.E.4    Moroni, F.5
  • 11
    • 84862603083 scopus 로고    scopus 로고
    • Kynurenines in the mammalian brain: When physiology meets pathology
    • doi:10.1038/nrn3257. PubMed: 22678511
    • Schwarcz R, Bruno JP, Muchowski PJ, Wu HQ (2012) Kynurenines in the mammalian brain: when physiology meets pathology. Nat Rev Neurosci 13: 465-477. doi:10.1038/nrn3257. PubMed: 22678511.
    • (2012) Nat Rev Neurosci , vol.13 , pp. 465-477
    • Schwarcz, R.1    Bruno, J.P.2    Muchowski, P.J.3    Wu, H.Q.4
  • 12
    • 77951620943 scopus 로고    scopus 로고
    • GPR35 is a novel lysophosphatidic acid receptor
    • doi:10.1016/j.bbrc.2010.03.169. PubMed: 20361937
    • Oka S, Ota R, Shima M, Yamashita A, Sugiura T (2010) GPR35 is a novel lysophosphatidic acid receptor. Biochem Biophys Res Commun 395: 232-237. doi:10.1016/j.bbrc.2010.03.169. PubMed: 20361937.
    • (2010) Biochem Biophys Res Commun , vol.395 , pp. 232-237
    • Oka, S.1    Ota, R.2    Shima, M.3    Yamashita, A.4    Sugiura, T.5
  • 13
    • 78649881120 scopus 로고    scopus 로고
    • Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Galpha and beta-arrestin-2
    • doi:10.1111/j.1476-5381.2010.01082.x. PubMed: 20958291
    • Jenkins L, Alvarez-Curto E, Campbell K, de Munnik S, Canals M et al. (2011) Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Galpha and beta-arrestin-2. Br J Pharmacol 162: 733-748. doi:10.1111/j.1476-5381.2010.01082.x. PubMed: 20958291.
    • (2011) Br J Pharmacol , vol.162 , pp. 733-748
    • Jenkins, L.1    Alvarez-Curto, E.2    Campbell, K.3    De Munnik, S.4    Canals, M.5
  • 14
    • 77957228214 scopus 로고    scopus 로고
    • Targeting of the orphan receptor GPR35 by pamoic acid: A potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity
    • doi:10.1124/mol.110.066746. PubMed: 20826425
    • Zhao P, Sharir H, Kapur A, Cowan A, Geller EB et al. (2010) Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Mol Pharmacol 78: 560-568. doi:10.1124/mol.110.066746. PubMed: 20826425.
    • (2010) Mol Pharmacol , vol.78 , pp. 560-568
    • Zhao, P.1    Sharir, H.2    Kapur, A.3    Cowan, A.4    Geller, E.B.5
  • 15
    • 77953577324 scopus 로고    scopus 로고
    • G-protein-coupled receptor 35 is a target of the asthma drugs cromolyn disodium and nedocromil sodium
    • doi: 10.1159/000314164. PubMed: 20559017
    • Yang Y, Lu JY, Wu X, Summer S, Whoriskey J et al. (2010) G-protein-coupled receptor 35 is a target of the asthma drugs cromolyn disodium and nedocromil sodium. Pharmacology 86: 1-5. doi: 10.1159/000314164. PubMed: 20559017.
    • (2010) Pharmacology , vol.86 , pp. 1-5
    • Yang, Y.1    Lu, J.Y.2    Wu, X.3    Summer, S.4    Whoriskey, J.5
  • 16
    • 80054935789 scopus 로고    scopus 로고
    • Discovery of 2-(4-methylfuran-2(5H)-ylidene)malononitrile and thieno[3,2-b]thiophene-2-carboxylic acid derivatives as G protein-coupled receptor 35 (GPR35) agonists
    • doi:10.1021/jm200999f. PubMed: 21950657
    • Deng H, Hu H, He M, Hu J, Niu W et al. (2011) Discovery of 2-(4-methylfuran-2(5H)-ylidene)malononitrile and thieno[3,2-b]thiophene-2- carboxylic acid derivatives as G protein-coupled receptor 35 (GPR35) agonists. J Med Chem 54: 7385-7396. doi:10.1021/jm200999f. PubMed: 21950657.
    • (2011) J Med Chem , vol.54 , pp. 7385-7396
    • Deng, H.1    Hu, H.2    He, M.3    Hu, J.4    Niu, W.5
  • 17
    • 79958142575 scopus 로고    scopus 로고
    • Tyrphostin analogs are GPR35 agonists
    • doi:10.1016/j.febslet.2011.05.026. PubMed: 21601572
    • Deng H, Hu H, Fang Y (2011) Tyrphostin analogs are GPR35 agonists. FEBS Lett 585: 1957-1962. doi:10.1016/j.febslet.2011.05.026. PubMed: 21601572.
    • (2011) FEBS Lett , vol.585 , pp. 1957-1962
    • Deng, H.1    Hu, H.2    Fang, Y.3
  • 18
    • 0027486072 scopus 로고
    • Neuropharmacology of quinolinic and kynurenic acids
    • PubMed: 8248282
    • Stone TW (1993) Neuropharmacology of quinolinic and kynurenic acids. Pharmacol Rev 45: 309-379. PubMed: 8248282.
    • (1993) Pharmacol Rev , vol.45 , pp. 309-379
    • Stone, T.W.1
  • 19
    • 0035478066 scopus 로고    scopus 로고
    • The brain metabolite kynurenic acid inhibits α7 nicotinic receptor activity and increases non-α7 nicotinic receptor expression: Physiopathological implications
    • Hilmas C, Pereira EFR, Alkondon M, Rassoulpour A, Schwarcz R et al. (2001) The brain metabolite kynurenic acid inhibits α7 nicotinic receptor activity and increases non α7 nicotinic receptor expression: physiopathological implications. J Neurosci 21: 7463-7473. PubMed: 11567036. (Pubitemid 32904945)
    • (2001) Journal of Neuroscience , vol.21 , Issue.19 , pp. 7463-7473
    • Hilmas, C.1    Pereira, E.F.R.2    Alkondon, M.3    Rassoulpour, A.4    Schwarcz, R.5    Albuquerque, E.X.6
  • 21
    • 79954585445 scopus 로고    scopus 로고
    • G-protein coupled receptor 35 (GPR35) activation and inflammatory pain: Studies on the antinociceptive effects of kynurenic acid and zaprinast
    • PubMed: 21110987
    • Cosi C, Mannaioni G, Cozzi A, Carlà V, Sili M et al. (2011) G-protein coupled receptor 35 (GPR35) activation and inflammatory pain: Studies on the antinociceptive effects of kynurenic acid and zaprinast. Neuropharmacology 60: 1227-1231. PubMed: 21110987.
    • (2011) Neuropharmacology , vol.60 , pp. 1227-1231
    • Cosi, C.1    Mannaioni, G.2    Cozzi, A.3    Carlà, V.4    Sili, M.5
  • 22
    • 0032858698 scopus 로고    scopus 로고
    • A novel effect of cyclic AMP on capacitative Ca2+ entry in cultured rat cerebellar astrocytes
    • PubMed: 10461927
    • Wu ML, Chen WH, Liu IH, Tseng CD, Wang SM (1999) A novel effect of cyclic AMP on capacitative Ca2+ entry in cultured rat cerebellar astrocytes. J Neurochem 73: 1318-1328. PubMed: 10461927.
    • (1999) J Neurochem , vol.73 , pp. 1318-1328
    • Wu, M.L.1    Chen, W.H.2    Liu, I.H.3    Tseng, C.D.4    Wang, S.M.5
  • 24
    • 7444225294 scopus 로고    scopus 로고
    • Functional bradykinin B1 receptors are expressed in nociceptive neurones and are upregulated by the neurotrophin GDNF
    • DOI 10.1113/jphysiol.2004.067462
    • Vellani V, Zachrisson O, McNaughton PA (2004) Functional bradykinin B1 receptors are expressed in nociceptive neurones and are upregulated by the neurotrophin GDNF. J Physiol 560: 391-401. doi: 10.1113/jphysiol.2004.067462. PubMed: 15319421. (Pubitemid 39440102)
    • (2004) Journal of Physiology , vol.560 , Issue.2 , pp. 391-401
    • Vellani, V.1    Zachrisson, O.2    McNaughton, P.A.3
  • 25
    • 0035937155 scopus 로고    scopus 로고
    • Signaling pathways underlying muscarinic receptor-induced [Ca2+]i oscillations in HEK293 cells
    • doi:10.1074/jbc.M007524200. PubMed: 11096083
    • Luo D, Broad LM, Bird GS, Putney JWJ (2001) Signaling pathways underlying muscarinic receptor-induced [Ca2+]i oscillations in HEK293 cells. J Biol Chem 276: 5613-5621. doi:10.1074/jbc.M007524200. PubMed: 11096083.
    • (2001) J Biol Chem , vol.276 , pp. 5613-5621
    • Luo, D.1    Broad, L.M.2    Bird, G.S.3    Putney, J.W.J.4
  • 26
    • 0024346141 scopus 로고
    • Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. Evidence that an intracellular calcium pool, and not an inositol phosphate, regulates calcium fluxes at the plasma membrane
    • Takemura H, Hughes AR, Thastrup O, Putney JWJ (1989) Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. Evidence that an intracellular calcium pool and not an inositol phosphate regulates calcium fluxes at the plasma membrane. J Biol Chem 264: 12266-12271. PubMed: 2663854. (Pubitemid 19191112)
    • (1989) Journal of Biological Chemistry , vol.264 , Issue.21 , pp. 12266-12271
    • Takemura, H.1    Hughes, A.R.2    Thastrup, O.3    Putney Jr., J.W.4
  • 27
    • 0035882474 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function
    • Mannaioni G, Marino MJ, Valenti O, Traynelis SF, Conn PJ (2001) Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function. J Neurosci 21: 5925-5934. PubMed: 11487615. (Pubitemid 32737725)
    • (2001) Journal of Neuroscience , vol.21 , Issue.16 , pp. 5925-5934
    • Mannaioni, G.1    Marino, M.J.2    Valenti, O.3    Traynelis, S.F.4    Conn, P.J.5
  • 28
    • 84876260705 scopus 로고    scopus 로고
    • MPP(+) -dependent inhibition of I(h) reduces spontaneous activity and enhances EPSP summation in nigral dopamine neurons
    • Epub ahead of print
    • Masi A, Narducci R, Landucci E, Moroni F, Mannaioni G (2013) MPP(+) -dependent inhibition of I(h) reduces spontaneous activity and enhances EPSP summation in nigral dopamine neurons. Br J Pharmacol Epub ahead of print.
    • (2013) Br J Pharmacol
    • Masi, A.1    Narducci, R.2    Landucci, E.3    Moroni, F.4    Mannaioni, G.5
  • 29
    • 79954585445 scopus 로고    scopus 로고
    • G-protein coupled receptor 35 (GPR35) activation and inflammatory pain: Studies on the antinociceptive effects of kynurenic acid and zaprinast
    • doi:10.1016/j.neuropharm.2010.11.014. PubMed: 21110987
    • Cosi C, Mannaioni G, Cozzi A, Carlà V, Sili M et al. (2011) G-protein coupled receptor 35 (GPR35) activation and inflammatory pain: Studies on the antinociceptive effects of kynurenic acid and zaprinast. Neuropharmacology 60: 1227-1231. doi:10.1016/j.neuropharm.2010.11.014. PubMed: 21110987.
    • (2011) Neuropharmacology , vol.60 , pp. 1227-1231
    • Cosi, C.1    Mannaioni, G.2    Cozzi, A.3    Carlà, V.4    Sili, M.5
  • 30
    • 0030873754 scopus 로고    scopus 로고
    • Type 2 metabotropic glutamate receptors (mGluRs) tonically inhibit transmitter release in rat caudate nucleus: In vivo studies with (2S,1S, 2S,3R)-2-(2-Carboxy-3-phenylcyclopropyl)glycine (PCCG-IV), a new potent and selective antagonist
    • doi: 10.1111/j.1460-9568.1997.tb01489.x. PubMed: 9240392
    • Cozzi A, Attucci S, Peruginelli F, Marinozzi M, Pellicciari R et al. (1997) Type 2 metabotropic glutamate receptors (mGluRs) tonically inhibit transmitter release in rat caudate nucleus: in vivo studies with (2S,1S, 2S,3R)-2-(2-Carboxy-3-phenylcyclopropyl)glycine (PCCG-IV), a new potent and selective antagonist. Eur J Neurosci 9: 1350-1355. doi: 10.1111/j.1460-9568. 1997.tb01489.x. PubMed: 9240392.
    • (1997) Eur J Neurosci , vol.9 , pp. 1350-1355
    • Cozzi, A.1    Attucci, S.2    Peruginelli, F.3    Marinozzi, M.4    Pellicciari, R.5
  • 32
    • 0030221944 scopus 로고    scopus 로고
    • Calcium signalling in glial cells
    • DOI 10.1016/0166-2236(96)10048-5
    • Verkhratsky A, Kettenmann H (1996) Calcium signalling in glial cells. Trends Neurosci 19: 346-352. doi:10.1016/0166-2236(96)10048-5. PubMed: 8843604. (Pubitemid 26349064)
    • (1996) Trends in Neurosciences , vol.19 , Issue.8 , pp. 346-352
    • Verkhratsky, A.1    Kettenmann, H.2
  • 33
    • 0037289695 scopus 로고    scopus 로고
    • 2+ interplay: A matter of oscillation patterns
    • DOI 10.1016/S0166-2236(02)00017-6, PII S0166223602000176
    • Zaccolo M, Pozzan T (2003) cAMP and Ca2+ interplay: a matter of oscillation patterns. Trends Neurosci 26: 53-55. doi:10.1016/S0166-2236(02) 00017-6. PubMed: 12536124. (Pubitemid 36110535)
    • (2003) Trends in Neurosciences , vol.26 , Issue.2 , pp. 53-55
    • Zaccolo, M.1    Pozzan, T.2
  • 34
    • 64049118708 scopus 로고    scopus 로고
    • Store-operated cyclic AMP signalling mediated by STIM1
    • doi:10.1038/ncb1850. PubMed: 19287379
    • Lefkimmiatis K, Srikanthan M, Maiellaro I, Moyer MP, Curci S et al. (2009) Store-operated cyclic AMP signalling mediated by STIM1. Nat Cell Biol 11: 433-442. doi:10.1038/ncb1850. PubMed: 19287379.
    • (2009) Nat Cell Biol , vol.11 , pp. 433-442
    • Lefkimmiatis, K.1    Srikanthan, M.2    Maiellaro, I.3    Moyer, M.P.4    Curci, S.5
  • 35
    • 84866115013 scopus 로고    scopus 로고
    • Kynurenic acid inhibits glutamatergic transmission to CA1 pyramidal neurons via α7 nAChR-dependent and -independent mechanisms
    • doi:10.1016/j.bcp.2012.07.030. PubMed: 22889930
    • Banerjee J, Alkondon M, Albuquerque EX (2012) Kynurenic acid inhibits glutamatergic transmission to CA1 pyramidal neurons via α7 nAChR-dependent and -independent mechanisms. Biochem Pharmacol 84: 1078-1087. doi:10.1016/j.bcp.2012.07.030. PubMed: 22889930.
    • (2012) Biochem Pharmacol , vol.84 , pp. 1078-1087
    • Banerjee, J.1    Alkondon, M.2    Albuquerque, E.X.3
  • 36
    • 67650681778 scopus 로고    scopus 로고
    • Electrophysiological characterisation of the actions of kynurenic acid at ligand-gated ion channels
    • doi:10.1016/j.neuropharm.2009.06.003. PubMed: 19523966
    • Mok MHS, Fricker ACF, Weil A, Kew JN (2009) Electrophysiological characterisation of the actions of kynurenic acid at ligand-gated ion channels. Neuropharmacology 57: 242-249. doi:10.1016/j.neuropharm.2009.06.003. PubMed: 19523966.
    • (2009) Neuropharmacology , vol.57 , pp. 242-249
    • Mok, M.H.S.1    Fricker, A.C.F.2    Weil, A.3    Kew, J.N.4
  • 37
    • 0028067678 scopus 로고
    • The nitric oxide-cyclic GMP pathway and synaptic depression in rat hippocampal slices
    • DOI 10.1111/j.1460-9568.1994.tb00543.x
    • Boulton CL, Irving AJ, Southam E, Potier B, Garthwaite J et al. (1994) The nitric oxide-cyclic GMP pathway and synaptic depression in rat hippocampal slices. Eur J Neurosci 6: 1528-1535. doi:10.1111/j.1460-9568.1994.tb00543.x. PubMed: 7850017. (Pubitemid 24310360)
    • (1994) European Journal of Neuroscience , vol.6 , Issue.10 , pp. 1528-1535
    • Boulton, C.L.1    Irving, A.J.2    Southam, E.3    Potier, B.4    Garthwaite, J.5    Collingridge, G.L.6
  • 38
    • 0028138709 scopus 로고
    • Activation of the NO-cGMP signalling pathway depresses hippocampal synaptic transmission through an adenosine receptor-dependent mechanism
    • DOI 10.1016/0028-3908(94)90056-6
    • Broome MR, Collingridge GL, Irving AJ (1994) Activation of the NOcGMP signalling pathway depresses hippocampal synaptic transmission through an adenosine receptor-dependent mechanism. Neuropharmacology 33: 1511-1513. doi: 10.1016/0028-3908(94)90056-6. PubMed: 7870292. (Pubitemid 24353748)
    • (1994) Neuropharmacology , vol.33 , Issue.11 , pp. 1511-1513
    • Broome, M.R.1    Collingridge, G.L.2    Irving, A.J.3
  • 39
    • 0025938291 scopus 로고
    • Modulation of quinolinic and kynurenic acid content in the rat brain: Effects of endotoxins and nicotinylalanine
    • Moroni F, Russi P, Gallo-Mezo MA, Moneti G, Pellicciari R (1991) Modulation of quinolinic and kynurenic acid content in the rat brain: effects of endotoxins and nicotinylalanine. J Neurochem 57: 1630-1635. doi:10.1111/j.1471-4159.1991.tb06361.x. PubMed: 1833509. (Pubitemid 21922799)
    • (1991) Journal of Neurochemistry , vol.57 , Issue.5 , pp. 1630-1635
    • Moroni, F.1    Russi, P.2    Gallo-Mezo, M.A.3    Moneti, G.4    Pellicciari, R.5
  • 40
    • 0028305047 scopus 로고
    • Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenate and have sedative and anticonvulsant activities
    • DOI 10.1016/0306-4522(94)90227-5
    • Carpenedo R, Chiarugi A, Russi P, Lombardi G, Carlà V et al. (1994) Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenic acid and have sedative and anticonvulsant activities. Neuroscience 61: 237-244. doi: 10.1016/0306-4522(94)90227-5. PubMed: 7969905. (Pubitemid 24219003)
    • (1994) Neuroscience , vol.61 , Issue.2 , pp. 237-244
    • Carpenedo, R.1
  • 41
    • 0025777901 scopus 로고
    • Comparative behavioral and pharmacological studies with centrally administered kynurenine and kynurenic acid in rats
    • doi:10.1016/0014-2999(91)90436-T. PubMed: 1893912
    • Vécsei L, Beal MF (1991) Comparative behavioral and pharmacological studies with centrally administered kynurenine and kynurenic acid in rats. Eur J Pharmacol 196: 239-246. doi:10.1016/0014-2999(91)90436-T. PubMed: 1893912.
    • (1991) Eur J Pharmacol , vol.196 , pp. 239-246
    • Vécsei, L.1    Beal, M.F.2
  • 42
    • 7444239057 scopus 로고    scopus 로고
    • Kynurenine administered together with probenecid markedly inhibits pentylenetetrazol-induced seizures. An electrophysiological and behavioural study
    • DOI 10.1016/j.neuropharm.2004.06.007, PII S0028390804001601
    • Németh H, Robotka H, Kis Z, Rózsa E, Janáky T et al. (2004) Kynurenine administered together with probenecid markedly inhibits pentylenetetrazol-induced seizures. An electrophysiological and behavioural study. Neuropharmacology 47: 916-925. doi:10.1016/j.neuropharm.2004.06.007. PubMed: 15527825. (Pubitemid 39440985)
    • (2004) Neuropharmacology , vol.47 , Issue.6 , pp. 916-925
    • Nemeth, H.1    Robotka, H.2    Kis, Z.3    Rozsa, E.4    Janaky, T.5    Somlai, C.6    Marosi, M.7    Farkas, T.8    Toldi, J.9    Vecsei, L.10
  • 43
    • 0033502043 scopus 로고    scopus 로고
    • Kynurenine hydroxylase inhibitors reduce ischemic brain damage: Studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4- (nitrophenyl)thiazol-2YL]-benzenesulfonamide (Ro 61-8048) in models of focal or global brain ischemia
    • Cozzi A, Carpenedo R, Moroni F (1999) Kynurenine hydroxylase inhibitors reduce ischemic brain damage: studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4-(nitrophenyl)thiazol-2yl]-benzenesulfonamide (RO 61-8048) in models of focal or global ischemia. J Cereb Blood Flow Metab 19: 771-777. PubMed: 10413032. (Pubitemid 30159803)
    • (1999) Journal of Cerebral Blood Flow and Metabolism , vol.19 , Issue.7 , pp. 771-777
    • Cozzi, A.1    Carpenedo, R.2    Moroni, F.3
  • 44
    • 0030035748 scopus 로고    scopus 로고
    • Kynurenine disposition in blood and brain of mice: Effects of selective inhibitors of kynurenine hydroxylase and of kynureninase
    • Chiarugi A, Carpenedo R, Moroni F (1996) Kynurenine disposition in blood and brain of mice: effects of selective inhibitors of kynurenine hydroxylase and of kynureninase. J Neurochem 69: 692-698. PubMed: 8764597. (Pubitemid 26255666)
    • (1996) Journal of Neurochemistry , vol.67 , Issue.2 , pp. 692-698
    • Chiarugi, A.1    Carpenedo, R.2    Moroni, F.3
  • 45
    • 0026535226 scopus 로고
    • Neuroprotective effects of L-kynurenine on hypoxia-ischemia and NMDA lesions in neonatal rats
    • doi:10.1038/jcbfm.1992.57. PubMed: 1569135
    • Nozaki K, Beal MF (1992) Neuroprotective effects of L-kynurenine on hypoxia-ischemia and NMDA lesions in neonatal rats. J Cereb Blood Flow Metab 12: 400-407. doi:10.1038/jcbfm.1992.57. PubMed: 1569135.
    • (1992) J Cereb Blood Flow Metab , vol.12 , pp. 400-407
    • Nozaki, K.1    Beal, M.F.2
  • 46
    • 79958021894 scopus 로고    scopus 로고
    • Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration
    • doi:10.1016/j.cell. 2011.05.020. PubMed: 21640374
    • Zwilling D, Huang SY, Sathyasaikumar KV, Notarangelo FM, Guidetti P et al. (2011) Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration. Cell 145: 863-874. doi:10.1016/j.cell. 2011.05.020. PubMed: 21640374.
    • (2011) Cell , vol.145 , pp. 863-874
    • Zwilling, D.1    Huang, S.Y.2    Sathyasaikumar, K.V.3    Notarangelo, F.M.4    Guidetti, P.5
  • 47
    • 79958044624 scopus 로고    scopus 로고
    • The kynurenine pathway modulates neurodegeneration in a Drosophila model of Huntington's disease
    • doi: 10.1016/j.cub.2011.04.028. PubMed: 21636279
    • Campesan S, Green EW, Breda C, Sathyasaikumar KV, Muchowski PJ et al. (2011) The kynurenine pathway modulates neurodegeneration in a Drosophila model of Huntington's disease. Curr Biol 21: 961-966. doi: 10.1016/j.cub.2011.04.028. PubMed: 21636279.
    • (2011) Curr Biol , vol.21 , pp. 961-966
    • Campesan, S.1    Green, E.W.2    Breda, C.3    Sathyasaikumar, K.V.4    Muchowski, P.J.5
  • 48
    • 33751558659 scopus 로고    scopus 로고
    • Astrocytic localization of kynurenine aminotransferase II in the rat brain visualized by immunocytochemistry
    • DOI 10.1002/glia.20432
    • Guidetti P, Hoffman GE, Melendez-Ferro M, Albuquerque EX, Schwarcz R (2007) Astrocytic localization of kynurenine aminotransferase II in the rat brain visualized by immunocytochemistry. Glia 55: 78-92. doi:10.1002/glia.20432. PubMed: 17024659. (Pubitemid 44845511)
    • (2007) GLIA , vol.55 , Issue.1 , pp. 78-92
    • Guidetti, P.1    Hoffman, G.E.2    Melendez-Ferro, M.3    Albuquerque, E.X.4    Schwarcz, R.5
  • 49
    • 77953617514 scopus 로고    scopus 로고
    • Reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior
    • PubMed: 20336058
    • Potter MC, Elmer GI, Bergeron R, Albuquerque EX, Guidetti P et al. (2010) Reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior. Neuropsychopharmacology 35: 1734-1742. PubMed: 20336058.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1734-1742
    • Potter, M.C.1    Elmer, G.I.2    Bergeron, R.3    Albuquerque, E.X.4    Guidetti, P.5
  • 50
    • 0037289695 scopus 로고    scopus 로고
    • 2+ interplay: A matter of oscillation patterns
    • DOI 10.1016/S0166-2236(02)00017-6, PII S0166223602000176
    • Zaccolo M, Pozzan T (2003) cAMP and Ca2+ interplay: a matter of oscillation patterns. Trends Neurosci 26: 53-55. doi:10.1016/S0166-2236(02) 00017-6. PubMed: 12536124. (Pubitemid 36110535)
    • (2003) Trends in Neurosciences , vol.26 , Issue.2 , pp. 53-55
    • Zaccolo, M.1    Pozzan, T.2
  • 51
    • 84856297627 scopus 로고    scopus 로고
    • Organization of cAMP signalling microdomains for optimal regulation by Ca2+ entry
    • doi: 10.1042/BST20110613. PubMed: 22260699
    • Willoughby D (2012) Organization of cAMP signalling microdomains for optimal regulation by Ca2+ entry. Biochem Soc Trans 40: 246-250. doi: 10.1042/BST20110613. PubMed: 22260699.
    • (2012) Biochem Soc Trans , vol.40 , pp. 246-250
    • Willoughby, D.1
  • 52
    • 37349129072 scopus 로고    scopus 로고
    • Inhibition of N-type calcium channels by activation of GPR35, an orphan receptor, heterologously expressed in rat sympathetic neurons
    • DOI 10.1124/jpet.107.127266
    • Guo J, Williams DJ, Puhl HL3, Ikeda SR (2008) Inhibition of N-type calcium channels by activation of GPR35, an orphan receptor, heterologously expressed in rat sympathetic neurons. J Pharmacol Exp Ther 324: 342-351. (Pubitemid 350294182)
    • (2008) Journal of Pharmacology and Experimental Therapeutics , vol.324 , Issue.1 , pp. 342-351
    • Guo, J.1    Williams, D.J.2    Puhl III, H.L.3    Ikeda, S.R.4
  • 53
    • 67349136603 scopus 로고    scopus 로고
    • The trinity of Ca2+ sources for the exocytotic glutamate release from astrocytes
    • doi:10.1016/j.neuint.2008.12.018. PubMed: 19171170
    • Reyes RC, Parpura V (2009) The trinity of Ca2+ sources for the exocytotic glutamate release from astrocytes. Neurochem Int 55: 2-8. doi:10.1016/j.neuint. 2008.12.018. PubMed: 19171170.
    • (2009) Neurochem Int , vol.55 , pp. 2-8
    • Reyes, R.C.1    Parpura, V.2
  • 54
    • 34548203204 scopus 로고    scopus 로고
    • Astrocytes potentiate transmitter release at single hippocampal synapses
    • DOI 10.1126/science.1144640
    • Perea G, Araque A (2007) Astrocytes potentiate transmitter release at single hippocampal synapses. Science 317: 1083-1086. doi:10.1126/science. 1144640. PubMed: 17717185. (Pubitemid 47330192)
    • (2007) Science , vol.317 , Issue.5841 , pp. 1083-1086
    • Perea, G.1    Araque, A.2


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