PDE4B mediates local feedback regulation of β1-adrenergic cAMP signaling in a sarcolemmal compartment of cardiac myocytes

Journal of Cell Science

Volumn 127, Issue 5, 2014, Pages 1033-1042

  Mika, Delphine ^a   Richter, Wito ^a   Westenbroek, Ruth E ^b   Catterall, William A ^b   Conti, Marco ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

CAMP adrenergic receptors; Cardiac myocytes; Compartmentalization; Cyclic nucleotide phosphodiesterase; PDE

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; CALCIUM CHANNEL L TYPE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP PHOSPHODIESTERASE 4B; PHOSPHODIESTERASE; RYANODINE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOACCUMULATION; CALCIUM CELL LEVEL; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXCITATION CONTRACTION COUPLING; FEEDBACK SYSTEM; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEART MUSCLE CELL; MOLECULAR SENSOR; MOUSE; NEGATIVE FEEDBACK; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SARCOLEMMA; SIGNAL TRANSDUCTION; WILD TYPE;

CAMP; CARDIAC MYOCYTES; COMPARTMENTALIZATION; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; PDE; Β-ADRENERGIC RECEPTORS;

ADRENERGIC BETA-2 RECEPTOR ANTAGONISTS; ANIMALS; CALCIUM; CELL MEMBRANE; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; ENZYME ACTIVATION; FEEDBACK, PHYSIOLOGICAL; IMIDAZOLES; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOLEMMA; SECOND MESSENGER SYSTEMS;

EID: 84896690502     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.140251     Document Type: Article

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